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The map label for this gene is yyaJ [H]

Identifier: 73539292

GI number: 73539292

Start: 2261043

End: 2262428

Strand: Reverse

Name: yyaJ [H]

Synonym: Reut_B5470

Alternate gene names: 73539292

Gene position: 2262428-2261043 (Counterclockwise)

Preceding gene: 73539293

Following gene: 73539290

Centisome position: 82.99

GC content: 62.84

Gene sequence:

>1386_bases
ATGAGCGATCTATCGCCAAGCGTGGCGGACGCGGTGCGCAATGCGCCGTCGCACCGCACAGTTCCAGCTACACACACAAC
GGACTCCATTGCCGTCGGCAAGCTGTTCGAACAATTTCCACTGACCCGCGAACACCTGAAGAGTTGCCTCGCGCTGTTCA
TGGTCTTTGCCATCGAGGCGTGGGAGATGATGATCATCGTCTACACCGCGCAGCTGATCGGCAAGGAGTTCCAGCTCGAC
GCCGCGGCGCTTGGCAACCTGATCGGCGCGATCTTTGTCGGCATGCTGATCGGCTCGCTGTGGTGGGGCAAGATCTCGGA
TCGGATTGGCCGCAAGCGCGCCATCATTCTGAGCCTCGTGCTCTACGGGCTGATTTCCGTTGCCAGCGCCATGGCCACGA
GCTACGGCATGCTGTACGCGCTGCGCCTGCTCTCAGGCATCGCGGCCGTCGGCATGATGGTGGTGACGTTTGCCCATTTC
GAGGAACTACTGCCGGTGAAGGTACGGGGTACCTGTACCGTGTACCTGGCATCGGGCTGGCCCGTCGGGATGCTGATGGC
GCTGGGCGTATCGATGTGGCTGCTGCCGTGGGGCTGGCGCGGCATCATCGCGGTGAGTTCGCTTGCAGCGGTATGGGCGT
TCGTCGTGGCGCGGTGGGTGGAGGAATCGCCGTACTGGCTGGCCGCGGTTGGCCGCGACGACGAGGCAAAGGCCGTGATC
GGCAGGCTGAGCCGCGGCGCCGTGATCGTGCCGCCCTCGACGCGGCTGCACGTGGAAAAAGGCGCTCACGGTGGCACGCA
CCGCGAGTTGTTCTCCGGGTCGGCGCTGCGCATCACGCTGCTGCAAATCGCAGTCAACTTCACGTTCTCGTGGGGCTACT
GGGGCCTGCAGACCTGGCTGCCAACGCTGTTGCAGCAGCGCGGCCTGAACCTGCCGCAGAGCTACGGCTTCATCGCGATC
TCGGCAATCTGCATGATCCCCGGCTACATTGCAGCGTCCTTCCTGACCGGAAAATTCGGCCGCAAGCGCGTGATTGTCGG
CTTCGTCGGCATGTCCGTGATTGCCGGCTACGTGTTCGCGAATGCGCAAACCATGGAAATGCTGTACGCGGGCAACTTCG
CGCTGGCCTTCTTCAGCATGGGCGCGTGGGGCGTGTGGGATACGTGGATCGGTGAACTGTATTCCACTCGGTTGCGCACG
CTCGGCTACAGCTGGGCGGTGTTCGCGCAGCGCGTCGCCAATATTGCGGCACCCAGCCTGATCGGCATGCTGCTGGTCCG
TGGATGGTCCTTCAACACGACGACGACGATGATCAACGCATTCATGCTGGCGACGGTGCTGCTGGCGCTGTTCATGCCTG
AAACTGAGGGCAAGGAATTGGACTAG

Upstream 100 bases:

>100_bases
GCCAATTGCCGGGGCGTTCTGGCTGTTCAAGGGACCGGTGCCGGTCGCCCATGTCGTGCGAGCCTGATCCCACAAGCAAA
GAGAAAGAGGAGACATCCCC

Downstream 100 bases:

>100_bases
CGTTGCCAGCGCAGCGGCCGCCGGCAGATAGTTGGCGCGCCGCTGTCGGCAGTCATCATCGCGCTGCGTCCTTCAGGAAA
AGGGATGGAGCTTCGGCTGC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MSDLSPSVADAVRNAPSHRTVPATHTTDSIAVGKLFEQFPLTREHLKSCLALFMVFAIEAWEMMIIVYTAQLIGKEFQLD
AAALGNLIGAIFVGMLIGSLWWGKISDRIGRKRAIILSLVLYGLISVASAMATSYGMLYALRLLSGIAAVGMMVVTFAHF
EELLPVKVRGTCTVYLASGWPVGMLMALGVSMWLLPWGWRGIIAVSSLAAVWAFVVARWVEESPYWLAAVGRDDEAKAVI
GRLSRGAVIVPPSTRLHVEKGAHGGTHRELFSGSALRITLLQIAVNFTFSWGYWGLQTWLPTLLQQRGLNLPQSYGFIAI
SAICMIPGYIAASFLTGKFGRKRVIVGFVGMSVIAGYVFANAQTMEMLYAGNFALAFFSMGAWGVWDTWIGELYSTRLRT
LGYSWAVFAQRVANIAAPSLIGMLLVRGWSFNTTTTMINAFMLATVLLALFMPETEGKELD

Sequences:

>Translated_461_residues
MSDLSPSVADAVRNAPSHRTVPATHTTDSIAVGKLFEQFPLTREHLKSCLALFMVFAIEAWEMMIIVYTAQLIGKEFQLD
AAALGNLIGAIFVGMLIGSLWWGKISDRIGRKRAIILSLVLYGLISVASAMATSYGMLYALRLLSGIAAVGMMVVTFAHF
EELLPVKVRGTCTVYLASGWPVGMLMALGVSMWLLPWGWRGIIAVSSLAAVWAFVVARWVEESPYWLAAVGRDDEAKAVI
GRLSRGAVIVPPSTRLHVEKGAHGGTHRELFSGSALRITLLQIAVNFTFSWGYWGLQTWLPTLLQQRGLNLPQSYGFIAI
SAICMIPGYIAASFLTGKFGRKRVIVGFVGMSVIAGYVFANAQTMEMLYAGNFALAFFSMGAWGVWDTWIGELYSTRLRT
LGYSWAVFAQRVANIAAPSLIGMLLVRGWSFNTTTTMINAFMLATVLLALFMPETEGKELD
>Mature_460_residues
SDLSPSVADAVRNAPSHRTVPATHTTDSIAVGKLFEQFPLTREHLKSCLALFMVFAIEAWEMMIIVYTAQLIGKEFQLDA
AALGNLIGAIFVGMLIGSLWWGKISDRIGRKRAIILSLVLYGLISVASAMATSYGMLYALRLLSGIAAVGMMVVTFAHFE
ELLPVKVRGTCTVYLASGWPVGMLMALGVSMWLLPWGWRGIIAVSSLAAVWAFVVARWVEESPYWLAAVGRDDEAKAVIG
RLSRGAVIVPPSTRLHVEKGAHGGTHRELFSGSALRITLLQIAVNFTFSWGYWGLQTWLPTLLQQRGLNLPQSYGFIAIS
AICMIPGYIAASFLTGKFGRKRVIVGFVGMSVIAGYVFANAQTMEMLYAGNFALAFFSMGAWGVWDTWIGELYSTRLRTL
GYSWAVFAQRVANIAAPSLIGMLLVRGWSFNTTTTMINAFMLATVLLALFMPETEGKELD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24308167, Length=463, Percent_Identity=24.8380129589633, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI4507005, Length=426, Percent_Identity=24.8826291079812, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI73695465, Length=263, Percent_Identity=24.3346007604563, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI166064021, Length=403, Percent_Identity=25.5583126550869, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI216548223, Length=280, Percent_Identity=24.2857142857143, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI31542327, Length=401, Percent_Identity=26.4339152119701, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI7662270, Length=354, Percent_Identity=22.5988700564972, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI166197673, Length=361, Percent_Identity=26.3157894736842, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI262399383, Length=263, Percent_Identity=24.3346007604563, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI213021148, Length=284, Percent_Identity=25, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI24497490, Length=429, Percent_Identity=22.8438228438228, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI24497476, Length=364, Percent_Identity=25, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI20070188, Length=358, Percent_Identity=24.3016759776536, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI24497497, Length=343, Percent_Identity=24.4897959183673, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI90669191, Length=343, Percent_Identity=24.4897959183673, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1788074, Length=344, Percent_Identity=27.0348837209302, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1788068, Length=456, Percent_Identity=25, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1786229, Length=410, Percent_Identity=23.1707317073171, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI87082159, Length=282, Percent_Identity=28.3687943262411, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082404, Length=379, Percent_Identity=21.8997361477573, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082231, Length=207, Percent_Identity=24.6376811594203, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87081723, Length=385, Percent_Identity=24.9350649350649, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1789207, Length=156, Percent_Identity=32.6923076923077, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32564663, Length=428, Percent_Identity=23.3644859813084, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI71980822, Length=392, Percent_Identity=23.2142857142857, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI25145172, Length=422, Percent_Identity=23.4597156398104, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI32565921, Length=396, Percent_Identity=27.020202020202, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17554160, Length=199, Percent_Identity=28.1407035175879, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24640198, Length=476, Percent_Identity=24.7899159663866, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24640196, Length=476, Percent_Identity=24.7899159663866, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24640200, Length=476, Percent_Identity=24.7899159663866, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI19922874, Length=445, Percent_Identity=23.1460674157303, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI19922616, Length=391, Percent_Identity=24.2966751918159, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24649618, Length=348, Percent_Identity=25.5747126436782, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24649622, Length=402, Percent_Identity=23.134328358209, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 50424; Mature: 50293

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLSPSVADAVRNAPSHRTVPATHTTDSIAVGKLFEQFPLTREHLKSCLALFMVFAIEA
CCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
WEMMIIVYTAQLIGKEFQLDAAALGNLIGAIFVGMLIGSLWWGKISDRIGRKRAIILSLV
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
LYGLISVASAMATSYGMLYALRLLSGIAAVGMMVVTFAHFEELLPVKVRGTCTVYLASGW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCEEEEEEECCC
PVGMLMALGVSMWLLPWGWRGIIAVSSLAAVWAFVVARWVEESPYWLAAVGRDDEAKAVI
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHH
GRLSRGAVIVPPSTRLHVEKGAHGGTHRELFSGSALRITLLQIAVNFTFSWGYWGLQTWL
HHCCCCEEEECCCCEEEEECCCCCCCHHHHHCCCHHHHHHEEHHHHHEEECCHHHHHHHH
PTLLQQRGLNLPQSYGFIAISAICMIPGYIAASFLTGKFGRKRVIVGFVGMSVIAGYVFA
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHC
NAQTMEMLYAGNFALAFFSMGAWGVWDTWIGELYSTRLRTLGYSWAVFAQRVANIAAPSL
CHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
IGMLLVRGWSFNTTTTMINAFMLATVLLALFMPETEGKELD
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SDLSPSVADAVRNAPSHRTVPATHTTDSIAVGKLFEQFPLTREHLKSCLALFMVFAIEA
CCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
WEMMIIVYTAQLIGKEFQLDAAALGNLIGAIFVGMLIGSLWWGKISDRIGRKRAIILSLV
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
LYGLISVASAMATSYGMLYALRLLSGIAAVGMMVVTFAHFEELLPVKVRGTCTVYLASGW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCEEEEEEECCC
PVGMLMALGVSMWLLPWGWRGIIAVSSLAAVWAFVVARWVEESPYWLAAVGRDDEAKAVI
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHH
GRLSRGAVIVPPSTRLHVEKGAHGGTHRELFSGSALRITLLQIAVNFTFSWGYWGLQTWL
HHCCCCEEEECCCCEEEEECCCCCCCHHHHHCCCHHHHHHEEHHHHHEEECCHHHHHHHH
PTLLQQRGLNLPQSYGFIAISAICMIPGYIAASFLTGKFGRKRVIVGFVGMSVIAGYVFA
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHC
NAQTMEMLYAGNFALAFFSMGAWGVWDTWIGELYSTRLRTLGYSWAVFAQRVANIAAPSL
CHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
IGMLLVRGWSFNTTTTMINAFMLATVLLALFMPETEGKELD
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]