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The map label for this gene is yjiA [H]

Identifier: 73539869

GI number: 73539869

Start: 190596

End: 191669

Strand: Reverse

Name: yjiA [H]

Synonym: Reut_A0163

Alternate gene names: 73539869

Gene position: 191669-190596 (Counterclockwise)

Preceding gene: 73539870

Following gene: 73539868

Centisome position: 5.04

GC content: 62.38

Gene sequence:

>1074_bases
ATGTCCAAACTGATCCCGGTCACGATCCTGACCGGCTTCCTCGGCAGCGGCAAGACCACGCTGCTCAAGCGCATCCTCAA
CGAGCAGCACGGCATGAAGATCGCCGTGATCGAGAACGAATTCGGCGAAGAGAACATCGACAACGAAATCCTGGTACAGG
ACGGCCGCGAGCAGATCGTGCAAATGAGCAACGGCTGCATCTGCTGCACGATCCGCGGCGACCTGGTGCAGGCGCTGTCG
ACGCTGATGACGCGGCGCGACGCGGGTGAGATCGAGTTCGACCGCGTGGTCATCGAAACCACCGGCGTGGCCAATCCGGG
ACCGGTCGCGCAGACCTTCTTCATGGACGACGAGATCGCGTCGCGCTACCTGCTGGACGCGGTGATCACGCTGGTCGATG
CCAAGCACGCCCACCTGCAGCTCGACAAGCAGGAAGAGGCGCAGCGCCAGGTCGGCTTTGCCGACGCGATCTTCATCACC
AAGTCGGACCTGGTCAGCGAGGCCGAGGTGGCCGAACTGCGCCACCGCCTGCTGCACATGAACCCGCGCGCCCCGATCCG
CCAGGCCAACTTCGGCGAGACGCCGATCGACACCATCTTCGACCTGCGCGGCTTCAACCTGAATGCCAAGCTGGAGATCG
ATCCGGAGTTCCTGAGCGCCGATGACCACGATCACGGTCATGGCCACGACCATGAGCACGAGCACGAGCACGGAGAGCAT
TGCGGCACGGAGTGCGGCCATGACCACAGCCACGACCACCATCATCACCACCACCACACCGACCGCATCGCGTCGTTCGT
CTTCCGCAGCGACAAGCCGTTCCACTACGGCAAGCTTGAGGAATTCCTGTCGGGCATCCTGGCCGTCTATGGGGAAAAAC
TCTTGCGCTACAAGGGCGTACTATATATGGAAGGTGTGGACCGGAAAGTCGTGTTCCAGGGAGTCCACCAACTGATGGGC
AGCGACGTCGGTGCCAAGTGGGAAGAGGAGACGCCTGGCACCAAGATGGTGTTCATCGGCGTGGACCTGCCCCGCGATGC
CATTCTGAAGGGGCTGGGCAACTGCCTGGCCTGA

Upstream 100 bases:

>100_bases
GTGTGCGCCGACTGCGGCGCGCGGGTGGCTCGGCACCCCGACAGCGCAACCTGACGCCCTGCCCGGCGCAAGGCCCCCAA
TTCCCCCGGAGAATCCACCC

Downstream 100 bases:

>100_bases
GTGCGGCAGCCGCCCCACGGCGGCTATCTCGCTCCGCGTCGGCTCCGGCATGTCCCCCGTTCGGGGTACCGGGGAAACAC
CGAAGGCATGGCTAGGCCTT

Product: cobalamin synthesis protein/P47K:cobalamin synthesis CobW, C-terminal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MSKLIPVTILTGFLGSGKTTLLKRILNEQHGMKIAVIENEFGEENIDNEILVQDGREQIVQMSNGCICCTIRGDLVQALS
TLMTRRDAGEIEFDRVVIETTGVANPGPVAQTFFMDDEIASRYLLDAVITLVDAKHAHLQLDKQEEAQRQVGFADAIFIT
KSDLVSEAEVAELRHRLLHMNPRAPIRQANFGETPIDTIFDLRGFNLNAKLEIDPEFLSADDHDHGHGHDHEHEHEHGEH
CGTECGHDHSHDHHHHHHHTDRIASFVFRSDKPFHYGKLEEFLSGILAVYGEKLLRYKGVLYMEGVDRKVVFQGVHQLMG
SDVGAKWEEETPGTKMVFIGVDLPRDAILKGLGNCLA

Sequences:

>Translated_357_residues
MSKLIPVTILTGFLGSGKTTLLKRILNEQHGMKIAVIENEFGEENIDNEILVQDGREQIVQMSNGCICCTIRGDLVQALS
TLMTRRDAGEIEFDRVVIETTGVANPGPVAQTFFMDDEIASRYLLDAVITLVDAKHAHLQLDKQEEAQRQVGFADAIFIT
KSDLVSEAEVAELRHRLLHMNPRAPIRQANFGETPIDTIFDLRGFNLNAKLEIDPEFLSADDHDHGHGHDHEHEHEHGEH
CGTECGHDHSHDHHHHHHHTDRIASFVFRSDKPFHYGKLEEFLSGILAVYGEKLLRYKGVLYMEGVDRKVVFQGVHQLMG
SDVGAKWEEETPGTKMVFIGVDLPRDAILKGLGNCLA
>Mature_356_residues
SKLIPVTILTGFLGSGKTTLLKRILNEQHGMKIAVIENEFGEENIDNEILVQDGREQIVQMSNGCICCTIRGDLVQALST
LMTRRDAGEIEFDRVVIETTGVANPGPVAQTFFMDDEIASRYLLDAVITLVDAKHAHLQLDKQEEAQRQVGFADAIFITK
SDLVSEAEVAELRHRLLHMNPRAPIRQANFGETPIDTIFDLRGFNLNAKLEIDPEFLSADDHDHGHGHDHEHEHEHGEHC
GTECGHDHSHDHHHHHHHTDRIASFVFRSDKPFHYGKLEEFLSGILAVYGEKLLRYKGVLYMEGVDRKVVFQGVHQLMGS
DVGAKWEEETPGTKMVFIGVDLPRDAILKGLGNCLA

Specific function: Binds GTP. May function as GTP-dependent regulator [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=368, Percent_Identity=31.7934782608696, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI126722884, Length=368, Percent_Identity=31.7934782608696, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI146231952, Length=368, Percent_Identity=31.7934782608696, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI148727351, Length=368, Percent_Identity=31.5217391304348, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI223941779, Length=371, Percent_Identity=32.3450134770889, Blast_Score=155, Evalue=4e-38,
Organism=Homo sapiens, GI223941776, Length=358, Percent_Identity=31.0055865921788, Blast_Score=151, Evalue=8e-37,
Organism=Homo sapiens, GI119120938, Length=218, Percent_Identity=35.7798165137615, Blast_Score=125, Evalue=4e-29,
Organism=Escherichia coli, GI87082430, Length=345, Percent_Identity=41.1594202898551, Blast_Score=244, Evalue=6e-66,
Organism=Escherichia coli, GI1788499, Length=166, Percent_Identity=33.1325301204819, Blast_Score=67, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324356, Length=227, Percent_Identity=33.0396475770925, Blast_Score=129, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 40050; Mature: 39919

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLIPVTILTGFLGSGKTTLLKRILNEQHGMKIAVIENEFGEENIDNEILVQDGREQIV
CCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEECCCHHHHH
QMSNGCICCTIRGDLVQALSTLMTRRDAGEIEFDRVVIETTGVANPGPVAQTFFMDDEIA
HHCCCEEEEEECHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCHHEEECCHHHH
SRYLLDAVITLVDAKHAHLQLDKQEEAQRQVGFADAIFITKSDLVSEAEVAELRHRLLHM
HHHHHHHHHHHHCCCHHHEECCCHHHHHHHCCCHHEEEEEHHHHHHHHHHHHHHHHHHCC
NPRAPIRQANFGETPIDTIFDLRGFNLNAKLEIDPEFLSADDHDHGHGHDHEHEHEHGEH
CCCCCCCCCCCCCCCHHHHHHCCCCCCCEEEEECHHHHCCCCCCCCCCCCCCCCHHHHHH
CGTECGHDHSHDHHHHHHHTDRIASFVFRSDKPFHYGKLEEFLSGILAVYGEKLLRYKGV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCE
LYMEGVDRKVVFQGVHQLMGSDVGAKWEEETPGTKMVFIGVDLPRDAILKGLGNCLA
EEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SKLIPVTILTGFLGSGKTTLLKRILNEQHGMKIAVIENEFGEENIDNEILVQDGREQIV
CCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEECCCHHHHH
QMSNGCICCTIRGDLVQALSTLMTRRDAGEIEFDRVVIETTGVANPGPVAQTFFMDDEIA
HHCCCEEEEEECHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCHHEEECCHHHH
SRYLLDAVITLVDAKHAHLQLDKQEEAQRQVGFADAIFITKSDLVSEAEVAELRHRLLHM
HHHHHHHHHHHHCCCHHHEECCCHHHHHHHCCCHHEEEEEHHHHHHHHHHHHHHHHHHCC
NPRAPIRQANFGETPIDTIFDLRGFNLNAKLEIDPEFLSADDHDHGHGHDHEHEHEHGEH
CCCCCCCCCCCCCCCHHHHHHCCCCCCCEEEEECHHHHCCCCCCCCCCCCCCCCHHHHHH
CGTECGHDHSHDHHHHHHHTDRIASFVFRSDKPFHYGKLEEFLSGILAVYGEKLLRYKGV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCE
LYMEGVDRKVVFQGVHQLMGSDVGAKWEEETPGTKMVFIGVDLPRDAILKGLGNCLA
EEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 1650347 [H]