Click here to switch to the map view.

The map label for this gene is comM [H]

Identifier: 73539994

GI number: 73539994

Start: 320564

End: 322105

Strand: Reverse

Name: comM [H]

Synonym: Reut_A0288

Alternate gene names: 73539994

Gene position: 322105-320564 (Counterclockwise)

Preceding gene: 73539995

Following gene: 73539991

Centisome position: 8.46

GC content: 69.97

Gene sequence:

>1542_bases
ATGAGCCTCGCCGTCCTGCATAGCCGCGCGCTCACCGGCATCGAAGCGCCGCCCGTGCGCGTCGAAACCCATCTGGCCAA
CGGCCTCCCCGTCTTCACCATCGTCGGCCTGGCCGACACCGGCGTACGCGAAAGCCGCGAACGCGTACGTGCCGCCATCA
TCAATAGCGGCTTTGAATTCCCGAACCGCCGCATCACCGTCAATCTGGCGCCAGCGGACTTGCCGAAGGAGTCCGGGCGA
TTCGACCTGGCCATTGCGCTGGGCATCCTGGCGGCGAGCGGCCAGATTCCCTCCGCCGAGTTCGATCAGTACGAGTTCGC
CGCCGAACTGTCGCTGTCCGGCGACCTGCGCCCGGTGCGCGGCGCGCTGGCGATGGCCATGCGCCTGGCGCGCGAAAACG
CCGCGCGGCAGGTCTCCGGCGGCAACCCTCGCGCGTTTCTGGTGGCGGCAGGCAACGGGGCCGAAGCGGCATTGATCGAA
GACCTGACCGTCCACAGCGGCACCACGCTGCGCGAGGTCTGCGCCCATTTCACGCCACCGCACGACCGTCGGCTGGCCCG
CGCCGTACCGGCCGCGCTCTCGCGGGTGCCGGAGCCCGGGCCGGACCTGCGCGACGTACGTGGCCAGGCGCAGGCGCGGC
GTGCCATGGAAGTGGCCGCCGCCGGCCAGCATTCGGCATTGCTCGTTGGACCTCCCGGAACCGGCAAGTCGATGCTGGCT
CAGCGGCTGCCGGGGCTGCTGCCGCCCATGTCACTCGATGAAGCGCTCGAGTCAGCCGCCGTGCTCAGCCTGACGCCGGG
CGGCTTCAAGCCGTCGCGATGGGGCGTGCGGCCGTGCCGCGCGCCTCACCACACCGCTTCGGGGCCGGCCATGGTGGGCG
GCGGCGGGAATCCTCGCCCCGGCGAGATCTCGCTGGCCCACCACGGCGTGCTATTCCTCGACGAATTGCCGGAGTTCGAC
CGAAAGGTGCTGGAGGTGCTACGCGAGCCGCTGGAATCTGGCCGTATTACCATCGCACGCGCCGCAGGCCACGCCGACTT
CCCGGCGTGCTTCCAGTTCGTGGCGGCCATGAATCCCTGCCCTTGCGGCTATCTCGGGCACCCCGAACGCGCGTGCCGCT
GCACGCCGGACCAGATCCGGCGCTACCAGTCGAAGATATCGGGGCCGCTACTGGACCGGATCGACCTGCAGATCGAAGTA
CCGGCCCAGGACCAGGGCGAGATGCTGGACGGGCCCGCGGGTGAATCCAGCGAAGTCGTGCGCGCACGGGTGCTGGCGGC
GCGCGAACGCCAGCTTGCGCGGCAGGGCAAACCCAACAGCGACCTGTCCGGCCGTGAGATCGACAAGCACTGCCCGCTGG
AACCGACCGCCCAGGCCTTGCTGCGCGGGGCCATGGCGCGGCTGGCATGGTCGGCGCGCTCTTACTTCCGGGTGCTCAAG
GTGGCCCGCACGATTGCGGATCTGGAAGGTGCTGAAGTCCTGACCACCGCGCACGTGGGCGAAGCGATCCAATACCGGCG
CGCCTTGCGCACGCCGGGATGA

Upstream 100 bases:

>100_bases
GGCGCATGACGCCACGGTCCAGCGACCCGATCCTTGCCGAAAGGCCGCCGTTTCACGGCGGCCTTTTTCGTTAACGCTTC
CATCACAACTTCTTCCCGAT

Downstream 100 bases:

>100_bases
GGGAGATCCAATGCGCTCAGCGGCGCGGCGGCACGCCGACGGGCGGATCGACCGGAGGCGGAACCGGATCCTCTTCGGGC
GGCAAAGGCAGATCAGGCGG

Product: Mg chelatase-related protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 513; Mature: 512

Protein sequence:

>513_residues
MSLAVLHSRALTGIEAPPVRVETHLANGLPVFTIVGLADTGVRESRERVRAAIINSGFEFPNRRITVNLAPADLPKESGR
FDLAIALGILAASGQIPSAEFDQYEFAAELSLSGDLRPVRGALAMAMRLARENAARQVSGGNPRAFLVAAGNGAEAALIE
DLTVHSGTTLREVCAHFTPPHDRRLARAVPAALSRVPEPGPDLRDVRGQAQARRAMEVAAAGQHSALLVGPPGTGKSMLA
QRLPGLLPPMSLDEALESAAVLSLTPGGFKPSRWGVRPCRAPHHTASGPAMVGGGGNPRPGEISLAHHGVLFLDELPEFD
RKVLEVLREPLESGRITIARAAGHADFPACFQFVAAMNPCPCGYLGHPERACRCTPDQIRRYQSKISGPLLDRIDLQIEV
PAQDQGEMLDGPAGESSEVVRARVLAARERQLARQGKPNSDLSGREIDKHCPLEPTAQALLRGAMARLAWSARSYFRVLK
VARTIADLEGAEVLTTAHVGEAIQYRRALRTPG

Sequences:

>Translated_513_residues
MSLAVLHSRALTGIEAPPVRVETHLANGLPVFTIVGLADTGVRESRERVRAAIINSGFEFPNRRITVNLAPADLPKESGR
FDLAIALGILAASGQIPSAEFDQYEFAAELSLSGDLRPVRGALAMAMRLARENAARQVSGGNPRAFLVAAGNGAEAALIE
DLTVHSGTTLREVCAHFTPPHDRRLARAVPAALSRVPEPGPDLRDVRGQAQARRAMEVAAAGQHSALLVGPPGTGKSMLA
QRLPGLLPPMSLDEALESAAVLSLTPGGFKPSRWGVRPCRAPHHTASGPAMVGGGGNPRPGEISLAHHGVLFLDELPEFD
RKVLEVLREPLESGRITIARAAGHADFPACFQFVAAMNPCPCGYLGHPERACRCTPDQIRRYQSKISGPLLDRIDLQIEV
PAQDQGEMLDGPAGESSEVVRARVLAARERQLARQGKPNSDLSGREIDKHCPLEPTAQALLRGAMARLAWSARSYFRVLK
VARTIADLEGAEVLTTAHVGEAIQYRRALRTPG
>Mature_512_residues
SLAVLHSRALTGIEAPPVRVETHLANGLPVFTIVGLADTGVRESRERVRAAIINSGFEFPNRRITVNLAPADLPKESGRF
DLAIALGILAASGQIPSAEFDQYEFAAELSLSGDLRPVRGALAMAMRLARENAARQVSGGNPRAFLVAAGNGAEAALIED
LTVHSGTTLREVCAHFTPPHDRRLARAVPAALSRVPEPGPDLRDVRGQAQARRAMEVAAAGQHSALLVGPPGTGKSMLAQ
RLPGLLPPMSLDEALESAAVLSLTPGGFKPSRWGVRPCRAPHHTASGPAMVGGGGNPRPGEISLAHHGVLFLDELPEFDR
KVLEVLREPLESGRITIARAAGHADFPACFQFVAAMNPCPCGYLGHPERACRCTPDQIRRYQSKISGPLLDRIDLQIEVP
AQDQGEMLDGPAGESSEVVRARVLAARERQLARQGKPNSDLSGREIDKHCPLEPTAQALLRGAMARLAWSARSYFRVLKV
ARTIADLEGAEVLTTAHVGEAIQYRRALRTPG

Specific function: Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step [H]

COG id: COG0606

COG function: function code O; Predicted ATPase with chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693202, Length=508, Percent_Identity=49.4094488188976, Blast_Score=464, Evalue=1e-132,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR004482
- InterPro:   IPR000523
- InterPro:   IPR020568 [H]

Pfam domain/function: PF01078 Mg_chelatase [H]

EC number: NA

Molecular weight: Translated: 54815; Mature: 54684

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLAVLHSRALTGIEAPPVRVETHLANGLPVFTIVGLADTGVRESRERVRAAIINSGFEF
CCCHHHHHHHHCCCCCCCEEEEHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCC
PNRRITVNLAPADLPKESGRFDLAIALGILAASGQIPSAEFDQYEFAAELSLSGDLRPVR
CCCEEEEEECCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCCCHHHHEEEECCCCCHHHH
GALAMAMRLARENAARQVSGGNPRAFLVAAGNGAEAALIEDLTVHSGTTLREVCAHFTPP
HHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHCCCCCHHHHHHHHCCCC
HDRRLARAVPAALSRVPEPGPDLRDVRGQAQARRAMEVAAAGQHSALLVGPPGTGKSMLA
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHH
QRLPGLLPPMSLDEALESAAVLSLTPGGFKPSRWGVRPCRAPHHTASGPAMVGGGGNPRP
HHCCCCCCCCCHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCC
GEISLAHHGVLFLDELPEFDRKVLEVLREPLESGRITIARAAGHADFPACFQFVAAMNPC
CEEEEECCCEEEEHHCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCC
PCGYLGHPERACRCTPDQIRRYQSKISGPLLDRIDLQIEVPAQDQGEMLDGPAGESSEVV
CCCCCCCCCHHCCCCHHHHHHHHHHHCCCCHHHEEEEEECCCCCCCCCCCCCCCCCHHHH
RARVLAARERQLARQGKPNSDLSGREIDKHCPLEPTAQALLRGAMARLAWSARSYFRVLK
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VARTIADLEGAEVLTTAHVGEAIQYRRALRTPG
HHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLAVLHSRALTGIEAPPVRVETHLANGLPVFTIVGLADTGVRESRERVRAAIINSGFEF
CCHHHHHHHHCCCCCCCEEEEHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCC
PNRRITVNLAPADLPKESGRFDLAIALGILAASGQIPSAEFDQYEFAAELSLSGDLRPVR
CCCEEEEEECCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCCCHHHHEEEECCCCCHHHH
GALAMAMRLARENAARQVSGGNPRAFLVAAGNGAEAALIEDLTVHSGTTLREVCAHFTPP
HHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHCCCCCHHHHHHHHCCCC
HDRRLARAVPAALSRVPEPGPDLRDVRGQAQARRAMEVAAAGQHSALLVGPPGTGKSMLA
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHH
QRLPGLLPPMSLDEALESAAVLSLTPGGFKPSRWGVRPCRAPHHTASGPAMVGGGGNPRP
HHCCCCCCCCCHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCC
GEISLAHHGVLFLDELPEFDRKVLEVLREPLESGRITIARAAGHADFPACFQFVAAMNPC
CEEEEECCCEEEEHHCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCC
PCGYLGHPERACRCTPDQIRRYQSKISGPLLDRIDLQIEVPAQDQGEMLDGPAGESSEVV
CCCCCCCCCHHCCCCHHHHHHHHHHHCCCCHHHEEEEEECCCCCCCCCCCCCCCCCHHHH
RARVLAARERQLARQGKPNSDLSGREIDKHCPLEPTAQALLRGAMARLAWSARSYFRVLK
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VARTIADLEGAEVLTTAHVGEAIQYRRALRTPG
HHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9457884 [H]