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The map label for this gene is gltK [H]

Identifier: 73540165

GI number: 73540165

Start: 505423

End: 506106

Strand: Direct

Name: gltK [H]

Synonym: Reut_A0459

Alternate gene names: 73540165

Gene position: 505423-506106 (Clockwise)

Preceding gene: 73540164

Following gene: 73540166

Centisome position: 13.28

GC content: 60.38

Gene sequence:

>684_bases
ATGGCATACGAATTCGACTTCAGTTCCATCACGCCGGCCACGCTGGAGGTGTTGGGCGAGGGCATGCTGGTCTCGCTCAA
GATCACGGTCACGGCCATCATCGTCGGCATTGTCTGGGGCACCATCCTGGCGATGATGCGGCTGTCGTCCGTCAAGCCGC
TGAACTGGTTCGCGCAGGGGTACGTGACCATCTTCCGCTCCATCCCGCTGGTGATGGTGCTGCTGTGGTTCTTCCTGATC
ATCCCGCAGGTGCTGCAGAACATCTTCAACCTGTCGCCGGCATCGGATCTGCGCATGACCTCGGCCCTGATCGCCTTTTC
GCTGTTCGAGGCGGCTTACTATTCCGAGATCATCCGGGCCGGTATCCAGAGCGTGTCGCGCGGGCAGATGTTCGCGGCAC
AGGCGCTGGGCATGACCTACGGTCAGACCATGAAGCTGGTCATCCTGCCGCAGGCGTTCCGCAACATGGTGCCGCTGCTG
CTGACGCAGGGCATCATCCTGTTCCAGGATACGTCGCTGGTCTACGTGAGCGCGCTGGCGGACTTCTTCGGCCAGGCCTA
TGGCGTGGGCGAGCGTGACGGCCGCATTGTCGAAATGCTGCTGTTCGCCGGCCTCGTGTATTTTGTTATCTGCTACTCCG
TTTCGCTGATGGTCAAGCGTTACCAGAAAAAGGTGGCCCTATGA

Upstream 100 bases:

>100_bases
GATGTACGCGCTCATCAATATCGTCGTCATGCTGGTCATGCGCTGGGTCGAAGCCCGCAGCCGCGTACCCGGCTTTATCG
GCAGCAAGTAAGGGGGCGCC

Downstream 100 bases:

>100_bases
TTGAAATCAATAATGTTTCCAAGTGGTATGGCTCCTTCCAGGTGCTGACCGACTGCACCACCAGGGTTGCCAAGGGCGAA
GTCGTGGTGGTCTGCGGCCC

Product: amino acid ABC transporter permease

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MAYEFDFSSITPATLEVLGEGMLVSLKITVTAIIVGIVWGTILAMMRLSSVKPLNWFAQGYVTIFRSIPLVMVLLWFFLI
IPQVLQNIFNLSPASDLRMTSALIAFSLFEAAYYSEIIRAGIQSVSRGQMFAAQALGMTYGQTMKLVILPQAFRNMVPLL
LTQGIILFQDTSLVYVSALADFFGQAYGVGERDGRIVEMLLFAGLVYFVICYSVSLMVKRYQKKVAL

Sequences:

>Translated_227_residues
MAYEFDFSSITPATLEVLGEGMLVSLKITVTAIIVGIVWGTILAMMRLSSVKPLNWFAQGYVTIFRSIPLVMVLLWFFLI
IPQVLQNIFNLSPASDLRMTSALIAFSLFEAAYYSEIIRAGIQSVSRGQMFAAQALGMTYGQTMKLVILPQAFRNMVPLL
LTQGIILFQDTSLVYVSALADFFGQAYGVGERDGRIVEMLLFAGLVYFVICYSVSLMVKRYQKKVAL
>Mature_226_residues
AYEFDFSSITPATLEVLGEGMLVSLKITVTAIIVGIVWGTILAMMRLSSVKPLNWFAQGYVTIFRSIPLVMVLLWFFLII
PQVLQNIFNLSPASDLRMTSALIAFSLFEAAYYSEIIRAGIQSVSRGQMFAAQALGMTYGQTMKLVILPQAFRNMVPLLL
TQGIILFQDTSLVYVSALADFFGQAYGVGERDGRIVEMLLFAGLVYFVICYSVSLMVKRYQKKVAL

Specific function: Part of the binding-protein-dependent transport system for aspartate/glutamate; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786873, Length=224, Percent_Identity=67.4107142857143, Blast_Score=310, Evalue=7e-86,
Organism=Escherichia coli, GI1788226, Length=212, Percent_Identity=34.9056603773585, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87082239, Length=207, Percent_Identity=32.3671497584541, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1787030, Length=227, Percent_Identity=29.0748898678414, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1786874, Length=213, Percent_Identity=27.2300469483568, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1787087, Length=221, Percent_Identity=27.1493212669683, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787086, Length=214, Percent_Identity=28.0373831775701, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI48994930, Length=125, Percent_Identity=33.6, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788645, Length=206, Percent_Identity=24.2718446601942, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788646, Length=165, Percent_Identity=24.2424242424242, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 25278; Mature: 25146

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYEFDFSSITPATLEVLGEGMLVSLKITVTAIIVGIVWGTILAMMRLSSVKPLNWFAQG
CCEECCCCCCCHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
YVTIFRSIPLVMVLLWFFLIIPQVLQNIFNLSPASDLRMTSALIAFSLFEAAYYSEIIRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GIQSVSRGQMFAAQALGMTYGQTMKLVILPQAFRNMVPLLLTQGIILFQDTSLVYVSALA
HHHHHHHHHHHHHHHHHHHHCCHHEEEEEHHHHHHHHHHHHHCCCCEEECCHHHHHHHHH
DFFGQAYGVGERDGRIVEMLLFAGLVYFVICYSVSLMVKRYQKKVAL
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AYEFDFSSITPATLEVLGEGMLVSLKITVTAIIVGIVWGTILAMMRLSSVKPLNWFAQG
CEECCCCCCCHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
YVTIFRSIPLVMVLLWFFLIIPQVLQNIFNLSPASDLRMTSALIAFSLFEAAYYSEIIRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GIQSVSRGQMFAAQALGMTYGQTMKLVILPQAFRNMVPLLLTQGIILFQDTSLVYVSALA
HHHHHHHHHHHHHHHHHHHHCCHHEEEEEHHHHHHHHHHHHHCCCCEEECCHHHHHHHHH
DFFGQAYGVGERDGRIVEMLLFAGLVYFVICYSVSLMVKRYQKKVAL
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]