| Definition | Ralstonia eutropha JMP134 chromosome chromosome 2, complete sequence. |
|---|---|
| Accession | NC_007348 |
| Length | 2,726,152 |
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The map label for this gene is kduD [H]
Identifier: 73539266
GI number: 73539266
Start: 2235199
End: 2235969
Strand: Reverse
Name: kduD [H]
Synonym: Reut_B5444
Alternate gene names: 73539266
Gene position: 2235969-2235199 (Counterclockwise)
Preceding gene: 73539267
Following gene: 73539264
Centisome position: 82.02
GC content: 63.29
Gene sequence:
>771_bases ATGCCTTTCACCCCCTTCGACCTTACCGGCAAAGTGGCGCTGATTACCGGCGGCAACGGCGGCATCGGCCTTGGCATGGC CGAAGGCCTGGCCCAGGCCGGCGCCGATATCGCGATCTGGGGCACCAATACGCAGAAAAACGCAGCCGCCGCCGAGCGGC TCGCGCAATATGGGCGCAAGGTGCATACCGCGATCTGCGATGTGAGCAACGAGTCTTCCGTGGCTGCGGCCATGGATGGG ACGCTTGCGGCGCTGGGTCGCCTGGATGGCTGCTTCGCCAATGCCGGTGTCTCGGCGCGTGGTACGCGCTTCGAAGAAAT GGGTACGGACGATTGGCATCGGGTGATGCGGGTCAATCTGGATGGGGCATTTTTTACGCTGCGCGCGGCGGCGCGGCAGT TGCTGGCGCAGGGCGATGGGGGTGTGCTGGTCGGGACGGCTTCTGTCGCCGCTATCGAGGGCGCTGCACGCAACGAGCAC TACGCGGCCACCAAGGGTGGATTGATTTCCATGATGCGCGCGCTGTCGGTCGAGTATGCGCGGCATGGGATCCGCGCGCA CTCCGTGCTGCCTGGGTGGATCAAGACGGAGATGACCAGCAATGCGCAGGCCAATGCCACGTTCCAGGAAATGGTTGGGA AGCGGGTGCCTATGCGCAGGTGGGGGGAGGGGGCTGACTTTGCCGGGATTGCGGTGTATCTGATGAGTTCGGCATCGGGG TATCACACGGGGGATACGTTTGTGATTGATGGGGGGTATACGTTGTTTTGA
Upstream 100 bases:
>100_bases CGTCGCATCCGACGATGCCCGCCGACTATGCGGCCTCTTAGCATGATCTGATCCGCCCGAGCACAAGGGCCGGCTCATCC ATCCTCAAAGGAGACAGATC
Downstream 100 bases:
>100_bases GGGTTTTGGGGTAGTTGGTTCTTGGCATGCGCTGCTGTTTCGCCGGCGTAGCCGGCGACCTCCTTTTGTCCTAGCGACAA AAGGGCAAAAGCGCGTGGGC
Product: Short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxygluconate oxidoreductase; KDG oxidoreductase [H]
Number of amino acids: Translated: 256; Mature: 255
Protein sequence:
>256_residues MPFTPFDLTGKVALITGGNGGIGLGMAEGLAQAGADIAIWGTNTQKNAAAAERLAQYGRKVHTAICDVSNESSVAAAMDG TLAALGRLDGCFANAGVSARGTRFEEMGTDDWHRVMRVNLDGAFFTLRAAARQLLAQGDGGVLVGTASVAAIEGAARNEH YAATKGGLISMMRALSVEYARHGIRAHSVLPGWIKTEMTSNAQANATFQEMVGKRVPMRRWGEGADFAGIAVYLMSSASG YHTGDTFVIDGGYTLF
Sequences:
>Translated_256_residues MPFTPFDLTGKVALITGGNGGIGLGMAEGLAQAGADIAIWGTNTQKNAAAAERLAQYGRKVHTAICDVSNESSVAAAMDG TLAALGRLDGCFANAGVSARGTRFEEMGTDDWHRVMRVNLDGAFFTLRAAARQLLAQGDGGVLVGTASVAAIEGAARNEH YAATKGGLISMMRALSVEYARHGIRAHSVLPGWIKTEMTSNAQANATFQEMVGKRVPMRRWGEGADFAGIAVYLMSSASG YHTGDTFVIDGGYTLF >Mature_255_residues PFTPFDLTGKVALITGGNGGIGLGMAEGLAQAGADIAIWGTNTQKNAAAAERLAQYGRKVHTAICDVSNESSVAAAMDGT LAALGRLDGCFANAGVSARGTRFEEMGTDDWHRVMRVNLDGAFFTLRAAARQLLAQGDGGVLVGTASVAAIEGAARNEHY AATKGGLISMMRALSVEYARHGIRAHSVLPGWIKTEMTSNAQANATFQEMVGKRVPMRRWGEGADFAGIAVYLMSSASGY HTGDTFVIDGGYTLF
Specific function: Catalyzes the reduction of 2,5-diketo-3-deoxygluconate (DKII or 4,6-dihydroxy-2,5-dioxohexanoate) into 2-keto-3- deoxygluconate (KDG or 2-dehydro-3-deoxygluconate) with a concomitant oxidation of NADH [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254992, Length=247, Percent_Identity=33.1983805668016, Blast_Score=117, Evalue=9e-27, Organism=Homo sapiens, GI15277342, Length=256, Percent_Identity=30.859375, Blast_Score=110, Evalue=8e-25, Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=27.3469387755102, Blast_Score=101, Evalue=6e-22, Organism=Homo sapiens, GI19923817, Length=261, Percent_Identity=25.6704980842912, Blast_Score=101, Evalue=8e-22, Organism=Homo sapiens, GI4758504, Length=256, Percent_Identity=29.6875, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI66933014, Length=252, Percent_Identity=27.3809523809524, Blast_Score=91, Evalue=8e-19, Organism=Homo sapiens, GI10190704, Length=256, Percent_Identity=30.46875, Blast_Score=88, Evalue=7e-18, Organism=Homo sapiens, GI5031737, Length=251, Percent_Identity=27.4900398406374, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI59889578, Length=197, Percent_Identity=31.9796954314721, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI126723750, Length=252, Percent_Identity=28.5714285714286, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI7705925, Length=246, Percent_Identity=25.2032520325203, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI4503301, Length=256, Percent_Identity=28.90625, Blast_Score=82, Evalue=3e-16, Organism=Homo sapiens, GI31542939, Length=199, Percent_Identity=28.643216080402, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI83715985, Length=255, Percent_Identity=28.2352941176471, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI4504505, Length=194, Percent_Identity=27.319587628866, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI209862901, Length=216, Percent_Identity=27.3148148148148, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI19923983, Length=216, Percent_Identity=27.3148148148148, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI33667109, Length=196, Percent_Identity=28.0612244897959, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI224922801, Length=175, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI40807363, Length=196, Percent_Identity=26.530612244898, Blast_Score=66, Evalue=4e-11, Organism=Escherichia coli, GI1789208, Length=253, Percent_Identity=35.5731225296443, Blast_Score=164, Evalue=7e-42, Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=33.6032388663968, Blast_Score=135, Evalue=2e-33, Organism=Escherichia coli, GI1788459, Length=246, Percent_Identity=32.1138211382114, Blast_Score=134, Evalue=7e-33, Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=33.4645669291339, Blast_Score=133, Evalue=1e-32, Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=30.4, Blast_Score=122, Evalue=3e-29, Organism=Escherichia coli, GI2367175, Length=254, Percent_Identity=33.0708661417323, Blast_Score=105, Evalue=4e-24, Organism=Escherichia coli, GI1787335, Length=251, Percent_Identity=30.6772908366534, Blast_Score=102, Evalue=2e-23, Organism=Escherichia coli, GI1787905, Length=245, Percent_Identity=27.7551020408163, Blast_Score=94, Evalue=6e-21, Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=29.6, Blast_Score=94, Evalue=9e-21, Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=26.2548262548263, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI1787526, Length=243, Percent_Identity=30.4526748971193, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=27.2373540856031, Blast_Score=79, Evalue=2e-16, Organism=Escherichia coli, GI2367365, Length=250, Percent_Identity=28.8, Blast_Score=79, Evalue=3e-16, Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=31.3253012048193, Blast_Score=110, Evalue=9e-25, Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=32.7935222672065, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=28.8537549407115, Blast_Score=100, Evalue=8e-22, Organism=Caenorhabditis elegans, GI17561402, Length=257, Percent_Identity=29.5719844357977, Blast_Score=97, Evalue=8e-21, Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=27.3764258555133, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17531453, Length=269, Percent_Identity=30.4832713754647, Blast_Score=93, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=26.5384615384615, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI17538182, Length=253, Percent_Identity=29.2490118577075, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI115534694, Length=249, Percent_Identity=24.8995983935743, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=27.7566539923954, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=26.1538461538462, Blast_Score=86, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17544670, Length=270, Percent_Identity=27.4074074074074, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI72000259, Length=265, Percent_Identity=26.0377358490566, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=26.9662921348315, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17560332, Length=272, Percent_Identity=27.2058823529412, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=25.4752851711027, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17563726, Length=260, Percent_Identity=25.3846153846154, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=25.7028112449799, Blast_Score=77, Evalue=8e-15, Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=27.6515151515151, Blast_Score=77, Evalue=9e-15, Organism=Caenorhabditis elegans, GI193204405, Length=268, Percent_Identity=25, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17560220, Length=262, Percent_Identity=25.5725190839695, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17564282, Length=192, Percent_Identity=29.1666666666667, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=25.5639097744361, Blast_Score=75, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17538480, Length=264, Percent_Identity=25.7575757575758, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=24.812030075188, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=24.1106719367589, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=24.2424242424242, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17568967, Length=196, Percent_Identity=29.5918367346939, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI193203115, Length=194, Percent_Identity=27.319587628866, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI193203117, Length=195, Percent_Identity=26.6666666666667, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17561272, Length=258, Percent_Identity=25.5813953488372, Blast_Score=64, Evalue=6e-11, Organism=Caenorhabditis elegans, GI17536025, Length=259, Percent_Identity=23.5521235521236, Blast_Score=64, Evalue=9e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=253, Percent_Identity=29.2490118577075, Blast_Score=100, Evalue=4e-22, Organism=Saccharomyces cerevisiae, GI6322861, Length=199, Percent_Identity=29.1457286432161, Blast_Score=65, Evalue=1e-11, Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=29.4354838709677, Blast_Score=108, Evalue=3e-24, Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=31.5789473684211, Blast_Score=108, Evalue=4e-24, Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=29.7619047619048, Blast_Score=103, Evalue=9e-23, Organism=Drosophila melanogaster, GI24643142, Length=250, Percent_Identity=30, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI17737361, Length=258, Percent_Identity=29.0697674418605, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI21357041, Length=247, Percent_Identity=29.1497975708502, Blast_Score=91, Evalue=1e-18, Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=27.9527559055118, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI24665243, Length=211, Percent_Identity=30.3317535545024, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI221331218, Length=205, Percent_Identity=30.7317073170732, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=26.3157894736842, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI24665247, Length=212, Percent_Identity=30.188679245283, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI221331216, Length=206, Percent_Identity=30.5825242718447, Blast_Score=75, Evalue=5e-14, Organism=Drosophila melanogaster, GI21356301, Length=193, Percent_Identity=29.0155440414508, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI28571387, Length=201, Percent_Identity=27.8606965174129, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI24663911, Length=229, Percent_Identity=26.6375545851528, Blast_Score=65, Evalue=6e-11, Organism=Drosophila melanogaster, GI18859837, Length=213, Percent_Identity=27.6995305164319, Blast_Score=64, Evalue=8e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011286 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.127 [H]
Molecular weight: Translated: 26783; Mature: 26651
Theoretical pI: Translated: 7.14; Mature: 7.14
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 4.3 %Met (Translated Protein) 5.1 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 3.9 %Met (Mature Protein) 4.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPFTPFDLTGKVALITGGNGGIGLGMAEGLAQAGADIAIWGTNTQKNAAAAERLAQYGRK CCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHH VHTAICDVSNESSVAAAMDGTLAALGRLDGCFANAGVSARGTRFEEMGTDDWHRVMRVNL HHHHHHCCCCCCCEEHHHHHHHHHHHHHCCHHHCCCCCCCCCCHHHCCCHHHHEEEEEEC DGAFFTLRAAARQLLAQGDGGVLVGTASVAAIEGAARNEHYAATKGGLISMMRALSVEYA CCHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH RHGIRAHSVLPGWIKTEMTSNAQANATFQEMVGKRVPMRRWGEGADFAGIAVYLMSSASG HCCCHHHCCCCCHHHHHHCCCCCCCCHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHCCCC YHTGDTFVIDGGYTLF CCCCCEEEECCCEEEC >Mature Secondary Structure PFTPFDLTGKVALITGGNGGIGLGMAEGLAQAGADIAIWGTNTQKNAAAAERLAQYGRK CCCCCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHH VHTAICDVSNESSVAAAMDGTLAALGRLDGCFANAGVSARGTRFEEMGTDDWHRVMRVNL HHHHHHCCCCCCCEEHHHHHHHHHHHHHCCHHHCCCCCCCCCCHHHCCCHHHHEEEEEEC DGAFFTLRAAARQLLAQGDGGVLVGTASVAAIEGAARNEHYAATKGGLISMMRALSVEYA CCHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH RHGIRAHSVLPGWIKTEMTSNAQANATFQEMVGKRVPMRRWGEGADFAGIAVYLMSSASG HCCCHHHCCCCCHHHHHHCCCCCCCCHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHCCCC YHTGDTFVIDGGYTLF CCCCCEEEECCCEEEC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 1766386 [H]