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The map label for this gene is amn [H]

Identifier: 73539247

GI number: 73539247

Start: 2214223

End: 2215713

Strand: Direct

Name: amn [H]

Synonym: Reut_B5425

Alternate gene names: 73539247

Gene position: 2214223-2215713 (Clockwise)

Preceding gene: 73539245

Following gene: 73539249

Centisome position: 81.22

GC content: 65.79

Gene sequence:

>1491_bases
ATGATGGCTTTCATGAACGCCCCGATCTTCTCTTCTGCCCACCCGGCCGATCAGTTGGCCGAATTCTCCGATGCCGACGC
TGCGCTGGCGCGCATCAAGGAGATCTACAACGCTTCGGTCAGCGCCGTGCGCGCGCGCTTTGACGCGTTCGCCAGCGGCA
AGCCGCTGCCTTCGGCGGCGCATGCGTGCTACCCGTACCTGGGCATTTCCGTGAACATCGAAACCATGGTGACCGACAGC
CGGCCATCATGGGGCACGGTGGCTTATCCGGGCGTCTATGGCACCACGGTGACGCGTCCCGACCTGCTCGCCGATTACTA
CCGCGACCAGATCGAACGGCTGATGCGCTATCACCGCGTGCCCGTGGTGGTGGGCCTCAGCCGCCGGCCGATCCCGCTGC
CGTTCGTGATCGAGGCCTCGACGACCGACATCAGCTATACCCAGGCGCGCGAACTCGAAGTATCCTTCGTGCTGCCGGAG
TTGAGCCGCATCGACGACTCCATTGCCAACGGCACCTACGAACCGGTGCCCGGCGAGGCGTGGCCCCTGTCGCTGTTCCC
TGCCGAGCGCGTGGACCTTGCGCTGCAGCGCCTGTATCACTACACCGGCACCGCGCCTCAGCATTTCCAGCGTTTCGTGC
TGTTCACGAACTACCAGCGTTACGTCGATGAATTCATCGCGCTCGGCCGATCGCTGATGGCCAGCAGCGATGGCAGCGGC
TACACGCGCTTCGTCGAGCCCGGCGACGTCATCCAGCAGCTTGGCGGCGCCGAGCCCGACGACGCCGTGCGTCCCCGCGC
GCTGCCGCAGATGCCGGCCTACCACCTCGTGCGCGAGGACAAGCTCGGCGTGACGCTGGTGAACATCGGCGTGGGTCCGT
CCAATGCGAAGACCATGACCGACCACCTGGCCGTGCTGCGCCCGCACTGCTGGCTCATGATCGGCCATTGCGGTGGCTTG
CGGCGCTCGCAGCAGCTTGGCGACTACGTGCTCGCCCACGCCTATGTGCGCGACGACCACGTGCTCGACCACGACCTGCC
GCCGTGGGTCCCGGTGCCGCCGATCGCGGAAATCCAGGTGGCGCTGCAGGAAGCGGTGGCACGTGTGACTGGCCTGTCCG
GCGGCGAGATGAAGACGCGCATGCGCACGGGCACGGTGGTCTCCACGGACGACCGCAACTGGGAGCTGAAATCCAAGGCA
CTGTACGCGCGCTTCAACCAGTCGCGAGCGATTGCCATCGACATGGAAAGCGCGACCGTGGCGGCCAATGGTTTCCGCCT
GCGCGTGCCGTATGGCACGCTGCTGTGCGTCTCGGACAAGCCGCTGCACGGCGAACTCAAGCTGCGCGGCATGGCCAATG
CGTTCTATCGCCAGCGCGTCAGCCAGCACATGACCATCGGTCTCGAAGCGGTGCGCATCCTGCGCGAGAACGGTGTCGAG
CAACTGCATTCGCGCAAGCTGCGTAGTTTCGACGAGCCGGCATTCCGCTGA

Upstream 100 bases:

>100_bases
AATTGGCGGAGTGTAGCGAGCGGGGGCAGACACGTCAATTTGCCGCAGCACGTACGCAGTGCCGGCGCATCAACCGCTGC
CTCTCGCGCTGCAGCGCGGT

Downstream 100 bases:

>100_bases
ACGATTCCCGCCGCACTGTACGGACAGCGGCTTCGCAATGAAAAAGGCCAGCGCCTCATGCGCTGGCTTTTTTCGTTTCA
CGCAGACTCGGACGAGCCCG

Product: AMP nucleosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MMAFMNAPIFSSAHPADQLAEFSDADAALARIKEIYNASVSAVRARFDAFASGKPLPSAAHACYPYLGISVNIETMVTDS
RPSWGTVAYPGVYGTTVTRPDLLADYYRDQIERLMRYHRVPVVVGLSRRPIPLPFVIEASTTDISYTQARELEVSFVLPE
LSRIDDSIANGTYEPVPGEAWPLSLFPAERVDLALQRLYHYTGTAPQHFQRFVLFTNYQRYVDEFIALGRSLMASSDGSG
YTRFVEPGDVIQQLGGAEPDDAVRPRALPQMPAYHLVREDKLGVTLVNIGVGPSNAKTMTDHLAVLRPHCWLMIGHCGGL
RRSQQLGDYVLAHAYVRDDHVLDHDLPPWVPVPPIAEIQVALQEAVARVTGLSGGEMKTRMRTGTVVSTDDRNWELKSKA
LYARFNQSRAIAIDMESATVAANGFRLRVPYGTLLCVSDKPLHGELKLRGMANAFYRQRVSQHMTIGLEAVRILRENGVE
QLHSRKLRSFDEPAFR

Sequences:

>Translated_496_residues
MMAFMNAPIFSSAHPADQLAEFSDADAALARIKEIYNASVSAVRARFDAFASGKPLPSAAHACYPYLGISVNIETMVTDS
RPSWGTVAYPGVYGTTVTRPDLLADYYRDQIERLMRYHRVPVVVGLSRRPIPLPFVIEASTTDISYTQARELEVSFVLPE
LSRIDDSIANGTYEPVPGEAWPLSLFPAERVDLALQRLYHYTGTAPQHFQRFVLFTNYQRYVDEFIALGRSLMASSDGSG
YTRFVEPGDVIQQLGGAEPDDAVRPRALPQMPAYHLVREDKLGVTLVNIGVGPSNAKTMTDHLAVLRPHCWLMIGHCGGL
RRSQQLGDYVLAHAYVRDDHVLDHDLPPWVPVPPIAEIQVALQEAVARVTGLSGGEMKTRMRTGTVVSTDDRNWELKSKA
LYARFNQSRAIAIDMESATVAANGFRLRVPYGTLLCVSDKPLHGELKLRGMANAFYRQRVSQHMTIGLEAVRILRENGVE
QLHSRKLRSFDEPAFR
>Mature_496_residues
MMAFMNAPIFSSAHPADQLAEFSDADAALARIKEIYNASVSAVRARFDAFASGKPLPSAAHACYPYLGISVNIETMVTDS
RPSWGTVAYPGVYGTTVTRPDLLADYYRDQIERLMRYHRVPVVVGLSRRPIPLPFVIEASTTDISYTQARELEVSFVLPE
LSRIDDSIANGTYEPVPGEAWPLSLFPAERVDLALQRLYHYTGTAPQHFQRFVLFTNYQRYVDEFIALGRSLMASSDGSG
YTRFVEPGDVIQQLGGAEPDDAVRPRALPQMPAYHLVREDKLGVTLVNIGVGPSNAKTMTDHLAVLRPHCWLMIGHCGGL
RRSQQLGDYVLAHAYVRDDHVLDHDLPPWVPVPPIAEIQVALQEAVARVTGLSGGEMKTRMRTGTVVSTDDRNWELKSKA
LYARFNQSRAIAIDMESATVAANGFRLRVPYGTLLCVSDKPLHGELKLRGMANAFYRQRVSQHMTIGLEAVRILRENGVE
QLHSRKLRSFDEPAFR

Specific function: Involved in regulation of AMP concentrations [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788293, Length=476, Percent_Identity=50.4201680672269, Blast_Score=442, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011271
- InterPro:   IPR018953
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF10423 AMNp_N; PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.4 [H]

Molecular weight: Translated: 55243; Mature: 55243

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMAFMNAPIFSSAHPADQLAEFSDADAALARIKEIYNASVSAVRARFDAFASGKPLPSAA
CCCEECCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
HACYPYLGISVNIETMVTDSRPSWGTVAYPGVYGTTVTRPDLLADYYRDQIERLMRYHRV
HHHCCEEEEEEEEEEEEECCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
PVVVGLSRRPIPLPFVIEASTTDISYTQARELEVSFVLPELSRIDDSIANGTYEPVPGEA
CEEEECCCCCCCCEEEEECCCCCCCCCHHHEEEEEEECCHHHHHHHHHHCCCCCCCCCCC
WPLSLFPAERVDLALQRLYHYTGTAPQHFQRFVLFTNYQRYVDEFIALGRSLMASSDGSG
CEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
YTRFVEPGDVIQQLGGAEPDDAVRPRALPQMPAYHLVREDKLGVTLVNIGVGPSNAKTMT
CEEECCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEEECCCCCCCHHHH
DHLAVLRPHCWLMIGHCGGLRRSQQLGDYVLAHAYVRDDHVLDHDLPPWVPVPPIAEIQV
HHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
ALQEAVARVTGLSGGEMKTRMRTGTVVSTDDRNWELKSKALYARFNQSRAIAIDMESATV
HHHHHHHHHHCCCCCCCHHEEECCCEEECCCCCCEEHHHHHHHEECCCCEEEEEECCCEE
AANGFRLRVPYGTLLCVSDKPLHGELKLRGMANAFYRQRVSQHMTIGLEAVRILRENGVE
EECCEEEEECCCEEEEECCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
QLHSRKLRSFDEPAFR
HHHHHHHHCCCCCCCC
>Mature Secondary Structure
MMAFMNAPIFSSAHPADQLAEFSDADAALARIKEIYNASVSAVRARFDAFASGKPLPSAA
CCCEECCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
HACYPYLGISVNIETMVTDSRPSWGTVAYPGVYGTTVTRPDLLADYYRDQIERLMRYHRV
HHHCCEEEEEEEEEEEEECCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
PVVVGLSRRPIPLPFVIEASTTDISYTQARELEVSFVLPELSRIDDSIANGTYEPVPGEA
CEEEECCCCCCCCEEEEECCCCCCCCCHHHEEEEEEECCHHHHHHHHHHCCCCCCCCCCC
WPLSLFPAERVDLALQRLYHYTGTAPQHFQRFVLFTNYQRYVDEFIALGRSLMASSDGSG
CEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
YTRFVEPGDVIQQLGGAEPDDAVRPRALPQMPAYHLVREDKLGVTLVNIGVGPSNAKTMT
CEEECCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEEECCCCCCCHHHH
DHLAVLRPHCWLMIGHCGGLRRSQQLGDYVLAHAYVRDDHVLDHDLPPWVPVPPIAEIQV
HHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
ALQEAVARVTGLSGGEMKTRMRTGTVVSTDDRNWELKSKALYARFNQSRAIAIDMESATV
HHHHHHHHHHCCCCCCCHHEEECCCEEECCCCCCEEHHHHHHHEECCCCEEEEEECCCEE
AANGFRLRVPYGTLLCVSDKPLHGELKLRGMANAFYRQRVSQHMTIGLEAVRILRENGVE
EECCEEEEECCCEEEEECCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
QLHSRKLRSFDEPAFR
HHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]