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The map label for this gene is bioC [H]

Identifier: 73540018

GI number: 73540018

Start: 342755

End: 343756

Strand: Direct

Name: bioC [H]

Synonym: Reut_A0312

Alternate gene names: 73540018

Gene position: 342755-343756 (Clockwise)

Preceding gene: 73540015

Following gene: 73540019

Centisome position: 9.0

GC content: 67.66

Gene sequence:

>1002_bases
ATGCGCCATCAATATTGCCGCGCCTTCCTTGTCTTCCTGTTGCCTGGTTTTCCCGTGTCCCTGCATGCCGCCGATTCTCC
CGATGCTTTCGTGCCGCCCACGCGGCTGACCCGGATCGCCTTCGACCGGCGCAGCGCCGCGTTCGGCCAGCTCGATTTCT
TGCTTGGCGAGATCGGCCGCCGCATGCAGGAACGCATGGAGGTGGTCCGGCTGACGCCACAGCGCGCGCTGGACATCGGC
TGCGGACACGGCCAGGGCCTGGCCGGCCTGCGCGCGCGCTTTCCCGATGCACAGATTGCCGGCCTCGATATTTCCGGCGT
GATGCTGGCCGAAGCGGGCCAGCGCGATCCTCAACGGCGGCCCGGCTGGGTCGGCCGCTTGCTCGGCAAGCGCCCGCTGT
TCGATCTGGTCCAGGGCGATCTTGCCACACTGCCTTTTGCGCCCGGCAGCTTCGACCTGCTGTGGTCCAACCTGGCGCTG
CACTGGCATCCGGAGCCGCATCGCGTGTTCCCGGAGTGGCACCGCGTGACGCGCGACGATGGCCTCGTGATGTTCTCGCT
GTTCGGCCCCGATACGCTGCGCGAACTGCGCACGGCGTTCGAGGAAGTCGATACCGCGACCCACACGTTGCGCTTTGTCG
ACATGCACGATATCGGCGACATGCTGGTACATGGTGGATGGTCCACGCCGGTGATGGACATGGAAACGCTCACCGTGACC
TATGAATCGCCCGAGATGCTGCTGCGCGAGGTGCAAGCCTTCGGCGGCCTGCGCGCGCATCCGGCCCTGCGGCGTGCCGG
CCTGCATGGCCGGCGCTGGCATCAGGCGGTGTGCGCGGCGCTTGAGCGCCTGCGCAATGCCGATGGCGTGATTCCGCTGA
CCTTCGAAATCGTCTACGGCCACGCCTGGAAGCTGCCCCCGCGTGGTGCGCAGCAGGTGGACGAACTTGGCCGCGCGGTC
GTGCCGCTGGACAAGATCGGCCGGGCCAGGCCCCGCCGCTGA

Upstream 100 bases:

>100_bases
ATGGCAGCAGCTTGCGCATCAGCCCGCGGACCTGTCCGGCGGCTTTCGCGGTGCGCGCGTATACTTGCCGTCCAGTCGTC
CGCCATGGCGCGCGGCTGCC

Downstream 100 bases:

>100_bases
GCAGTTACGACTGTAATGACTTCCGCGTAACGAAAACACGCGCGGATCGCCCGCGAGGCCGCGTCTGCACTGGCTTTGCG
GGCGATCTCGTTAATGCGCG

Product: putative methylase involved in ubiquinone/menaquinone biosynthesis

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MRHQYCRAFLVFLLPGFPVSLHAADSPDAFVPPTRLTRIAFDRRSAAFGQLDFLLGEIGRRMQERMEVVRLTPQRALDIG
CGHGQGLAGLRARFPDAQIAGLDISGVMLAEAGQRDPQRRPGWVGRLLGKRPLFDLVQGDLATLPFAPGSFDLLWSNLAL
HWHPEPHRVFPEWHRVTRDDGLVMFSLFGPDTLRELRTAFEEVDTATHTLRFVDMHDIGDMLVHGGWSTPVMDMETLTVT
YESPEMLLREVQAFGGLRAHPALRRAGLHGRRWHQAVCAALERLRNADGVIPLTFEIVYGHAWKLPPRGAQQVDELGRAV
VPLDKIGRARPRR

Sequences:

>Translated_333_residues
MRHQYCRAFLVFLLPGFPVSLHAADSPDAFVPPTRLTRIAFDRRSAAFGQLDFLLGEIGRRMQERMEVVRLTPQRALDIG
CGHGQGLAGLRARFPDAQIAGLDISGVMLAEAGQRDPQRRPGWVGRLLGKRPLFDLVQGDLATLPFAPGSFDLLWSNLAL
HWHPEPHRVFPEWHRVTRDDGLVMFSLFGPDTLRELRTAFEEVDTATHTLRFVDMHDIGDMLVHGGWSTPVMDMETLTVT
YESPEMLLREVQAFGGLRAHPALRRAGLHGRRWHQAVCAALERLRNADGVIPLTFEIVYGHAWKLPPRGAQQVDELGRAV
VPLDKIGRARPRR
>Mature_333_residues
MRHQYCRAFLVFLLPGFPVSLHAADSPDAFVPPTRLTRIAFDRRSAAFGQLDFLLGEIGRRMQERMEVVRLTPQRALDIG
CGHGQGLAGLRARFPDAQIAGLDISGVMLAEAGQRDPQRRPGWVGRLLGKRPLFDLVQGDLATLPFAPGSFDLLWSNLAL
HWHPEPHRVFPEWHRVTRDDGLVMFSLFGPDTLRELRTAFEEVDTATHTLRFVDMHDIGDMLVHGGWSTPVMDMETLTVT
YESPEMLLREVQAFGGLRAHPALRRAGLHGRRWHQAVCAALERLRNADGVIPLTFEIVYGHAWKLPPRGAQQVDELGRAV
VPLDKIGRARPRR

Specific function: BioC is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

Organism=Homo sapiens, GI40018642, Length=286, Percent_Identity=27.6223776223776, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI86792933, Length=285, Percent_Identity=24.9122807017544, Blast_Score=82, Evalue=7e-16,
Organism=Escherichia coli, GI1786994, Length=243, Percent_Identity=28.8065843621399, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17535003, Length=298, Percent_Identity=26.8456375838926, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI19922210, Length=292, Percent_Identity=29.4520547945205, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011814
- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 37468; Mature: 37468

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHQYCRAFLVFLLPGFPVSLHAADSPDAFVPPTRLTRIAFDRRSAAFGQLDFLLGEIGR
CCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMQERMEVVRLTPQRALDIGCGHGQGLAGLRARFPDAQIAGLDISGVMLAEAGQRDPQRR
HHHHHHHHHHCCHHHHHCCCCCCCCCCCHHHHCCCCCEEECCCCCCCCEECCCCCCCCCC
PGWVGRLLGKRPLFDLVQGDLATLPFAPGSFDLLWSNLALHWHPEPHRVFPEWHRVTRDD
CCHHHHHHCCCHHHHHHCCCHHCCCCCCCCHHHHHHCCEEEECCCCCCCCHHHHHHCCCC
GLVMFSLFGPDTLRELRTAFEEVDTATHTLRFVDMHDIGDMLVHGGWSTPVMDMETLTVT
CEEEEEECCCHHHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHEECCCCCCCEEEEEEEEE
YESPEMLLREVQAFGGLRAHPALRRAGLHGRRWHQAVCAALERLRNADGVIPLTFEIVYG
ECCHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEC
HAWKLPPRGAQQVDELGRAVVPLDKIGRARPRR
CEECCCCCCHHHHHHHCCEECCHHHHCCCCCCC
>Mature Secondary Structure
MRHQYCRAFLVFLLPGFPVSLHAADSPDAFVPPTRLTRIAFDRRSAAFGQLDFLLGEIGR
CCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMQERMEVVRLTPQRALDIGCGHGQGLAGLRARFPDAQIAGLDISGVMLAEAGQRDPQRR
HHHHHHHHHHCCHHHHHCCCCCCCCCCCHHHHCCCCCEEECCCCCCCCEECCCCCCCCCC
PGWVGRLLGKRPLFDLVQGDLATLPFAPGSFDLLWSNLALHWHPEPHRVFPEWHRVTRDD
CCHHHHHHCCCHHHHHHCCCHHCCCCCCCCHHHHHHCCEEEECCCCCCCCHHHHHHCCCC
GLVMFSLFGPDTLRELRTAFEEVDTATHTLRFVDMHDIGDMLVHGGWSTPVMDMETLTVT
CEEEEEECCCHHHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHEECCCCCCCEEEEEEEEE
YESPEMLLREVQAFGGLRAHPALRRAGLHGRRWHQAVCAALERLRNADGVIPLTFEIVYG
ECCHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEC
HAWKLPPRGAQQVDELGRAVVPLDKIGRARPRR
CEECCCCCCHHHHHHHCCEECCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3058702; 9278503 [H]