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The map label for this gene is tolQ [C]

Identifier: 73540301

GI number: 73540301

Start: 645316

End: 646011

Strand: Reverse

Name: tolQ [C]

Synonym: Reut_A0595

Alternate gene names: 73540301

Gene position: 646011-645316 (Counterclockwise)

Preceding gene: 73540305

Following gene: 73540300

Centisome position: 16.97

GC content: 66.24

Gene sequence:

>696_bases
ATGCGCGTATCCAAGGGCTGCCATATAAAGCCGGTCCGTTTTCTGTCGTCTCTGGTTGTCGATTCGGGGGTCCAATTGTT
TTCGATCATTCAAGCGGCCGGCTGGCCGATCTGGCCGCTGCTGCTCGCTTCGGTTCTCGCGCTGGCACTGATCGTCGAGC
GCTTCCTCACCCTCAAGCGCAGCAAGGTGCTTCCCGCGCGCCTCTACGAAGAGGCGCTGTCGGCGGCGCAGCAGCGCCGC
GCCACGCCCGAGGTGGTCAATACGCTGGAACAGAACTCCCCGCTGGGCCGCGTGCTCGCGGCCGGGCTCCGTCACGTAGT
GCTGCAGCCCCATACGTCGCGCGATGCCGCCAAGGAAGTCGTGGAGGAAGCGGGCCGTGCGGTTGCCCATGAGCTCGAGC
GCTACCTGAACGCGCTGGGCACCATTGCGTCGGTGGCGCCGCTGATGGGCCTGCTCGGCACGGTGATCGGCATGATCGAG
ATCTTCGGCAGCCAGGGCGGCACCGGCGCGAATCCCGAGCAGCTTGCGCACGGGATCTCGGTGGCCTTGTACAACACCGC
GTTCGGCCTGATCGTCGCAATTCCGGCGCTGATCTTCTGGCGCTATTTCCGCCGCCGCGTCGACGACTACGTGGCCGAGC
TGGAATTCCGCGCGACGGCGTTCCTCGACGCCATCCTGCCGCAACGGCGCGCCTGA

Upstream 100 bases:

>100_bases
CCGCCGAGACACCGTTTGCCAGTGTCTTGCCGCGCGCCATGGCGCGGGTTAGAGTGCTGCCTGATTTTTCGAGCAGTGCC
GCTGCGCGCAGTGCCTCGGT

Downstream 100 bases:

>100_bases
GCGCCGGCATCCACGCAGGAAGCGCCATGCAATTCCGTTCCCGACAGCGGCGTGAAGAGCCGGAAATCAACCTGATTCCG
CTCATCGATGTGCTGCTCGT

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MRVSKGCHIKPVRFLSSLVVDSGVQLFSIIQAAGWPIWPLLLASVLALALIVERFLTLKRSKVLPARLYEEALSAAQQRR
ATPEVVNTLEQNSPLGRVLAAGLRHVVLQPHTSRDAAKEVVEEAGRAVAHELERYLNALGTIASVAPLMGLLGTVIGMIE
IFGSQGGTGANPEQLAHGISVALYNTAFGLIVAIPALIFWRYFRRRVDDYVAELEFRATAFLDAILPQRRA

Sequences:

>Translated_231_residues
MRVSKGCHIKPVRFLSSLVVDSGVQLFSIIQAAGWPIWPLLLASVLALALIVERFLTLKRSKVLPARLYEEALSAAQQRR
ATPEVVNTLEQNSPLGRVLAAGLRHVVLQPHTSRDAAKEVVEEAGRAVAHELERYLNALGTIASVAPLMGLLGTVIGMIE
IFGSQGGTGANPEQLAHGISVALYNTAFGLIVAIPALIFWRYFRRRVDDYVAELEFRATAFLDAILPQRRA
>Mature_231_residues
MRVSKGCHIKPVRFLSSLVVDSGVQLFSIIQAAGWPIWPLLLASVLALALIVERFLTLKRSKVLPARLYEEALSAAQQRR
ATPEVVNTLEQNSPLGRVLAAGLRHVVLQPHTSRDAAKEVVEEAGRAVAHELERYLNALGTIASVAPLMGLLGTVIGMIE
IFGSQGGTGANPEQLAHGISVALYNTAFGLIVAIPALIFWRYFRRRVDDYVAELEFRATAFLDAILPQRRA

Specific function: Involved In The Tonb-Independent Uptake Of Group A Colicins (Colicins A, E1, E2, E3, And K). [C]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=188, Percent_Identity=27.1276595744681, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 25228; Mature: 25228

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: PS00141 ASP_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVSKGCHIKPVRFLSSLVVDSGVQLFSIIQAAGWPIWPLLLASVLALALIVERFLTLKR
CCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SKVLPARLYEEALSAAQQRRATPEVVNTLEQNSPLGRVLAAGLRHVVLQPHTSRDAAKEV
HCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHH
VEEAGRAVAHELERYLNALGTIASVAPLMGLLGTVIGMIEIFGSQGGTGANPEQLAHGIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
VALYNTAFGLIVAIPALIFWRYFRRRVDDYVAELEFRATAFLDAILPQRRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRVSKGCHIKPVRFLSSLVVDSGVQLFSIIQAAGWPIWPLLLASVLALALIVERFLTLKR
CCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SKVLPARLYEEALSAAQQRRATPEVVNTLEQNSPLGRVLAAGLRHVVLQPHTSRDAAKEV
HCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHH
VEEAGRAVAHELERYLNALGTIASVAPLMGLLGTVIGMIEIFGSQGGTGANPEQLAHGIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
VALYNTAFGLIVAIPALIFWRYFRRRVDDYVAELEFRATAFLDAILPQRRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]