Click here to switch to the map view.

The map label for this gene is corC [H]

Identifier: 73540217

GI number: 73540217

Start: 555892

End: 556773

Strand: Reverse

Name: corC [H]

Synonym: Reut_A0511

Alternate gene names: 73540217

Gene position: 556773-555892 (Counterclockwise)

Preceding gene: 73540218

Following gene: 73540216

Centisome position: 14.63

GC content: 62.36

Gene sequence:

>882_bases
ATGAACGACCCCTATCCCAGTTCGAAGCCTGCCCATTTCAAGCAGTCCGATCGCCCCAGATCGCTTCTCGAACGCCTCAC
CGACCTGATTTCCCCTGAGCCCGAATCCCGCGCGGAGCTGCTTGCCGTGCTGCAGGATGCGCACGAGCGCAACCTGATCG
ACGCCGATTCGCTTTCCATGATCGAAGGCGTATTCCAGGTCTCCGAACTGACCGCGCGCGACATCATGGTGCAGCGCTCG
CAGATGGATATGGTCAACATCGCGGACGCGCCGCAGGCCTTCATTCCCTTCATGCAGCTGACGGCGCACTCGCGCTTTCC
GGTGTACGAAGGCAGCCGCGACAACATCATCGGCATCCTGCTGGCCAAGGACCTGCTGCGCTACTACACGGACGAGCAGT
TCGACCTGCGCGAAACGCTGCGTCCGGCCGTGTTCATCCCGGAATCGAAGCGCCTGAACATCCTGCTGCGCGAGTTCCGC
AACAACCGCAACCACATTGCCATCGTCGTCGATGAATACGGCGGCGTGGCCGGACTGGTCACGATCGAAGATGTGCTCGA
GCAGATCGTCGGCGACATCGAGGACGAATTCGATCTCGACGAAGACCAGGACAACATTCTGCCACTGCCCGACGGCGGCT
GGCGCGTGCATGGCCTCACCGAGATCTCGCAGTTCAATGAGGCCTTCGGCACGGCGTTCTCGGACCACGACGTCGATACC
GTGGGCGGGCTGCTGACCAACCATCTCGGCCACGTGCCGCATCGCGGCGAGATTATTACGCTGCCGCCGGTCAGCTTCGA
AGTGCTGCGCGCCGATGCGCGCCAGGTGCACCTGCTTCTCGTGCACCGCGAGTCGTCCACGAACCACCTGACCGACGCAT
GA

Upstream 100 bases:

>100_bases
TCCGCCCGCACACAGTCGGCCGCCCCGCCGGCTGTGTCACGAGAGTAAACGGTCTTTTAGTGTATCCTTCAGACGATCTC
CACCACGCGCTTGCCGCGAA

Downstream 100 bases:

>100_bases
AGCGCCAGGCTCCTGCCCTGGCCGCCGCCACCGGCGCCGAACGCACACGCGTGTCCGGCGCGACCATGGCGCGCCTGCTG
CTCGCGGGCATGCTCGGCAT

Product: CBS:transporter-associated region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MNDPYPSSKPAHFKQSDRPRSLLERLTDLISPEPESRAELLAVLQDAHERNLIDADSLSMIEGVFQVSELTARDIMVQRS
QMDMVNIADAPQAFIPFMQLTAHSRFPVYEGSRDNIIGILLAKDLLRYYTDEQFDLRETLRPAVFIPESKRLNILLREFR
NNRNHIAIVVDEYGGVAGLVTIEDVLEQIVGDIEDEFDLDEDQDNILPLPDGGWRVHGLTEISQFNEAFGTAFSDHDVDT
VGGLLTNHLGHVPHRGEIITLPPVSFEVLRADARQVHLLLVHRESSTNHLTDA

Sequences:

>Translated_293_residues
MNDPYPSSKPAHFKQSDRPRSLLERLTDLISPEPESRAELLAVLQDAHERNLIDADSLSMIEGVFQVSELTARDIMVQRS
QMDMVNIADAPQAFIPFMQLTAHSRFPVYEGSRDNIIGILLAKDLLRYYTDEQFDLRETLRPAVFIPESKRLNILLREFR
NNRNHIAIVVDEYGGVAGLVTIEDVLEQIVGDIEDEFDLDEDQDNILPLPDGGWRVHGLTEISQFNEAFGTAFSDHDVDT
VGGLLTNHLGHVPHRGEIITLPPVSFEVLRADARQVHLLLVHRESSTNHLTDA
>Mature_293_residues
MNDPYPSSKPAHFKQSDRPRSLLERLTDLISPEPESRAELLAVLQDAHERNLIDADSLSMIEGVFQVSELTARDIMVQRS
QMDMVNIADAPQAFIPFMQLTAHSRFPVYEGSRDNIIGILLAKDLLRYYTDEQFDLRETLRPAVFIPESKRLNILLREFR
NNRNHIAIVVDEYGGVAGLVTIEDVLEQIVGDIEDEFDLDEDQDNILPLPDGGWRVHGLTEISQFNEAFGTAFSDHDVDT
VGGLLTNHLGHVPHRGEIITLPPVSFEVLRADARQVHLLLVHRESSTNHLTDA

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=216, Percent_Identity=31.4814814814815, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI94681046, Length=182, Percent_Identity=31.3186813186813, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI40068053, Length=185, Percent_Identity=29.1891891891892, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI40068055, Length=185, Percent_Identity=29.1891891891892, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1786879, Length=258, Percent_Identity=45.7364341085271, Blast_Score=207, Evalue=5e-55,
Organism=Escherichia coli, GI145693175, Length=234, Percent_Identity=28.6324786324786, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI87082033, Length=269, Percent_Identity=26.3940520446097, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788119, Length=230, Percent_Identity=32.6086956521739, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1790664, Length=229, Percent_Identity=25.764192139738, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 33091; Mature: 33091

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDPYPSSKPAHFKQSDRPRSLLERLTDLISPEPESRAELLAVLQDAHERNLIDADSLSM
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHH
IEGVFQVSELTARDIMVQRSQMDMVNIADAPQAFIPFMQLTAHSRFPVYEGSRDNIIGIL
HHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEHHH
LAKDLLRYYTDEQFDLRETLRPAVFIPESKRLNILLREFRNNRNHIAIVVDEYGGVAGLV
HHHHHHHHHCCCCCCHHHHCCCEEECCCCCHHHHHHHHHHCCCCEEEEEEECCCCEEEEH
TIEDVLEQIVGDIEDEFDLDEDQDNILPLPDGGWRVHGLTEISQFNEAFGTAFSDHDVDT
HHHHHHHHHHHCCHHHCCCCCCCCCEEECCCCCEEEECHHHHHHHHHHHCCCCCCCCHHH
VGGLLTNHLGHVPHRGEIITLPPVSFEVLRADARQVHLLLVHRESSTNHLTDA
HHHHHHHHHCCCCCCCCEEEECCCCHHHHHHCCCEEEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MNDPYPSSKPAHFKQSDRPRSLLERLTDLISPEPESRAELLAVLQDAHERNLIDADSLSM
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHH
IEGVFQVSELTARDIMVQRSQMDMVNIADAPQAFIPFMQLTAHSRFPVYEGSRDNIIGIL
HHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEHHH
LAKDLLRYYTDEQFDLRETLRPAVFIPESKRLNILLREFRNNRNHIAIVVDEYGGVAGLV
HHHHHHHHHCCCCCCHHHHCCCEEECCCCCHHHHHHHHHHCCCCEEEEEEECCCCEEEEH
TIEDVLEQIVGDIEDEFDLDEDQDNILPLPDGGWRVHGLTEISQFNEAFGTAFSDHDVDT
HHHHHHHHHHHCCHHHCCCCCCCCCEEECCCCCEEEECHHHHHHHHHHHCCCCCCCCHHH
VGGLLTNHLGHVPHRGEIITLPPVSFEVLRADARQVHLLLVHRESSTNHLTDA
HHHHHHHHHCCCCCCCCEEEECCCCHHHHHHCCCEEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]