| Definition | Ralstonia eutropha JMP134 chromosome chromosome 2, complete sequence. |
|---|---|
| Accession | NC_007348 |
| Length | 2,726,152 |
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The map label for this gene is hutH [H]
Identifier: 73539459
GI number: 73539459
Start: 2458187
End: 2459743
Strand: Direct
Name: hutH [H]
Synonym: Reut_B5637
Alternate gene names: 73539459
Gene position: 2458187-2459743 (Clockwise)
Preceding gene: 73539458
Following gene: 73539460
Centisome position: 90.17
GC content: 64.55
Gene sequence:
>1557_bases ATGTCATATCAAGCAAACCAGCCGGCCACCGCCCTCCATCTGCAACCGGGTGAGCTGACGCTCGCGCAACTGCGTGCCGT ACATCAGTATCCCGTCAGGATCATGCTCGACGAGCGTGCCTTCGCGGCCATCGATCAAAGCGTGGCATGCGTCGAGAGCG TCATCTCCGAGGGCCGCACTGCCTATGGCATCAACACCGGCTTCGGCCTGCTGGCACAGACGCGCATTGCGCGCGAGGAC CTGGAAAGCCTGCAGCGTTCGCTGGTGCTCTCGCATGCGGCCGGCGTAGGCGAGCCAATCGACGACGCCCTGGTGCGCCT GATCATGGTGCTCAAGATCAACAGCCTGGCGCGGGGACTGTCCGGCATCCGTCGCAAAGTCATCGACGCGCTGACCACTC TGGTGAACGCCGAGGTGTACCCTCGCATCCCGCTGAAGGGGTCGGTCGGCGCGTCGGGCGATCTGGCGCCACTTGCCCAC ATGTCGCTGCTGCTGCTCGGCGAAGGCCAGGCACGCTATCGCGGCGAATGGCTGCCCGCACGTGAAGCGCTTGCCCTTGC CGATCTGCAACCGCTCACGCTTGCAGCCAAGGAAGGGCTTGCGTTGCTCAATGGCACGCAGGTCTCCACTGCGTACGCTC TGCAGGGATTGTTCCAGGCAGAAGACCTGTTTGCCGCGGCGAGTGTCTGCGGGGCGCTGACCGTCGAGGCATCGCTTGGC TCGCGCGCGCCGTTCGATCCACGTATCCACGCCGCGCGCGGCCAGCGAGGGCAGATCGATTCGGCGGCGGTCTATCGTCA CCTGCTGGGGCCGACCAGCGAGGTCGGTCAGTCCCATGCAAGCTGCGAAAAGGTCCAGGATCCCTATTCCCTGCGCTGTC AGCCCCAAGTCATGGGCGCCTGCCTGACGCAGATCCGCAATGCGGCGGACGTGCTTGCCGTCGAGGCGAACTCGGTTTCC GACAATCCCCTGGTGTTTGCGCAGGAAGGGGACATCATCTCGGGCGGCAACTTCCACGCGGAGCCGGTGGCCATGGCAGC GGACAACCTCGCGCTGGCACTGGCTGAGATTGGCGCGTTGAGCGAGCGGCGCATTTCACTGATGATGGACAAGCACATGT CGCAGTTGCCGGCGTTCCTTGTCGCCAACGGCGGCGTTAACTCCGGCTTCATGATCGCGCAGGTCACGGCGGCTGCCCTG GCGTCGGACAACAAGGCGCTCGCACATCCTGCCAGCGTTGACAGCCTGCCGACCTCCGCGAATCAGGAAGACCACGTGTC CATGGCTCCCAACGCCGGAAAGCGTCTTTGGGAGATGGCCAGCAACGTGAAGGGCATCATTGCCATCGAATGGCTCGCTG CCTGCCAGGGACTCGATTTCCGCGAGGGGGCAAAGTCTTCTGAGGCGCTGGAGCGCGCGCGTGGGCTTCTGCGACAGTCA GTGCCGTTCTACGACAAGGACCGCTACTTCGCTCCGGACATTGAAGGGGCCAGCGCACTGATCGCCGAGCGCCACCTCAC GGCCCTGTTGCCTGCGGGCATGCTGCCAAGCCTCTAA
Upstream 100 bases:
>100_bases TGATGCGCCATGCCGATGCTGGCTACCAGATCGCCATCGACTGCGCACGCGAAGCCGGTCTGAACCTGCCGATGCTCGGC ACCTCCAAGTGAACCTGAAC
Downstream 100 bases:
>100_bases GAAGAACGCAAAACGCTTACACCGGCGCTGAGCGGGCTAAGACCTGCGCGCCATGGGACTGCCGGTCCCCATCTCGATAT CTTTCTGGAGACAGCTTGAA
Product: histidine ammonia-lyase
Products: NA
Alternate protein names: Histidase [H]
Number of amino acids: Translated: 518; Mature: 517
Protein sequence:
>518_residues MSYQANQPATALHLQPGELTLAQLRAVHQYPVRIMLDERAFAAIDQSVACVESVISEGRTAYGINTGFGLLAQTRIARED LESLQRSLVLSHAAGVGEPIDDALVRLIMVLKINSLARGLSGIRRKVIDALTTLVNAEVYPRIPLKGSVGASGDLAPLAH MSLLLLGEGQARYRGEWLPAREALALADLQPLTLAAKEGLALLNGTQVSTAYALQGLFQAEDLFAAASVCGALTVEASLG SRAPFDPRIHAARGQRGQIDSAAVYRHLLGPTSEVGQSHASCEKVQDPYSLRCQPQVMGACLTQIRNAADVLAVEANSVS DNPLVFAQEGDIISGGNFHAEPVAMAADNLALALAEIGALSERRISLMMDKHMSQLPAFLVANGGVNSGFMIAQVTAAAL ASDNKALAHPASVDSLPTSANQEDHVSMAPNAGKRLWEMASNVKGIIAIEWLAACQGLDFREGAKSSEALERARGLLRQS VPFYDKDRYFAPDIEGASALIAERHLTALLPAGMLPSL
Sequences:
>Translated_518_residues MSYQANQPATALHLQPGELTLAQLRAVHQYPVRIMLDERAFAAIDQSVACVESVISEGRTAYGINTGFGLLAQTRIARED LESLQRSLVLSHAAGVGEPIDDALVRLIMVLKINSLARGLSGIRRKVIDALTTLVNAEVYPRIPLKGSVGASGDLAPLAH MSLLLLGEGQARYRGEWLPAREALALADLQPLTLAAKEGLALLNGTQVSTAYALQGLFQAEDLFAAASVCGALTVEASLG SRAPFDPRIHAARGQRGQIDSAAVYRHLLGPTSEVGQSHASCEKVQDPYSLRCQPQVMGACLTQIRNAADVLAVEANSVS DNPLVFAQEGDIISGGNFHAEPVAMAADNLALALAEIGALSERRISLMMDKHMSQLPAFLVANGGVNSGFMIAQVTAAAL ASDNKALAHPASVDSLPTSANQEDHVSMAPNAGKRLWEMASNVKGIIAIEWLAACQGLDFREGAKSSEALERARGLLRQS VPFYDKDRYFAPDIEGASALIAERHLTALLPAGMLPSL >Mature_517_residues SYQANQPATALHLQPGELTLAQLRAVHQYPVRIMLDERAFAAIDQSVACVESVISEGRTAYGINTGFGLLAQTRIAREDL ESLQRSLVLSHAAGVGEPIDDALVRLIMVLKINSLARGLSGIRRKVIDALTTLVNAEVYPRIPLKGSVGASGDLAPLAHM SLLLLGEGQARYRGEWLPAREALALADLQPLTLAAKEGLALLNGTQVSTAYALQGLFQAEDLFAAASVCGALTVEASLGS RAPFDPRIHAARGQRGQIDSAAVYRHLLGPTSEVGQSHASCEKVQDPYSLRCQPQVMGACLTQIRNAADVLAVEANSVSD NPLVFAQEGDIISGGNFHAEPVAMAADNLALALAEIGALSERRISLMMDKHMSQLPAFLVANGGVNSGFMIAQVTAAALA SDNKALAHPASVDSLPTSANQEDHVSMAPNAGKRLWEMASNVKGIIAIEWLAACQGLDFREGAKSSEALERARGLLRQSV PFYDKDRYFAPDIEGASALIAERHLTALLPAGMLPSL
Specific function: Unknown
COG id: COG2986
COG function: function code E; Histidine ammonia-lyase
Gene ontology:
Cell location: Cytoplasm (Potential) [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the PAL/histidase family [H]
Homologues:
Organism=Homo sapiens, GI4504333, Length=507, Percent_Identity=43.5897435897436, Blast_Score=409, Evalue=1e-114, Organism=Caenorhabditis elegans, GI17567831, Length=466, Percent_Identity=43.5622317596566, Blast_Score=361, Evalue=1e-100,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005921 - InterPro: IPR008948 - InterPro: IPR001106 - InterPro: IPR022313 [H]
Pfam domain/function: PF00221 PAL [H]
EC number: =4.3.1.3 [H]
Molecular weight: Translated: 54912; Mature: 54781
Theoretical pI: Translated: 5.78; Mature: 5.78
Prosite motif: PS00488 PAL_HISTIDASE ; PS00213 LIPOCALIN
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 3.7 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSYQANQPATALHLQPGELTLAQLRAVHQYPVRIMLDERAFAAIDQSVACVESVISEGRT CCCCCCCCCEEEEECCCCHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHCCCE AYGINTGFGLLAQTRIAREDLESLQRSLVLSHAAGVGEPIDDALVRLIMVLKINSLARGL EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH SGIRRKVIDALTTLVNAEVYPRIPLKGSVGASGDLAPLAHMSLLLLGEGQARYRGEWLPA HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHEEEEECCCHHHCCCCCCH REALALADLQPLTLAAKEGLALLNGTQVSTAYALQGLFQAEDLFAAASVCGALTVEASLG HHHHHHHCCCCHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCC SRAPFDPRIHAARGQRGQIDSAAVYRHLLGPTSEVGQSHASCEKVQDPYSLRCQPQVMGA CCCCCCCCEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHH CLTQIRNAADVLAVEANSVSDNPLVFAQEGDIISGGNFHAEPVAMAADNLALALAEIGAL HHHHHHCHHHEEEEECCCCCCCCEEEEECCCEECCCCCCCCCHHHHHHHHHHHHHHHHCH SERRISLMMDKHMSQLPAFLVANGGVNSGFMIAQVTAAALASDNKALAHPASVDSLPTSA HHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC NQEDHVSMAPNAGKRLWEMASNVKGIIAIEWLAACQGLDFREGAKSSEALERARGLLRQS CCCCCEEECCCHHHHHHHHHHCCCEEEEEHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHC VPFYDKDRYFAPDIEGASALIAERHLTALLPAGMLPSL CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC >Mature Secondary Structure SYQANQPATALHLQPGELTLAQLRAVHQYPVRIMLDERAFAAIDQSVACVESVISEGRT CCCCCCCCEEEEECCCCHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHCCCE AYGINTGFGLLAQTRIAREDLESLQRSLVLSHAAGVGEPIDDALVRLIMVLKINSLARGL EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH SGIRRKVIDALTTLVNAEVYPRIPLKGSVGASGDLAPLAHMSLLLLGEGQARYRGEWLPA HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHEEEEECCCHHHCCCCCCH REALALADLQPLTLAAKEGLALLNGTQVSTAYALQGLFQAEDLFAAASVCGALTVEASLG HHHHHHHCCCCHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCC SRAPFDPRIHAARGQRGQIDSAAVYRHLLGPTSEVGQSHASCEKVQDPYSLRCQPQVMGA CCCCCCCCEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHH CLTQIRNAADVLAVEANSVSDNPLVFAQEGDIISGGNFHAEPVAMAADNLALALAEIGAL HHHHHHCHHHEEEEECCCCCCCCEEEEECCCEECCCCCCCCCHHHHHHHHHHHHHHHHCH SERRISLMMDKHMSQLPAFLVANGGVNSGFMIAQVTAAALASDNKALAHPASVDSLPTSA HHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC NQEDHVSMAPNAGKRLWEMASNVKGIIAIEWLAACQGLDFREGAKSSEALERARGLLRQS CCCCCEEECCCHHHHHHHHHHCCCEEEEEHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHC VPFYDKDRYFAPDIEGASALIAERHLTALLPAGMLPSL CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA