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The map label for this gene is fabG [H]

Identifier: 73541239

GI number: 73541239

Start: 1669876

End: 1670742

Strand: Reverse

Name: fabG [H]

Synonym: Reut_A1549

Alternate gene names: 73541239

Gene position: 1670742-1669876 (Counterclockwise)

Preceding gene: 73541243

Following gene: 73541230

Centisome position: 43.89

GC content: 65.4

Gene sequence:

>867_bases
ATGAGCGATTCAAAACAAGCCTGCGTCGCGGTAGTCACCGGCGCATCGCGCGGTGCCGGCCGGGGCATTGCACTGGCACT
CGGCGCGGCCGGCGCCACGGTATACGTGACCGGACGTACCGAGCAGGAAGGCAGCGCGCCGCTGCCGGGCACGATTCACG
CGACCGCACGCGACATCGACGCGCTCGGCGGCCGCGGTATCGCGGTGGCCTGCGACCATAGCGACGATGCGCAAGTGGCC
GCGCTGTTCCAGCGCGTGCGCGAGGAAGCGGGACGGCTCGACATCCTGGTCAACAACGCCACCTTCCTGCATGACGAACT
GATCATGCCGGGGCCCTTCTGGCAGAAGCCGCTGGAGATGACCGGCATTCTCGACGTGGGTCTGCGGTCTGGCTATGTGG
CCAGCTGGCATGCTGCGCCGATGATGGTCGCGCAGGGGAGCGGGCTGATCGTTTTCACTTCGTCATTCGGCGCCAATTGC
TATATGCACGGGCCTGCCTACGGCGCGCAGAAGGCTGGGATCGACAAGTTCGCGCATGACATGGCGGTGGACCTGCGGCC
CTATGGTGTAGCTGCGGTGTCATTGTGGATGGGGCCGCTGCGGACTGCGCGAACGATGCAGGTTTGGGAGAAGCATCCAG
ACAAATATGCGTCGTTTGCGCCGGTGGCGGAGACGCCGGAGTTCACGGGGCGCATTGTGGATGCGCTGTATCGGGATCCT
GCCTTGATGGATAAGTCCGGGAAGGTCCTGATCTGTGCGGAGGCGGCGCTGGAGTACGGGATCGTGGACGATGAGGGGGT
GCAGCCGCCGTCGTATCGGCAGGTGCTCGGCGGGCCGCCGGGGGTGCATCCGGCGATTGTTGAATAG

Upstream 100 bases:

>100_bases
GGATTAGCCGGCTTCGAACATGGCTAGTCCGAACGAGTGATGTGCTGGTTCCCCTCGAACCGCAATCTTGGAAGCGGTTC
CCATACTCAGAGGAGGAGAC

Downstream 100 bases:

>100_bases
AACGCTGATAAGGCTGTGGATTTGAGCGGTGTTGGCGCTCTTGCTGGCGTGGCTGTTTCGCCGGCGTAGCCGGCGGGAGC
TTTTCTAAGCGGGGGCTGGT

Product: Short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MSDSKQACVAVVTGASRGAGRGIALALGAAGATVYVTGRTEQEGSAPLPGTIHATARDIDALGGRGIAVACDHSDDAQVA
ALFQRVREEAGRLDILVNNATFLHDELIMPGPFWQKPLEMTGILDVGLRSGYVASWHAAPMMVAQGSGLIVFTSSFGANC
YMHGPAYGAQKAGIDKFAHDMAVDLRPYGVAAVSLWMGPLRTARTMQVWEKHPDKYASFAPVAETPEFTGRIVDALYRDP
ALMDKSGKVLICAEAALEYGIVDDEGVQPPSYRQVLGGPPGVHPAIVE

Sequences:

>Translated_288_residues
MSDSKQACVAVVTGASRGAGRGIALALGAAGATVYVTGRTEQEGSAPLPGTIHATARDIDALGGRGIAVACDHSDDAQVA
ALFQRVREEAGRLDILVNNATFLHDELIMPGPFWQKPLEMTGILDVGLRSGYVASWHAAPMMVAQGSGLIVFTSSFGANC
YMHGPAYGAQKAGIDKFAHDMAVDLRPYGVAAVSLWMGPLRTARTMQVWEKHPDKYASFAPVAETPEFTGRIVDALYRDP
ALMDKSGKVLICAEAALEYGIVDDEGVQPPSYRQVLGGPPGVHPAIVE
>Mature_287_residues
SDSKQACVAVVTGASRGAGRGIALALGAAGATVYVTGRTEQEGSAPLPGTIHATARDIDALGGRGIAVACDHSDDAQVAA
LFQRVREEAGRLDILVNNATFLHDELIMPGPFWQKPLEMTGILDVGLRSGYVASWHAAPMMVAQGSGLIVFTSSFGANCY
MHGPAYGAQKAGIDKFAHDMAVDLRPYGVAAVSLWMGPLRTARTMQVWEKHPDKYASFAPVAETPEFTGRIVDALYRDPA
LMDKSGKVLICAEAALEYGIVDDEGVQPPSYRQVLGGPPGVHPAIVE

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI209862901, Length=272, Percent_Identity=42.6470588235294, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI19923983, Length=272, Percent_Identity=42.6470588235294, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI40254986, Length=192, Percent_Identity=29.1666666666667, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI1787335, Length=186, Percent_Identity=31.7204301075269, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1789208, Length=207, Percent_Identity=28.0193236714976, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI87082100, Length=196, Percent_Identity=28.5714285714286, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17555612, Length=281, Percent_Identity=42.3487544483986, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI71997099, Length=284, Percent_Identity=40.4929577464789, Blast_Score=178, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI86565303, Length=290, Percent_Identity=33.448275862069, Blast_Score=128, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI71982365, Length=196, Percent_Identity=29.0816326530612, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28571526, Length=183, Percent_Identity=28.9617486338798, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357041, Length=196, Percent_Identity=29.0816326530612, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI23397609, Length=190, Percent_Identity=28.9473684210526, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 30391; Mature: 30260

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSKQACVAVVTGASRGAGRGIALALGAAGATVYVTGRTEQEGSAPLPGTIHATARDID
CCCCCCEEEEEEECCCCCCCCCEEEEEECCCEEEEEECCCCCCCCCCCCCEEEEHHHHHH
ALGGRGIAVACDHSDDAQVAALFQRVREEAGRLDILVNNATFLHDELIMPGPFWQKPLEM
HCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCEEEECCCCCCCCCCCCCCCH
TGILDVGLRSGYVASWHAAPMMVAQGSGLIVFTSSFGANCYMHGPAYGAQKAGIDKFAHD
HHEEEECCCCCEEEEECCCEEEEECCCCEEEEEECCCCEEEEECCCCCCCCCCHHHHHHH
MAVDLRPYGVAAVSLWMGPLRTARTMQVWEKHPDKYASFAPVAETPEFTGRIVDALYRDP
HEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHCCC
ALMDKSGKVLICAEAALEYGIVDDEGVQPPSYRQVLGGPPGVHPAIVE
CCCCCCCCEEEEEHHHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SDSKQACVAVVTGASRGAGRGIALALGAAGATVYVTGRTEQEGSAPLPGTIHATARDID
CCCCCEEEEEEECCCCCCCCCEEEEEECCCEEEEEECCCCCCCCCCCCCEEEEHHHHHH
ALGGRGIAVACDHSDDAQVAALFQRVREEAGRLDILVNNATFLHDELIMPGPFWQKPLEM
HCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCEEEECCCCCCCCCCCCCCCH
TGILDVGLRSGYVASWHAAPMMVAQGSGLIVFTSSFGANCYMHGPAYGAQKAGIDKFAHD
HHEEEECCCCCEEEEECCCEEEEECCCCEEEEEECCCCEEEEECCCCCCCCCCHHHHHHH
MAVDLRPYGVAAVSLWMGPLRTARTMQVWEKHPDKYASFAPVAETPEFTGRIVDALYRDP
HEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHCCC
ALMDKSGKVLICAEAALEYGIVDDEGVQPPSYRQVLGGPPGVHPAIVE
CCCCCCCCEEEEEHHHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12522265 [H]