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The map label for this gene is ruvA [H]

Identifier: 73540190

GI number: 73540190

Start: 527044

End: 527625

Strand: Reverse

Name: ruvA [H]

Synonym: Reut_A0484

Alternate gene names: 73540190

Gene position: 527625-527044 (Counterclockwise)

Preceding gene: 73540191

Following gene: 73540189

Centisome position: 13.86

GC content: 65.98

Gene sequence:

>582_bases
ATGATCGGACGCATCGCCGGCACGCTTATCGAGAAGAACCCTCCGCACCTGCTGGTGGACTGCCACGGCGTCGGCTACGA
GATCGATGTGCCGATGAGCACGTTCTACAACCTGCCCGCGACCGGCCAGCCGGTCACGCTACTCACGCAGCTGATCGTGC
GCGAGGACGCGCACCTGCTCTATGGCTTCGGCAGCGCGGCCGAGCGCAATACGTTCCGCGAGCTGATCAAGATCACCGGT
ATCGGCGCACGCATGGCGCTGGCGGTGCTGTCGGGCATGTCGGTGTCGGAGCTGGCCCAGGCCATCACGTTGCAGGAAGC
CGGACGCCTCACGCGCGTGCCGGGCATCGGCAAGAAGACCGCCGAGCGGCTGATGCTGGAACTCAAGGGCAAGCTTGGTG
CCGAACTCGGCCACGCGCCAGGCGCGGCGCCTGTGCACGACAGCGCGGTCGATATCCTTAACGCGCTGCTGGCACTCGGC
TATTCGGAAAAGGAAGCGGCCACGGCCATCAAGCAGGTTCCCGCCGGCACGGGTGTCTCGGACGGCATCAAGCTGGCGCT
GAAGGCCTTGTCCAAGGCGTGA

Upstream 100 bases:

>100_bases
CGCGCCATCGACGCAGGAACTCCGTGAATCCGCGGCACGCCGCTGGGCTACACTTGCGGCCTTCCGCAAAAACGTTGAAC
CGACCTTTACTGCAAACACC

Downstream 100 bases:

>100_bases
GGCGTAAAATAGCGCGATACCAGACGCCGCAGCCATGATTGAAACCGACAAGTTTTCCGCCCCCGACCGCGTGATCTCGG
CCACGCCCGCTTCCTCGCGC

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MIGRIAGTLIEKNPPHLLVDCHGVGYEIDVPMSTFYNLPATGQPVTLLTQLIVREDAHLLYGFGSAAERNTFRELIKITG
IGARMALAVLSGMSVSELAQAITLQEAGRLTRVPGIGKKTAERLMLELKGKLGAELGHAPGAAPVHDSAVDILNALLALG
YSEKEAATAIKQVPAGTGVSDGIKLALKALSKA

Sequences:

>Translated_193_residues
MIGRIAGTLIEKNPPHLLVDCHGVGYEIDVPMSTFYNLPATGQPVTLLTQLIVREDAHLLYGFGSAAERNTFRELIKITG
IGARMALAVLSGMSVSELAQAITLQEAGRLTRVPGIGKKTAERLMLELKGKLGAELGHAPGAAPVHDSAVDILNALLALG
YSEKEAATAIKQVPAGTGVSDGIKLALKALSKA
>Mature_193_residues
MIGRIAGTLIEKNPPHLLVDCHGVGYEIDVPMSTFYNLPATGQPVTLLTQLIVREDAHLLYGFGSAAERNTFRELIKITG
IGARMALAVLSGMSVSELAQAITLQEAGRLTRVPGIGKKTAERLMLELKGKLGAELGHAPGAAPVHDSAVDILNALLALG
YSEKEAATAIKQVPAGTGVSDGIKLALKALSKA

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=201, Percent_Identity=43.7810945273632, Blast_Score=168, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 20187; Mature: 20187

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGRIAGTLIEKNPPHLLVDCHGVGYEIDVPMSTFYNLPATGQPVTLLTQLIVREDAHLL
CCCCHHHHHHCCCCCEEEEEECCCCEEEECCHHHHHCCCCCCCHHHHHHHHHHHCCCCEE
YGFGSAAERNTFRELIKITGIGARMALAVLSGMSVSELAQAITLQEAGRLTRVPGIGKKT
EECCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHH
AERLMLELKGKLGAELGHAPGAAPVHDSAVDILNALLALGYSEKEAATAIKQVPAGTGVS
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCH
DGIKLALKALSKA
HHHHHHHHHHHCC
>Mature Secondary Structure
MIGRIAGTLIEKNPPHLLVDCHGVGYEIDVPMSTFYNLPATGQPVTLLTQLIVREDAHLL
CCCCHHHHHHCCCCCEEEEEECCCCEEEECCHHHHHCCCCCCCHHHHHHHHHHHCCCCEE
YGFGSAAERNTFRELIKITGIGARMALAVLSGMSVSELAQAITLQEAGRLTRVPGIGKKT
EECCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHH
AERLMLELKGKLGAELGHAPGAAPVHDSAVDILNALLALGYSEKEAATAIKQVPAGTGVS
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCH
DGIKLALKALSKA
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA