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The map label for this gene is dgdR [H]

Identifier: 73541298

GI number: 73541298

Start: 1730692

End: 1731555

Strand: Reverse

Name: dgdR [H]

Synonym: Reut_A1608

Alternate gene names: 73541298

Gene position: 1731555-1730692 (Counterclockwise)

Preceding gene: 73541300

Following gene: 73541297

Centisome position: 45.49

GC content: 65.74

Gene sequence:

>864_bases
ATGACCACTGAGATGAAAGCCCTCGACGTCGACGTCCTGACCATGATCATTGCCGTCGCAGACTCCGGCACCATCAGCCG
GGCTGCCGACCTCGTGCATCGCTCGCAGTCGGCCGTGAGCATGCAGATCAAAACGCTGGAATCGGCGCTCGGCAAAGCGC
TCTTCATACGCAAGCCACGCAGCGTGATTCCGACGCAGGACGGTGAGGTTCTGCTGACGTATGCGCGCCGGATCATTGCC
CTTCGCGATGAGGCGTGGGCGGCGATCGTGCGGCCCGACGTCACGGGCCGCGTGGTGATCGGCGTACCTGACGATTACGC
ATCGTCGCTGTTCCCGCCCATTCTGAAGAAGTTCTCGGCCACCTACCCCAAGGTCGAGATCCAGGTCATCGGGCTGCCCA
GCGTCGCGCTCGCGCCGATGCTGCGCGATGGCACGGTGGATCTCGTCTGCGCGACGCGCGTCAAAGGGCTGACCGGCGAG
TTTCTGCGGCATGAGCCAATGGTGTGGGCAACCGACCCGGGGTCCACGGAAATCTGGCGAGAGCGGCCCCTCCCCATCGC
CGTGTTCCTGCCGGGAAGCGTCGCGCGCGAAAAGGCGATCCGAAGCCTTGAGCGGGCCAAGATCGCGTATCGCACCTCCT
ATGAGAGCCCCAGCCTGCTGGGCCTGCTGACGATGGCGCGCGCCGGCCTTGCCATCACCCCGCTGGCGCGGTGCGCGGTG
CCGTCCGACTTTACGCTGCTCGGGGCGGCGCAGGGTCTGCCCGAGATCGGCACGCTTGAGATCATCCTTGCGCGCAGTGT
CACGTCGAACCGGCCGCCCTGCGATTTTCTGGCGGAGCGCATCGTCGCCGAGTTGCACGCATAA

Upstream 100 bases:

>100_bases
ATGACTCCGTTTTGCGAACTTTGCTGCAGCGCACGAAAAAAGAAAATCGCATAATATTGATGGAATCCTTCAGATTTTCT
GATGCCTCCCGGACAAACGC

Downstream 100 bases:

>100_bases
ACCGATAGCGAGCCAGCCCGAGGGGCTGCTCGTGCAAGACCAATGCCGCGTCCCCACGCAGGCGGTCGCTTATCGCACAC
TCCGTGCGTGGCATGCGGCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: 2,2-dialkylglycine decarboxylase repressor [H]

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MTTEMKALDVDVLTMIIAVADSGTISRAADLVHRSQSAVSMQIKTLESALGKALFIRKPRSVIPTQDGEVLLTYARRIIA
LRDEAWAAIVRPDVTGRVVIGVPDDYASSLFPPILKKFSATYPKVEIQVIGLPSVALAPMLRDGTVDLVCATRVKGLTGE
FLRHEPMVWATDPGSTEIWRERPLPIAVFLPGSVAREKAIRSLERAKIAYRTSYESPSLLGLLTMARAGLAITPLARCAV
PSDFTLLGAAQGLPEIGTLEIILARSVTSNRPPCDFLAERIVAELHA

Sequences:

>Translated_287_residues
MTTEMKALDVDVLTMIIAVADSGTISRAADLVHRSQSAVSMQIKTLESALGKALFIRKPRSVIPTQDGEVLLTYARRIIA
LRDEAWAAIVRPDVTGRVVIGVPDDYASSLFPPILKKFSATYPKVEIQVIGLPSVALAPMLRDGTVDLVCATRVKGLTGE
FLRHEPMVWATDPGSTEIWRERPLPIAVFLPGSVAREKAIRSLERAKIAYRTSYESPSLLGLLTMARAGLAITPLARCAV
PSDFTLLGAAQGLPEIGTLEIILARSVTSNRPPCDFLAERIVAELHA
>Mature_286_residues
TTEMKALDVDVLTMIIAVADSGTISRAADLVHRSQSAVSMQIKTLESALGKALFIRKPRSVIPTQDGEVLLTYARRIIAL
RDEAWAAIVRPDVTGRVVIGVPDDYASSLFPPILKKFSATYPKVEIQVIGLPSVALAPMLRDGTVDLVCATRVKGLTGEF
LRHEPMVWATDPGSTEIWRERPLPIAVFLPGSVAREKAIRSLERAKIAYRTSYESPSLLGLLTMARAGLAITPLARCAVP
SDFTLLGAAQGLPEIGTLEIILARSVTSNRPPCDFLAERIVAELHA

Specific function: Not Known, Does Not Seem To Act On The Proton Translocating NADH Dehydrogenase Genes (Nuoa-N) Which Are Part Of The Lrha Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=265, Percent_Identity=32.0754716981132, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1788297, Length=139, Percent_Identity=33.0935251798561, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787806, Length=140, Percent_Identity=30.7142857142857, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1790262, Length=160, Percent_Identity=30, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790399, Length=252, Percent_Identity=28.968253968254, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI157672245, Length=142, Percent_Identity=33.0985915492958, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787601, Length=143, Percent_Identity=27.972027972028, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790208, Length=154, Percent_Identity=31.1688311688312, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI2367136, Length=121, Percent_Identity=32.2314049586777, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31078; Mature: 30947

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTEMKALDVDVLTMIIAVADSGTISRAADLVHRSQSAVSMQIKTLESALGKALFIRKPR
CCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCC
SVIPTQDGEVLLTYARRIIALRDEAWAAIVRPDVTGRVVIGVPDDYASSLFPPILKKFSA
CCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHCC
TYPKVEIQVIGLPSVALAPMLRDGTVDLVCATRVKGLTGEFLRHEPMVWATDPGSTEIWR
CCCEEEEEEEECCHHHHHHHHCCCCEEEEEECHHCCCCHHHHHCCCEEEEECCCCCHHHH
ERPLPIAVFLPGSVAREKAIRSLERAKIAYRTSYESPSLLGLLTMARAGLAITPLARCAV
CCCCCEEEECCCHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHCCCEECCHHHHCC
PSDFTLLGAAQGLPEIGTLEIILARSVTSNRPPCDFLAERIVAELHA
CCCCEEEEHHCCCCCCCCEEEEEEEHHCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTEMKALDVDVLTMIIAVADSGTISRAADLVHRSQSAVSMQIKTLESALGKALFIRKPR
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCC
SVIPTQDGEVLLTYARRIIALRDEAWAAIVRPDVTGRVVIGVPDDYASSLFPPILKKFSA
CCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHCC
TYPKVEIQVIGLPSVALAPMLRDGTVDLVCATRVKGLTGEFLRHEPMVWATDPGSTEIWR
CCCEEEEEEEECCHHHHHHHHCCCCEEEEEECHHCCCCHHHHHCCCEEEEECCCCCHHHH
ERPLPIAVFLPGSVAREKAIRSLERAKIAYRTSYESPSLLGLLTMARAGLAITPLARCAV
CCCCCEEEECCCHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHCCCEECCHHHHCC
PSDFTLLGAAQGLPEIGTLEIILARSVTSNRPPCDFLAERIVAELHA
CCCCEEEEHHCCCCCCCCEEEEEEEHHCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2180928 [H]