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The map label for this gene is nreC [H]

Identifier: 73539273

GI number: 73539273

Start: 2243068

End: 2243739

Strand: Reverse

Name: nreC [H]

Synonym: Reut_B5451

Alternate gene names: 73539273

Gene position: 2243739-2243068 (Counterclockwise)

Preceding gene: 73539274

Following gene: 73539272

Centisome position: 82.3

GC content: 58.63

Gene sequence:

>672_bases
ATGCCAGGGAAATCATGTAGCAGCAGCCCGGGCCGCCCGGCCAGGGTCCTGATCGTGGATGACCACCCCATCGTCCGCGA
GGGCCTGGCCCACCTGCTGAATATGCACGAGGAACTTCAGGTTTGTTGTACGGCCAGCAGTGCTGAAGAAGCGTTGCAGG
AGATGGTCTGCGAGCCTGACATGGCAATCGTGGATCTCAGCCTGCATAAGGACTCAGGCCTGGATCTTGTCAGAACACTT
CGGCAACACCACCCGGAACTCGCGATCCTTGTCCTCAGCATGCATGACGAATCCTTGTTTGCCGAACGCGCACTGCGGGC
CGGAGCAAACGGATATCTGATGAAGCTCGAGGCCACGGAACATATCATGAGCGCCATCCAGGAGGTACTCGCAGGGAATA
TCTATCTGAGCGCGGCCATGCATGGCAGACTCGCCCGGGCCCTGACGGCTTCCAGGAACGTCACGGCCGGTTCGGTGGCG
AGCCTCTCCGAACGGGAATTCGAGGTCCTCCACCTGATCGGACTCGGTTTTGGCACCCGCGAGATCGCGAGGAAACTGAA
CCGGAGTATCAAGACCGTCGAGGCGCACCAGGCGAACATCAAAGAGAAGCTGGACATTCATAGCGGAAAGGCGTTGATCC
GTTTCGCTATTCAGTGGATCGAGAACCAGTAG

Upstream 100 bases:

>100_bases
CACCGTGCGAGCCTGCTCGGTGGTGCATGCGCGGTGACCCGCAACGCCACGGGCGGAACCACGGTTATCATCAGCTATCC
AGTCGCGCAAGGTCCCGGCC

Downstream 100 bases:

>100_bases
GCGGTCAGCCCGATGGCCGCTGTCACAATGGCGTCTTGCCGGACGGGCTTCCGGCGCGAAGTTCCCGAACTTGCCGAGGA
CGTGGCAGCCTTTGCCGACG

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MPGKSCSSSPGRPARVLIVDDHPIVREGLAHLLNMHEELQVCCTASSAEEALQEMVCEPDMAIVDLSLHKDSGLDLVRTL
RQHHPELAILVLSMHDESLFAERALRAGANGYLMKLEATEHIMSAIQEVLAGNIYLSAAMHGRLARALTASRNVTAGSVA
SLSEREFEVLHLIGLGFGTREIARKLNRSIKTVEAHQANIKEKLDIHSGKALIRFAIQWIENQ

Sequences:

>Translated_223_residues
MPGKSCSSSPGRPARVLIVDDHPIVREGLAHLLNMHEELQVCCTASSAEEALQEMVCEPDMAIVDLSLHKDSGLDLVRTL
RQHHPELAILVLSMHDESLFAERALRAGANGYLMKLEATEHIMSAIQEVLAGNIYLSAAMHGRLARALTASRNVTAGSVA
SLSEREFEVLHLIGLGFGTREIARKLNRSIKTVEAHQANIKEKLDIHSGKALIRFAIQWIENQ
>Mature_222_residues
PGKSCSSSPGRPARVLIVDDHPIVREGLAHLLNMHEELQVCCTASSAEEALQEMVCEPDMAIVDLSLHKDSGLDLVRTLR
QHHPELAILVLSMHDESLFAERALRAGANGYLMKLEATEHIMSAIQEVLAGNIYLSAAMHGRLARALTASRNVTAGSVAS
LSEREFEVLHLIGLGFGTREIARKLNRSIKTVEAHQANIKEKLDIHSGKALIRFAIQWIENQ

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786747, Length=206, Percent_Identity=32.5242718446602, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788222, Length=206, Percent_Identity=32.0388349514563, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1790102, Length=205, Percent_Identity=34.6341463414634, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1787473, Length=189, Percent_Identity=32.8042328042328, Blast_Score=91, Evalue=4e-20,
Organism=Escherichia coli, GI1788521, Length=198, Percent_Identity=31.3131313131313, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1788712, Length=201, Percent_Identity=27.363184079602, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI1788546, Length=207, Percent_Identity=28.5024154589372, Blast_Score=81, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24510; Mature: 24378

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGKSCSSSPGRPARVLIVDDHPIVREGLAHLLNMHEELQVCCTASSAEEALQEMVCEPD
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
MAIVDLSLHKDSGLDLVRTLRQHHPELAILVLSMHDESLFAERALRAGANGYLMKLEATE
CEEEEEEECCCCCHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCCCEEEEEHHHH
HIMSAIQEVLAGNIYLSAAMHGRLARALTASRNVTAGSVASLSEREFEVLHLIGLGFGTR
HHHHHHHHHHHCCHHEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHH
EIARKLNRSIKTVEAHQANIKEKLDIHSGKALIRFAIQWIENQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
PGKSCSSSPGRPARVLIVDDHPIVREGLAHLLNMHEELQVCCTASSAEEALQEMVCEPD
CCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
MAIVDLSLHKDSGLDLVRTLRQHHPELAILVLSMHDESLFAERALRAGANGYLMKLEATE
CEEEEEEECCCCCHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCCCEEEEEHHHH
HIMSAIQEVLAGNIYLSAAMHGRLARALTASRNVTAGSVASLSEREFEVLHLIGLGFGTR
HHHHHHHHHHHCCHHEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHH
EIARKLNRSIKTVEAHQANIKEKLDIHSGKALIRFAIQWIENQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]