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The map label for this gene is mrdB [H]

Identifier: 73539786

GI number: 73539786

Start: 99742

End: 100884

Strand: Direct

Name: mrdB [H]

Synonym: Reut_A0080

Alternate gene names: 73539786

Gene position: 99742-100884 (Clockwise)

Preceding gene: 73539785

Following gene: 73539787

Centisome position: 2.62

GC content: 63.25

Gene sequence:

>1143_bases
ATGGACAAGCGTCGCGTCCTGTCGCTCATCAAGACGGCGTTTACCGGCTTTGACAAGCCGCTCGCGCTGATCGTGTTCCT
GTTGTTCGCCACCGGCATCGTGGCGCTGTATTCCGCCGCCATCGACATGCCGGGCCGGGTCGAAGACCAGCTGCGCAACA
TCCTGCTGTCGTACGTGGTGATGCTGGTGATCGCCTACCTGCCCACGCAGACGCTGATGCGGGTGGCCGTGCCGATCTAT
ACGGTCGGCGTGGCGCTGCTGATCGCGGTGGCCATGTTCGGCCTGATCCGCAAGGGTGCGCGGCGCTGGCTCAATGTCGG
CATGGTGATCCAGCCGTCAGAGATCATGAAGATCTCCATGCCGCTGATGCTCGCGTGGTACTTCCAGAAACGCGAGGGTG
TGGTCCGATGGTATGACTTCGTGGTGGCTCTGGCGCTGCTGCTGATCCCGGTCGGCCTGATCGCCAAGCAGCCCGACCTC
GGCACCGCGCTGCTGGTGATGGCGGCCGGTGTCTACGTGATCTACTTCGCGGGACTGTCCTGGCGCATCATCCTGCCGCT
GCTGGGCGTCCTGGTGGTCGCGGTCTCGCTGCTGATCACGTACCAGAACGATATCTGCGCGCCGGGCGTGAACTGGCCGA
TCCTGCACGACTACCAGCAGCATCGCGTGTGCACGCTGCTCGATCCGACCACCGATCCGCTCGGCAAAGGCTTCCACACG
ATCCAGTCGATCATCGCGATCGGCTCGGGCGGCGTCGATGGCAAGGGCTGGCTCAAGGGCACCCAGACCCACCTCGAGTT
CATCCCGGAAAAGCACACCGACTTCATCTTCGCGGTGTACTCCGAGGAATTCGGCCTGATCGGCAACGCTATCCTGCTGG
TGCTGTACCTGCTGCTGATCTTCCGTGGGCTGTTCATCGCGGCCAATGCCCCGACGCTGTTTTCGCGGCTGCTGGCGGGC
TCGATCACGCTGATCTTCTTCACCTATGCCTTCGTCAATATGGGCATGGTGAGCGGCATCCTGCCCGTGGTGGGCGTGCC
GCTGCCGCTGATGAGCTACGGCGGCACGGCGCTGGTGACGCTGGGTGCGGGCATCGGCATCCTGATGGCGATTTCCCGAC
AGAAACGGCTGATCCAGACGTAA

Upstream 100 bases:

>100_bases
CCCCTGTTGCGGCCAAGGCGCCTGCACCGAAACCCCGCGTCAAGCCCGTTGCTGCCACCCCGGCGACTGGCCCCGACGTT
ACCCGCTGAAGGAGACGCGC

Downstream 100 bases:

>100_bases
TACAGATGGGCAGACAGAAAGGGGCGGGGCGTGAATGCCCCGCTTTGCTACACTGCCATCCAAATTTCTCTCGGTTCGAA
GCCCATGAACGCCCAAGACG

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MDKRRVLSLIKTAFTGFDKPLALIVFLLFATGIVALYSAAIDMPGRVEDQLRNILLSYVVMLVIAYLPTQTLMRVAVPIY
TVGVALLIAVAMFGLIRKGARRWLNVGMVIQPSEIMKISMPLMLAWYFQKREGVVRWYDFVVALALLLIPVGLIAKQPDL
GTALLVMAAGVYVIYFAGLSWRIILPLLGVLVVAVSLLITYQNDICAPGVNWPILHDYQQHRVCTLLDPTTDPLGKGFHT
IQSIIAIGSGGVDGKGWLKGTQTHLEFIPEKHTDFIFAVYSEEFGLIGNAILLVLYLLLIFRGLFIAANAPTLFSRLLAG
SITLIFFTYAFVNMGMVSGILPVVGVPLPLMSYGGTALVTLGAGIGILMAISRQKRLIQT

Sequences:

>Translated_380_residues
MDKRRVLSLIKTAFTGFDKPLALIVFLLFATGIVALYSAAIDMPGRVEDQLRNILLSYVVMLVIAYLPTQTLMRVAVPIY
TVGVALLIAVAMFGLIRKGARRWLNVGMVIQPSEIMKISMPLMLAWYFQKREGVVRWYDFVVALALLLIPVGLIAKQPDL
GTALLVMAAGVYVIYFAGLSWRIILPLLGVLVVAVSLLITYQNDICAPGVNWPILHDYQQHRVCTLLDPTTDPLGKGFHT
IQSIIAIGSGGVDGKGWLKGTQTHLEFIPEKHTDFIFAVYSEEFGLIGNAILLVLYLLLIFRGLFIAANAPTLFSRLLAG
SITLIFFTYAFVNMGMVSGILPVVGVPLPLMSYGGTALVTLGAGIGILMAISRQKRLIQT
>Mature_380_residues
MDKRRVLSLIKTAFTGFDKPLALIVFLLFATGIVALYSAAIDMPGRVEDQLRNILLSYVVMLVIAYLPTQTLMRVAVPIY
TVGVALLIAVAMFGLIRKGARRWLNVGMVIQPSEIMKISMPLMLAWYFQKREGVVRWYDFVVALALLLIPVGLIAKQPDL
GTALLVMAAGVYVIYFAGLSWRIILPLLGVLVVAVSLLITYQNDICAPGVNWPILHDYQQHRVCTLLDPTTDPLGKGFHT
IQSIIAIGSGGVDGKGWLKGTQTHLEFIPEKHTDFIFAVYSEEFGLIGNAILLVLYLLLIFRGLFIAANAPTLFSRLLAG
SITLIFFTYAFVNMGMVSGILPVVGVPLPLMSYGGTALVTLGAGIGILMAISRQKRLIQT

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=346, Percent_Identity=50.5780346820809, Blast_Score=298, Evalue=3e-82,
Organism=Escherichia coli, GI1786277, Length=380, Percent_Identity=30.7894736842105, Blast_Score=162, Evalue=5e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41598; Mature: 41598

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKRRVLSLIKTAFTGFDKPLALIVFLLFATGIVALYSAAIDMPGRVEDQLRNILLSYVV
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
MLVIAYLPTQTLMRVAVPIYTVGVALLIAVAMFGLIRKGARRWLNVGMVIQPSEIMKISM
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHH
PLMLAWYFQKREGVVRWYDFVVALALLLIPVGLIAKQPDLGTALLVMAAGVYVIYFAGLS
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCH
WRIILPLLGVLVVAVSLLITYQNDICAPGVNWPILHDYQQHRVCTLLDPTTDPLGKGFHT
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCEEEEECCCCCCCCCHHHH
IQSIIAIGSGGVDGKGWLKGTQTHLEFIPEKHTDFIFAVYSEEFGLIGNAILLVLYLLLI
HHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
FRGLFIAANAPTLFSRLLAGSITLIFFTYAFVNMGMVSGILPVVGVPLPLMSYGGTALVT
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEH
LGAGIGILMAISRQKRLIQT
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDKRRVLSLIKTAFTGFDKPLALIVFLLFATGIVALYSAAIDMPGRVEDQLRNILLSYVV
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
MLVIAYLPTQTLMRVAVPIYTVGVALLIAVAMFGLIRKGARRWLNVGMVIQPSEIMKISM
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHH
PLMLAWYFQKREGVVRWYDFVVALALLLIPVGLIAKQPDLGTALLVMAAGVYVIYFAGLS
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCH
WRIILPLLGVLVVAVSLLITYQNDICAPGVNWPILHDYQQHRVCTLLDPTTDPLGKGFHT
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCEEEEECCCCCCCCCHHHH
IQSIIAIGSGGVDGKGWLKGTQTHLEFIPEKHTDFIFAVYSEEFGLIGNAILLVLYLLLI
HHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
FRGLFIAANAPTLFSRLLAGSITLIFFTYAFVNMGMVSGILPVVGVPLPLMSYGGTALVT
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEH
LGAGIGILMAISRQKRLIQT
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]