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The map label for this gene is mrp [H]

Identifier: 73540382

GI number: 73540382

Start: 728953

End: 730041

Strand: Direct

Name: mrp [H]

Synonym: Reut_A0676

Alternate gene names: 73540382

Gene position: 728953-730041 (Clockwise)

Preceding gene: 73540379

Following gene: 73540383

Centisome position: 19.15

GC content: 64.19

Gene sequence:

>1089_bases
TTGAGCCTCAGCACTGAACAGGTCACGGAAGTCCTGCGCACGGTCATCGATCCCAATACGGGCAAAGATCTGGTGTCCAC
CCGCTCGGCCCGGAATATCCGTGTCGACGGCGGCGACGTGTCGCTCGAGGTGGAACTCGGCTATCCGGGCAAGAGCCAGT
TCGAGCCGATTCGCAAGCTGGTTGTCGCTGCAGTGCGTCAACTGCCTGGCGTCAGCAATGTCAGCGTCAACATCAGCATG
AAGATCGTCGCCCACGCCGTGCAGCGTGGCGTCAAGCTGCTGGCTGGCGTGAAGAACGTGATTGCCGTGGCGTCGGGCAA
GGGCGGGGTGGGCAAGTCCACCACGGCGGTCAACCTGGCGCTGGCGCTGGCTGCCGAAGGCGCGCGTGTTGGCATGCTGG
ACGCCGACATCTACGGCCCGAGCCTGCCGATGATGCTGGGCATCGACGGCCGCCCGGAATCGTCCGACGGCCAGACCATG
GAGCCGCTGGAAGGCCATGGCCTGCAGGCCAATTCGATCGGTTTCCTGATCGAACAGGACAACCCCATGGTGTGGCGCGG
CCCGATGGTCACGTCGGCGCTTGAACAACTGCTGCGCCAGACCAACTGGCATGACCTCGATTACCTGATCGTCGACATGC
CACCGGGCACCGGCGACATCCAACTCACGCTGTCGCAGAAGGTGCCGGTCACGGGTGCCGTGATCGTGACCACGCCGCAG
GACATTGCACTGCTAGACGCCAAGAAGGGCCTGAAAATGTTCGAGAAGGTGGGCATCCCCATCCTGGGCATCGTCGAGAA
CATGGCGGTGTACTGCTGCCCGAACTGCGGCCACGTCGAACATATCTTCGGCCAGGGCGGCGGCGAAAAGATGTGCGCCG
ACTACGGGGTCGACCTGCTGGGCAGCCTGCCGCTGAACCTGTCGATCCGCGAACAGGCGGACTCGGGCCGCCCGACGGTG
GTATCCGACCCCGACAGCCCGGTGGCGGAGCTGTACCGTGGCATCGCCCGCAAGGTCGCCATCAAGGTGGCCGACAAGGC
TCGCGACATGACCAGCAAGTTCCCCAGCATCGTCGTGCAGAACACCTGA

Upstream 100 bases:

>100_bases
ATACAAGGGATTGCGGGCCGACTCGCGGACTTGATGGCCACTGCTTCATACTTTGATACATTAGCCTGTCCCCACTATCT
ACAAACAAGCGGAGTTTGTC

Downstream 100 bases:

>100_bases
GGCCCTGCGCCATGGAAACGAGCGCCCCGCAAGCCCGTCCCGCCGTCACCATGGCGGTGGTCATGCGCAGGGTGGCGCTG
GCCAGCCGCTGGCAGCCCTG

Product: cobyrinic acid a,c-diamide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MSLSTEQVTEVLRTVIDPNTGKDLVSTRSARNIRVDGGDVSLEVELGYPGKSQFEPIRKLVVAAVRQLPGVSNVSVNISM
KIVAHAVQRGVKLLAGVKNVIAVASGKGGVGKSTTAVNLALALAAEGARVGMLDADIYGPSLPMMLGIDGRPESSDGQTM
EPLEGHGLQANSIGFLIEQDNPMVWRGPMVTSALEQLLRQTNWHDLDYLIVDMPPGTGDIQLTLSQKVPVTGAVIVTTPQ
DIALLDAKKGLKMFEKVGIPILGIVENMAVYCCPNCGHVEHIFGQGGGEKMCADYGVDLLGSLPLNLSIREQADSGRPTV
VSDPDSPVAELYRGIARKVAIKVADKARDMTSKFPSIVVQNT

Sequences:

>Translated_362_residues
MSLSTEQVTEVLRTVIDPNTGKDLVSTRSARNIRVDGGDVSLEVELGYPGKSQFEPIRKLVVAAVRQLPGVSNVSVNISM
KIVAHAVQRGVKLLAGVKNVIAVASGKGGVGKSTTAVNLALALAAEGARVGMLDADIYGPSLPMMLGIDGRPESSDGQTM
EPLEGHGLQANSIGFLIEQDNPMVWRGPMVTSALEQLLRQTNWHDLDYLIVDMPPGTGDIQLTLSQKVPVTGAVIVTTPQ
DIALLDAKKGLKMFEKVGIPILGIVENMAVYCCPNCGHVEHIFGQGGGEKMCADYGVDLLGSLPLNLSIREQADSGRPTV
VSDPDSPVAELYRGIARKVAIKVADKARDMTSKFPSIVVQNT
>Mature_361_residues
SLSTEQVTEVLRTVIDPNTGKDLVSTRSARNIRVDGGDVSLEVELGYPGKSQFEPIRKLVVAAVRQLPGVSNVSVNISMK
IVAHAVQRGVKLLAGVKNVIAVASGKGGVGKSTTAVNLALALAAEGARVGMLDADIYGPSLPMMLGIDGRPESSDGQTME
PLEGHGLQANSIGFLIEQDNPMVWRGPMVTSALEQLLRQTNWHDLDYLIVDMPPGTGDIQLTLSQKVPVTGAVIVTTPQD
IALLDAKKGLKMFEKVGIPILGIVENMAVYCCPNCGHVEHIFGQGGGEKMCADYGVDLLGSLPLNLSIREQADSGRPTVV
SDPDSPVAELYRGIARKVAIKVADKARDMTSKFPSIVVQNT

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI157384956, Length=250, Percent_Identity=57.2, Blast_Score=288, Evalue=5e-78,
Organism=Homo sapiens, GI118572611, Length=262, Percent_Identity=40.0763358778626, Blast_Score=192, Evalue=3e-49,
Organism=Homo sapiens, GI6912540, Length=253, Percent_Identity=40.3162055335968, Blast_Score=188, Evalue=5e-48,
Organism=Escherichia coli, GI87082045, Length=337, Percent_Identity=51.9287833827893, Blast_Score=343, Evalue=1e-95,
Organism=Caenorhabditis elegans, GI25143050, Length=261, Percent_Identity=40.9961685823755, Blast_Score=193, Evalue=9e-50,
Organism=Saccharomyces cerevisiae, GI6322188, Length=259, Percent_Identity=36.6795366795367, Blast_Score=184, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6321347, Length=261, Percent_Identity=40.2298850574713, Blast_Score=181, Evalue=1e-46,
Organism=Drosophila melanogaster, GI221511043, Length=247, Percent_Identity=42.1052631578947, Blast_Score=214, Evalue=7e-56,
Organism=Drosophila melanogaster, GI24667611, Length=254, Percent_Identity=42.9133858267717, Blast_Score=195, Evalue=5e-50,
Organism=Drosophila melanogaster, GI19921440, Length=264, Percent_Identity=37.5, Blast_Score=150, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR000808 [H]

Pfam domain/function: PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 38413; Mature: 38282

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSTEQVTEVLRTVIDPNTGKDLVSTRSARNIRVDGGDVSLEVELGYPGKSQFEPIRKL
CCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEECCCCEEEEEEECCCCCHHHHHHHHH
VVAAVRQLPGVSNVSVNISMKIVAHAVQRGVKLLAGVKNVIAVASGKGGVGKSTTAVNLA
HHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHEEE
LALAAEGARVGMLDADIYGPSLPMMLGIDGRPESSDGQTMEPLEGHGLQANSIGFLIEQD
EEEECCCCEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECC
NPMVWRGPMVTSALEQLLRQTNWHDLDYLIVDMPPGTGDIQLTLSQKVPVTGAVIVTTPQ
CCEEEECCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEECCCCCCEEEEEECCC
DIALLDAKKGLKMFEKVGIPILGIVENMAVYCCPNCGHVEHIFGQGGGEKMCADYGVDLL
CEEEEEHHHHHHHHHHCCCCCEEHHHCCEEEECCCCCCHHHHHCCCCCCCHHHHCCCHHH
GSLPLNLSIREQADSGRPTVVSDPDSPVAELYRGIARKVAIKVADKARDMTSKFPSIVVQ
CCCCCCEEEECCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
NT
CC
>Mature Secondary Structure 
SLSTEQVTEVLRTVIDPNTGKDLVSTRSARNIRVDGGDVSLEVELGYPGKSQFEPIRKL
CCCHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEECCCCEEEEEEECCCCCHHHHHHHHH
VVAAVRQLPGVSNVSVNISMKIVAHAVQRGVKLLAGVKNVIAVASGKGGVGKSTTAVNLA
HHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHEEE
LALAAEGARVGMLDADIYGPSLPMMLGIDGRPESSDGQTMEPLEGHGLQANSIGFLIEQD
EEEECCCCEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECC
NPMVWRGPMVTSALEQLLRQTNWHDLDYLIVDMPPGTGDIQLTLSQKVPVTGAVIVTTPQ
CCEEEECCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEECCCCCCEEEEEECCC
DIALLDAKKGLKMFEKVGIPILGIVENMAVYCCPNCGHVEHIFGQGGGEKMCADYGVDLL
CEEEEEHHHHHHHHHHCCCCCEEHHHCCEEEECCCCCCHHHHHCCCCCCCHHHHCCCHHH
GSLPLNLSIREQADSGRPTVVSDPDSPVAELYRGIARKVAIKVADKARDMTSKFPSIVVQ
CCCCCCEEEECCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
NT
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]