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The map label for this gene is uppP

Identifier: 73540461

GI number: 73540461

Start: 819606

End: 820487

Strand: Direct

Name: uppP

Synonym: Reut_A0757

Alternate gene names: 73540461

Gene position: 819606-820487 (Clockwise)

Preceding gene: 73540460

Following gene: 73540464

Centisome position: 21.53

GC content: 63.27

Gene sequence:

>882_bases
ATGGAAATCGCACTTGCCCTGAAAGCCGTGATCCTCGGCATCGTCGAAGGACTGACCGAGTTTCTGCCCATTTCGAGCAC
CGGCCACCTGATCCTGGCCGGCCAGCTGCTCGACTTCAACGACGAGAAGGGCAAGATCTTCGAGATCGTGATCCAGTTCG
GCGCGATTCTGGCGGTGTGCTGGGAGTTTCGCCGGCGCATCGCCAACGTGCTAAGCGGGTTGACGACCGACCCGAAAGCG
CAGCGCTTTGCCATCAACGTGATCGTGGCGACGGTGCCGGCCATCGTGCTGGCGCTGGTGTTCGGCAAATGGATCAAGGC
CCATCTGTTCAACCCGATCACGGTGGCGCTGGCCTTCATCATTGGCGGCGTGGTAATCCTGCTCGCGGAACGGCGCGACG
CGCGCCGCGGCATGGTGACCAACCCGCGCGGCAATGCCTTGCTGCAAGCCGCCAAGGCGGGCGCACCGCGCATCGAGTCG
GTCGATGACCTGAACTGGCGCGATGCGCTGAAGGTCGGCCTCGCCCAGTGCTTTGCGCTGGTGCCAGGCACGTCACGGTC
GGGCGCGACCATCATCGGCGGCATGCTGTTCGGCCTGTCGCGTCAGGTCGCGACCGAGTTCTCGTTCTTCCTGGCCATCC
CTGTGATCTTCGGCGCGACGGTGTACGAGCTCTACAAGGCCCGCGCCCTGCTGTCCGTCGATGATCTCGGCATCTTCGGC
ATTGGTTTCGTTTTCGCGTTTCTGTCGGCCTTCCTCTGCGTACGCTGGCTCCTGCGCTTTGTCGCGACGCATGACTTCAA
GCCGTTCGCGTGGTACCGGATCGCATTCGGCATCATCGTGCTGGCGACGGCGTACTCGGGATTGATTGCCTGGCACGCCT
GA

Upstream 100 bases:

>100_bases
GTCCGACGGCATCAACGTCAAGATCAATCGCCCCTGAGCCAAAAAACAGACATCGGCCCGTCAATATCGGGCATGTCCCC
GCCCAACCCATCCCATCCGC

Downstream 100 bases:

>100_bases
TCCGTCAGGCTGAATGCAAAAAAGGCGTGGCCACCATGTGCCACGCCTTTTTTTGCTTGGGCTGCTTGTGTCGGGTTGCG
CCGATCAACCGCGCTTGCGG

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MEIALALKAVILGIVEGLTEFLPISSTGHLILAGQLLDFNDEKGKIFEIVIQFGAILAVCWEFRRRIANVLSGLTTDPKA
QRFAINVIVATVPAIVLALVFGKWIKAHLFNPITVALAFIIGGVVILLAERRDARRGMVTNPRGNALLQAAKAGAPRIES
VDDLNWRDALKVGLAQCFALVPGTSRSGATIIGGMLFGLSRQVATEFSFFLAIPVIFGATVYELYKARALLSVDDLGIFG
IGFVFAFLSAFLCVRWLLRFVATHDFKPFAWYRIAFGIIVLATAYSGLIAWHA

Sequences:

>Translated_293_residues
MEIALALKAVILGIVEGLTEFLPISSTGHLILAGQLLDFNDEKGKIFEIVIQFGAILAVCWEFRRRIANVLSGLTTDPKA
QRFAINVIVATVPAIVLALVFGKWIKAHLFNPITVALAFIIGGVVILLAERRDARRGMVTNPRGNALLQAAKAGAPRIES
VDDLNWRDALKVGLAQCFALVPGTSRSGATIIGGMLFGLSRQVATEFSFFLAIPVIFGATVYELYKARALLSVDDLGIFG
IGFVFAFLSAFLCVRWLLRFVATHDFKPFAWYRIAFGIIVLATAYSGLIAWHA
>Mature_293_residues
MEIALALKAVILGIVEGLTEFLPISSTGHLILAGQLLDFNDEKGKIFEIVIQFGAILAVCWEFRRRIANVLSGLTTDPKA
QRFAINVIVATVPAIVLALVFGKWIKAHLFNPITVALAFIIGGVVILLAERRDARRGMVTNPRGNALLQAAKAGAPRIES
VDDLNWRDALKVGLAQCFALVPGTSRSGATIIGGMLFGLSRQVATEFSFFLAIPVIFGATVYELYKARALLSVDDLGIFG
IGFVFAFLSAFLCVRWLLRFVATHDFKPFAWYRIAFGIIVLATAYSGLIAWHA

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=274, Percent_Identity=42.7007299270073, Blast_Score=209, Evalue=2e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_CUPPJ (Q474P6)

Other databases:

- EMBL:   CP000090
- RefSeq:   YP_294981.1
- GeneID:   3609917
- GenomeReviews:   CP000090_GR
- KEGG:   reu:Reut_A0757
- NMPDR:   fig|264198.3.peg.1271
- HOGENOM:   HBG391969
- OMA:   PERENVT
- ProtClustDB:   PRK00281
- BioCyc:   REUT264198:REUT_A0757-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 31881; Mature: 31881

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe8f14d4)-; HASH(0xe828c04)-; HASH(0xe6081f8)-; HASH(0xefc2950)-; HASH(0xf0a7518)-; HASH(0xf24c4cc)-; HASH(0xce4ff9c)-; HASH(0xe9ab1fc)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIALALKAVILGIVEGLTEFLPISSTGHLILAGQLLDFNDEKGKIFEIVIQFGAILAVC
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHH
WEFRRRIANVLSGLTTDPKAQRFAINVIVATVPAIVLALVFGKWIKAHLFNPITVALAFI
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
IGGVVILLAERRDARRGMVTNPRGNALLQAAKAGAPRIESVDDLNWRDALKVGLAQCFAL
HHHHHHHHHCCHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
VPGTSRSGATIIGGMLFGLSRQVATEFSFFLAIPVIFGATVYELYKARALLSVDDLGIFG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCHHHH
IGFVFAFLSAFLCVRWLLRFVATHDFKPFAWYRIAFGIIVLATAYSGLIAWHA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEECH
>Mature Secondary Structure
MEIALALKAVILGIVEGLTEFLPISSTGHLILAGQLLDFNDEKGKIFEIVIQFGAILAVC
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHH
WEFRRRIANVLSGLTTDPKAQRFAINVIVATVPAIVLALVFGKWIKAHLFNPITVALAFI
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
IGGVVILLAERRDARRGMVTNPRGNALLQAAKAGAPRIESVDDLNWRDALKVGLAQCFAL
HHHHHHHHHCCHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
VPGTSRSGATIIGGMLFGLSRQVATEFSFFLAIPVIFGATVYELYKARALLSVDDLGIFG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCHHHH
IGFVFAFLSAFLCVRWLLRFVATHDFKPFAWYRIAFGIIVLATAYSGLIAWHA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEECH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA