Click here to switch to the map view.

The map label for this gene is bvgA [H]

Identifier: 73539358

GI number: 73539358

Start: 2337977

End: 2338606

Strand: Direct

Name: bvgA [H]

Synonym: Reut_B5536

Alternate gene names: 73539358

Gene position: 2337977-2338606 (Clockwise)

Preceding gene: 73539356

Following gene: 73539359

Centisome position: 85.76

GC content: 63.81

Gene sequence:

>630_bases
ATGGCTACCGTCCTGATCGTCGATGATCACCCCGCGTTGCGGCTGGTGATGAAATCGCAGCTTTCGCAATTGCTCGGCGT
GGAGCATATTCTTGAAGCCGACAACGGCCAGTGCGCGATCGAGGCCGTCCGCCAGCACAAGCCGGAACTGGTGATGCTCG
ACCTCGACATTCCGCGCATCGGCGGGCTCGATGTGGCGACAAGGGTGCGCGACATTCACCCTCCGGTACGCATCCTGGTC
GTGACGGCGCTCGATCCGGCGGTGTTCGTGTCGCGCTCGTGGCAGGCTGGCGTGCAGGGTTTCGTCAGCAAGACGCAGGA
CATCCGGGAAATCCTGCGCTCGGTGGAATCGGTACTGGCCGGCTACACGGTATTCCCGGCGCTGGCGCGGCGCGGCTCGC
CCGGCCCCGTGCTGTGCGGCGACGACGAGAACCTGCGCCGCCTGTCCGACAAGGAGCTGGTCGTGCTCAAGATGCTGGCG
CGTGGCCTCTCGTACAAGACCATCAGCGGCGAACTGTTTATCAGCAACAAGACCGTCAGTAGCTACAAGGCCCGCATCAT
GACCAAGCTGCAGGTCAGCTCGCTCGTGGAACTGGTGGATTTCGCCCGCCGCTGCCGGTTGGTCCAGTAG

Upstream 100 bases:

>100_bases
GCGCGTTTCCGAATGCACGTTTCCTATCCCGCGGTTGCCGGTCGCCCGGCGCCCGACGCATTCCTGACCGATACCGATAC
AGAGGAACAGACAGGCAAGC

Downstream 100 bases:

>100_bases
CAGTCGTTGCCGGTGGCGCAGGCTCAGGGAATTTGAATATCCCGTGCAGACGGCGCGCGTGCAAGGCGACACCGGCGCTG
GCACACTGTCGGTCTGATCA

Product: LuxR response regulator receiver

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MATVLIVDDHPALRLVMKSQLSQLLGVEHILEADNGQCAIEAVRQHKPELVMLDLDIPRIGGLDVATRVRDIHPPVRILV
VTALDPAVFVSRSWQAGVQGFVSKTQDIREILRSVESVLAGYTVFPALARRGSPGPVLCGDDENLRRLSDKELVVLKMLA
RGLSYKTISGELFISNKTVSSYKARIMTKLQVSSLVELVDFARRCRLVQ

Sequences:

>Translated_209_residues
MATVLIVDDHPALRLVMKSQLSQLLGVEHILEADNGQCAIEAVRQHKPELVMLDLDIPRIGGLDVATRVRDIHPPVRILV
VTALDPAVFVSRSWQAGVQGFVSKTQDIREILRSVESVLAGYTVFPALARRGSPGPVLCGDDENLRRLSDKELVVLKMLA
RGLSYKTISGELFISNKTVSSYKARIMTKLQVSSLVELVDFARRCRLVQ
>Mature_208_residues
ATVLIVDDHPALRLVMKSQLSQLLGVEHILEADNGQCAIEAVRQHKPELVMLDLDIPRIGGLDVATRVRDIHPPVRILVV
TALDPAVFVSRSWQAGVQGFVSKTQDIREILRSVESVLAGYTVFPALARRGSPGPVLCGDDENLRRLSDKELVVLKMLAR
GLSYKTISGELFISNKTVSSYKARIMTKLQVSSLVELVDFARRCRLVQ

Specific function: Member of the two-component regulatory system BvgS/BvgA. Activates the transcription of virulence genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786747, Length=207, Percent_Identity=31.8840579710145, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1788712, Length=212, Percent_Identity=33.9622641509434, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1788222, Length=206, Percent_Identity=29.126213592233, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1788521, Length=194, Percent_Identity=30.9278350515464, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790102, Length=209, Percent_Identity=29.6650717703349, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1787473, Length=186, Percent_Identity=29.0322580645161, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR011990
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23122; Mature: 22991

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATVLIVDDHPALRLVMKSQLSQLLGVEHILEADNGQCAIEAVRQHKPELVMLDLDIPRI
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCC
GGLDVATRVRDIHPPVRILVVTALDPAVFVSRSWQAGVQGFVSKTQDIREILRSVESVLA
CCCHHHHHHHHCCCCEEEEEEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYTVFPALARRGSPGPVLCGDDENLRRLSDKELVVLKMLARGLSYKTISGELFISNKTVS
HHHHHHHHHHCCCCCCEEECCCHHHHHCCCCHHHHHHHHHCCCCEEEECCEEEEECCCHH
SYKARIMTKLQVSSLVELVDFARRCRLVQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ATVLIVDDHPALRLVMKSQLSQLLGVEHILEADNGQCAIEAVRQHKPELVMLDLDIPRI
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCC
GGLDVATRVRDIHPPVRILVVTALDPAVFVSRSWQAGVQGFVSKTQDIREILRSVESVLA
CCCHHHHHHHHCCCCEEEEEEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYTVFPALARRGSPGPVLCGDDENLRRLSDKELVVLKMLARGLSYKTISGELFISNKTVS
HHHHHHHHHHCCCCCCEEECCCHHHHHCCCCHHHHHHHHHCCCCEEEECCEEEEECCCHH
SYKARIMTKLQVSSLVELVDFARRCRLVQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1791760; 12910271 [H]