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The map label for this gene is argB

Identifier: 73539886

GI number: 73539886

Start: 204228

End: 205157

Strand: Direct

Name: argB

Synonym: Reut_A0180

Alternate gene names: 73539886

Gene position: 204228-205157 (Clockwise)

Preceding gene: 73539882

Following gene: 73539887

Centisome position: 5.37

GC content: 64.3

Gene sequence:

>930_bases
ATGTCCCCAGCCATGAACGCCGACAACCCTGGAGCTGCCGCGACTGCGGTGGCCGCTATCGCCCCCGCCCTCAAGGCCGA
GATCCTCGCCGAGGCGCTGCCCTATATCCGCAAGTTCCACGGCAAGACCATCGTGGTCAAGTACGGCGGCAATGCCATGA
CCGAGGAAAAGCTCAAGCACGGCTTCGCGCGCGACGTGATCCTGCTGAAGCTGGTCGGCATGAACCCGGTGGTGGTGCAC
GGCGGCGGCCCGCAGATCGATGAGGCGCTGAAGAAGGTCGGCAAGGTCGGCACCTTCGTGCAGGGCATGCGCGTGACTGA
CGAAGAGACCATGGAAGTGGTCGAGTGGGTGCTCGGCGGTGAGGTCCAGCAGGACATCGTGATGCTGATCAACCAGTACG
GCGGCCAGGCCGTGGGCCTGACCGGCAAGGACGGCGGCCTGATCCGCGCCAAGCGCCTGCAGATGCCCGATCGCGAGAAT
CCGGGTGCGTTCATCGACATCGGCTACGTCGGCGACATCGAAGCCATCAACCCGGCCGTGGTCAAGGCACTGCAGGACGA
CGCCTTCATCCCGGTGATCTCGCCGATCGGCTTCTCCGACGACGGCCAGGCCTACAACATCAACGCCGACGTGGTTGCCG
GCAAGATGGCCGAGATCCTCAAGGCCGAGAAGCTGGTCATGATGACCAACATCCCCGGCGTGATGGACAAGAAGGGCAAC
CTGCTGACCGACCTGTCCGCGCGCGAGATCGAGGAGTTGTTCGCCGACGGCACCATCTCGGGCGGCATGCTGCCGAAGAT
CTCGTCGGCGCTCGACGCCGCCAAGAGCGGCGTGCATTCGGTTCACATCATCGATGGCCGCATCGAGCACTCGCTGCTGC
TGGAAATCCTGACCGAACAGGCGTTCGGCACGATGATCCGCTCGCACTGA

Upstream 100 bases:

>100_bases
CGGCGCCTGCCGTGGCCCTATGGTGCACTTTCGGGCGATCCCCGTGAGTTTTCCGTCAGGTTTGCGGCAGATTTGCCATC
ATACCTGTTGATTCTCACGG

Downstream 100 bases:

>100_bases
GCGGCGCCACGGGGCGGCACCCGACTGGCGCGCTGCCCGCTGTTTTCTCCCCCATTGCCTCAGCACCGATCCGGCGTGTC
TTCCAGTCATTCCCCTTCGC

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MSPAMNADNPGAAATAVAAIAPALKAEILAEALPYIRKFHGKTIVVKYGGNAMTEEKLKHGFARDVILLKLVGMNPVVVH
GGGPQIDEALKKVGKVGTFVQGMRVTDEETMEVVEWVLGGEVQQDIVMLINQYGGQAVGLTGKDGGLIRAKRLQMPDREN
PGAFIDIGYVGDIEAINPAVVKALQDDAFIPVISPIGFSDDGQAYNINADVVAGKMAEILKAEKLVMMTNIPGVMDKKGN
LLTDLSAREIEELFADGTISGGMLPKISSALDAAKSGVHSVHIIDGRIEHSLLLEILTEQAFGTMIRSH

Sequences:

>Translated_309_residues
MSPAMNADNPGAAATAVAAIAPALKAEILAEALPYIRKFHGKTIVVKYGGNAMTEEKLKHGFARDVILLKLVGMNPVVVH
GGGPQIDEALKKVGKVGTFVQGMRVTDEETMEVVEWVLGGEVQQDIVMLINQYGGQAVGLTGKDGGLIRAKRLQMPDREN
PGAFIDIGYVGDIEAINPAVVKALQDDAFIPVISPIGFSDDGQAYNINADVVAGKMAEILKAEKLVMMTNIPGVMDKKGN
LLTDLSAREIEELFADGTISGGMLPKISSALDAAKSGVHSVHIIDGRIEHSLLLEILTEQAFGTMIRSH
>Mature_308_residues
SPAMNADNPGAAATAVAAIAPALKAEILAEALPYIRKFHGKTIVVKYGGNAMTEEKLKHGFARDVILLKLVGMNPVVVHG
GGPQIDEALKKVGKVGTFVQGMRVTDEETMEVVEWVLGGEVQQDIVMLINQYGGQAVGLTGKDGGLIRAKRLQMPDRENP
GAFIDIGYVGDIEAINPAVVKALQDDAFIPVISPIGFSDDGQAYNINADVVAGKMAEILKAEKLVMMTNIPGVMDKKGNL
LTDLSAREIEELFADGTISGGMLPKISSALDAAKSGVHSVHIIDGRIEHSLLLEILTEQAFGTMIRSH

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI1789181, Length=283, Percent_Identity=28.6219081272085, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI145693208, Length=245, Percent_Identity=30.2040816326531, Blast_Score=104, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6320913, Length=268, Percent_Identity=28.3582089552239, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGB_CUPPJ (Q476X1)

Other databases:

- EMBL:   CP000090
- RefSeq:   YP_294406.1
- HSSP:   Q9HTN2
- ProteinModelPortal:   Q476X1
- SMR:   Q476X1
- GeneID:   3610436
- GenomeReviews:   CP000090_GR
- KEGG:   reu:Reut_A0180
- NMPDR:   fig|264198.3.peg.692
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- ProtClustDB:   PRK00942
- BioCyc:   REUT264198:REUT_A0180-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 32833; Mature: 32701

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: BINDING 104-104 BINDING 206-206

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPAMNADNPGAAATAVAAIAPALKAEILAEALPYIRKFHGKTIVVKYGGNAMTEEKLKH
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHC
GFARDVILLKLVGMNPVVVHGGGPQIDEALKKVGKVGTFVQGMRVTDEETMEVVEWVLGG
CHHHHHHEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC
EVQQDIVMLINQYGGQAVGLTGKDGGLIRAKRLQMPDRENPGAFIDIGYVGDIEAINPAV
CHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCCCCCCCCCCEEEECCCCCCCCCCHHH
VKALQDDAFIPVISPIGFSDDGQAYNINADVVAGKMAEILKAEKLVMMTNIPGVMDKKGN
HHHHCCCCCEEEECCCCCCCCCCEEECCHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCC
LLTDLSAREIEELFADGTISGGMLPKISSALDAAKSGVHSVHIIDGRIEHSLLLEILTEQ
EEECCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHH
AFGTMIRSH
HHHHHHHCC
>Mature Secondary Structure 
SPAMNADNPGAAATAVAAIAPALKAEILAEALPYIRKFHGKTIVVKYGGNAMTEEKLKH
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHC
GFARDVILLKLVGMNPVVVHGGGPQIDEALKKVGKVGTFVQGMRVTDEETMEVVEWVLGG
CHHHHHHEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC
EVQQDIVMLINQYGGQAVGLTGKDGGLIRAKRLQMPDRENPGAFIDIGYVGDIEAINPAV
CHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCCCCCCCCCCEEEECCCCCCCCCCHHH
VKALQDDAFIPVISPIGFSDDGQAYNINADVVAGKMAEILKAEKLVMMTNIPGVMDKKGN
HHHHCCCCCEEEECCCCCCCCCCEEECCHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCC
LLTDLSAREIEELFADGTISGGMLPKISSALDAAKSGVHSVHIIDGRIEHSLLLEILTEQ
EEECCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHH
AFGTMIRSH
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA