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The map label for this gene is ompR [H]

Identifier: 73540096

GI number: 73540096

Start: 427540

End: 428253

Strand: Direct

Name: ompR [H]

Synonym: Reut_A0390

Alternate gene names: 73540096

Gene position: 427540-428253 (Clockwise)

Preceding gene: 73540095

Following gene: 73540097

Centisome position: 11.23

GC content: 65.27

Gene sequence:

>714_bases
ATGGAGCAGGTGAACAGGATTATCGTGCTCGACGACGAAGCCGAGCTGCGCAATATGCTGCAACGGTTCCTGACGGACCA
TGGCTTCCGCGTGCGTGCGGTGGCCGATGGCAAGCAACTCGACCGCCACCTGCAGCGCGAGCCCCATGACCTGCTGGTGC
TGGACCTGATGATGGAACCTGAAGACGGCCTCACCATCTGCCGCCGCCTGCGTGCCGAAGGGCATACGCTGCCGATCCTG
ATGCTGACCGCGAAGGGCGACCCGATGGACCGCGTCGCCGGTCTGGAAACCGGTGCCGACGACTACCTGGCCAAGCCCTT
TGTCCCGGACGAACTGGTGGCGCGCATCCGTGCCCTGCTGCGTCGCCAGAAGATGGCCGCGGGCGATCCCACGGTCACCA
CGCAGACACTGCGCTTTGGTGACTTCACCTTCGATGTCGGCAAGCAGACTCTCACGCGCAGCGGCGAGCCCGTGGAAGTC
CATTCCGCTCAGATGCTGCTGCTGCATGCGCTCGGTTCGTCGCCCAATCGCGCCGTGAGCCGCGACAACCTGCTCGCGCG
GGCACGCGGGCGCGACCATGACGCGCTCGACCGCAGCATCGACGTGCAGATCCTGCGCCTGCGCCAGATCGTCGAGGACG
ATCCGTCCAAGCCGCGCTTCATCAAGACCGTTTGGGGAATCGGTTACATGCTGGTGGCCGGCGTCGAATCGTGA

Upstream 100 bases:

>100_bases
GCAACGGCTCCATTACGCTGCCGCAGATCGAGGCGTTCATGACGCAGGAAATGATGTCGCGCAGAGGTGGTTGAGACCAC
AACGATGCCGGAGGCTCGCG

Downstream 100 bases:

>100_bases
TGCGGATCGGGCTGCCGCGTTCGCTGCTGGCGCGCAATATCGCGCTGCTGCTCGCGCTGGTGGCGCTCACGCAGGCGTGT
TCGCTCACCGTGCTGCTGCA

Product: response regulator receiver:transcriptional regulatory protein, C-terminal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MEQVNRIIVLDDEAELRNMLQRFLTDHGFRVRAVADGKQLDRHLQREPHDLLVLDLMMEPEDGLTICRRLRAEGHTLPIL
MLTAKGDPMDRVAGLETGADDYLAKPFVPDELVARIRALLRRQKMAAGDPTVTTQTLRFGDFTFDVGKQTLTRSGEPVEV
HSAQMLLLHALGSSPNRAVSRDNLLARARGRDHDALDRSIDVQILRLRQIVEDDPSKPRFIKTVWGIGYMLVAGVES

Sequences:

>Translated_237_residues
MEQVNRIIVLDDEAELRNMLQRFLTDHGFRVRAVADGKQLDRHLQREPHDLLVLDLMMEPEDGLTICRRLRAEGHTLPIL
MLTAKGDPMDRVAGLETGADDYLAKPFVPDELVARIRALLRRQKMAAGDPTVTTQTLRFGDFTFDVGKQTLTRSGEPVEV
HSAQMLLLHALGSSPNRAVSRDNLLARARGRDHDALDRSIDVQILRLRQIVEDDPSKPRFIKTVWGIGYMLVAGVES
>Mature_237_residues
MEQVNRIIVLDDEAELRNMLQRFLTDHGFRVRAVADGKQLDRHLQREPHDLLVLDLMMEPEDGLTICRRLRAEGHTLPIL
MLTAKGDPMDRVAGLETGADDYLAKPFVPDELVARIRALLRRQKMAAGDPTVTTQTLRFGDFTFDVGKQTLTRSGEPVEV
HSAQMLLLHALGSSPNRAVSRDNLLARARGRDHDALDRSIDVQILRLRQIVEDDPSKPRFIKTVWGIGYMLVAGVES

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=233, Percent_Identity=51.0729613733906, Blast_Score=249, Evalue=9e-68,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=37.6106194690265, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1788394, Length=235, Percent_Identity=33.6170212765957, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=35.1931330472103, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI2367329, Length=238, Percent_Identity=37.3949579831933, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=34.070796460177, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=34.070796460177, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=35.042735042735, Blast_Score=120, Evalue=5e-29,
Organism=Escherichia coli, GI1790863, Length=237, Percent_Identity=29.1139240506329, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1790552, Length=232, Percent_Identity=34.051724137931, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=32.6086956521739, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=31.4159292035398, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1786911, Length=231, Percent_Identity=32.9004329004329, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=31.140350877193, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1788550, Length=126, Percent_Identity=31.7460317460317, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790437, Length=135, Percent_Identity=31.8518518518519, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790299, Length=119, Percent_Identity=31.9327731092437, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26706; Mature: 26706

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQVNRIIVLDDEAELRNMLQRFLTDHGFRVRAVADGKQLDRHLQREPHDLLVLDLMMEP
CCCCCEEEEECCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCCEEEEEEEECC
EDGLTICRRLRAEGHTLPILMLTAKGDPMDRVAGLETGADDYLAKPFVPDELVARIRALL
CCHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHCCCCCCCHHHCCCCCCHHHHHHHHHHH
RRQKMAAGDPTVTTQTLRFGDFTFDVGKQTLTRSGEPVEVHSAQMLLLHALGSSPNRAVS
HHHHHCCCCCCEEEEEEEECCEEHHHCHHHHHCCCCCEEHHHHHHHHHHHHCCCCCCCHH
RDNLLARARGRDHDALDRSIDVQILRLRQIVEDDPSKPRFIKTVWGIGYMLVAGVES
HHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEQVNRIIVLDDEAELRNMLQRFLTDHGFRVRAVADGKQLDRHLQREPHDLLVLDLMMEP
CCCCCEEEEECCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCCEEEEEEEECC
EDGLTICRRLRAEGHTLPILMLTAKGDPMDRVAGLETGADDYLAKPFVPDELVARIRALL
CCHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHCCCCCCCHHHCCCCCCHHHHHHHHHHH
RRQKMAAGDPTVTTQTLRFGDFTFDVGKQTLTRSGEPVEVHSAQMLLLHALGSSPNRAVS
HHHHHCCCCCCEEEEEEEECCEEHHHCHHHHHCCCCCEEHHHHHHHHHHHHCCCCCCCHH
RDNLLARARGRDHDALDRSIDVQILRLRQIVEDDPSKPRFIKTVWGIGYMLVAGVES
HHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]