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The map label for this gene is qor [H]

Identifier: 73541170

GI number: 73541170

Start: 1598688

End: 1599659

Strand: Direct

Name: qor [H]

Synonym: Reut_A1476

Alternate gene names: 73541170

Gene position: 1598688-1599659 (Clockwise)

Preceding gene: 73541169

Following gene: 73541171

Centisome position: 42.0

GC content: 64.92

Gene sequence:

>972_bases
ATGCACCATGCCATCCGCATTCACGAGACCGGTGGACCCGAAAAGCTTGTCTGGGATCAGATTTCCGTCGACGATCCCGG
CCCAGGGCAAGCGCGCCTTCGCCAGACGGCCGTCGGCGTGAACTTCATCGACATCTACTTCCGCACCGGCCTCTACCCGT
TGCCGCTGCCGTTTATCCCGGGGCGCGAAGCGGTCGGCGTAGTCGAGGCAGTCGGGCCTGACGTCACTTCGCTGAAGCCG
GGCGACCGTGTCGTATATAGCGGCGTGCAGGGCGCCTACGCCCAGGTCCGGCTGGTGCCGGCCGATCGCCTGGTCAAACT
TCCCGACGGCATCAGCGACGAGATCGGTGCGGCGGTGATGCAGAAGGGCATGACCGCGCAGTTCCTGTGCCGTCAGACCT
ACCAAGTCGGCAAGGACGACACGATCCTCGTGCACGCGGCCGCAGGCGGCGTCGGCCTCGTGCTGTGCCAGTGGGCCAAG
CATCTGGGTGCGACCGTCATCGGCACCGTGTCGACTGAGGAAAAGGCGAAGCTTGTGGAGGCCCACGGCTGCGACCATGC
GCTGATCCACGGCAAGGACGACTTCGTCGAGGTAGTGAAGGAGATCACAGGCGGCGTCGGTGTCCCAGTCGTCTATGACT
CGATCGGTAAGGATACCTTCATGGGCTCGCTCGACTGCCTCAGGCCGCGCGGCCTGATGGTGCTCTACGGCCAGTCCTCC
GGCCCGGTGCCGCCGTTCGACATCAGCATCCTCGACAAGAAGGGCTCGCTGTTCCTGACCCGCCCGACCCAGAATGCGTA
CCTGCCCACCCGCGCCAAGGTCGAGGAGGGTGCGCAGGAGGTGTTCGACGTCGTGCAGTCAGGGGCGGTGAAGGTTCACA
TCAACCAGCGCTTCGCGCTCAAGGACGCGGCTGAAGCGCATCTTGCGATGGAGTCGCGCAAGACGACCGGTTCTCTGGTG
CTGCTGCCCTGA

Upstream 100 bases:

>100_bases
GCCCAGGACAGATGAGCCCGCCGGCCGGAGTACAGCCATACCGCCGACGTACCTGCACTAACCCAATCTGCAAAATTTAG
TCAACAGAAGGAGACGACTG

Downstream 100 bases:

>100_bases
AGCGAAGCGCCGTCGGCGTCTCGAAGCCGGCATTGCTTTTCAGAATGATCTTTACCCTGCCCGGGGCGGACAGTCCCGGG
CAACGTTTTGCTTCACGATG

Product: zinc-containing alcohol dehydrogenase superfamily protein

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MHHAIRIHETGGPEKLVWDQISVDDPGPGQARLRQTAVGVNFIDIYFRTGLYPLPLPFIPGREAVGVVEAVGPDVTSLKP
GDRVVYSGVQGAYAQVRLVPADRLVKLPDGISDEIGAAVMQKGMTAQFLCRQTYQVGKDDTILVHAAAGGVGLVLCQWAK
HLGATVIGTVSTEEKAKLVEAHGCDHALIHGKDDFVEVVKEITGGVGVPVVYDSIGKDTFMGSLDCLRPRGLMVLYGQSS
GPVPPFDISILDKKGSLFLTRPTQNAYLPTRAKVEEGAQEVFDVVQSGAVKVHINQRFALKDAAEAHLAMESRKTTGSLV
LLP

Sequences:

>Translated_323_residues
MHHAIRIHETGGPEKLVWDQISVDDPGPGQARLRQTAVGVNFIDIYFRTGLYPLPLPFIPGREAVGVVEAVGPDVTSLKP
GDRVVYSGVQGAYAQVRLVPADRLVKLPDGISDEIGAAVMQKGMTAQFLCRQTYQVGKDDTILVHAAAGGVGLVLCQWAK
HLGATVIGTVSTEEKAKLVEAHGCDHALIHGKDDFVEVVKEITGGVGVPVVYDSIGKDTFMGSLDCLRPRGLMVLYGQSS
GPVPPFDISILDKKGSLFLTRPTQNAYLPTRAKVEEGAQEVFDVVQSGAVKVHINQRFALKDAAEAHLAMESRKTTGSLV
LLP
>Mature_323_residues
MHHAIRIHETGGPEKLVWDQISVDDPGPGQARLRQTAVGVNFIDIYFRTGLYPLPLPFIPGREAVGVVEAVGPDVTSLKP
GDRVVYSGVQGAYAQVRLVPADRLVKLPDGISDEIGAAVMQKGMTAQFLCRQTYQVGKDDTILVHAAAGGVGLVLCQWAK
HLGATVIGTVSTEEKAKLVEAHGCDHALIHGKDDFVEVVKEITGGVGVPVVYDSIGKDTFMGSLDCLRPRGLMVLYGQSS
GPVPPFDISILDKKGSLFLTRPTQNAYLPTRAKVEEGAQEVFDVVQSGAVKVHINQRFALKDAAEAHLAMESRKTTGSLV
LLP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=331, Percent_Identity=30.2114803625378, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI13236495, Length=331, Percent_Identity=30.2114803625378, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI194239676, Length=205, Percent_Identity=36.0975609756098, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI22538446, Length=335, Percent_Identity=29.8507462686567, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI22538444, Length=335, Percent_Identity=29.8507462686567, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI18379349, Length=319, Percent_Identity=28.5266457680251, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI24308257, Length=241, Percent_Identity=32.3651452282158, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI28557745, Length=234, Percent_Identity=31.1965811965812, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI197927207, Length=187, Percent_Identity=26.2032085561497, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1790485, Length=327, Percent_Identity=47.0948012232416, Blast_Score=292, Evalue=2e-80,
Organism=Escherichia coli, GI87081918, Length=266, Percent_Identity=28.9473684210526, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17507255, Length=213, Percent_Identity=32.3943661971831, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71987554, Length=209, Percent_Identity=30.622009569378, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=324, Percent_Identity=36.4197530864198, Blast_Score=196, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6323729, Length=253, Percent_Identity=27.6679841897233, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34607; Mature: 34607

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHHAIRIHETGGPEKLVWDQISVDDPGPGQARLRQTAVGVNFIDIYFRTGLYPLPLPFIP
CCCEEEEECCCCCCEEEEEEECCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCC
GREAVGVVEAVGPDVTSLKPGDRVVYSGVQGAYAQVRLVPADRLVKLPDGISDEIGAAVM
CCHHHHHHHHCCCCCCCCCCCCEEEECCCCCCEEEEEEECHHHEEECCCCCCHHHHHHHH
QKGMTAQFLCRQTYQVGKDDTILVHAAAGGVGLVLCQWAKHLGATVIGTVSTEEKAKLVE
HCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHH
AHGCDHALIHGKDDFVEVVKEITGGVGVPVVYDSIGKDTFMGSLDCLRPRGLMVLYGQSS
HCCCCEEEEECCHHHHHHHHHHHCCCCCCEEECCCCCCHHCCCHHHCCCCCEEEEEECCC
GPVPPFDISILDKKGSLFLTRPTQNAYLPTRAKVEEGAQEVFDVVQSGAVKVHINQRFAL
CCCCCCEEEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCEEEH
KDAAEAHLAMESRKTTGSLVLLP
HHHHHHHHHHHCCCCCCCEEEEC
>Mature Secondary Structure
MHHAIRIHETGGPEKLVWDQISVDDPGPGQARLRQTAVGVNFIDIYFRTGLYPLPLPFIP
CCCEEEEECCCCCCEEEEEEECCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCC
GREAVGVVEAVGPDVTSLKPGDRVVYSGVQGAYAQVRLVPADRLVKLPDGISDEIGAAVM
CCHHHHHHHHCCCCCCCCCCCCEEEECCCCCCEEEEEEECHHHEEECCCCCCHHHHHHHH
QKGMTAQFLCRQTYQVGKDDTILVHAAAGGVGLVLCQWAKHLGATVIGTVSTEEKAKLVE
HCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHH
AHGCDHALIHGKDDFVEVVKEITGGVGVPVVYDSIGKDTFMGSLDCLRPRGLMVLYGQSS
HCCCCEEEEECCHHHHHHHHHHHCCCCCCEEECCCCCCHHCCCHHHCCCCCEEEEEECCC
GPVPPFDISILDKKGSLFLTRPTQNAYLPTRAKVEEGAQEVFDVVQSGAVKVHINQRFAL
CCCCCCEEEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCEEEH
KDAAEAHLAMESRKTTGSLVLLP
HHHHHHHHHHHCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]