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The map label for this gene is flhA [H]

Identifier: 73539438

GI number: 73539438

Start: 2435007

End: 2437088

Strand: Direct

Name: flhA [H]

Synonym: Reut_B5616

Alternate gene names: 73539438

Gene position: 2435007-2437088 (Clockwise)

Preceding gene: 73539437

Following gene: 73539439

Centisome position: 89.32

GC content: 65.8

Gene sequence:

>2082_bases
ATGAACGCTCTGAACTCCCTGTTGAAACTGCCAGGCCTGCGCAATGCGGGCCAGCTCAAGGCAATGACCGGGCCGATGCT
GATCGTCATGATCCTCGGCATGATGATCCTGCCGCTGCCGGCGTTCGTGCTGGACCTGCTGTTCACGTTCAATATCGCAC
TGGCCATCATGGTGCTGCTGGTCAGCATGTACACGCAGAAGCCGCTCGATTTCGCGGCGTTTCCTGCCGTGCTGCTGTTC
ACCACGCTGTTGCGTCTGTCGCTGAACGTGGCGTCCACGCGCGTGGTGCTGCTCGAAGGCCATACCGGCCCGGACGCGGC
CGGCAAGGTGATCGAGGCGTTCGGTCACTTCCTGGTCGGTGGCAACTTCGCCGTCGGTATCGTGGTGTTCGCGATCCTGG
TGGTGATCAACTTCATGGTGATTACCAAGGGCGCGGGCCGTATCGCCGAAGTGGGCGCGCGTTTCATGCTGGACTCCATG
CCCGGCAAGCAGATGTCGATCGACGCCGACCTGAACGCCGGCCTGATCAATGAAGATCAGGCCAAGAAGCGCCGCGCGGA
AGTCGCGCAGGAATCCGACTTCTACGGCGCCATGGACGGTGCCAGCAAGTTCGTGCGCGGCGATGCCGTCGCCGGCCTGC
TGATCATGTTCATCAACGTCGCCGCCGGCATGGTGGTCGGCATGGTCCAGCACGACCTGGACTTCGGCACCGCCGTGCAC
AACTACACGCTGCTGACCATTGGCGATGGCCTGGTCGCGCAGATTCCTGCGCTGGTGATTTCGACCGCGGCCGGCGTGAT
CGTGTCGCGCGTGTCGAACGAGCAGGACGTGGGCGAGCAGCTCACGGGCCAGCTTTTCGCCAATCCGCGCGTGCTGTACC
TGACCGCCGGCATCATCGGCATGATGGGCATCATCCCCGGCATGCCGCATTTCGCCTTCCTGGTGCTGGCCGGCAGCCTG
ATCTGGCTGGGCCGCTACCTGGCGCAGCGCGAGGCCACCGCGCAGCAGACCAAGCAGCGCGAGGAGCGCGCACCCGCCGC
CGCGCCGGAATCGACCGAAGCGAGCTGGGACGACGTCACGCTGGTGGACCCGCTCGGCATGGAAGTGGGCTACCGCCTGA
TCACGCTGGTGGACCGCGCGCAAGACGGCGAACTGCTGGGCCGCATCAAGAGCATCCGCAAGAAGGTGGCGCAGGAAATC
GGCTTCCTGGTGCCGGTCGTGCATATCCGCGACAACCTGGAACTGAAGCCCAACGCCTACCGCATCACGCTCAAGGGCGT
GGAGATCGGGCGTGGCGAGGCCATGCCGGGACAGTGGATGGCAATCAACCCCGGGCAGGTCAGCGGTACGCTGCCGGGCA
CGGCCACGCGCGACCCGGCGTTCGGCCTGGAAGCCGTGTGGATCGACGCCGGCATGAAGGAGCAGGCGCAGGCGTTCGGC
TACACCGTGGTGGATGCGAGCACCGTGGTCGCCACGCACCTGAACCACCTGATCCACATGCACGCCGCCGAACTGCTGGG
CCGCCAGGAAGTGCAGATGCTGCTCGACCGCATCGCCAAGGAAGCGCCCAAGCTGACCGAGGACCTCGTGCCCAAGACCA
TCTCGCTGACGGCGCTGCAGAAGATCCTGCAGAACCTGCTGGACGAAGGCGTGCCGATCCGCGACATGCGCACCATCCTG
GATGTGCTCGCCGAGCATGCGCCGAAGATCAGCGATCCGAACGAACTGACCGCACTGGTGCGCCAGGCGCTGGGCCGCGC
GATTACGCAGCAGCTGTTCCCCAATGGCGCCGACCTGCAGGTGATCGGCCTCGACGCGGGCCTGGAGCGCGTGCTGTCGC
AGGCGCTGACCAATGGCGGCGGCATCGAGCCGGGCCTCGCCGACGCGCTGCTGCAGCAGACGCAGGGCGCTGTGAGCCGC
CAGGAGCAGATGGGCCTGGATCCGGTGCTGCTGGTGCCGTCGCAACTGCGCCCGCTGATGGCGCGCTTCCTGCGTCGCAC
CATGCCGCAGCTGAGGGTGTTGTCCCATGCCGAAGTGCCGGACAACCGCAATATCCGCATTACCGCAATGATCGGTGCGT
GA

Upstream 100 bases:

>100_bases
TCTATCAACTGAAACACTGGCACTACTCGCAAGGCCCGCAGCCGTCGGCGCCCAGCGATCTCCTGGTGCCGGACGAACTC
GCCGTTCCGGAAAGCCGCGC

Downstream 100 bases:

>100_bases
GGAACGCAAGATGAGCGTAGCGAAATTCGTGGCGGCCAACGGCCGTGAAGCCATGCGCAAGGTGCGCGAAGCCATGGGAC
CCGATGCCGTGGTGCTGTCC

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 693; Mature: 693

Protein sequence:

>693_residues
MNALNSLLKLPGLRNAGQLKAMTGPMLIVMILGMMILPLPAFVLDLLFTFNIALAIMVLLVSMYTQKPLDFAAFPAVLLF
TTLLRLSLNVASTRVVLLEGHTGPDAAGKVIEAFGHFLVGGNFAVGIVVFAILVVINFMVITKGAGRIAEVGARFMLDSM
PGKQMSIDADLNAGLINEDQAKKRRAEVAQESDFYGAMDGASKFVRGDAVAGLLIMFINVAAGMVVGMVQHDLDFGTAVH
NYTLLTIGDGLVAQIPALVISTAAGVIVSRVSNEQDVGEQLTGQLFANPRVLYLTAGIIGMMGIIPGMPHFAFLVLAGSL
IWLGRYLAQREATAQQTKQREERAPAAAPESTEASWDDVTLVDPLGMEVGYRLITLVDRAQDGELLGRIKSIRKKVAQEI
GFLVPVVHIRDNLELKPNAYRITLKGVEIGRGEAMPGQWMAINPGQVSGTLPGTATRDPAFGLEAVWIDAGMKEQAQAFG
YTVVDASTVVATHLNHLIHMHAAELLGRQEVQMLLDRIAKEAPKLTEDLVPKTISLTALQKILQNLLDEGVPIRDMRTIL
DVLAEHAPKISDPNELTALVRQALGRAITQQLFPNGADLQVIGLDAGLERVLSQALTNGGGIEPGLADALLQQTQGAVSR
QEQMGLDPVLLVPSQLRPLMARFLRRTMPQLRVLSHAEVPDNRNIRITAMIGA

Sequences:

>Translated_693_residues
MNALNSLLKLPGLRNAGQLKAMTGPMLIVMILGMMILPLPAFVLDLLFTFNIALAIMVLLVSMYTQKPLDFAAFPAVLLF
TTLLRLSLNVASTRVVLLEGHTGPDAAGKVIEAFGHFLVGGNFAVGIVVFAILVVINFMVITKGAGRIAEVGARFMLDSM
PGKQMSIDADLNAGLINEDQAKKRRAEVAQESDFYGAMDGASKFVRGDAVAGLLIMFINVAAGMVVGMVQHDLDFGTAVH
NYTLLTIGDGLVAQIPALVISTAAGVIVSRVSNEQDVGEQLTGQLFANPRVLYLTAGIIGMMGIIPGMPHFAFLVLAGSL
IWLGRYLAQREATAQQTKQREERAPAAAPESTEASWDDVTLVDPLGMEVGYRLITLVDRAQDGELLGRIKSIRKKVAQEI
GFLVPVVHIRDNLELKPNAYRITLKGVEIGRGEAMPGQWMAINPGQVSGTLPGTATRDPAFGLEAVWIDAGMKEQAQAFG
YTVVDASTVVATHLNHLIHMHAAELLGRQEVQMLLDRIAKEAPKLTEDLVPKTISLTALQKILQNLLDEGVPIRDMRTIL
DVLAEHAPKISDPNELTALVRQALGRAITQQLFPNGADLQVIGLDAGLERVLSQALTNGGGIEPGLADALLQQTQGAVSR
QEQMGLDPVLLVPSQLRPLMARFLRRTMPQLRVLSHAEVPDNRNIRITAMIGA
>Mature_693_residues
MNALNSLLKLPGLRNAGQLKAMTGPMLIVMILGMMILPLPAFVLDLLFTFNIALAIMVLLVSMYTQKPLDFAAFPAVLLF
TTLLRLSLNVASTRVVLLEGHTGPDAAGKVIEAFGHFLVGGNFAVGIVVFAILVVINFMVITKGAGRIAEVGARFMLDSM
PGKQMSIDADLNAGLINEDQAKKRRAEVAQESDFYGAMDGASKFVRGDAVAGLLIMFINVAAGMVVGMVQHDLDFGTAVH
NYTLLTIGDGLVAQIPALVISTAAGVIVSRVSNEQDVGEQLTGQLFANPRVLYLTAGIIGMMGIIPGMPHFAFLVLAGSL
IWLGRYLAQREATAQQTKQREERAPAAAPESTEASWDDVTLVDPLGMEVGYRLITLVDRAQDGELLGRIKSIRKKVAQEI
GFLVPVVHIRDNLELKPNAYRITLKGVEIGRGEAMPGQWMAINPGQVSGTLPGTATRDPAFGLEAVWIDAGMKEQAQAFG
YTVVDASTVVATHLNHLIHMHAAELLGRQEVQMLLDRIAKEAPKLTEDLVPKTISLTALQKILQNLLDEGVPIRDMRTIL
DVLAEHAPKISDPNELTALVRQALGRAITQQLFPNGADLQVIGLDAGLERVLSQALTNGGGIEPGLADALLQQTQGAVSR
QEQMGLDPVLLVPSQLRPLMARFLRRTMPQLRVLSHAEVPDNRNIRITAMIGA

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=695, Percent_Identity=68.2014388489209, Blast_Score=935, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 74613; Mature: 74613

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALNSLLKLPGLRNAGQLKAMTGPMLIVMILGMMILPLPAFVLDLLFTFNIALAIMVLL
CCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSMYTQKPLDFAAFPAVLLFTTLLRLSLNVASTRVVLLEGHTGPDAAGKVIEAFGHFLVG
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHCC
GNFAVGIVVFAILVVINFMVITKGAGRIAEVGARFMLDSMPGKQMSIDADLNAGLINEDQ
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCHH
AKKRRAEVAQESDFYGAMDGASKFVRGDAVAGLLIMFINVAAGMVVGMVQHDLDFGTAVH
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCHHHH
NYTLLTIGDGLVAQIPALVISTAAGVIVSRVSNEQDVGEQLTGQLFANPRVLYLTAGIIG
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEHHHHHH
MMGIIPGMPHFAFLVLAGSLIWLGRYLAQREATAQQTKQREERAPAAAPESTEASWDDVT
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEE
LVDPLGMEVGYRLITLVDRAQDGELLGRIKSIRKKVAQEIGFLVPVVHIRDNLELKPNAY
EECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEECCCEE
RITLKGVEIGRGEAMPGQWMAINPGQVSGTLPGTATRDPAFGLEAVWIDAGMKEQAQAFG
EEEEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHCC
YTVVDASTVVATHLNHLIHMHAAELLGRQEVQMLLDRIAKEAPKLTEDLVPKTISLTALQ
EEEECHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHH
KILQNLLDEGVPIRDMRTILDVLAEHAPKISDPNELTALVRQALGRAITQQLFPNGADLQ
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEE
VIGLDAGLERVLSQALTNGGGIEPGLADALLQQTQGAVSRQEQMGLDPVLLVPSQLRPLM
EEECCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHH
ARFLRRTMPQLRVLSHAEVPDNRNIRITAMIGA
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MNALNSLLKLPGLRNAGQLKAMTGPMLIVMILGMMILPLPAFVLDLLFTFNIALAIMVLL
CCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSMYTQKPLDFAAFPAVLLFTTLLRLSLNVASTRVVLLEGHTGPDAAGKVIEAFGHFLVG
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHCC
GNFAVGIVVFAILVVINFMVITKGAGRIAEVGARFMLDSMPGKQMSIDADLNAGLINEDQ
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCHH
AKKRRAEVAQESDFYGAMDGASKFVRGDAVAGLLIMFINVAAGMVVGMVQHDLDFGTAVH
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCHHHH
NYTLLTIGDGLVAQIPALVISTAAGVIVSRVSNEQDVGEQLTGQLFANPRVLYLTAGIIG
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEHHHHHH
MMGIIPGMPHFAFLVLAGSLIWLGRYLAQREATAQQTKQREERAPAAAPESTEASWDDVT
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEE
LVDPLGMEVGYRLITLVDRAQDGELLGRIKSIRKKVAQEIGFLVPVVHIRDNLELKPNAY
EECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEECCCEE
RITLKGVEIGRGEAMPGQWMAINPGQVSGTLPGTATRDPAFGLEAVWIDAGMKEQAQAFG
EEEEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHCC
YTVVDASTVVATHLNHLIHMHAAELLGRQEVQMLLDRIAKEAPKLTEDLVPKTISLTALQ
EEEECHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHH
KILQNLLDEGVPIRDMRTILDVLAEHAPKISDPNELTALVRQALGRAITQQLFPNGADLQ
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEE
VIGLDAGLERVLSQALTNGGGIEPGLADALLQQTQGAVSRQEQMGLDPVLLVPSQLRPLM
EEECCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHH
ARFLRRTMPQLRVLSHAEVPDNRNIRITAMIGA
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]