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The map label for this gene is argS [H]

Identifier: 73539833

GI number: 73539833

Start: 153181

End: 154968

Strand: Direct

Name: argS [H]

Synonym: Reut_A0127

Alternate gene names: 73539833

Gene position: 153181-154968 (Clockwise)

Preceding gene: 73539831

Following gene: 73539834

Centisome position: 4.02

GC content: 68.29

Gene sequence:

>1788_bases
ATGCTGCCTGTTCAGACCTCCAATCTTGCCGCTGCGTTCACTGATGCCGTGCGCGCGCTCGCGCCGGCCGATGCGGCCCT
GCCCGCCGTGACATTCGAGCGGCCGAAGGCCGCCGCCCACGGCGACCTGGCATGCAACATCGCCATGCAGGTGGCGCGCG
CGCTCAAGAGCAATCCGCGCGAACTGGCCCAGCGCATCGTGGCGATGGTGCAGGCCGATCCGCGCGCGGCCGAACTGGTC
GCGGGCATGGAGATCGCCGGCCCGGGCTTCATCAACCTGCGCCTGACGCCGGCCGCCAAGGCGGACGTGTTGCGCGCGGT
GCTGAGCGAGGGCGACGGCTACGGCGCCCAGGAGCGCGGCATGCACGGCAACGTGCTGGTCGAATTCGTCTCGGCCAACC
CGACCGGCCCGCTGCACGTCGGCCATGGCCGTCAGGCGGCGCTCGGCGACGCGCTGGCCAATCTGCTGTCGTGGCAGGGC
TATGACGTGCACCGCGAGTTCTACTACAACGACGCCGGCGTGCAGATCCAGAACCTGGCCGTGTCGGTGCAGGCGCGCAC
GCGGGGCTTCAAGCCCGGCGATGCCAACTGGCCGGAAGCCGCCTACAACGGCGACTACATCGGCGACATCGCCGCCGACT
TCCTGGCCGGCAAGACCGTGAGCGCGTCCGATGGCGAGCCGGTGACCGCGTCGGGCAACCCAGAGGATCTCGACTCGATC
CGCAAATTCGCGGTGACCTACCTGCGCAACGAGCAGGACATCGACCTGCAGGCCTTCGGCGTCAAGTTCGACCACTACTA
CCTGGAATCATCGCTGTACACCGACGGCCGCGTCGAAGCCGCGGTGCAGGGTCTGGTCGGCAAGGGCAAGACCTACGAGA
GCGAAGGCGCGCTGTGGCTGCGCACCACCGACGACGGCGACGACAAGGACCGGGTCATGAAGAAGACCGACGGTACCTAC
ACGTACTTCGTGCCGGACGTGGCCTACCACACCACCAAGTGGGAGCGCGGCTTCACCAAGGTCATTAACGTACAGGGCAG
CGACCACCACGGCACCATCGCGCGCGTGCGCGCCGGGCTGCAGGGGCTCGACATCGGCATCCCCAAGGGCTACCCCGACT
ACGTGCTGCACAAGATGGTCACCGTGATGAAGAACGGCGAGGAGGTGAAGATCTCCAAGCGTGCCGGCTCGTATGTGACC
GTGCGCGACCTGATCGAGTGGTCAAACGGCGGCGATGAAACCATTCGCGGCTGCCTGGACGCAGGCGTGGCCGACTGGCC
CGAGCACTTCACGCGCGGGCGCGATGCCGTGCGCTTCTTCCTGCTGTCGCGCAAGGCTGACACGGAGTTCGTGTTCGACG
TGGACCTCGCGCTCAAGCAGAACGACGAGAACCCGGTGTACTACGTGCAGTACGCCCACGCGCGCATCTGCTCGATCTTC
GAATCGTGGGGCGGCGCCGACTGGGAAAGCCGCCTGGCCGAACTGGCCGGCACCGACCTGGCCGCCGTCACCGGTGCCGA
CGCGAGCCCGCAGGCACTGGCGCTGGGCCAGCGCCTGGCCGAGTTCCCCGAGATGCTGGCCGCCGCTGCGGGCGAACTGG
CGCCGCACGCCGTTGCGTTCTACCTGCGCGACCTGGCCGGGGATTTCCACGCGTTCTACAACGCCGACCGCGTGCTGGTC
GATGACGAAGCCGTCAAGCGTGCCCGCCTGGCACTGCTGGCCGCCACGCGCCAGGTGCTGCGCAATGGCCTGGCGGTGAT
CGGCGTCTCGGCGCCGCGCCGCATGTAA

Upstream 100 bases:

>100_bases
TTCGGCGTTCCGCACGTGCTCTCTGCCGGCCATTGCCGGTTTGGCTGCGCGGGCCGACGCACCGCCTGCCCGACTACCGC
CCAACAGGGCCTCGACACCC

Downstream 100 bases:

>100_bases
GTACGGAAGTCAAGGCACCGGCGTGCGATCGGGCCGGCTGGCGGGGCAGTGTTGCTCCGCAATGTGGCCGGCGCCGCCGC
GGGCGGCGCTGGCACTATAA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 595; Mature: 595

Protein sequence:

>595_residues
MLPVQTSNLAAAFTDAVRALAPADAALPAVTFERPKAAAHGDLACNIAMQVARALKSNPRELAQRIVAMVQADPRAAELV
AGMEIAGPGFINLRLTPAAKADVLRAVLSEGDGYGAQERGMHGNVLVEFVSANPTGPLHVGHGRQAALGDALANLLSWQG
YDVHREFYYNDAGVQIQNLAVSVQARTRGFKPGDANWPEAAYNGDYIGDIAADFLAGKTVSASDGEPVTASGNPEDLDSI
RKFAVTYLRNEQDIDLQAFGVKFDHYYLESSLYTDGRVEAAVQGLVGKGKTYESEGALWLRTTDDGDDKDRVMKKTDGTY
TYFVPDVAYHTTKWERGFTKVINVQGSDHHGTIARVRAGLQGLDIGIPKGYPDYVLHKMVTVMKNGEEVKISKRAGSYVT
VRDLIEWSNGGDETIRGCLDAGVADWPEHFTRGRDAVRFFLLSRKADTEFVFDVDLALKQNDENPVYYVQYAHARICSIF
ESWGGADWESRLAELAGTDLAAVTGADASPQALALGQRLAEFPEMLAAAAGELAPHAVAFYLRDLAGDFHAFYNADRVLV
DDEAVKRARLALLAATRQVLRNGLAVIGVSAPRRM

Sequences:

>Translated_595_residues
MLPVQTSNLAAAFTDAVRALAPADAALPAVTFERPKAAAHGDLACNIAMQVARALKSNPRELAQRIVAMVQADPRAAELV
AGMEIAGPGFINLRLTPAAKADVLRAVLSEGDGYGAQERGMHGNVLVEFVSANPTGPLHVGHGRQAALGDALANLLSWQG
YDVHREFYYNDAGVQIQNLAVSVQARTRGFKPGDANWPEAAYNGDYIGDIAADFLAGKTVSASDGEPVTASGNPEDLDSI
RKFAVTYLRNEQDIDLQAFGVKFDHYYLESSLYTDGRVEAAVQGLVGKGKTYESEGALWLRTTDDGDDKDRVMKKTDGTY
TYFVPDVAYHTTKWERGFTKVINVQGSDHHGTIARVRAGLQGLDIGIPKGYPDYVLHKMVTVMKNGEEVKISKRAGSYVT
VRDLIEWSNGGDETIRGCLDAGVADWPEHFTRGRDAVRFFLLSRKADTEFVFDVDLALKQNDENPVYYVQYAHARICSIF
ESWGGADWESRLAELAGTDLAAVTGADASPQALALGQRLAEFPEMLAAAAGELAPHAVAFYLRDLAGDFHAFYNADRVLV
DDEAVKRARLALLAATRQVLRNGLAVIGVSAPRRM
>Mature_595_residues
MLPVQTSNLAAAFTDAVRALAPADAALPAVTFERPKAAAHGDLACNIAMQVARALKSNPRELAQRIVAMVQADPRAAELV
AGMEIAGPGFINLRLTPAAKADVLRAVLSEGDGYGAQERGMHGNVLVEFVSANPTGPLHVGHGRQAALGDALANLLSWQG
YDVHREFYYNDAGVQIQNLAVSVQARTRGFKPGDANWPEAAYNGDYIGDIAADFLAGKTVSASDGEPVTASGNPEDLDSI
RKFAVTYLRNEQDIDLQAFGVKFDHYYLESSLYTDGRVEAAVQGLVGKGKTYESEGALWLRTTDDGDDKDRVMKKTDGTY
TYFVPDVAYHTTKWERGFTKVINVQGSDHHGTIARVRAGLQGLDIGIPKGYPDYVLHKMVTVMKNGEEVKISKRAGSYVT
VRDLIEWSNGGDETIRGCLDAGVADWPEHFTRGRDAVRFFLLSRKADTEFVFDVDLALKQNDENPVYYVQYAHARICSIF
ESWGGADWESRLAELAGTDLAAVTGADASPQALALGQRLAEFPEMLAAAAGELAPHAVAFYLRDLAGDFHAFYNADRVLV
DDEAVKRARLALLAATRQVLRNGLAVIGVSAPRRM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=629, Percent_Identity=24.3243243243243, Blast_Score=116, Evalue=6e-26,
Organism=Escherichia coli, GI1788184, Length=615, Percent_Identity=27.6422764227642, Blast_Score=144, Evalue=2e-35,
Organism=Drosophila melanogaster, GI18859963, Length=622, Percent_Identity=23.1511254019293, Blast_Score=105, Evalue=7e-23,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 64495; Mature: 64495

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPVQTSNLAAAFTDAVRALAPADAALPAVTFERPKAAAHGDLACNIAMQVARALKSNPR
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHCCHH
ELAQRIVAMVQADPRAAELVAGMEIAGPGFINLRLTPAAKADVLRAVLSEGDGYGAQERG
HHHHHHHHHHCCCCHHHHHHHCCEECCCCEEEEEECCCHHHHHHHHHHHCCCCCCCHHCC
MHGNVLVEFVSANPTGPLHVGHGRQAALGDALANLLSWQGYDVHREFYYNDAGVQIQNLA
CCCCEEEEEEECCCCCCEEECCCCHHHHHHHHHHHHCCCCCCEEHEEEECCCCCEEEEEE
VSVQARTRGFKPGDANWPEAAYNGDYIGDIAADFLAGKTVSASDGEPVTASGNPEDLDSI
EEEEHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHH
RKFAVTYLRNEQDIDLQAFGVKFDHYYLESSLYTDGRVEAAVQGLVGKGKTYESEGALWL
HHHHHHHHCCCCCCCEEEEEEEEEHEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEE
RTTDDGDDKDRVMKKTDGTYTYFVPDVAYHTTKWERGFTKVINVQGSDHHGTIARVRAGL
EECCCCCCHHHHHHHCCCEEEEEECCHHHHCCHHHCCCEEEEEECCCCCCCHHHHHHHCC
QGLDIGIPKGYPDYVLHKMVTVMKNGEEVKISKRAGSYVTVRDLIEWSNGGDETIRGCLD
CCCEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEHHHHHHHCCCCHHHHHHHHH
AGVADWPEHFTRGRDAVRFFLLSRKADTEFVFDVDLALKQNDENPVYYVQYAHARICSIF
CCCCCCHHHHHCCHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCEEEEEEHHHHHHHHH
ESWGGADWESRLAELAGTDLAAVTGADASPQALALGQRLAEFPEMLAAAAGELAPHAVAF
HHCCCCCHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
YLRDLAGDFHAFYNADRVLVDDEAVKRARLALLAATRQVLRNGLAVIGVSAPRRM
HHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
>Mature Secondary Structure
MLPVQTSNLAAAFTDAVRALAPADAALPAVTFERPKAAAHGDLACNIAMQVARALKSNPR
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHCCHH
ELAQRIVAMVQADPRAAELVAGMEIAGPGFINLRLTPAAKADVLRAVLSEGDGYGAQERG
HHHHHHHHHHCCCCHHHHHHHCCEECCCCEEEEEECCCHHHHHHHHHHHCCCCCCCHHCC
MHGNVLVEFVSANPTGPLHVGHGRQAALGDALANLLSWQGYDVHREFYYNDAGVQIQNLA
CCCCEEEEEEECCCCCCEEECCCCHHHHHHHHHHHHCCCCCCEEHEEEECCCCCEEEEEE
VSVQARTRGFKPGDANWPEAAYNGDYIGDIAADFLAGKTVSASDGEPVTASGNPEDLDSI
EEEEHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHH
RKFAVTYLRNEQDIDLQAFGVKFDHYYLESSLYTDGRVEAAVQGLVGKGKTYESEGALWL
HHHHHHHHCCCCCCCEEEEEEEEEHEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEE
RTTDDGDDKDRVMKKTDGTYTYFVPDVAYHTTKWERGFTKVINVQGSDHHGTIARVRAGL
EECCCCCCHHHHHHHCCCEEEEEECCHHHHCCHHHCCCEEEEEECCCCCCCHHHHHHHCC
QGLDIGIPKGYPDYVLHKMVTVMKNGEEVKISKRAGSYVTVRDLIEWSNGGDETIRGCLD
CCCEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEHHHHHHHCCCCHHHHHHHHH
AGVADWPEHFTRGRDAVRFFLLSRKADTEFVFDVDLALKQNDENPVYYVQYAHARICSIF
CCCCCCHHHHHCCHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCEEEEEEHHHHHHHHH
ESWGGADWESRLAELAGTDLAAVTGADASPQALALGQRLAEFPEMLAAAAGELAPHAVAF
HHCCCCCHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
YLRDLAGDFHAFYNADRVLVDDEAVKRARLALLAATRQVLRNGLAVIGVSAPRRM
HHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA