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The map label for this gene is ybhD [H]

Identifier: 73539219

GI number: 73539219

Start: 2182823

End: 2183716

Strand: Reverse

Name: ybhD [H]

Synonym: Reut_B5397

Alternate gene names: 73539219

Gene position: 2183716-2182823 (Counterclockwise)

Preceding gene: 73539224

Following gene: 73539211

Centisome position: 80.1

GC content: 68.9

Gene sequence:

>894_bases
ATGAACCTTTCCGTCAAACACCTGCGCGCCTTCGTGGCGCTTGCCACTCACCGCAACTTCACGCGCGCGGCGCGGGCGTG
CCATCTGTCGCAGTCGGCATTCAGCGCGCTGGTCCAGACCCTTGAGGAACAGGCCGGCAGCCGCCTGTTCGAACGCACCA
CGCGGCACGTGGAACTGAGCGCCGATGGCATGCGCTTCGAGGAAACCGCGCGGCGCCTGCTGGGAGATTTCGAGGCCGCC
TTCGAGGACCTGCGGGCGCACGCGGAGCGCCGCAAGGGACGCGTCAGCATCGCTGCACTGCCTTCGATCGCGGGCGGCGA
CCTGCCGCCGCTGCTGGCGGCATTCCGGCAGCGTTATCCGGGGATTGCGCTGGAGTTATTCGACCAGCTCGCCGATGGCT
GCATCGACCTGGTACGGCGTGGGCGCGCCGACTTTGCGCTGGCGCCTGCGCCCGTGCAGGACGATGACCTGCGTGTCGAG
CCCTTGGTGCATGACACCTTCCATCTGGTCTGCCCGACCACGCACGTGCTTGCGCGCAAGCGCCGCATCACGCCGCAGAT
GCTCGCGGGACAGCCGTTCATCCACCTGTCGCGGACCAGCAGCGTGCGCCAGCATCTGGACGCCGCGCTGCATCCGCTCA
AGCTCAGCAGCGTGATGGAAGTCGAGCACCTGGCCACGGTCGCCGCACTCGTGCAGGCAGGCCTGGGCGTGAGCGTGGTG
CCGTCGCTGGCGCTGTTCCAGTTCCAGCGCGACGGTCTGGCGGTCCGGCCGCTGCAGATGCCGTCGCTGGTCCGGGACAT
CTGCCTGGTGCGGCTACGCGACCGTGGCGACTCGGCCGCGGCGGCGGCGATGATCGATTGCCTGCATGTCCACTACGGCC
GGCGGCGCACTTGA

Upstream 100 bases:

>100_bases
TGGTCGATGTTCCAGCTCATTCTAGGCCGGCATCAGTCAGCCAAAAAATGGATTATTTGGATTAATCTAGTGACTTCCCC
GATGAATCTGCCAGGCGGCC

Downstream 100 bases:

>100_bases
GGGTACGCAGAATTGGGTACGCTTTGTGTGGATTGGCACCGCTTCCACGCCTTGTCCGGTGCGGCATTGATGGCAGGGCG
AAGCACCACGCAGAAATGGG

Product: regulatory protein LysR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MNLSVKHLRAFVALATHRNFTRAARACHLSQSAFSALVQTLEEQAGSRLFERTTRHVELSADGMRFEETARRLLGDFEAA
FEDLRAHAERRKGRVSIAALPSIAGGDLPPLLAAFRQRYPGIALELFDQLADGCIDLVRRGRADFALAPAPVQDDDLRVE
PLVHDTFHLVCPTTHVLARKRRITPQMLAGQPFIHLSRTSSVRQHLDAALHPLKLSSVMEVEHLATVAALVQAGLGVSVV
PSLALFQFQRDGLAVRPLQMPSLVRDICLVRLRDRGDSAAAAAMIDCLHVHYGRRRT

Sequences:

>Translated_297_residues
MNLSVKHLRAFVALATHRNFTRAARACHLSQSAFSALVQTLEEQAGSRLFERTTRHVELSADGMRFEETARRLLGDFEAA
FEDLRAHAERRKGRVSIAALPSIAGGDLPPLLAAFRQRYPGIALELFDQLADGCIDLVRRGRADFALAPAPVQDDDLRVE
PLVHDTFHLVCPTTHVLARKRRITPQMLAGQPFIHLSRTSSVRQHLDAALHPLKLSSVMEVEHLATVAALVQAGLGVSVV
PSLALFQFQRDGLAVRPLQMPSLVRDICLVRLRDRGDSAAAAAMIDCLHVHYGRRRT
>Mature_297_residues
MNLSVKHLRAFVALATHRNFTRAARACHLSQSAFSALVQTLEEQAGSRLFERTTRHVELSADGMRFEETARRLLGDFEAA
FEDLRAHAERRKGRVSIAALPSIAGGDLPPLLAAFRQRYPGIALELFDQLADGCIDLVRRGRADFALAPAPVQDDDLRVE
PLVHDTFHLVCPTTHVLARKRRITPQMLAGQPFIHLSRTSSVRQHLDAALHPLKLSSVMEVEHLATVAALVQAGLGVSVV
PSLALFQFQRDGLAVRPLQMPSLVRDICLVRLRDRGDSAAAAAMIDCLHVHYGRRRT

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=283, Percent_Identity=31.4487632508834, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1788748, Length=290, Percent_Identity=33.1034482758621, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI157672245, Length=285, Percent_Identity=31.2280701754386, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1789204, Length=292, Percent_Identity=33.5616438356164, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1788887, Length=274, Percent_Identity=30.6569343065693, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1787879, Length=292, Percent_Identity=29.7945205479452, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1790399, Length=292, Percent_Identity=28.0821917808219, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1787530, Length=268, Percent_Identity=28.3582089552239, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1788481, Length=289, Percent_Identity=27.3356401384083, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787601, Length=178, Percent_Identity=27.5280898876405, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1790783, Length=268, Percent_Identity=27.6119402985075, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1789173, Length=194, Percent_Identity=30.4123711340206, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786401, Length=302, Percent_Identity=24.8344370860927, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790262, Length=258, Percent_Identity=26.3565891472868, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI145693193, Length=260, Percent_Identity=27.6923076923077, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87081904, Length=206, Percent_Identity=28.1553398058252, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI2367136, Length=262, Percent_Identity=24.8091603053435, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1790208, Length=252, Percent_Identity=27.3809523809524, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787806, Length=244, Percent_Identity=23.7704918032787, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788297, Length=249, Percent_Identity=25.7028112449799, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788706, Length=134, Percent_Identity=32.089552238806, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787589, Length=134, Percent_Identity=32.8358208955224, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1789639, Length=143, Percent_Identity=28.6713286713287, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788626, Length=248, Percent_Identity=28.6290322580645, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32844; Mature: 32844

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLSVKHLRAFVALATHRNFTRAARACHLSQSAFSALVQTLEEQAGSRLFERTTRHVELS
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEC
ADGMRFEETARRLLGDFEAAFEDLRAHAERRKGRVSIAALPSIAGGDLPPLLAAFRQRYP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHCC
GIALELFDQLADGCIDLVRRGRADFALAPAPVQDDDLRVEPLVHDTFHLVCPTTHVLARK
CHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCEECCHHHHHHHHHCCHHHHHHHH
RRITPQMLAGQPFIHLSRTSSVRQHLDAALHPLKLSSVMEVEHLATVAALVQAGLGVSVV
HCCCHHHHCCCCCEEEHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
PSLALFQFQRDGLAVRPLQMPSLVRDICLVRLRDRGDSAAAAAMIDCLHVHYGRRRT
HHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNLSVKHLRAFVALATHRNFTRAARACHLSQSAFSALVQTLEEQAGSRLFERTTRHVELS
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEC
ADGMRFEETARRLLGDFEAAFEDLRAHAERRKGRVSIAALPSIAGGDLPPLLAAFRQRYP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHCC
GIALELFDQLADGCIDLVRRGRADFALAPAPVQDDDLRVEPLVHDTFHLVCPTTHVLARK
CHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCEECCHHHHHHHHHCCHHHHHHHH
RRITPQMLAGQPFIHLSRTSSVRQHLDAALHPLKLSSVMEVEHLATVAALVQAGLGVSVV
HCCCHHHHCCCCCEEEHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
PSLALFQFQRDGLAVRPLQMPSLVRDICLVRLRDRGDSAAAAAMIDCLHVHYGRRRT
HHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]