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The map label for this gene is cirA [C]

Identifier: 73539865

GI number: 73539865

Start: 185474

End: 187657

Strand: Reverse

Name: cirA [C]

Synonym: Reut_A0159

Alternate gene names: 73539865

Gene position: 187657-185474 (Counterclockwise)

Preceding gene: 73539866

Following gene: 73539838

Centisome position: 4.93

GC content: 66.44

Gene sequence:

>2184_bases
ATGCCGGCACCGCGCGGCCGTTCGCCCGATTGCCATCGCATCGAATCGCGAGCCATGTCTTCTACCCTGCAACACCTCAT
GCTGCGGCGCACGCCGCTGGCAGCCTTTGCTGCCCTGATCGTCTCGAACGGCGCATTCGCCCAGTCCGCCAGCGAACCTG
CGGCGGCCCCTGCGCCCGCCGCTGCCACCCTCAAGGAAGTGGTGGTCACCGCGAACCCGCTGGGCAGCGACCTCAACGAC
ATGGTCGCGCCGGTCTCCTCACTGAGCGGCGACGCGCTGTCGCTGCGCCAGAACAGCACGCTCGGCGAAACGCTGGACAA
GTTGCCGGGCGTGTCGTCGAGCTACTTCGGCCCCAACGCCAGCCGGCCCGTGATCCGCGGACTCGATGCCGACCGCATCA
AGGTGCTGCAGAACGGCGGCTCCTCGGTCGATGCCTCGACGCTGTCCTACGACCACGCCGTACCGATCGATCCGCTCGTG
GCCGAGCGCATTGAAGTCGTGCGCGGCCCCGCCGCGCTGATGTACGGCGGCAACGCCATCGGCGGCGTCGTCAACGTGAT
CGATAACCGCATCCCGAAGGAGCCCATTGAAGGCATCGGCGGCGCTGTCGATGCCAGCGCCACGGCCGGCGGCGACGTGG
CGCGCAACGCCAGCGCGCTGGTCGAGGCCGGCAACGGCCAGTTCGCAATCCACGCCGACGCCTTCGCGCGCAAGACCAGC
GACCTGCATATTCCCGGATTCGCGCGTAGCGACCGCCTGCGCGCAAGCCAGCCGCTGCCCGAGGGCGAAACCGAGGCCAG
CGGCCGCCTGCCCAACACCAGCGCGCAGCAGGACGGCGGCGCGCTGGGCGGCTCGTACACGTGGGCCGACGGCTTCATCG
GCGCGAACTACAGCGCCTACCGCAACGAATACGGCACGCCTGCCGAAGACGACGTCCGCCTGAAAATGCGCCAGGACCGC
TTCGCGCTCGAAGGCGAAGCGCGCAACCTGCAGGCCAACACGTCCGGCATCATCGAATCGGTCAAGGGCAAGTTCAGCTA
CACCGACTATGAGCACAAGGAAATCGAAGACGGCCAGGTCGGCACCATCTTCAAGAACCAGGGCTGGGACGCACGCTTCG
AGGCCAAGCACGCGAAGATCGGCAACATGAGCGGGGTCGTCGGCACGCAGTTCGGCCACACGCAGTTCTCCGCGCTCGGC
GAAGAAGCCTTCGTGCCGAGCACCAATACCGACAACGCCGCGCTGTTCGTCTTCGAAGAACTGCCGCTCGATAGCGCCGG
CGACTTCAAGCTCAACTTCGGCGGCCGGCTGGATCACAGCAATATCAAGGCCAGTGCGAACGGCAACGACCGCTTCAGCG
ATGCCGACCGCAGCTTCAACGCCACCAGTGCATCGGCGGGCCTGCTCTACAAGCTGAATTCGCTGTGGTCGCTGACCAGC
AATGTGTCGTACACCGAGCGCGCACCGACCTTCTACGAGCTGTACGCCAACGGCCCGCACGTCGCCACCGGCGCCTGGGA
GCTCGGCGATCCCAACGCCAACAAGGAACGCGCCACCTCGGTGGATCTCGGCCTGCGCTACAAGTACGGCCCGCACAGTG
CCGGCGTGTCGGGCTACTACAGCCGCTTCGCCAACTACCTCGCACTGACGTCGACGGGCCGCTCGCGCGACGAGGCTGGC
GACGTGGTCGCGTCCGGCAGTCCCGGCGCGCTGCCCGAGTTCGAGTACCTCGGCGTACCGGCCACGCTGTATGGTTTCGA
AGCCGAAGGCAAGGCGCGGCTGTTCCAGAAGATGCTGACGTCGAGCGATACGCTGGACTTCGAGGCACGGGCGGATTATG
TGCGCGGAGAGAACCGGGATACCGGGGAGCCGCTGCCGAGGCTGGCGCCTTTGCGTCTGGGCGGCGCGCTGGTCTATGGT
GCGGGGCCTTGGGGGGCGCGTGTGGATGTTACCTATGCGGCCAAGCAGACGCGCGTGCCGGTCAACGATACGCCGACCGA
TGCGTACACGCTTCTCAGCCTTGCGCTGACGTACAAGTTCAAGACTTCCGGGACACAGACGCTGATCTACCTGCGCGGCG
ATAACCTGACGAATCAGGAGGCGCGGAATGCGTCGTCGATTCTGCGGGATATTGCGCCGTTGCCGGGGAGGAGTGTGAAG
GTGGGGTTCAGGACGACGTTCTGA

Upstream 100 bases:

>100_bases
CCCGGGCCGCGGCCAAGCCGCAGGCCCGCAGTACGAAGCGCGCGTCCACGCCTGCCGGCTCTGCCCACGACCTCGCACCT
TCCCGTGCGGGCTCCGTACC

Downstream 100 bases:

>100_bases
GAGTTGGGGGCGGCTGTTATTGGGGCCGGTGTCGTTTTTGACCGGCGCCGCTGTTTCGCCGGCGTAGCCGGCGACTTACT
TCTTCCTAGTCGGTATTGGT

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 727; Mature: 726

Protein sequence:

>727_residues
MPAPRGRSPDCHRIESRAMSSTLQHLMLRRTPLAAFAALIVSNGAFAQSASEPAAAPAPAAATLKEVVVTANPLGSDLND
MVAPVSSLSGDALSLRQNSTLGETLDKLPGVSSSYFGPNASRPVIRGLDADRIKVLQNGGSSVDASTLSYDHAVPIDPLV
AERIEVVRGPAALMYGGNAIGGVVNVIDNRIPKEPIEGIGGAVDASATAGGDVARNASALVEAGNGQFAIHADAFARKTS
DLHIPGFARSDRLRASQPLPEGETEASGRLPNTSAQQDGGALGGSYTWADGFIGANYSAYRNEYGTPAEDDVRLKMRQDR
FALEGEARNLQANTSGIIESVKGKFSYTDYEHKEIEDGQVGTIFKNQGWDARFEAKHAKIGNMSGVVGTQFGHTQFSALG
EEAFVPSTNTDNAALFVFEELPLDSAGDFKLNFGGRLDHSNIKASANGNDRFSDADRSFNATSASAGLLYKLNSLWSLTS
NVSYTERAPTFYELYANGPHVATGAWELGDPNANKERATSVDLGLRYKYGPHSAGVSGYYSRFANYLALTSTGRSRDEAG
DVVASGSPGALPEFEYLGVPATLYGFEAEGKARLFQKMLTSSDTLDFEARADYVRGENRDTGEPLPRLAPLRLGGALVYG
AGPWGARVDVTYAAKQTRVPVNDTPTDAYTLLSLALTYKFKTSGTQTLIYLRGDNLTNQEARNASSILRDIAPLPGRSVK
VGFRTTF

Sequences:

>Translated_727_residues
MPAPRGRSPDCHRIESRAMSSTLQHLMLRRTPLAAFAALIVSNGAFAQSASEPAAAPAPAAATLKEVVVTANPLGSDLND
MVAPVSSLSGDALSLRQNSTLGETLDKLPGVSSSYFGPNASRPVIRGLDADRIKVLQNGGSSVDASTLSYDHAVPIDPLV
AERIEVVRGPAALMYGGNAIGGVVNVIDNRIPKEPIEGIGGAVDASATAGGDVARNASALVEAGNGQFAIHADAFARKTS
DLHIPGFARSDRLRASQPLPEGETEASGRLPNTSAQQDGGALGGSYTWADGFIGANYSAYRNEYGTPAEDDVRLKMRQDR
FALEGEARNLQANTSGIIESVKGKFSYTDYEHKEIEDGQVGTIFKNQGWDARFEAKHAKIGNMSGVVGTQFGHTQFSALG
EEAFVPSTNTDNAALFVFEELPLDSAGDFKLNFGGRLDHSNIKASANGNDRFSDADRSFNATSASAGLLYKLNSLWSLTS
NVSYTERAPTFYELYANGPHVATGAWELGDPNANKERATSVDLGLRYKYGPHSAGVSGYYSRFANYLALTSTGRSRDEAG
DVVASGSPGALPEFEYLGVPATLYGFEAEGKARLFQKMLTSSDTLDFEARADYVRGENRDTGEPLPRLAPLRLGGALVYG
AGPWGARVDVTYAAKQTRVPVNDTPTDAYTLLSLALTYKFKTSGTQTLIYLRGDNLTNQEARNASSILRDIAPLPGRSVK
VGFRTTF
>Mature_726_residues
PAPRGRSPDCHRIESRAMSSTLQHLMLRRTPLAAFAALIVSNGAFAQSASEPAAAPAPAAATLKEVVVTANPLGSDLNDM
VAPVSSLSGDALSLRQNSTLGETLDKLPGVSSSYFGPNASRPVIRGLDADRIKVLQNGGSSVDASTLSYDHAVPIDPLVA
ERIEVVRGPAALMYGGNAIGGVVNVIDNRIPKEPIEGIGGAVDASATAGGDVARNASALVEAGNGQFAIHADAFARKTSD
LHIPGFARSDRLRASQPLPEGETEASGRLPNTSAQQDGGALGGSYTWADGFIGANYSAYRNEYGTPAEDDVRLKMRQDRF
ALEGEARNLQANTSGIIESVKGKFSYTDYEHKEIEDGQVGTIFKNQGWDARFEAKHAKIGNMSGVVGTQFGHTQFSALGE
EAFVPSTNTDNAALFVFEELPLDSAGDFKLNFGGRLDHSNIKASANGNDRFSDADRSFNATSASAGLLYKLNSLWSLTSN
VSYTERAPTFYELYANGPHVATGAWELGDPNANKERATSVDLGLRYKYGPHSAGVSGYYSRFANYLALTSTGRSRDEAGD
VVASGSPGALPEFEYLGVPATLYGFEAEGKARLFQKMLTSSDTLDFEARADYVRGENRDTGEPLPRLAPLRLGGALVYGA
GPWGARVDVTYAAKQTRVPVNDTPTDAYTLLSLALTYKFKTSGTQTLIYLRGDNLTNQEARNASSILRDIAPLPGRSVKV
GFRTTF

Specific function: Probable receptor, tonB-dependent [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=171, Percent_Identity=32.7485380116959, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1786344, Length=201, Percent_Identity=27.363184079602, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 77326; Mature: 77195

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAPRGRSPDCHRIESRAMSSTLQHLMLRRTPLAAFAALIVSNGAFAQSASEPAAAPAPA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHCCCCCCCCCCCCH
AATLKEVVVTANPLGSDLNDMVAPVSSLSGDALSLRQNSTLGETLDKLPGVSSSYFGPNA
HHHHHHHHEECCCCCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHCCCCCCCCCCCCC
SRPVIRGLDADRIKVLQNGGSSVDASTLSYDHAVPIDPLVAERIEVVRGPAALMYGGNAI
CCHHHCCCCHHHHHHHHCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCHH
GGVVNVIDNRIPKEPIEGIGGAVDASATAGGDVARNASALVEAGNGQFAIHADAFARKTS
HHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCHHCCCHHEEECCCCCEEEECHHHHCCCC
DLHIPGFARSDRLRASQPLPEGETEASGRLPNTSAQQDGGALGGSYTWADGFIGANYSAY
CEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCHHHH
RNEYGTPAEDDVRLKMRQDRFALEGEARNLQANTSGIIESVKGKFSYTDYEHKEIEDGQV
HHCCCCCCCCCEEEEEECCCEEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCE
GTIFKNQGWDARFEAKHAKIGNMSGVVGTQFGHTQFSALGEEAFVPSTNTDNAALFVFEE
EEEEECCCCCCEEEHHHCCCCCCCCCEECCCCCHHHHHCCCCCCCCCCCCCCEEEEEEEE
LPLDSAGDFKLNFGGRLDHSNIKASANGNDRFSDADRSFNATSASAGLLYKLNSLWSLTS
CCCCCCCCEEEECCCEECCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHC
NVSYTERAPTFYELYANGPHVATGAWELGDPNANKERATSVDLGLRYKYGPHSAGVSGYY
CCCCCCCCCEEEEEECCCCEEEECEEECCCCCCCCHHCCEEEEEEEEECCCCCCCHHHHH
SRFANYLALTSTGRSRDEAGDVVASGSPGALPEFEYLGVPATLYGFEAEGKARLFQKMLT
HHHHHHEEEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHC
SSDTLDFEARADYVRGENRDTGEPLPRLAPLRLGGALVYGAGPWGARVDVTYAAKQTRVP
CCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEECCEEEECCCCCCCEEEEEEEHHHCCCC
VNDTPTDAYTLLSLALTYKFKTSGTQTLIYLRGDNLTNQEARNASSILRDIAPLPGRSVK
CCCCCCHHHHHHHHHHEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEE
VGFRTTF
EEEEECC
>Mature Secondary Structure 
PAPRGRSPDCHRIESRAMSSTLQHLMLRRTPLAAFAALIVSNGAFAQSASEPAAAPAPA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHCCCCCCCCCCCCH
AATLKEVVVTANPLGSDLNDMVAPVSSLSGDALSLRQNSTLGETLDKLPGVSSSYFGPNA
HHHHHHHHEECCCCCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHCCCCCCCCCCCCC
SRPVIRGLDADRIKVLQNGGSSVDASTLSYDHAVPIDPLVAERIEVVRGPAALMYGGNAI
CCHHHCCCCHHHHHHHHCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCHH
GGVVNVIDNRIPKEPIEGIGGAVDASATAGGDVARNASALVEAGNGQFAIHADAFARKTS
HHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCHHCCCHHEEECCCCCEEEECHHHHCCCC
DLHIPGFARSDRLRASQPLPEGETEASGRLPNTSAQQDGGALGGSYTWADGFIGANYSAY
CEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCHHHH
RNEYGTPAEDDVRLKMRQDRFALEGEARNLQANTSGIIESVKGKFSYTDYEHKEIEDGQV
HHCCCCCCCCCEEEEEECCCEEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCE
GTIFKNQGWDARFEAKHAKIGNMSGVVGTQFGHTQFSALGEEAFVPSTNTDNAALFVFEE
EEEEECCCCCCEEEHHHCCCCCCCCCEECCCCCHHHHHCCCCCCCCCCCCCCEEEEEEEE
LPLDSAGDFKLNFGGRLDHSNIKASANGNDRFSDADRSFNATSASAGLLYKLNSLWSLTS
CCCCCCCCEEEECCCEECCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHC
NVSYTERAPTFYELYANGPHVATGAWELGDPNANKERATSVDLGLRYKYGPHSAGVSGYY
CCCCCCCCCEEEEEECCCCEEEECEEECCCCCCCCHHCCEEEEEEEEECCCCCCCHHHHH
SRFANYLALTSTGRSRDEAGDVVASGSPGALPEFEYLGVPATLYGFEAEGKARLFQKMLT
HHHHHHEEEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHC
SSDTLDFEARADYVRGENRDTGEPLPRLAPLRLGGALVYGAGPWGARVDVTYAAKQTRVP
CCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEECCEEEECCCCCCCEEEEEEEHHHCCCC
VNDTPTDAYTLLSLALTYKFKTSGTQTLIYLRGDNLTNQEARNASSILRDIAPLPGRSVK
CCCCCCHHHHHHHHHHEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEE
VGFRTTF
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]