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The map label for this gene is ttuD [H]

Identifier: 73540169

GI number: 73540169

Start: 508941

End: 510254

Strand: Direct

Name: ttuD [H]

Synonym: Reut_A0463

Alternate gene names: 73540169

Gene position: 508941-510254 (Clockwise)

Preceding gene: 73540168

Following gene: 73540170

Centisome position: 13.37

GC content: 68.49

Gene sequence:

>1314_bases
GTGAGCGCGCCGGGGAGTTTCACGGGCGATCCGCGCGCGCTGCTGCTCGAGACGTTCCAGGCGGCGGTGGCGGCGGCGGA
TCCGCTGAAGATCGTGGCCGAGTACTTGCCGCCGCCACAGCCGGGAGGGCGTACGCTGGTCGTGGGCGCGGGCAAGGCCG
CGGCGTCGATGGCGCTGGCGGCGGAGCAAGCCTATGCCGGCAAGGCGCAGGTCGAAGGGCTGGTCGTCACGCGCTACGCG
CATGGCCTGCCCACACAGCACGTGCGCGTGATCGAGGCCGGCCATCCCGTTCCTGATGAGGCGGGCGAGCAGGCCGCAGC
GGACATTCTGACCAGCGTGTCATCGCTGACGCCCGCGGACCGCCTGCTGGTGCTGGTGTCCGGCGGCGGATCGAGCCTGC
TGTCGCTGCCTGCCGAAGGTATTCCAATGGCGGACCTCAAGGCCACCACGAAGGAACTGCTGCGCTGCGGGGCGCCGATC
ACAGAGATGAATATCGTGCGCAAGCACATCTCGCGCATCCAGGGCGGGCGTCTGGCGCAGGCCAGCCAGGCGCCGGTGAC
GACGTTGATTGTCTCGGACGTGGCCGGCGACGATCCCAGTGCGATCGCTTCGGGGCCAACGGTAGCGGATCCCAGCACGT
TCGCGGACGCGCTGGATATCCTGCGCCGTTACGGCGCGACGGTGCCGGCCAGCGTCCAGTCGCACCTTGAGCGCGGCGCG
CGCGGTGAGGTGGCCGAGACGCCCAAGCCGGGCGATCCCCTGTTCGCGCGCGTCGACAACCGCATGATCGCTACCGCACA
CGGTAGCCTGCAGGCGGCTGCGGCGCTGTTCCACGAACGCGGCATCACCCCGGTGATCCTCGGCGATACGGTAACGGGCG
AAGCGCAGGAAGTTGCGCGCGTCTATGCCGCGCTGGTGCGTGAGATTCGCGCGTACAATGCGCCGTTTGCCGCGCCGGTT
GCACTGATTTCTGGCGGTGAATGCACGGTCACATTGCCGGCCGGTGGTGGCAGCAGCAAGGCCCGGGGAGGGCGTTGTTC
GGAATTCCTGCTGTCGCTGGCGATCGAACTGGCTGGCATGGAAGGTGTGTACGCCATTGCCGCCGACACCGACGGTATAG
ACGGTTCCGAGGACAATGCGGGTGCACTGGCCGATCCGACGACCCTGGCGCGAGCGGATGCGGCAGGCGTGCCGGCCCGG
CGCCAGCTCGATGCGCACGATGCCTGGGGTCTGTTCGATGCGGTAGGCGACCTGGTCGTGACCGGCCCGACGCGCACCAA
TGTGAACGATTACCGCGCCATCCTGATTCTCTAA

Upstream 100 bases:

>100_bases
AGAAGGTGTTGTCCGAGGGCCCCGACCATGCGCCGCTGACGCGCGATATCGGCGGCAAGGCGGGCACCGAGGACCTGGGC
CGCGCAATCGCGGAGGCGCT

Downstream 100 bases:

>100_bases
CTTTCAGTACGCCTGCCGGCATGCGGCGGCAGGCCCAGCAACCATGACTCAGAAGCTCACCATCACCCGCCCGGACGACT
GGCACCTGCACCTGCGCGAC

Product: hydroxypyruvate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MSAPGSFTGDPRALLLETFQAAVAAADPLKIVAEYLPPPQPGGRTLVVGAGKAAASMALAAEQAYAGKAQVEGLVVTRYA
HGLPTQHVRVIEAGHPVPDEAGEQAAADILTSVSSLTPADRLLVLVSGGGSSLLSLPAEGIPMADLKATTKELLRCGAPI
TEMNIVRKHISRIQGGRLAQASQAPVTTLIVSDVAGDDPSAIASGPTVADPSTFADALDILRRYGATVPASVQSHLERGA
RGEVAETPKPGDPLFARVDNRMIATAHGSLQAAAALFHERGITPVILGDTVTGEAQEVARVYAALVREIRAYNAPFAAPV
ALISGGECTVTLPAGGGSSKARGGRCSEFLLSLAIELAGMEGVYAIAADTDGIDGSEDNAGALADPTTLARADAAGVPAR
RQLDAHDAWGLFDAVGDLVVTGPTRTNVNDYRAILIL

Sequences:

>Translated_437_residues
MSAPGSFTGDPRALLLETFQAAVAAADPLKIVAEYLPPPQPGGRTLVVGAGKAAASMALAAEQAYAGKAQVEGLVVTRYA
HGLPTQHVRVIEAGHPVPDEAGEQAAADILTSVSSLTPADRLLVLVSGGGSSLLSLPAEGIPMADLKATTKELLRCGAPI
TEMNIVRKHISRIQGGRLAQASQAPVTTLIVSDVAGDDPSAIASGPTVADPSTFADALDILRRYGATVPASVQSHLERGA
RGEVAETPKPGDPLFARVDNRMIATAHGSLQAAAALFHERGITPVILGDTVTGEAQEVARVYAALVREIRAYNAPFAAPV
ALISGGECTVTLPAGGGSSKARGGRCSEFLLSLAIELAGMEGVYAIAADTDGIDGSEDNAGALADPTTLARADAAGVPAR
RQLDAHDAWGLFDAVGDLVVTGPTRTNVNDYRAILIL
>Mature_436_residues
SAPGSFTGDPRALLLETFQAAVAAADPLKIVAEYLPPPQPGGRTLVVGAGKAAASMALAAEQAYAGKAQVEGLVVTRYAH
GLPTQHVRVIEAGHPVPDEAGEQAAADILTSVSSLTPADRLLVLVSGGGSSLLSLPAEGIPMADLKATTKELLRCGAPIT
EMNIVRKHISRIQGGRLAQASQAPVTTLIVSDVAGDDPSAIASGPTVADPSTFADALDILRRYGATVPASVQSHLERGAR
GEVAETPKPGDPLFARVDNRMIATAHGSLQAAAALFHERGITPVILGDTVTGEAQEVARVYAALVREIRAYNAPFAAPVA
LISGGECTVTLPAGGGSSKARGGRCSEFLLSLAIELAGMEGVYAIAADTDGIDGSEDNAGALADPTTLARADAAGVPARR
QLDAHDAWGLFDAVGDLVVTGPTRTNVNDYRAILIL

Specific function: Degrades an unidentified toxic product from the first step of tartrate degradation [H]

COG id: COG2379

COG function: function code G; Putative glycerate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31543063, Length=494, Percent_Identity=31.7813765182186, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI193205461, Length=452, Percent_Identity=26.5486725663717, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI19920578, Length=491, Percent_Identity=28.5132382892057, Blast_Score=114, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007835 [H]

Pfam domain/function: PF05161 MOFRL [H]

EC number: =1.1.1.81 [H]

Molecular weight: Translated: 44670; Mature: 44539

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPGSFTGDPRALLLETFQAAVAAADPLKIVAEYLPPPQPGGRTLVVGAGKAAASMALA
CCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHH
AEQAYAGKAQVEGLVVTRYAHGLPTQHVRVIEAGHPVPDEAGEQAAADILTSVSSLTPAD
HHHHHCCCHHHCEEEEEEHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCC
RLLVLVSGGGSSLLSLPAEGIPMADLKATTKELLRCGAPITEMNIVRKHISRIQGGRLAQ
EEEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCC
ASQAPVTTLIVSDVAGDDPSAIASGPTVADPSTFADALDILRRYGATVPASVQSHLERGA
CCCCCEEEEEEECCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
RGEVAETPKPGDPLFARVDNRMIATAHGSLQAAAALFHERGITPVILGDTVTGEAQEVAR
CCCCCCCCCCCCCCEEECCCEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHH
VYAALVREIRAYNAPFAAPVALISGGECTVTLPAGGGSSKARGGRCSEFLLSLAIELAGM
HHHHHHHHHHHCCCCCCCCEEEEECCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCC
EGVYAIAADTDGIDGSEDNAGALADPTTLARADAAGVPARRQLDAHDAWGLFDAVGDLVV
CCEEEEEECCCCCCCCCCCCCCCCCCHHHHHCCCCCCCHHHCCCCCHHHHHHHHHCCEEE
TGPTRTNVNDYRAILIL
ECCCCCCCCCCEEEEEC
>Mature Secondary Structure 
SAPGSFTGDPRALLLETFQAAVAAADPLKIVAEYLPPPQPGGRTLVVGAGKAAASMALA
CCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHH
AEQAYAGKAQVEGLVVTRYAHGLPTQHVRVIEAGHPVPDEAGEQAAADILTSVSSLTPAD
HHHHHCCCHHHCEEEEEEHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCC
RLLVLVSGGGSSLLSLPAEGIPMADLKATTKELLRCGAPITEMNIVRKHISRIQGGRLAQ
EEEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCC
ASQAPVTTLIVSDVAGDDPSAIASGPTVADPSTFADALDILRRYGATVPASVQSHLERGA
CCCCCEEEEEEECCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
RGEVAETPKPGDPLFARVDNRMIATAHGSLQAAAALFHERGITPVILGDTVTGEAQEVAR
CCCCCCCCCCCCCCEEECCCEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHH
VYAALVREIRAYNAPFAAPVALISGGECTVTLPAGGGSSKARGGRCSEFLLSLAIELAGM
HHHHHHHHHHHCCCCCCCCEEEEECCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCC
EGVYAIAADTDGIDGSEDNAGALADPTTLARADAAGVPARRQLDAHDAWGLFDAVGDLVV
CCEEEEEECCCCCCCCCCCCCCCCCCHHHHHCCCCCCCHHHCCCCCHHHHHHHHHCCEEE
TGPTRTNVNDYRAILIL
ECCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]