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The map label for this gene is ppiD [H]

Identifier: 73541077

GI number: 73541077

Start: 1493170

End: 1495119

Strand: Direct

Name: ppiD [H]

Synonym: Reut_A1383

Alternate gene names: 73541077

Gene position: 1493170-1495119 (Clockwise)

Preceding gene: 73541076

Following gene: 73541079

Centisome position: 39.23

GC content: 63.38

Gene sequence:

>1950_bases
ATGCTTGATTTCGTACGCAATAACCGGCGCTTGATGCTTTTGCTGCTGCTGGTGCTTGTCTTTCCGTCGTTCGTGTTCTT
CGGCGTGGAGAGCTACTCGCGCTTCATGGACAGCTCGCACGATGTCGCGAAGGTCGACGGCCGCGCGATCACGGTGCAGG
AAGTGGACAACGTGGTGCGTGAACAAAGCGAGCGCATGCGCCAGATGCTTGGCGCCAGCTACGATCCGCGCCAGTTCGAG
GGCCCGATGCTGCGCAAAAACGTGACGGATCAGCTGATCCTGCAACGCGTGGTGGCCAATGAGGTGGCGCGCGAACACCT
GACGGTGTCGAACGCACGCCTGTACGAGGCAATCAATAGCATTCCGGCGATTGCGCAACTGCCGCGCAAGCAGGACGGTT
CGGTCGACGACAAGGCCTATGTGCAACTGCTGGCGGCGCAAGGCATGACGCCGGAGCAGTTCGATGCGCGCATGCGCTTT
GACCTCGCCACGCAGCAACTGGGCACTTCGATCGCCGGCACGGCCTTCGTGCCCAAGTCTCTGCTGGACCGCCTGATTGC
CGTGCGCGACCAGCAGCGCGACGTTCAGGCCCTGTTGTTCAAGCCGGCCGACTACGCATCCAAGGTGCAGCCTGATGCCG
CCGCGCTCAAGGCGTACTACGAGAGCCACCAGTCCGCGTTCTCCGTGCCCGAGCAGGCCAAGGTGGAATACGTCGTGCTG
TCCGGCGATGCACTGGCAGCAAGCCAGGCCGTCAGTCCCGAGGAACTGAAGTCCTACTACGACAGCAATATCGCGCGCTT
CCGCACGGAAGAGCAGCGCCGCGCGAGCCATATCCTGATCGCGGCACCCAAGGATGGCCCGGCGGCGGCGCGTCAGGCGG
CCAAGGACAAGGCCGGCAAGCTGCTGGAAGAGCTGCGCAAGCACCCCGATACATTTGCCGACGTGGCGCGCAAGCAGTCG
CAGGATCCGGGTTCGGCGGAGAAGGGCGGTGATCTCGGCTTCATGGGCCATGGCGCACTGGTCAAGCCGTTCGAAGATGC
GATGTACGCGCTCAAGGACGGCCAGATCAGCGATGTGGTCGAGACCGACTACGGCTACCACATCATCAAGCTGACGGGCA
TCAAGCCGTCCGAAACCAAACCGCTGGACGCCGTGCGGCCCGAGCTTGAGGCCGAGCTGCGCAAGCAGTTCGCCGCCAAG
AAGTACGCCGAAGATGCCGATGCCTTCGGCAACATGGTGTACGAGCAAGCAGATAGCCTGAAGCCTGCTGCCGACAAGTT
CAAGCTGACGATCCAGACCGCGGACAACGTGACGCGCCAGCCGAATCCGGCGCTGGGCCAAAACAATCCGCTCAACAATG
AGAAGGTCCTCAAGGCGCTATTCAGCGATGACGCCATCAAGAACAAGCGCAACACGGAGGCTGTTCAGGTCGGTCCGACC
ACGCTGGTTGCGGCGCGCATCGTGGACTACCGCCCGGCGACCGTGCGCAAGTTCGAGGAAGTCGAGGCCAAGGTCCGCGA
AGGCTATATCGCCCAGCAGGCCGCGGAGCTCGCTCGCAAGGATGGCGAGGCACGCGTGGAAGCCCTGAAGAAGAGCGACA
GCGCGCAAGGCTTCGGCGCCGTCACGATGGTGTCGCGTGCCAAGGCTGAAGGCATGGAACCCAAGGCCGTGGAAGCCATC
ATGCGGGCCGATACCTCGAAGCTGCCCGCGGTGGTGGGTGTGGATCTGGGTGCGAACGGCTATGCGGTCTATCGCATCAC
CAAGATTTCGCAGCCGCAGCAGGCCAATGAGGGCCAGCGCCAGGCAGAGGCGCAACAGCTCTCGCAACTGGCCGGCCAGA
CCGAGCTTGGTGCGTACTACGAGAGCCTGAAGGCGCGGTCGAAGGTCAAGATCCTGAAGCCGGTTGCCACGGCGGACACC
GGCGCCGGCAGCGAAGCGGCTGCGCAATAG

Upstream 100 bases:

>100_bases
TCTCCGGCGCGGCCCTTGGCCGCCAAATGGCTGTGCAGCGCCCGGCTCCTGCTAGAATCGCGGAGTTTGACTTCGTGCCA
ACCCTCTTACCCGAGTCCGC

Downstream 100 bases:

>100_bases
CGCTTAGTGCAATGACAAAGCCCCCTGCGAATTCCGCAGGGGGCTTTTTCTTTGTGTTGTTGGTGGCCAGAGGTGCCGTC
AGCCTTTGCCGCCGGCCCTG

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 649; Mature: 649

Protein sequence:

>649_residues
MLDFVRNNRRLMLLLLLVLVFPSFVFFGVESYSRFMDSSHDVAKVDGRAITVQEVDNVVREQSERMRQMLGASYDPRQFE
GPMLRKNVTDQLILQRVVANEVAREHLTVSNARLYEAINSIPAIAQLPRKQDGSVDDKAYVQLLAAQGMTPEQFDARMRF
DLATQQLGTSIAGTAFVPKSLLDRLIAVRDQQRDVQALLFKPADYASKVQPDAAALKAYYESHQSAFSVPEQAKVEYVVL
SGDALAASQAVSPEELKSYYDSNIARFRTEEQRRASHILIAAPKDGPAAARQAAKDKAGKLLEELRKHPDTFADVARKQS
QDPGSAEKGGDLGFMGHGALVKPFEDAMYALKDGQISDVVETDYGYHIIKLTGIKPSETKPLDAVRPELEAELRKQFAAK
KYAEDADAFGNMVYEQADSLKPAADKFKLTIQTADNVTRQPNPALGQNNPLNNEKVLKALFSDDAIKNKRNTEAVQVGPT
TLVAARIVDYRPATVRKFEEVEAKVREGYIAQQAAELARKDGEARVEALKKSDSAQGFGAVTMVSRAKAEGMEPKAVEAI
MRADTSKLPAVVGVDLGANGYAVYRITKISQPQQANEGQRQAEAQQLSQLAGQTELGAYYESLKARSKVKILKPVATADT
GAGSEAAAQ

Sequences:

>Translated_649_residues
MLDFVRNNRRLMLLLLLVLVFPSFVFFGVESYSRFMDSSHDVAKVDGRAITVQEVDNVVREQSERMRQMLGASYDPRQFE
GPMLRKNVTDQLILQRVVANEVAREHLTVSNARLYEAINSIPAIAQLPRKQDGSVDDKAYVQLLAAQGMTPEQFDARMRF
DLATQQLGTSIAGTAFVPKSLLDRLIAVRDQQRDVQALLFKPADYASKVQPDAAALKAYYESHQSAFSVPEQAKVEYVVL
SGDALAASQAVSPEELKSYYDSNIARFRTEEQRRASHILIAAPKDGPAAARQAAKDKAGKLLEELRKHPDTFADVARKQS
QDPGSAEKGGDLGFMGHGALVKPFEDAMYALKDGQISDVVETDYGYHIIKLTGIKPSETKPLDAVRPELEAELRKQFAAK
KYAEDADAFGNMVYEQADSLKPAADKFKLTIQTADNVTRQPNPALGQNNPLNNEKVLKALFSDDAIKNKRNTEAVQVGPT
TLVAARIVDYRPATVRKFEEVEAKVREGYIAQQAAELARKDGEARVEALKKSDSAQGFGAVTMVSRAKAEGMEPKAVEAI
MRADTSKLPAVVGVDLGANGYAVYRITKISQPQQANEGQRQAEAQQLSQLAGQTELGAYYESLKARSKVKILKPVATADT
GAGSEAAAQ
>Mature_649_residues
MLDFVRNNRRLMLLLLLVLVFPSFVFFGVESYSRFMDSSHDVAKVDGRAITVQEVDNVVREQSERMRQMLGASYDPRQFE
GPMLRKNVTDQLILQRVVANEVAREHLTVSNARLYEAINSIPAIAQLPRKQDGSVDDKAYVQLLAAQGMTPEQFDARMRF
DLATQQLGTSIAGTAFVPKSLLDRLIAVRDQQRDVQALLFKPADYASKVQPDAAALKAYYESHQSAFSVPEQAKVEYVVL
SGDALAASQAVSPEELKSYYDSNIARFRTEEQRRASHILIAAPKDGPAAARQAAKDKAGKLLEELRKHPDTFADVARKQS
QDPGSAEKGGDLGFMGHGALVKPFEDAMYALKDGQISDVVETDYGYHIIKLTGIKPSETKPLDAVRPELEAELRKQFAAK
KYAEDADAFGNMVYEQADSLKPAADKFKLTIQTADNVTRQPNPALGQNNPLNNEKVLKALFSDDAIKNKRNTEAVQVGPT
TLVAARIVDYRPATVRKFEEVEAKVREGYIAQQAAELARKDGEARVEALKKSDSAQGFGAVTMVSRAKAEGMEPKAVEAI
MRADTSKLPAVVGVDLGANGYAVYRITKISQPQQANEGQRQAEAQQLSQLAGQTELGAYYESLKARSKVKILKPVATADT
GAGSEAAAQ

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=652, Percent_Identity=27.4539877300614, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1786238, Length=136, Percent_Identity=30.1470588235294, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 71185; Mature: 71185

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDFVRNNRRLMLLLLLVLVFPSFVFFGVESYSRFMDSSHDVAKVDGRAITVQEVDNVVR
CCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEHHHHHHHHH
EQSERMRQMLGASYDPRQFEGPMLRKNVTDQLILQRVVANEVAREHLTVSNARLYEAINS
HHHHHHHHHHCCCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IPAIAQLPRKQDGSVDDKAYVQLLAAQGMTPEQFDARMRFDLATQQLGTSIAGTAFVPKS
CHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LLDRLIAVRDQQRDVQALLFKPADYASKVQPDAAALKAYYESHQSAFSVPEQAKVEYVVL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
SGDALAASQAVSPEELKSYYDSNIARFRTEEQRRASHILIAAPKDGPAAARQAAKDKAGK
ECCHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHH
LLEELRKHPDTFADVARKQSQDPGSAEKGGDLGFMGHGALVKPFEDAMYALKDGQISDVV
HHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHCCCCHHHHH
ETDYGYHIIKLTGIKPSETKPLDAVRPELEAELRKQFAAKKYAEDADAFGNMVYEQADSL
HCCCCEEEEEEECCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KPAADKFKLTIQTADNVTRQPNPALGQNNPLNNEKVLKALFSDDAIKNKRNTEAVQVGPT
CCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCH
TLVAARIVDYRPATVRKFEEVEAKVREGYIAQQAAELARKDGEARVEALKKSDSAQGFGA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHH
VTMVSRAKAEGMEPKAVEAIMRADTSKLPAVVGVDLGANGYAVYRITKISQPQQANEGQR
HHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEEECCCCCCCCHHHH
QAEAQQLSQLAGQTELGAYYESLKARSKVKILKPVATADTGAGSEAAAQ
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCHHCCC
>Mature Secondary Structure
MLDFVRNNRRLMLLLLLVLVFPSFVFFGVESYSRFMDSSHDVAKVDGRAITVQEVDNVVR
CCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEHHHHHHHHH
EQSERMRQMLGASYDPRQFEGPMLRKNVTDQLILQRVVANEVAREHLTVSNARLYEAINS
HHHHHHHHHHCCCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IPAIAQLPRKQDGSVDDKAYVQLLAAQGMTPEQFDARMRFDLATQQLGTSIAGTAFVPKS
CHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LLDRLIAVRDQQRDVQALLFKPADYASKVQPDAAALKAYYESHQSAFSVPEQAKVEYVVL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
SGDALAASQAVSPEELKSYYDSNIARFRTEEQRRASHILIAAPKDGPAAARQAAKDKAGK
ECCHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHH
LLEELRKHPDTFADVARKQSQDPGSAEKGGDLGFMGHGALVKPFEDAMYALKDGQISDVV
HHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHCCCCHHHHH
ETDYGYHIIKLTGIKPSETKPLDAVRPELEAELRKQFAAKKYAEDADAFGNMVYEQADSL
HCCCCEEEEEEECCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KPAADKFKLTIQTADNVTRQPNPALGQNNPLNNEKVLKALFSDDAIKNKRNTEAVQVGPT
CCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCH
TLVAARIVDYRPATVRKFEEVEAKVREGYIAQQAAELARKDGEARVEALKKSDSAQGFGA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHH
VTMVSRAKAEGMEPKAVEAIMRADTSKLPAVVGVDLGANGYAVYRITKISQPQQANEGQR
HHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEEECCCCCCCCHHHH
QAEAQQLSQLAGQTELGAYYESLKARSKVKILKPVATADTGAGSEAAAQ
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]