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The map label for this gene is adiA [H]

Identifier: 73540395

GI number: 73540395

Start: 741837

End: 744107

Strand: Direct

Name: adiA [H]

Synonym: Reut_A0689

Alternate gene names: 73540395

Gene position: 741837-744107 (Clockwise)

Preceding gene: 73540394

Following gene: 73540397

Centisome position: 19.49

GC content: 63.36

Gene sequence:

>2271_bases
ATGAAATTCCGCTTCCCCGTCATCATCATTGACGAAGACTTCCGCTCCGAGAACATCTCCGGCTCGGGTATCCGCGCGCT
GGCCGAGGCGATCGAGAAAGAGGGGATGGAGGTCATGGGCCTGACCAGCTACGGCGACCTGACCTCGTTCGCGCAGCAGT
CCAGCCGCGCTTCGACCTTTATCGTGTCGATCGACGACGACGAGTTCGTGACCGCCGATGACCAGCCCGAAGCGGCCGCC
ATCGAAAAGCTGCGCGCATTCGTCAATGAAGTGCGCCGCCGCAACACCGACCTGCCGATCTTCCTGTACGGCGAGACCCG
CACCTCGCGCCATATCCCGAACGATATCCTGCGCGAGCTGCACGGCTTCATCCACATGTTCGAGGACACGCCCGAGTTCG
TGGCGCGCCACATCATCCGCGAAGCCAAGGTCTACCTCGACACGCTCGCGCCGCCGTTCTTCAAGGCGCTGATCGACTAC
GCGCAGGATTCGTCGTACTCGTGGCACTGCCCGGGACACTCGGGCGGCGTGGCGTTCCTGAAGAGCCCGGTGGGCCAGGT
GTTCCACCAGTTCTTCGGCGAAAACATGCTGCGTGCCGATGTCTGCAACGCGGTGGATGAACTCGGCCAGCTGCTGGACC
ACACCGGCCCGGTGGCCGCGTCCGAGCGCAACGCCGCGCGTATCTTCAACTCGGACCACATGTTCTTCGTGACCAACGGC
ACGTCGACGTCGAACAAGATGGTGTGGCACGCCAACGTGGCGCCCGGCGACATCGTCGTGGTGGACCGCAACTGCCACAA
GTCGATCCTGCACGCGATCATGATGACCGGCGCGATCCCCGTGTTCCTGATGCCGACGCGCAACCACTACGGCATCATCG
GCCCGATCCCCAAGAGCGAGTTCGACCCGGAGACCATCCGCAGGAAGATCGCCAACCACCCGTTCGCAAGCAAGGCCAAG
AACCAGAAGCCGCGCATCCTGACGATCACGCAGGGTACCTACGACGGCGTGCTGTACAACGCCGAGCAGATCAAGGAGAT
GCTCGCGTCGGAAATCGACACGCTGCATTTCGATGAAGCGTGGCTGCCGCACGCGGCGTTCCACGAGTTCTATCACAACA
TGCACGCGATCGGCCGTGACCGCCCGCGCAGCAAGGACGCGCTGGTGTTTGCCACGCAGTCCACGCACAAGCTGCTGGCG
GGCCTGTCGCAGGCGTCGCAGATCCTCGTGCAGGATTCCGAAACGCGCAAGCTGGACCGCTATCGCTTCAACGAGGCGTA
CCTGATGCACACCTCGACCAGTCCGCAGTACGCGATCATCGCCTCGTGCGATGTCGCCGCGGCCATGATGGAAGCGCCGG
GCGGCCCCGCGCTGGTGGAAGAAAGCATCCAGGAAGCACTGGACTTCCGCCGCGCCATGCGCAAGGTCGAAGGCGACTTC
GAAGCCGGCAACAATGGCGACTGGTGGTTCAAGGTCTGGGGCCCGGATACGCTGAACGACGAAGGCATGCCCGAACGCGA
GCAGTGGATGCTCAAGGCCAACGAGCGCTGGCACGGCTTCGGCGACCTGGCCGACGGCTTCAACCTGCTCGACCCGATCA
AGGCGACGATCATCACCCCGGGCCTGGACGTGGACGGCGAGTTCAGCGATCGCGGCATTCCGGCGGCCATCGTCACCAAG
TACCTGGCCGAGCACGGCATCATCATCGAGAAGACGGGCCTGTACTCGTTCTTCATCATGTTCACCATCGGCATTACCAA
GGGCCGCTGGAATTCGCTGGTGACCGAGTTGCAGCAGTTCAAGGACGACTACGACCAGAACCAGCCGCTGTGGCGCGTGC
TGCCCGAGTTCGTTGGCAAGCATCCACAGTACGAACGCATGGGCCTGCGTGACCTGTGCGATGCCGTGCACAGCGTCTAC
AAGGCCAACGACGTGGCGCGCGTGACGACAGAGATGTACCTGTCGGACATGGAACCGGCGATGAAGCCGTCAGACGCGTG
GTCGATGATGGCGCACCGCGAGATCGAGCGCGTGCCGGTGGACGACCTGGAGGGCCGAGTCACCGCCATCCTGCTGACGC
CGTACCCGCCGGGCATCCCGCTGCTGATCCCGGGCGAGCGCTTCAACCGCACCATCGTCCAGTACCTGAAGTTCGCGCGC
GAGTTCAACAAGCTGTTCCCGGGCTTCGAGACCGATGTGCACGGGCTGGTCGAGGAAGAGGTCGATGGCCGCAAGGCGTA
CTTCGTGGATTGCGTAAAGCAGGGCAGCTAA

Upstream 100 bases:

>100_bases
CCAAGACCTGACGTGAGAGCCACATGTCGCCGCAGCAGGGGAACCCCTGCCGGCCATGTGGCTCAGTCCTTTATGTCCTG
CTTTCCATCAAGGATGCCCG

Downstream 100 bases:

>100_bases
ATTCACGACCACGCGACCACTGCCGACGTAGCGATGCGCCGGCCTGCCAGATGGCAGGCCGGCGTTTTTTACGCATGCGG
CCGCTGCTTCGTCATCACGC

Product: ornithine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 756; Mature: 756

Protein sequence:

>756_residues
MKFRFPVIIIDEDFRSENISGSGIRALAEAIEKEGMEVMGLTSYGDLTSFAQQSSRASTFIVSIDDDEFVTADDQPEAAA
IEKLRAFVNEVRRRNTDLPIFLYGETRTSRHIPNDILRELHGFIHMFEDTPEFVARHIIREAKVYLDTLAPPFFKALIDY
AQDSSYSWHCPGHSGGVAFLKSPVGQVFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFNSDHMFFVTNG
TSTSNKMVWHANVAPGDIVVVDRNCHKSILHAIMMTGAIPVFLMPTRNHYGIIGPIPKSEFDPETIRRKIANHPFASKAK
NQKPRILTITQGTYDGVLYNAEQIKEMLASEIDTLHFDEAWLPHAAFHEFYHNMHAIGRDRPRSKDALVFATQSTHKLLA
GLSQASQILVQDSETRKLDRYRFNEAYLMHTSTSPQYAIIASCDVAAAMMEAPGGPALVEESIQEALDFRRAMRKVEGDF
EAGNNGDWWFKVWGPDTLNDEGMPEREQWMLKANERWHGFGDLADGFNLLDPIKATIITPGLDVDGEFSDRGIPAAIVTK
YLAEHGIIIEKTGLYSFFIMFTIGITKGRWNSLVTELQQFKDDYDQNQPLWRVLPEFVGKHPQYERMGLRDLCDAVHSVY
KANDVARVTTEMYLSDMEPAMKPSDAWSMMAHREIERVPVDDLEGRVTAILLTPYPPGIPLLIPGERFNRTIVQYLKFAR
EFNKLFPGFETDVHGLVEEEVDGRKAYFVDCVKQGS

Sequences:

>Translated_756_residues
MKFRFPVIIIDEDFRSENISGSGIRALAEAIEKEGMEVMGLTSYGDLTSFAQQSSRASTFIVSIDDDEFVTADDQPEAAA
IEKLRAFVNEVRRRNTDLPIFLYGETRTSRHIPNDILRELHGFIHMFEDTPEFVARHIIREAKVYLDTLAPPFFKALIDY
AQDSSYSWHCPGHSGGVAFLKSPVGQVFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFNSDHMFFVTNG
TSTSNKMVWHANVAPGDIVVVDRNCHKSILHAIMMTGAIPVFLMPTRNHYGIIGPIPKSEFDPETIRRKIANHPFASKAK
NQKPRILTITQGTYDGVLYNAEQIKEMLASEIDTLHFDEAWLPHAAFHEFYHNMHAIGRDRPRSKDALVFATQSTHKLLA
GLSQASQILVQDSETRKLDRYRFNEAYLMHTSTSPQYAIIASCDVAAAMMEAPGGPALVEESIQEALDFRRAMRKVEGDF
EAGNNGDWWFKVWGPDTLNDEGMPEREQWMLKANERWHGFGDLADGFNLLDPIKATIITPGLDVDGEFSDRGIPAAIVTK
YLAEHGIIIEKTGLYSFFIMFTIGITKGRWNSLVTELQQFKDDYDQNQPLWRVLPEFVGKHPQYERMGLRDLCDAVHSVY
KANDVARVTTEMYLSDMEPAMKPSDAWSMMAHREIERVPVDDLEGRVTAILLTPYPPGIPLLIPGERFNRTIVQYLKFAR
EFNKLFPGFETDVHGLVEEEVDGRKAYFVDCVKQGS
>Mature_756_residues
MKFRFPVIIIDEDFRSENISGSGIRALAEAIEKEGMEVMGLTSYGDLTSFAQQSSRASTFIVSIDDDEFVTADDQPEAAA
IEKLRAFVNEVRRRNTDLPIFLYGETRTSRHIPNDILRELHGFIHMFEDTPEFVARHIIREAKVYLDTLAPPFFKALIDY
AQDSSYSWHCPGHSGGVAFLKSPVGQVFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFNSDHMFFVTNG
TSTSNKMVWHANVAPGDIVVVDRNCHKSILHAIMMTGAIPVFLMPTRNHYGIIGPIPKSEFDPETIRRKIANHPFASKAK
NQKPRILTITQGTYDGVLYNAEQIKEMLASEIDTLHFDEAWLPHAAFHEFYHNMHAIGRDRPRSKDALVFATQSTHKLLA
GLSQASQILVQDSETRKLDRYRFNEAYLMHTSTSPQYAIIASCDVAAAMMEAPGGPALVEESIQEALDFRRAMRKVEGDF
EAGNNGDWWFKVWGPDTLNDEGMPEREQWMLKANERWHGFGDLADGFNLLDPIKATIITPGLDVDGEFSDRGIPAAIVTK
YLAEHGIIIEKTGLYSFFIMFTIGITKGRWNSLVTELQQFKDDYDQNQPLWRVLPEFVGKHPQYERMGLRDLCDAVHSVY
KANDVARVTTEMYLSDMEPAMKPSDAWSMMAHREIERVPVDDLEGRVTAILLTPYPPGIPLLIPGERFNRTIVQYLKFAR
EFNKLFPGFETDVHGLVEEEVDGRKAYFVDCVKQGS

Specific function: ADC can be found in two forms:biodegradative and biosynthetic. The biodegradative form may play a role in regulating pH by consuming proteins [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI221142684, Length=768, Percent_Identity=38.4114583333333, Blast_Score=550, Evalue=1e-157,
Organism=Escherichia coli, GI1790573, Length=737, Percent_Identity=36.6350067842605, Blast_Score=502, Evalue=1e-143,
Organism=Escherichia coli, GI1786384, Length=721, Percent_Identity=37.0319001386963, Blast_Score=496, Evalue=1e-141,
Organism=Escherichia coli, GI1786909, Length=685, Percent_Identity=32.992700729927, Blast_Score=380, Evalue=1e-106,
Organism=Escherichia coli, GI87082193, Length=724, Percent_Identity=33.1491712707182, Blast_Score=368, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005308
- InterPro:   IPR011193
- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 85472; Mature: 85472

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00142 ZINC_PROTEASE ; PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFRFPVIIIDEDFRSENISGSGIRALAEAIEKEGMEVMGLTSYGDLTSFAQQSSRASTF
CCEECCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCEEE
IVSIDDDEFVTADDQPEAAAIEKLRAFVNEVRRRNTDLPIFLYGETRTSRHIPNDILREL
EEEECCCCEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHH
HGFIHMFEDTPEFVARHIIREAKVYLDTLAPPFFKALIDYAQDSSYSWHCPGHSGGVAFL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEECCCCCCCHHHH
KSPVGQVFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFNSDHMFFVTNG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEECCCCEEEEECC
TSTSNKMVWHANVAPGDIVVVDRNCHKSILHAIMMTGAIPVFLMPTRNHYGIIGPIPKSE
CCCCCEEEEEECCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCEEECCCCCCC
FDPETIRRKIANHPFASKAKNQKPRILTITQGTYDGVLYNAEQIKEMLASEIDTLHFDEA
CCHHHHHHHHHCCCCHHHCCCCCCCEEEEECCCCCCEEECHHHHHHHHHHHHCCEECCCC
WLPHAAFHEFYHNMHAIGRDRPRSKDALVFATQSTHKLLAGLSQASQILVQDSETRKLDR
CCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECHHHHHHHHHHHHHHEEECCCCHHHHHH
YRFNEAYLMHTSTSPQYAIIASCDVAAAMMEAPGGPALVEESIQEALDFRRAMRKVEGDF
EECCCEEEEEECCCCCEEEEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
EAGNNGDWWFKVWGPDTLNDEGMPEREQWMLKANERWHGFGDLADGFNLLDPIKATIITP
CCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHCCCCHHCCHHHHEECC
GLDVDGEFSDRGIPAAIVTKYLAEHGIIIEKTGLYSFFIMFTIGITKGRWNSLVTELQQF
CCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHH
KDDYDQNQPLWRVLPEFVGKHPQYERMGLRDLCDAVHSVYKANDVARVTTEMYLSDMEPA
HHHHCCCCCHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
MKPSDAWSMMAHREIERVPVDDLEGRVTAILLTPYPPGIPLLIPGERFNRTIVQYLKFAR
CCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCEEECCHHHHHHHHHHHHHHH
EFNKLFPGFETDVHGLVEEEVDGRKAYFVDCVKQGS
HHHHHCCCCCCHHHHHHHHHCCCCCEEEEHHHCCCC
>Mature Secondary Structure
MKFRFPVIIIDEDFRSENISGSGIRALAEAIEKEGMEVMGLTSYGDLTSFAQQSSRASTF
CCEECCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCEEE
IVSIDDDEFVTADDQPEAAAIEKLRAFVNEVRRRNTDLPIFLYGETRTSRHIPNDILREL
EEEECCCCEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHH
HGFIHMFEDTPEFVARHIIREAKVYLDTLAPPFFKALIDYAQDSSYSWHCPGHSGGVAFL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEECCCCCCCHHHH
KSPVGQVFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFNSDHMFFVTNG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEECCCCEEEEECC
TSTSNKMVWHANVAPGDIVVVDRNCHKSILHAIMMTGAIPVFLMPTRNHYGIIGPIPKSE
CCCCCEEEEEECCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCEEECCCCCCC
FDPETIRRKIANHPFASKAKNQKPRILTITQGTYDGVLYNAEQIKEMLASEIDTLHFDEA
CCHHHHHHHHHCCCCHHHCCCCCCCEEEEECCCCCCEEECHHHHHHHHHHHHCCEECCCC
WLPHAAFHEFYHNMHAIGRDRPRSKDALVFATQSTHKLLAGLSQASQILVQDSETRKLDR
CCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECHHHHHHHHHHHHHHEEECCCCHHHHHH
YRFNEAYLMHTSTSPQYAIIASCDVAAAMMEAPGGPALVEESIQEALDFRRAMRKVEGDF
EECCCEEEEEECCCCCEEEEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
EAGNNGDWWFKVWGPDTLNDEGMPEREQWMLKANERWHGFGDLADGFNLLDPIKATIITP
CCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHCCCCHHCCHHHHEECC
GLDVDGEFSDRGIPAAIVTKYLAEHGIIIEKTGLYSFFIMFTIGITKGRWNSLVTELQQF
CCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHH
KDDYDQNQPLWRVLPEFVGKHPQYERMGLRDLCDAVHSVYKANDVARVTTEMYLSDMEPA
HHHHCCCCCHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
MKPSDAWSMMAHREIERVPVDDLEGRVTAILLTPYPPGIPLLIPGERFNRTIVQYLKFAR
CCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCEEECCHHHHHHHHHHHHHHH
EFNKLFPGFETDVHGLVEEEVDGRKAYFVDCVKQGS
HHHHHCCCCCCHHHHHHHHHCCCCCEEEEHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8383109; 7610040; 9278503; 2830169; 4204273 [H]