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The map label for this gene is sigK [H]

Identifier: 73540403

GI number: 73540403

Start: 754596

End: 755279

Strand: Reverse

Name: sigK [H]

Synonym: Reut_A0697

Alternate gene names: 73540403

Gene position: 755279-754596 (Counterclockwise)

Preceding gene: 73540405

Following gene: 73540402

Centisome position: 19.84

GC content: 68.42

Gene sequence:

>684_bases
ATGCTGCTTTTACGCAGGCACCGGGCAATTGGATGCAGCGACGCTGCCTATAATCCGTCAGAGCCCTCCGCCAGGAACCT
CCACGTGCCGGCTGCCCCCGAACCATCGTTTGCCCCATCGGCCGACAACGACCGGCTGGCGGCGTGGCTGCAGGCGGTGG
CGCTCGGCGACCGGCAGGCGCTGCGCGCGCTCTACGACCACACCGCGACGAAACTGTTCGGCCTTGCGCTGCGTATCACT
GGAAGGCGCGACTGGGCGGAGGACGCCGTGCAGGAAAGCTTTGTCAGCATCTGGCACCACGCCGGCGACTACCGGCCGCA
CCTGGCCGCGCCGATGACGTGGATGACCACCATCGTTCGCAATCGCGCGCTCGACTGCCTGCGCCGCGCGGCAGCCGCGC
GCGTACCGCAGACCGTGGAACTCGATGAAGAACTCGGCGAATGGCTGGCCGACGATGCTGCCGGCCCGGCTGAACTGGCG
CTGGCCAGCCAGCAGGCGCGCGCACTGAACCGCTGCCTGCAACGGCTGGAGCCGGCACAGCGGCAAGCCATCGTCCTGGC
CTACTTGCGCGACCTGAGCCACGCCGAACTGTCCGAGCGGCTGCGATTGCCGCTTGGCACCGTGAAGTCGTGGATCCGTC
GAGGTCTCGAACGCCTGCGCGCGTGCCTGGAGAGTGCGCCATGA

Upstream 100 bases:

>100_bases
TTTCTCGGACTGAACCAGCCGGTGCGCCGGCGTCGTGGACATGCGTTCCATGGTGTGCTCCTGTGAGAGATCAAGGGACA
GCGTCCGCAGCGCGGATCGC

Downstream 100 bases:

>100_bases
GGCTGACCCGGCACCCGGACCTGCTCGACCGCATGGCAGCGCAATATGCGCTCGGCGTGCTCCGTGGCGGCGCACGGCGC
CGGATGGAGCAGCTTGCGCG

Product: sigma-70 region 2:sigma-70 region 4

Products: NA

Alternate protein names: Sigma-K factor [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MLLLRRHRAIGCSDAAYNPSEPSARNLHVPAAPEPSFAPSADNDRLAAWLQAVALGDRQALRALYDHTATKLFGLALRIT
GRRDWAEDAVQESFVSIWHHAGDYRPHLAAPMTWMTTIVRNRALDCLRRAAAARVPQTVELDEELGEWLADDAAGPAELA
LASQQARALNRCLQRLEPAQRQAIVLAYLRDLSHAELSERLRLPLGTVKSWIRRGLERLRACLESAP

Sequences:

>Translated_227_residues
MLLLRRHRAIGCSDAAYNPSEPSARNLHVPAAPEPSFAPSADNDRLAAWLQAVALGDRQALRALYDHTATKLFGLALRIT
GRRDWAEDAVQESFVSIWHHAGDYRPHLAAPMTWMTTIVRNRALDCLRRAAAARVPQTVELDEELGEWLADDAAGPAELA
LASQQARALNRCLQRLEPAQRQAIVLAYLRDLSHAELSERLRLPLGTVKSWIRRGLERLRACLESAP
>Mature_227_residues
MLLLRRHRAIGCSDAAYNPSEPSARNLHVPAAPEPSFAPSADNDRLAAWLQAVALGDRQALRALYDHTATKLFGLALRIT
GRRDWAEDAVQESFVSIWHHAGDYRPHLAAPMTWMTTIVRNRALDCLRRAAAARVPQTVELDEELGEWLADDAAGPAELA
LASQQARALNRCLQRLEPAQRQAIVLAYLRDLSHAELSERLRLPLGTVKSWIRRGLERLRACLESAP

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR007627
- InterPro:   IPR007630
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF04545 Sigma70_r4 [H]

EC number: NA

Molecular weight: Translated: 25275; Mature: 25275

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLLRRHRAIGCSDAAYNPSEPSARNLHVPAAPEPSFAPSADNDRLAAWLQAVALGDRQA
CCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHCHHHH
LRALYDHTATKLFGLALRITGRRDWAEDAVQESFVSIWHHAGDYRPHLAAPMTWMTTIVR
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
NRALDCLRRAAAARVPQTVELDEELGEWLADDAAGPAELALASQQARALNRCLQRLEPAQ
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCHHH
RQAIVLAYLRDLSHAELSERLRLPLGTVKSWIRRGLERLRACLESAP
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLLLRRHRAIGCSDAAYNPSEPSARNLHVPAAPEPSFAPSADNDRLAAWLQAVALGDRQA
CCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHCHHHH
LRALYDHTATKLFGLALRITGRRDWAEDAVQESFVSIWHHAGDYRPHLAAPMTWMTTIVR
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
NRALDCLRRAAAARVPQTVELDEELGEWLADDAAGPAELALASQQARALNRCLQRLEPAQ
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCHHH
RQAIVLAYLRDLSHAELSERLRLPLGTVKSWIRRGLERLRACLESAP
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA