Click here to switch to the map view.

The map label for this gene is hprK [H]

Identifier: 73540058

GI number: 73540058

Start: 382338

End: 383309

Strand: Reverse

Name: hprK [H]

Synonym: Reut_A0352

Alternate gene names: 73540058

Gene position: 383309-382338 (Counterclockwise)

Preceding gene: 73540059

Following gene: 73540057

Centisome position: 10.07

GC content: 65.43

Gene sequence:

>972_bases
ATGGAACTCACCGGCGTCACCTCGCAGTCGATCTTCGACGACAACGCAGCCGACATCAAACTCTCGTGGGTGGCTGGCCT
GGAAGGTGCGGACCGCGCCTTCGACGTGGAGTTTGCCCGCGAGGCCACCTCGGCCGCGGACCTCGTCGGCCACCTGAACC
TGATCCACCCGAACCGGATCCAGGTCCTCGGCAAGCCCGAAATCACGTACTACCAGCGCCTGGACGACGAAACCCGCAAG
CGCCAGATGGGCGAGCTGATCCTGCTGGAGCCGCCGTTCCTCGTTGTGGCCGACGGCATGGAGCCGCCGCCGGACCTGGA
ACTGCGCTGCACGCGTTCGTCCACGCCACTGTTCACCACGCCGGTGTCGTCCGCAGCGGTAATCGACCACCTGCGGTTGT
ACCTGTCGCGCATTTCCGCGCCGCGCGTGACCATGCACGGCGTGTTTCTCGACATTCTCGGCATGGGCGTGCTGATCATG
GGCGAGTCGGGCCTGGGCAAGAGCGAACTGGGCCTGGAACTGATTTCGCGCGGCCACGGACTGGTAGCCGACGATGCCGT
GGATTTCGTGCGCCTTGGGCCGGATTTCATCGAAGGACGCTGCCCGCCGCTGCTCCAGAACCTGCTGGAAGTGCGCGGCC
TGGGCCTGCTCGACATCAAGACCATCTTCGGTGAAACCGCCGTGCGTCGGAAAATGAAGATGAAGCTGGTCGTGCAGCTT
GTGCGCCGCAACGACGGCGAATTCGAACGTCTGCCGCTCGATTCGCAGTACCTCGACGTACTTGGCCTGCCGATCCACAT
GGTCAAGATCCAGGTCGCGGCCGGCCGAAACCTCGCCGTGCTGGTCGAGGCTGCCGTGCGCAACACGATCCTGCGCCTGC
GCGGCATCGACACGCTGCGCGACTTCATGGACCGCCAGCGCGCTGCCATGCAGGCCGACGCAGTTTCGCGCGGCCAGGGC
CGCCTGCTCTGA

Upstream 100 bases:

>100_bases
AGCTACTGACACAGTGGCATCCCTGACCCTTCCCCTGGGCTGGCAACAGACCGGACGACCCTAAAGCCCGGCACTGCCCC
CGCCCCGAAAGTCATACCGC

Downstream 100 bases:

>100_bases
CCCGGCATCGCGACTCGCTTTCAATTGCTTACATCGACGTTGGCAAATCGGTCAACGCGGTGGGTACATGCTTCGTTTTG
TGCTGTAATGGGCATCGAGC

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MELTGVTSQSIFDDNAADIKLSWVAGLEGADRAFDVEFAREATSAADLVGHLNLIHPNRIQVLGKPEITYYQRLDDETRK
RQMGELILLEPPFLVVADGMEPPPDLELRCTRSSTPLFTTPVSSAAVIDHLRLYLSRISAPRVTMHGVFLDILGMGVLIM
GESGLGKSELGLELISRGHGLVADDAVDFVRLGPDFIEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKMKLVVQL
VRRNDGEFERLPLDSQYLDVLGLPIHMVKIQVAAGRNLAVLVEAAVRNTILRLRGIDTLRDFMDRQRAAMQADAVSRGQG
RLL

Sequences:

>Translated_323_residues
MELTGVTSQSIFDDNAADIKLSWVAGLEGADRAFDVEFAREATSAADLVGHLNLIHPNRIQVLGKPEITYYQRLDDETRK
RQMGELILLEPPFLVVADGMEPPPDLELRCTRSSTPLFTTPVSSAAVIDHLRLYLSRISAPRVTMHGVFLDILGMGVLIM
GESGLGKSELGLELISRGHGLVADDAVDFVRLGPDFIEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKMKLVVQL
VRRNDGEFERLPLDSQYLDVLGLPIHMVKIQVAAGRNLAVLVEAAVRNTILRLRGIDTLRDFMDRQRAAMQADAVSRGQG
RLL
>Mature_323_residues
MELTGVTSQSIFDDNAADIKLSWVAGLEGADRAFDVEFAREATSAADLVGHLNLIHPNRIQVLGKPEITYYQRLDDETRK
RQMGELILLEPPFLVVADGMEPPPDLELRCTRSSTPLFTTPVSSAAVIDHLRLYLSRISAPRVTMHGVFLDILGMGVLIM
GESGLGKSELGLELISRGHGLVADDAVDFVRLGPDFIEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKMKLVVQL
VRRNDGEFERLPLDSQYLDVLGLPIHMVKIQVAAGRNLAVLVEAAVRNTILRLRGIDTLRDFMDRQRAAMQADAVSRGQG
RLL

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126 [H]

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N [H]

EC number: NA

Molecular weight: Translated: 35696; Mature: 35696

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELTGVTSQSIFDDNAADIKLSWVAGLEGADRAFDVEFAREATSAADLVGHLNLIHPNRI
CCCCCCCCHHHCCCCCCCEEEEEEECCCCCCCEECHHHHHHHHHHHHHHHHHEEECCCEE
QVLGKPEITYYQRLDDETRKRQMGELILLEPPFLVVADGMEPPPDLELRCTRSSTPLFTT
EEECCCCCHHHHHCCHHHHHHHHCCEEEECCCEEEEECCCCCCCCCEEEEECCCCCEEEC
PVSSAAVIDHLRLYLSRISAPRVTMHGVFLDILGMGVLIMGESGLGKSELGLELISRGHG
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHCCCC
LVADDAVDFVRLGPDFIEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKMKLVVQL
CEEHHHHHHHHCCCHHHCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHH
VRRNDGEFERLPLDSQYLDVLGLPIHMVKIQVAAGRNLAVLVEAAVRNTILRLRGIDTLR
HHCCCCCEEECCCCHHHHHHHCCCEEEEEEEEECCCCEEEEHHHHHHHHHHHHCCHHHHH
DFMDRQRAAMQADAVSRGQGRLL
HHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MELTGVTSQSIFDDNAADIKLSWVAGLEGADRAFDVEFAREATSAADLVGHLNLIHPNRI
CCCCCCCCHHHCCCCCCCEEEEEEECCCCCCCEECHHHHHHHHHHHHHHHHHEEECCCEE
QVLGKPEITYYQRLDDETRKRQMGELILLEPPFLVVADGMEPPPDLELRCTRSSTPLFTT
EEECCCCCHHHHHCCHHHHHHHHCCEEEECCCEEEEECCCCCCCCCEEEEECCCCCEEEC
PVSSAAVIDHLRLYLSRISAPRVTMHGVFLDILGMGVLIMGESGLGKSELGLELISRGHG
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHCCCC
LVADDAVDFVRLGPDFIEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKMKLVVQL
CEEHHHHHHHHCCCHHHCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHH
VRRNDGEFERLPLDSQYLDVLGLPIHMVKIQVAAGRNLAVLVEAAVRNTILRLRGIDTLR
HHCCCCCEEECCCCHHHHHHHCCCEEEEEEEEECCCCEEEEHHHHHHHHHHHHCCHHHHH
DFMDRQRAAMQADAVSRGQGRLL
HHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA