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The map label for this gene is gpmB [H]

Identifier: 73540185

GI number: 73540185

Start: 522908

End: 523597

Strand: Direct

Name: gpmB [H]

Synonym: Reut_A0479

Alternate gene names: 73540185

Gene position: 522908-523597 (Clockwise)

Preceding gene: 73540184

Following gene: 73540203

Centisome position: 13.74

GC content: 69.28

Gene sequence:

>690_bases
ATGCAAGGAAAGGGCATGTTGCAAAGCTCCGGGCCGCATTCGCTGGCCTACACGCACCTGATCGTGATCCGTCATGGCGA
GACGGCCTGGAACCGCGAGCGCCGGCTGCAAGGCCAGCTCGACATCCCGCTCAACGAAACCGGCGAGGCCCAGGCCCGCG
CGCTGGCGGCGGCACTGGCTGGCGAGCCGATCGACGCGGTCTATTCGAGCGACCTCGGCCGCGCCATGCAGACCGCCGCG
CCCCTGGCCGAGACACTTGGCCTCAAGGTCCGCTCCGAGCCGCGCCTGCGCGAGCGCAGCTATGGCACGCTGCAGGGCAT
GACCTACGCCGAGGTCGCCGAGAAGCTGCCCGAGGACTTCGCGCGCTGGCAGGCGCGCGTGCCCGACTACACGCCGCCGC
AGGGGGAATCGCTCGCACAATTCCATGAGCGGGCCGTCGAGATCGCGCTGTCGCTGTCGCGCCGGCATCCGGGCGAGCGT
ATCGCGCTGGTCGCACACGGCGGCGTGCTCGACTGTCTTTACCGGGAAGCCACCGGCATGACGCTGGAGGCGCCGCGCCA
GCACGAACTGCTCAACGCCAGCATCAACCGGCTACGCAGCGACAGCCATCACCTGACGCTGGCACAGTGGGGCGATGTCA
CGCACCTCGAAACGCTGGCGCTGGATGAAGTGGACCGGCGCGTCCCCTGA

Upstream 100 bases:

>100_bases
TGGCACAGGCGAGCCTGACCGGCACCTACACGCTCAATCCCAAGGTAGCTGGCTGAAGCCGGGCGGCCGGCAGGCGCCGG
TCGCTGGCAAGCGCAAGGAA

Downstream 100 bases:

>100_bases
CGCTCCGAGCGCTGCCGCGCCGCAGACCTCAGACGCGGATGCGGAACGGCGTGAAGTCGGTATTGCGGTCGTACCAGTCC
TCGTTCTCGGCGCGCTTGAG

Product: phosphoglycerate mutase

Products: NA

Alternate protein names: PGAM; Phosphoglyceromutase [H]

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MQGKGMLQSSGPHSLAYTHLIVIRHGETAWNRERRLQGQLDIPLNETGEAQARALAAALAGEPIDAVYSSDLGRAMQTAA
PLAETLGLKVRSEPRLRERSYGTLQGMTYAEVAEKLPEDFARWQARVPDYTPPQGESLAQFHERAVEIALSLSRRHPGER
IALVAHGGVLDCLYREATGMTLEAPRQHELLNASINRLRSDSHHLTLAQWGDVTHLETLALDEVDRRVP

Sequences:

>Translated_229_residues
MQGKGMLQSSGPHSLAYTHLIVIRHGETAWNRERRLQGQLDIPLNETGEAQARALAAALAGEPIDAVYSSDLGRAMQTAA
PLAETLGLKVRSEPRLRERSYGTLQGMTYAEVAEKLPEDFARWQARVPDYTPPQGESLAQFHERAVEIALSLSRRHPGER
IALVAHGGVLDCLYREATGMTLEAPRQHELLNASINRLRSDSHHLTLAQWGDVTHLETLALDEVDRRVP
>Mature_229_residues
MQGKGMLQSSGPHSLAYTHLIVIRHGETAWNRERRLQGQLDIPLNETGEAQARALAAALAGEPIDAVYSSDLGRAMQTAA
PLAETLGLKVRSEPRLRERSYGTLQGMTYAEVAEKLPEDFARWQARVPDYTPPQGESLAQFHERAVEIALSLSRRHPGER
IALVAHGGVLDCLYREATGMTLEAPRQHELLNASINRLRSDSHHLTLAQWGDVTHLETLALDEVDRRVP

Specific function: Unknown

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. GpmB subfamily [H]

Homologues:

Organism=Homo sapiens, GI9966849, Length=139, Percent_Identity=37.410071942446, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI50593010, Length=149, Percent_Identity=32.8859060402685, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4502445, Length=124, Percent_Identity=36.2903225806452, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI40353764, Length=124, Percent_Identity=36.2903225806452, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI118582286, Length=174, Percent_Identity=30.4597701149425, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1790856, Length=218, Percent_Identity=36.2385321100917, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786970, Length=201, Percent_Identity=32.3383084577114, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1786857, Length=165, Percent_Identity=30.9090909090909, Blast_Score=71, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17510917, Length=177, Percent_Identity=31.0734463276836, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI71993390, Length=177, Percent_Identity=31.0734463276836, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322697, Length=194, Percent_Identity=27.8350515463918, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324857, Length=209, Percent_Identity=30.1435406698565, Blast_Score=66, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322306, Length=159, Percent_Identity=31.4465408805031, Blast_Score=63, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24646216, Length=133, Percent_Identity=33.8345864661654, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR023086 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 25378; Mature: 25378

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGKGMLQSSGPHSLAYTHLIVIRHGETAWNRERRLQGQLDIPLNETGEAQARALAAALA
CCCCCCCCCCCCCCEEEEEEEEEECCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHC
GEPIDAVYSSDLGRAMQTAAPLAETLGLKVRSEPRLRERSYGTLQGMTYAEVAEKLPEDF
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHCCCCHHHHHHHHHHHH
ARWQARVPDYTPPQGESLAQFHERAVEIALSLSRRHPGERIALVAHGGVLDCLYREATGM
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCC
TLEAPRQHELLNASINRLRSDSHHLTLAQWGDVTHLETLALDEVDRRVP
EECCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQGKGMLQSSGPHSLAYTHLIVIRHGETAWNRERRLQGQLDIPLNETGEAQARALAAALA
CCCCCCCCCCCCCCEEEEEEEEEECCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHC
GEPIDAVYSSDLGRAMQTAAPLAETLGLKVRSEPRLRERSYGTLQGMTYAEVAEKLPEDF
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHCCCCHHHHHHHHHHHH
ARWQARVPDYTPPQGESLAQFHERAVEIALSLSRRHPGERIALVAHGGVLDCLYREATGM
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCC
TLEAPRQHELLNASINRLRSDSHHLTLAQWGDVTHLETLALDEVDRRVP
EECCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]