BacMap

Definition	Ralstonia eutropha JMP134 chromosome chromosome 2, complete sequence.
Accession	NC_007348
Length	2,726,152

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The map label for this gene is bacC [H]

Identifier: 73539286

GI number: 73539286

Start: 2255013

End: 2255774

Strand: Direct

Name: bacC [H]

Synonym: Reut_B5464

Alternate gene names: 73539286

Gene position: 2255013-2255774 (Clockwise)

Preceding gene: 73539285

Following gene: 73539287

Centisome position: 82.72

GC content: 62.73

Gene sequence:

>762_bases
ATGGAGTACATCGACATGAAGCTCAAGGACAAGGTCGCCATCGTAACGGGCGGTGCCAGCGGTATTGGCGAGGCAACGGT
TCGGCTGTTCGCTTCCCAAGGTGCCAGCGTCGTCATTGCCGACCGCTCGGCACTCGGCGAGAAGCTCGCGCGTGAACTGA
GCGAAAGCAGCTTGGCCGCGCACTACAGCGAAGTCGATGTGTCGCGCGAGGACGACACGCGCAGGCTCATCGATGACACC
GTGAGCCGCTTCGGGCGGCTCGACATCATGGTCGCCAATGCCGGCATTGCGCATCCGTCTGCACCAGTCGAGGATGTCAG
TGTCGAGCAATGGCAGCAGATGATCGACGTCAACCTGACCGGCGTCTTCCTGAGCAACAAGCTTGCCATTGTGCAGATGA
AGAAGCAGGGCACCGGCGGCGCGATCGTCAACATGGCATCGATACTCGGGCATGTCGGGATGCCGGGCGCGGCGTCCTAC
AACGCGGCAAAGGGCGGCGTGGTCAACCTCACGCGCTCTCTCGGCGTCTCGCATGCACAGGACGGCATACGCGTCAACGC
GGTATGTCCGGGTTTCGTGGCAACACCGCTGATCGAACGTGCCACTGAGGAAGCCCGTGCGCGCCTGGTGGCGGCGCATC
CGATTGGCCGCCTGGGTCACGCCGATGAGGTCGCGAAGGCCGTGCTGTTTCTCGCGAGCGACGATGCATCGTTCATCGTC
GGTACGAGCCTGATGGTCGATGGAGGGTATTGCGCGCAATGA

Upstream 100 bases:

>100_bases
CGCTCTGTTCCTCGCTTCGGACGAGTCGTCCTACATGAACGGCGCGGAGTTGGTGCTGGACGGCGGATTCACGGCGGCCT
AGTCGGCAACCACAGACTGA

Downstream 100 bases:

>100_bases
GAAGCCTATCGATGAAGACCTTGCGTACGACGGCAATTTCGAGTGCGGCACTGATCGTGCTTGGGGCCTGTACGGCGTCC
TCCGTGCCGCAAGGCAATGC

Product: NAD-dependent epimerase/dehydratase

Products: D-glucono-1,5-lactone; NADH; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MEYIDMKLKDKVAIVTGGASGIGEATVRLFASQGASVVIADRSALGEKLARELSESSLAAHYSEVDVSREDDTRRLIDDT
VSRFGRLDIMVANAGIAHPSAPVEDVSVEQWQQMIDVNLTGVFLSNKLAIVQMKKQGTGGAIVNMASILGHVGMPGAASY
NAAKGGVVNLTRSLGVSHAQDGIRVNAVCPGFVATPLIERATEEARARLVAAHPIGRLGHADEVAKAVLFLASDDASFIV
GTSLMVDGGYCAQ

Sequences:

>Translated_253_residues
MEYIDMKLKDKVAIVTGGASGIGEATVRLFASQGASVVIADRSALGEKLARELSESSLAAHYSEVDVSREDDTRRLIDDT
VSRFGRLDIMVANAGIAHPSAPVEDVSVEQWQQMIDVNLTGVFLSNKLAIVQMKKQGTGGAIVNMASILGHVGMPGAASY
NAAKGGVVNLTRSLGVSHAQDGIRVNAVCPGFVATPLIERATEEARARLVAAHPIGRLGHADEVAKAVLFLASDDASFIV
GTSLMVDGGYCAQ
>Mature_253_residues
MEYIDMKLKDKVAIVTGGASGIGEATVRLFASQGASVVIADRSALGEKLARELSESSLAAHYSEVDVSREDDTRRLIDDT
VSRFGRLDIMVANAGIAHPSAPVEDVSVEQWQQMIDVNLTGVFLSNKLAIVQMKKQGTGGAIVNMASILGHVGMPGAASY
NAAKGGVVNLTRSLGVSHAQDGIRVNAVCPGFVATPLIERATEEARARLVAAHPIGRLGHADEVAKAVLFLASDDASFIV
GTSLMVDGGYCAQ

Specific function: Part of the bacABCDE operon responsible for the biosynthesis of bacilysin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI59889578, Length=229, Percent_Identity=37.117903930131, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI15277342, Length=253, Percent_Identity=35.1778656126482, Blast_Score=135, Evalue=3e-32,
Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=34.5238095238095, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=32.6612903225806, Blast_Score=125, Evalue=3e-29,
Organism=Homo sapiens, GI40254992, Length=241, Percent_Identity=36.9294605809129, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI4758504, Length=253, Percent_Identity=33.9920948616601, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI66933014, Length=251, Percent_Identity=33.0677290836653, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI10190704, Length=250, Percent_Identity=32.4, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI31542939, Length=212, Percent_Identity=33.0188679245283, Blast_Score=107, Evalue=7e-24,
Organism=Homo sapiens, GI5031737, Length=257, Percent_Identity=29.5719844357977, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI126723750, Length=251, Percent_Identity=28.2868525896414, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI83715985, Length=254, Percent_Identity=32.6771653543307, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI109715829, Length=243, Percent_Identity=28.3950617283951, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI7705925, Length=252, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=31.3186813186813, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI224922801, Length=179, Percent_Identity=32.4022346368715, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI4503301, Length=251, Percent_Identity=29.0836653386454, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI33667109, Length=202, Percent_Identity=30.1980198019802, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI210032110, Length=190, Percent_Identity=30.5263157894737, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4504505, Length=196, Percent_Identity=30.6122448979592, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI142976729, Length=232, Percent_Identity=26.2931034482759, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI7706318, Length=212, Percent_Identity=29.2452830188679, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI20149619, Length=202, Percent_Identity=29.2079207920792, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI40807363, Length=211, Percent_Identity=27.0142180094787, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI150247226, Length=192, Percent_Identity=29.6875, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1788459, Length=242, Percent_Identity=33.8842975206612, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=36.8421052631579, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=36.9047619047619, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=34.4262295081967, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI87082160, Length=248, Percent_Identity=32.258064516129, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1789208, Length=260, Percent_Identity=32.3076923076923, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1787905, Length=247, Percent_Identity=31.1740890688259, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1786812, Length=256, Percent_Identity=33.984375, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=29.9595141700405, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=31.6, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=28.8461538461538, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI2367365, Length=246, Percent_Identity=30.0813008130081, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787820, Length=226, Percent_Identity=26.5486725663717, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1787526, Length=243, Percent_Identity=23.4567901234568, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=243, Percent_Identity=39.5061728395062, Blast_Score=154, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI25147288, Length=244, Percent_Identity=37.2950819672131, Blast_Score=150, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI71994600, Length=250, Percent_Identity=35.2, Blast_Score=137, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17561402, Length=259, Percent_Identity=34.7490347490347, Blast_Score=135, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=34.2741935483871, Blast_Score=130, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=32.4, Blast_Score=129, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=34.0909090909091, Blast_Score=121, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17562904, Length=271, Percent_Identity=33.210332103321, Blast_Score=118, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=32.4528301886792, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17560220, Length=266, Percent_Identity=33.8345864661654, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=29.9625468164794, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17562910, Length=269, Percent_Identity=31.9702602230483, Blast_Score=111, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17551412, Length=265, Percent_Identity=32.8301886792453, Blast_Score=110, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17538182, Length=252, Percent_Identity=31.3492063492063, Blast_Score=110, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17562990, Length=262, Percent_Identity=31.6793893129771, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI193204405, Length=271, Percent_Identity=32.8413284132841, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=31.6981132075472, Blast_Score=104, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17560150, Length=266, Percent_Identity=31.5789473684211, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17538480, Length=267, Percent_Identity=32.5842696629214, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=31.9391634980989, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17565030, Length=263, Percent_Identity=33.4600760456274, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=32.3308270676692, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=32.6996197718631, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=31.1787072243346, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI72000259, Length=266, Percent_Identity=28.1954887218045, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17536651, Length=253, Percent_Identity=28.4584980237154, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17536025, Length=256, Percent_Identity=31.640625, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI115534694, Length=252, Percent_Identity=29.3650793650794, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17561272, Length=250, Percent_Identity=30.8, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17564282, Length=239, Percent_Identity=27.6150627615063, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193203117, Length=243, Percent_Identity=27.5720164609054, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=196, Percent_Identity=27.5510204081633, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=239, Percent_Identity=27.1966527196653, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=248, Percent_Identity=27.8225806451613, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17568967, Length=199, Percent_Identity=27.6381909547739, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17567345, Length=193, Percent_Identity=28.4974093264249, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=249, Percent_Identity=27.710843373494, Blast_Score=96, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6322861, Length=198, Percent_Identity=29.2929292929293, Blast_Score=89, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6323882, Length=247, Percent_Identity=28.3400809716599, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6320089, Length=198, Percent_Identity=26.7676767676768, Blast_Score=66, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6322226, Length=190, Percent_Identity=26.8421052631579, Blast_Score=66, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=38.0952380952381, Blast_Score=150, Evalue=8e-37,
Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=36.7588932806324, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=36.4, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=36.3636363636364, Blast_Score=141, Evalue=4e-34,
Organism=Drosophila melanogaster, GI21355319, Length=259, Percent_Identity=33.5907335907336, Blast_Score=131, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=34.136546184739, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI17737361, Length=253, Percent_Identity=33.596837944664, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24643142, Length=245, Percent_Identity=30.6122448979592, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24644337, Length=249, Percent_Identity=32.9317269076305, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24641232, Length=237, Percent_Identity=29.1139240506329, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI221331218, Length=204, Percent_Identity=31.8627450980392, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24665243, Length=204, Percent_Identity=31.8627450980392, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI18859837, Length=192, Percent_Identity=30.7291666666667, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI221331216, Length=205, Percent_Identity=32.1951219512195, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24665247, Length=205, Percent_Identity=32.1951219512195, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI281364494, Length=202, Percent_Identity=30.1980198019802, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24665264, Length=200, Percent_Identity=32, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI28571387, Length=237, Percent_Identity=27.4261603375527, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24663911, Length=234, Percent_Identity=28.6324786324786, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI116007236, Length=242, Percent_Identity=27.6859504132231, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281364892, Length=195, Percent_Identity=29.7435897435897, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21358495, Length=196, Percent_Identity=26.530612244898, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24649181, Length=191, Percent_Identity=29.3193717277487, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21357673, Length=201, Percent_Identity=27.8606965174129, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI116007238, Length=174, Percent_Identity=31.0344827586207, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.47

Molecular weight: Translated: 26489; Mature: 26489

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYIDMKLKDKVAIVTGGASGIGEATVRLFASQGASVVIADRSALGEKLARELSESSLAA
CCEECCEECCEEEEEECCCCCCCHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHH
HYSEVDVSREDDTRRLIDDTVSRFGRLDIMVANAGIAHPSAPVEDVSVEQWQQMIDVNLT
HHHHCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCEE
GVFLSNKLAIVQMKKQGTGGAIVNMASILGHVGMPGAASYNAAKGGVVNLTRSLGVSHAQ
EEEECCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHCCCCCC
DGIRVNAVCPGFVATPLIERATEEARARLVAAHPIGRLGHADEVAKAVLFLASDDASFIV
CCEEEEEECCCHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHEEEEECCCCCEEE
GTSLMVDGGYCAQ
EEEEEECCCCCCC
>Mature Secondary Structure
MEYIDMKLKDKVAIVTGGASGIGEATVRLFASQGASVVIADRSALGEKLARELSESSLAA
CCEECCEECCEEEEEECCCCCCCHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHH
HYSEVDVSREDDTRRLIDDTVSRFGRLDIMVANAGIAHPSAPVEDVSVEQWQQMIDVNLT
HHHHCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCEE
GVFLSNKLAIVQMKKQGTGGAIVNMASILGHVGMPGAASYNAAKGGVVNLTRSLGVSHAQ
EEEECCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHCCCCCC
DGIRVNAVCPGFVATPLIERATEEARARLVAAHPIGRLGHADEVAKAVLFLASDDASFIV
CCEEEEEECCCHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHEEEEECCCCCEEE
GTSLMVDGGYCAQ
EEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: beta-D-glucose; NAD+; NADP+

Specific reaction: beta-D-glucose + NAD(P)+ = D-glucono-1,5-lactone + NAD(P)H + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA