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The map label for this gene is tauC [H]

Identifier: 73541164

GI number: 73541164

Start: 1590678

End: 1591583

Strand: Reverse

Name: tauC [H]

Synonym: Reut_A1470

Alternate gene names: 73541164

Gene position: 1591583-1590678 (Counterclockwise)

Preceding gene: 73541165

Following gene: 73541163

Centisome position: 41.81

GC content: 68.43

Gene sequence:

>906_bases
ATGACCGTACCCGCCCAACAGGTCGACGCTGCCGCCGTGGCAGCCCCCGCCGTCCCGACCCGGAGCACGGCTCCGGCCGG
CCAGCCCGCCGCACCGCGCCGCGCCATGCGCACCGTCTCCGGTTACCGCATGCCGGGCGAAGGCTCCAGCTCGCGCATCG
CCACCGTCACGGTAATGACGCTGCTGGCGCTGTGGTGGATCGCCAGCCACCTGCAGTGGCTGCCGCCGCTGTTCCTGCCC
ACGCCGGAGGCCATCATCCGGGCCTTTATCGATGCCTGGAACGGCAATGTGCAAGGCGGCCTGCCGTTGCTGGACCACTT
CCACGCCAGCCTGGTGCGCGTCTTCGGCGCCTTCGCGCTGGCCGTGCTCACCGCGGTGCCGATCGGCGTGCTGATGGGCG
TGTCGCGCGTCGCGCGCGGCGTCTTCGATCCGCCAATCGAGTTCTACCGTCCGCTGCCGCCGCTGGCCTACCTGCCGCTG
ATCGTGATCTGGTTCGGCATCGACGAGACCTCCAAGATCCTGCTGATCTACCTGGCCTGCTTCGCGCCGCTGGCCATGTC
AGCGCGCGCCGGCGTGCGTTCGGTCACGATCGAGCAGATCAATGCGGCCTACTCGATGGGTGCCACGCCGTGGCAGGTGA
TCCGCCATGTGGTGCTGCCCGCTGCGCTGCCCGACATCCTGACCGGCATGCGCATCGCCATCGGCTTCGGCTGGACCACG
CTGGTCGCCGCCGAGATGGTCGCAGCGACCGCCGGACTCGGCCAGATGGTGCTCAATGCGTCCAACTTCCTGCGCACCGA
CGTGGTGATCATGGGCATCCTGCTGATCGGGCTGATCGCCTTCCTGTTCGACCTGCTGATGCGCAAGTCGGAAACGTGGC
TGGTGCCCTGGAAGGGCCGTATGTAA

Upstream 100 bases:

>100_bases
GAATGCGGCGACGCGCGCGCCGTCAAGTCCGATCCGGAATTTATCCGCTATCGCGAAGAAATCGTCGACCTGATCCATGC
CACGCCCTGAGGACAAAGCC

Downstream 100 bases:

>100_bases
GACGACACCCGGCTCCGTCGGCAGGAGCACGAAGCGCCCGCCTGTGCCGCAGCCGCGGCCCGGGCGGGCGCTTTGCATTG
GTGCAGCGGACGATGGCAGA

Product: binding-protein dependent transport system inner membrane protein

Products: taurine [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MTVPAQQVDAAAVAAPAVPTRSTAPAGQPAAPRRAMRTVSGYRMPGEGSSSRIATVTVMTLLALWWIASHLQWLPPLFLP
TPEAIIRAFIDAWNGNVQGGLPLLDHFHASLVRVFGAFALAVLTAVPIGVLMGVSRVARGVFDPPIEFYRPLPPLAYLPL
IVIWFGIDETSKILLIYLACFAPLAMSARAGVRSVTIEQINAAYSMGATPWQVIRHVVLPAALPDILTGMRIAIGFGWTT
LVAAEMVAATAGLGQMVLNASNFLRTDVVIMGILLIGLIAFLFDLLMRKSETWLVPWKGRM

Sequences:

>Translated_301_residues
MTVPAQQVDAAAVAAPAVPTRSTAPAGQPAAPRRAMRTVSGYRMPGEGSSSRIATVTVMTLLALWWIASHLQWLPPLFLP
TPEAIIRAFIDAWNGNVQGGLPLLDHFHASLVRVFGAFALAVLTAVPIGVLMGVSRVARGVFDPPIEFYRPLPPLAYLPL
IVIWFGIDETSKILLIYLACFAPLAMSARAGVRSVTIEQINAAYSMGATPWQVIRHVVLPAALPDILTGMRIAIGFGWTT
LVAAEMVAATAGLGQMVLNASNFLRTDVVIMGILLIGLIAFLFDLLMRKSETWLVPWKGRM
>Mature_300_residues
TVPAQQVDAAAVAAPAVPTRSTAPAGQPAAPRRAMRTVSGYRMPGEGSSSRIATVTVMTLLALWWIASHLQWLPPLFLPT
PEAIIRAFIDAWNGNVQGGLPLLDHFHASLVRVFGAFALAVLTAVPIGVLMGVSRVARGVFDPPIEFYRPLPPLAYLPLI
VIWFGIDETSKILLIYLACFAPLAMSARAGVRSVTIEQINAAYSMGATPWQVIRHVVLPAALPDILTGMRIAIGFGWTTL
VAAEMVAATAGLGQMVLNASNFLRTDVVIMGILLIGLIAFLFDLLMRKSETWLVPWKGRM

Specific function: Part of a binding-protein-dependent transport system for taurine. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0600

COG function: function code P; ABC-type nitrate/sulfonate/bicarbonate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786564, Length=254, Percent_Identity=52.755905511811, Blast_Score=231, Evalue=7e-62,
Organism=Escherichia coli, GI87081802, Length=225, Percent_Identity=35.5555555555556, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1789033, Length=169, Percent_Identity=27.810650887574, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32417; Mature: 32286

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVPAQQVDAAAVAAPAVPTRSTAPAGQPAAPRRAMRTVSGYRMPGEGSSSRIATVTVMT
CCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
LLALWWIASHLQWLPPLFLPTPEAIIRAFIDAWNGNVQGGLPLLDHFHASLVRVFGAFAL
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
AVLTAVPIGVLMGVSRVARGVFDPPIEFYRPLPPLAYLPLIVIWFGIDETSKILLIYLAC
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
FAPLAMSARAGVRSVTIEQINAAYSMGATPWQVIRHVVLPAALPDILTGMRIAIGFGWTT
HHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LVAAEMVAATAGLGQMVLNASNFLRTDVVIMGILLIGLIAFLFDLLMRKSETWLVPWKGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCC
M
C
>Mature Secondary Structure 
TVPAQQVDAAAVAAPAVPTRSTAPAGQPAAPRRAMRTVSGYRMPGEGSSSRIATVTVMT
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHH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C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: taurine [Periplasm]; ATP; H2O [C]

Specific reaction: taurine [Periplasm] + ATP + H2O = taurine [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8808933; 9278503 [H]