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The map label for this gene is pcaI [H]

Identifier: 73541197

GI number: 73541197

Start: 1625113

End: 1625811

Strand: Reverse

Name: pcaI [H]

Synonym: Reut_A1506

Alternate gene names: 73541197

Gene position: 1625811-1625113 (Counterclockwise)

Preceding gene: 73541198

Following gene: 73541196

Centisome position: 42.71

GC content: 65.24

Gene sequence:

>699_bases
ATGATTGACAAGCTCTATGGGACAGCGCGCGACGCCGTGAACGATGTGCCGGACGGTGCCACCATCGCGATCGGCGGATT
CGGTGGCGCGGGCATGCCCGACGAACTGATCGATGCGCTGATCGAACACGGCGCCACGAACCTTACCGTCGTCAGCAACA
ACGCCGGCAATGGTGAAACCGGACTGGCCGCGTTGCTGAAGGCGCGCCGCGTTCGCAGGCTGGTGTGCTCCTTTCCGCGC
CAGCGCGACGCCCACGTATTTGAAGCCCTGTACCGCGCCGGGGAGATCGAACTGGAAGTCGTTCCGCAAGGCACGCTCGC
CGAACGCCTGCGCGCCGCGGGCAGCGGCATCGGCGCCTTCTACACCCCCACTGGCTATGGCACGTTGCTCGCGAAGGGCA
AGGAGACGCGCGTGATCAACGAACGCGGCTACGTGCTTGAGTACCCGATCCATGTCGACGTCGCACTGATCAACGCTGCC
GCTGCCGACCGCTGGGGCAATCTCGTCTACAACAAGACCGCACGCAACTTCGCCCCCGTGATGGCCATGGCCGCCAGCCA
GACCATTGCCGCGGTGGCACGCATCTGCGAACTAGGTGAACTGGACCCGGAAGCCGTCGTCACGCCCGGTATCTTCGTCA
GCCGCGTGGTGCTGCGCGACAGCGCTGCCATGCAGGCCAACCTCATGCACGCGAGCTGA

Upstream 100 bases:

>100_bases
TGGACTTAAGCCAGCGCTAAGGGCGCTTGCAGAAGTCGAAATTGTGAACCGCCGGGCAGCGTGGCAACCTTGTTTCGCCA
GACAACAACGAAGGCGAGAC

Downstream 100 bases:

>100_bases
AATCATGGACCAAGTCGCAAAGAACCTGCTGGCAGCGCGCGTGGCGCGCGATATCCCGAACGGATCGTACGTGAACCTCG
GCATCGGCCTGCCGACGCTG

Product: coenzyme A transferase

Products: NA

Alternate protein names: Beta-ketoadipate:succinyl-CoA transferase subunit A [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MIDKLYGTARDAVNDVPDGATIAIGGFGGAGMPDELIDALIEHGATNLTVVSNNAGNGETGLAALLKARRVRRLVCSFPR
QRDAHVFEALYRAGEIELEVVPQGTLAERLRAAGSGIGAFYTPTGYGTLLAKGKETRVINERGYVLEYPIHVDVALINAA
AADRWGNLVYNKTARNFAPVMAMAASQTIAAVARICELGELDPEAVVTPGIFVSRVVLRDSAAMQANLMHAS

Sequences:

>Translated_232_residues
MIDKLYGTARDAVNDVPDGATIAIGGFGGAGMPDELIDALIEHGATNLTVVSNNAGNGETGLAALLKARRVRRLVCSFPR
QRDAHVFEALYRAGEIELEVVPQGTLAERLRAAGSGIGAFYTPTGYGTLLAKGKETRVINERGYVLEYPIHVDVALINAA
AADRWGNLVYNKTARNFAPVMAMAASQTIAAVARICELGELDPEAVVTPGIFVSRVVLRDSAAMQANLMHAS
>Mature_232_residues
MIDKLYGTARDAVNDVPDGATIAIGGFGGAGMPDELIDALIEHGATNLTVVSNNAGNGETGLAALLKARRVRRLVCSFPR
QRDAHVFEALYRAGEIELEVVPQGTLAERLRAAGSGIGAFYTPTGYGTLLAKGKETRVINERGYVLEYPIHVDVALINAA
AADRWGNLVYNKTARNFAPVMAMAASQTIAAVARICELGELDPEAVVTPGIFVSRVVLRDSAAMQANLMHAS

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=232, Percent_Identity=43.5344827586207, Blast_Score=193, Evalue=9e-50,
Organism=Homo sapiens, GI11545841, Length=232, Percent_Identity=44.3965517241379, Blast_Score=177, Evalue=5e-45,
Organism=Escherichia coli, GI1788551, Length=219, Percent_Identity=37.8995433789954, Blast_Score=163, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17531517, Length=238, Percent_Identity=42.0168067226891, Blast_Score=176, Evalue=1e-44,
Organism=Drosophila melanogaster, GI21358325, Length=231, Percent_Identity=42.8571428571429, Blast_Score=184, Evalue=5e-47,
Organism=Drosophila melanogaster, GI24655794, Length=231, Percent_Identity=42.8571428571429, Blast_Score=184, Evalue=5e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.6 [H]

Molecular weight: Translated: 24578; Mature: 24578

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDKLYGTARDAVNDVPDGATIAIGGFGGAGMPDELIDALIEHGATNLTVVSNNAGNGET
CCCCHHCCHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCHH
GLAALLKARRVRRLVCSFPRQRDAHVFEALYRAGEIELEVVPQGTLAERLRAAGSGIGAF
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCEE
YTPTGYGTLLAKGKETRVINERGYVLEYPIHVDVALINAAAADRWGNLVYNKTARNFAPV
ECCCCCEEEEECCCCCEEECCCCCEEEECCEEEEEEHHHHHHHHHCCEEECCCHHHHHHH
MAMAASQTIAAVARICELGELDPEAVVTPGIFVSRVVLRDSAAMQANLMHAS
HHHHHHHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHCCHHHHHHCCCCC
>Mature Secondary Structure
MIDKLYGTARDAVNDVPDGATIAIGGFGGAGMPDELIDALIEHGATNLTVVSNNAGNGET
CCCCHHCCHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCHH
GLAALLKARRVRRLVCSFPRQRDAHVFEALYRAGEIELEVVPQGTLAERLRAAGSGIGAF
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCEE
YTPTGYGTLLAKGKETRVINERGYVLEYPIHVDVALINAAAADRWGNLVYNKTARNFAPV
ECCCCCEEEEECCCCCEEECCCCCEEEECCEEEEEEHHHHHHHHHCCEEECCCHHHHHHH
MAMAASQTIAAVARICELGELDPEAVVTPGIFVSRVVLRDSAAMQANLMHAS
HHHHHHHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1624453; 6780551 [H]