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The map label for this gene is yegE [H]

Identifier: 73539343

GI number: 73539343

Start: 2317203

End: 2319194

Strand: Reverse

Name: yegE [H]

Synonym: Reut_B5521

Alternate gene names: 73539343

Gene position: 2319194-2317203 (Counterclockwise)

Preceding gene: 73539348

Following gene: 73539341

Centisome position: 85.07

GC content: 68.07

Gene sequence:

>1992_bases
ATGCCTGTCTTCTTGCCTTCGCTGAAAGCGCGTATCGCGTTGATCACCACGGTCCTGGCCGCGGTGTTCGGCACCGGCAT
CGTGCTGACGTCGCTGTTCGCCGCGCACCGCGACCTGCAAGACGTGCTGCAGGACGAGCAGGACTCCATCGTCAAGCTGT
CCGCGGACCAGCTCGACACCGCCATGGAAGACCGCATCATGCTGCTGAGGCAGCAGGCCGCGCAGCTTGGCGGCCTGTTT
GGCACGGCGCGCGGCGCGCAGGCCCCCGCGGCAATGGCGCAGGCGCTGGCGCAGGTACGACGCGCCATTCCGGTCCCCGG
TGCGTTCAATTCACTGATGGTCGTTGACGCGCGCGGCACGGCGCTCGGCGACAGCGGGATGGTCACCGAGGTGGGCGACC
GCACCTATTTCCGCGAAGCCGCACGCACGCTCGCCCCCGTGATCAGCCCGCCGATCCGCGCGCGCACCAACGACCGCCTC
GGCGTGATCGTCGCCGTGCCGGTCCTGTCCGCGCAGGGACGCTTTGCCGGCCTGGTCGGCGGCTGGCTCGACCTGGCTCG
TTCGAACTTCCTGGTCGAGGTGCTGCACAACCGGTTGGGCACCACGGGCTTCTACTGCCTGGTCTCCGCGGGCAGCCGCC
CCGTCTACATACAGCATCCCGACCCGACCCAGGCGCGCCAGCCAGCCCGCGCGATCGGCGACACCTGTGGCCAGGACGAT
CGCGCCGCCACGTTGGAATTCCTGACACCCACGCGCCCCGTAGTCTCGCGCTACCTGATGTCCACGACGGGCTGGGAACT
GGTGGCGCTGCTGCCCGCGCACGAGGCCTACGCGCCGCTGCACCGCATGCAGCAACGCTTCCTGATCCTGGCGGGGCTAG
CGCTGCTGCTGGTGGCCGCGTCCATCTGGCTGGCCGTGCGCCTTCTGCTGGCGCCGCTGACGCGGCTGCATGAAGTGGTC
AGGGACAGCGCGTCCGACCTGTCCGCGTTCGAGCGGCTGCCCGAGCGGCAGCACCGCGACGAGATCGGCGACCTTGCGCG
CGCCTTCACCCGCCTGATGCGCGACGTGCGCGAACGCCGCCAGGAACTGGACCGCAGCGAGCGGCGCCTGCGCGCGGTGA
CCGACACGCTGCCGTCGCTGCTGGCCTTCATCGACACGGACGAGCGCTATGTGTTCAACAACATTGCGTACGAGCACACC
TTCGGCCTGACGCTGGAGGAATTGCGCGGCAAGACCGTGCGCGAGGTATTGGGCGAAACGCGCTATGCCAGGGCCCAGCC
TTTCCTGCAGCGCGCACTGGCCGGCGCCGTGGTGACCTTCGAGTCCGAGGAAAACGAACCCGAGTACCACTGCATGGAAA
CCAGCTACCGGCCCGAATGGAGCGCGGATGGCAGCGAGGTGGTCGGCGTGCATATCCACGTGCAGGACATTACGCCACGC
AAGCTCGAAACCATGCGGCTATCGCATATTTCCAGCACGGACCACCTGACGCAGCTACTGAACCGCAGCGCGTTCGAAAG
CCGCCTGCAGGATGCCATGGCGCGATGCCGCGAAAGCGGCGGCATGATGGCGCTGCTGTACCTGGACATGGACCGCTTCA
AGGCGGTCAACGACATCCATGGCCATGCGGCCGGCGACCTGCTGCTGCAAGCCTTCGCCAAGCGCGTGCTAGGCTGCGTG
CGCAAGCAGGATGCGGTGGCGCGGCTCGGCGGCGACGAATTCGCGGTGATCCTCGAGAGCGTTGGCCATGCGGCCGCGGC
GCGCAGCGTGGCTACCGACATCCTGTGCGCGGTGGGCCAGCGCTTTCACTTCGAAGGCATGTTCGCCGATATCGACGTGA
GCATCGGCGTGGCGCTGTACGATGGCGGCCCGATGCAGGAGCGCGAACTGATGCGCCTGGCCGATGTGCTGCTCTACCGC
GCCAAGGGCGCGGGACGGGGCCGCTACGAGATCGGCCCCCCGGAACTGATTACCGCAGACAGCGCTCAGTGA

Upstream 100 bases:

>100_bases
CGCGTATGGTAGGGTAGTGCCGCAGGCGTTCCGCCGTGCGCATCGCCTGCCCGGACCCTGGCCCCCGCGCGGCAAGCCGA
ATTCCGAACATCGCCCCCGC

Downstream 100 bases:

>100_bases
ACCGTGCCGCGCGGTGTGCCGCCCGAGCCACCCGCGTCGCCAGCATCCTCACCGGCGTCACTGCCGGGCTCATACGGCAC
ATGGCGTCCGTCGCTGGACT

Product: hypothetical protein

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 663; Mature: 662

Protein sequence:

>663_residues
MPVFLPSLKARIALITTVLAAVFGTGIVLTSLFAAHRDLQDVLQDEQDSIVKLSADQLDTAMEDRIMLLRQQAAQLGGLF
GTARGAQAPAAMAQALAQVRRAIPVPGAFNSLMVVDARGTALGDSGMVTEVGDRTYFREAARTLAPVISPPIRARTNDRL
GVIVAVPVLSAQGRFAGLVGGWLDLARSNFLVEVLHNRLGTTGFYCLVSAGSRPVYIQHPDPTQARQPARAIGDTCGQDD
RAATLEFLTPTRPVVSRYLMSTTGWELVALLPAHEAYAPLHRMQQRFLILAGLALLLVAASIWLAVRLLLAPLTRLHEVV
RDSASDLSAFERLPERQHRDEIGDLARAFTRLMRDVRERRQELDRSERRLRAVTDTLPSLLAFIDTDERYVFNNIAYEHT
FGLTLEELRGKTVREVLGETRYARAQPFLQRALAGAVVTFESEENEPEYHCMETSYRPEWSADGSEVVGVHIHVQDITPR
KLETMRLSHISSTDHLTQLLNRSAFESRLQDAMARCRESGGMMALLYLDMDRFKAVNDIHGHAAGDLLLQAFAKRVLGCV
RKQDAVARLGGDEFAVILESVGHAAAARSVATDILCAVGQRFHFEGMFADIDVSIGVALYDGGPMQERELMRLADVLLYR
AKGAGRGRYEIGPPELITADSAQ

Sequences:

>Translated_663_residues
MPVFLPSLKARIALITTVLAAVFGTGIVLTSLFAAHRDLQDVLQDEQDSIVKLSADQLDTAMEDRIMLLRQQAAQLGGLF
GTARGAQAPAAMAQALAQVRRAIPVPGAFNSLMVVDARGTALGDSGMVTEVGDRTYFREAARTLAPVISPPIRARTNDRL
GVIVAVPVLSAQGRFAGLVGGWLDLARSNFLVEVLHNRLGTTGFYCLVSAGSRPVYIQHPDPTQARQPARAIGDTCGQDD
RAATLEFLTPTRPVVSRYLMSTTGWELVALLPAHEAYAPLHRMQQRFLILAGLALLLVAASIWLAVRLLLAPLTRLHEVV
RDSASDLSAFERLPERQHRDEIGDLARAFTRLMRDVRERRQELDRSERRLRAVTDTLPSLLAFIDTDERYVFNNIAYEHT
FGLTLEELRGKTVREVLGETRYARAQPFLQRALAGAVVTFESEENEPEYHCMETSYRPEWSADGSEVVGVHIHVQDITPR
KLETMRLSHISSTDHLTQLLNRSAFESRLQDAMARCRESGGMMALLYLDMDRFKAVNDIHGHAAGDLLLQAFAKRVLGCV
RKQDAVARLGGDEFAVILESVGHAAAARSVATDILCAVGQRFHFEGMFADIDVSIGVALYDGGPMQERELMRLADVLLYR
AKGAGRGRYEIGPPELITADSAQ
>Mature_662_residues
PVFLPSLKARIALITTVLAAVFGTGIVLTSLFAAHRDLQDVLQDEQDSIVKLSADQLDTAMEDRIMLLRQQAAQLGGLFG
TARGAQAPAAMAQALAQVRRAIPVPGAFNSLMVVDARGTALGDSGMVTEVGDRTYFREAARTLAPVISPPIRARTNDRLG
VIVAVPVLSAQGRFAGLVGGWLDLARSNFLVEVLHNRLGTTGFYCLVSAGSRPVYIQHPDPTQARQPARAIGDTCGQDDR
AATLEFLTPTRPVVSRYLMSTTGWELVALLPAHEAYAPLHRMQQRFLILAGLALLLVAASIWLAVRLLLAPLTRLHEVVR
DSASDLSAFERLPERQHRDEIGDLARAFTRLMRDVRERRQELDRSERRLRAVTDTLPSLLAFIDTDERYVFNNIAYEHTF
GLTLEELRGKTVREVLGETRYARAQPFLQRALAGAVVTFESEENEPEYHCMETSYRPEWSADGSEVVGVHIHVQDITPRK
LETMRLSHISSTDHLTQLLNRSAFESRLQDAMARCRESGGMMALLYLDMDRFKAVNDIHGHAAGDLLLQAFAKRVLGCVR
KQDAVARLGGDEFAVILESVGHAAAARSVATDILCAVGQRFHFEGMFADIDVSIGVALYDGGPMQERELMRLADVLLYRA
KGAGRGRYEIGPPELITADSAQ

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=317, Percent_Identity=33.1230283911672, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1786584, Length=175, Percent_Identity=34.2857142857143, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1787541, Length=268, Percent_Identity=28.3582089552239, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI87081881, Length=175, Percent_Identity=37.1428571428571, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI145693134, Length=176, Percent_Identity=32.3863636363636, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87082007, Length=161, Percent_Identity=35.4037267080745, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787262, Length=169, Percent_Identity=29.585798816568, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787802, Length=160, Percent_Identity=35, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788956, Length=156, Percent_Identity=37.8205128205128, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1787056, Length=170, Percent_Identity=34.1176470588235, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI87081974, Length=86, Percent_Identity=37.2093023255814, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI87081977, Length=219, Percent_Identity=26.4840182648402, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF05231 MASE1; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 72993; Mature: 72862

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVFLPSLKARIALITTVLAAVFGTGIVLTSLFAAHRDLQDVLQDEQDSIVKLSADQLDT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHH
AMEDRIMLLRQQAAQLGGLFGTARGAQAPAAMAQALAQVRRAIPVPGAFNSLMVVDARGT
HHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCC
ALGDSGMVTEVGDRTYFREAARTLAPVISPPIRARTNDRLGVIVAVPVLSAQGRFAGLVG
CCCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHH
GWLDLARSNFLVEVLHNRLGTTGFYCLVSAGSRPVYIQHPDPTQARQPARAIGDTCGQDD
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCCCCCCCHHHHHHCCCCCC
RAATLEFLTPTRPVVSRYLMSTTGWELVALLPAHEAYAPLHRMQQRFLILAGLALLLVAA
CCCCHHHCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIWLAVRLLLAPLTRLHEVVRDSASDLSAFERLPERQHRDEIGDLARAFTRLMRDVRERR
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QELDRSERRLRAVTDTLPSLLAFIDTDERYVFNNIAYEHTFGLTLEELRGKTVREVLGET
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHCCCCCHHHHCCHHHHHHHCCH
RYARAQPFLQRALAGAVVTFESEENEPEYHCMETSYRPEWSADGSEVVGVHIHVQDITPR
HHHHHHHHHHHHHHHHEEEECCCCCCCCEEEECCCCCCCCCCCCCEEEEEEEEEECCCCH
KLETMRLSHISSTDHLTQLLNRSAFESRLQDAMARCRESGGMMALLYLDMDRFKAVNDIH
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHC
GHAAGDLLLQAFAKRVLGCVRKQDAVARLGGDEFAVILESVGHAAAARSVATDILCAVGQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RFHFEGMFADIDVSIGVALYDGGPMQERELMRLADVLLYRAKGAGRGRYEIGPPELITAD
HHEECCEEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCC
SAQ
CCC
>Mature Secondary Structure 
PVFLPSLKARIALITTVLAAVFGTGIVLTSLFAAHRDLQDVLQDEQDSIVKLSADQLDT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHH
AMEDRIMLLRQQAAQLGGLFGTARGAQAPAAMAQALAQVRRAIPVPGAFNSLMVVDARGT
HHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCC
ALGDSGMVTEVGDRTYFREAARTLAPVISPPIRARTNDRLGVIVAVPVLSAQGRFAGLVG
CCCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHH
GWLDLARSNFLVEVLHNRLGTTGFYCLVSAGSRPVYIQHPDPTQARQPARAIGDTCGQDD
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCCCCCCCHHHHHHCCCCCC
RAATLEFLTPTRPVVSRYLMSTTGWELVALLPAHEAYAPLHRMQQRFLILAGLALLLVAA
CCCCHHHCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIWLAVRLLLAPLTRLHEVVRDSASDLSAFERLPERQHRDEIGDLARAFTRLMRDVRERR
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QELDRSERRLRAVTDTLPSLLAFIDTDERYVFNNIAYEHTFGLTLEELRGKTVREVLGET
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHCCCCCHHHHCCHHHHHHHCCH
RYARAQPFLQRALAGAVVTFESEENEPEYHCMETSYRPEWSADGSEVVGVHIHVQDITPR
HHHHHHHHHHHHHHHHEEEECCCCCCCCEEEECCCCCCCCCCCCCEEEEEEEEEECCCCH
KLETMRLSHISSTDHLTQLLNRSAFESRLQDAMARCRESGGMMALLYLDMDRFKAVNDIH
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHC
GHAAGDLLLQAFAKRVLGCVRKQDAVARLGGDEFAVILESVGHAAAARSVATDILCAVGQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RFHFEGMFADIDVSIGVALYDGGPMQERELMRLADVLLYRAKGAGRGRYEIGPPELITAD
HHEECCEEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCC
SAQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7984428 [H]