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The map label for this gene is cynX [H]

Identifier: 73539204

GI number: 73539204

Start: 2167068

End: 2168294

Strand: Reverse

Name: cynX [H]

Synonym: Reut_B5382

Alternate gene names: 73539204

Gene position: 2168294-2167068 (Counterclockwise)

Preceding gene: 73539205

Following gene: 73539203

Centisome position: 79.54

GC content: 72.45

Gene sequence:

>1227_bases
ATGGCGGTCGGCGCGCATGAGGCGGATCGGGCGCCGGCACGCTGGCTGGTCCTGGCCGCGGTCGTGGCGATTGGCCTGAA
CCTGCGTCCGTTCCTGACGGCGGTTGGTCCGCTTGCCGCCACCATCCGCGCGGGCACGGGACTGGACTACGAAGGCATGG
CGTGGCTCACGCTGCTGCCGATGCTGCTGATGGGCGTCGGTGCTTTTGCCGCGCCGGCCATCCGCCAGCGGCTTGGCGCG
CGCCGGGCGGTACTGGGCGCGCTGGCCATGCTTGGCGCAGGATCGGCCTTGCGCGCGCTGGCGACGGACGGCGCCTTGCT
GGTGGCGACCGCGGCCGTGTGCGGCCTTGGCGTTGCCGTGGTGCAGGCAGCCTGCCCGGGCCTCATCAAGCAGGAATTCC
CGCGGCGCGTCGCACCGGTCATGGGCCTGTATTCGGCCGCGCTAATGGGCGGCGGCGCGCTTGGCGCGCAGATCGCACCG
GTCATCGCCAACCTGTCCGGCTCATGGCAGCAGGGCCTGGCCTGGTGGGCGCTGCCGGTCATGGCAGCGCTGGGCCTCGC
ATGGCGGGCGTTGCCGGCGCCGGCCGGCCCGGCACCGGCCACACGTGCCACGCACCGGCCCGCAAGGCAGCTTCTGCGCC
GGCGCCGGACGTGGATGCTGATGGTGTGTTTCGGCGTGATGAACGGCGGCTATGCCTCGCTCGTTGCGTGGCTGGCGCCG
TTCTACCAACAGCACGGCTGGAGCGTCGCACGCAGCGGCAGCCTGGTAGCCGTGATGGCGATCGCCCAGGCGGCGGCCGC
CCTGCTGTTGCCCACCCTGGCAGCGGCCCGCCAGGATCGCCGCGCATGGATGGCGGCCGCGCTCGTCATGCAGGCCGCGG
GCTTTGCCGGCCTGGCCCTGTGGCCGGAATGGTCGCCGTATGCCTGGGCTGCGATCGGCGGTGCCGGGCTCGGCGGCTGC
TTTGCGCTGTACCTGGTGGTGGCGCTGGACCATCTGCCCGATCCGGAAAGCGCCGGCGCACTGGGCGCATTGATGCAGGG
TGGTGGCTTCCTGCTGGCGTCACTGGCGCCGTGGATCACGGCCGCGCTGCATTCGCGCACCGGCGATTTCATGGCGGGCT
GGTGGTTCCACCTTGGCTGCGTCGCGTTCGTGGCCGCGCTCACGCTGCGCCTGAACCCGGCGCGCTATGCCGTGTCGATG
ACGGGCGCCCCGTCGATGGCCCGATAG

Upstream 100 bases:

>100_bases
CGCCTGCCGCTGATACCGCCGCCGCTTCCACTGCAGCGCGTGCCGGTCGATATCTCCGCCGCGCAGCTCTACGGCACGCG
CCAGCCCCGTGGCTGAGCGC

Downstream 100 bases:

>100_bases
GTCCTGCACGGCAGGAACTGCATCGCACTGGCCGGGCTCCACGTCAGCGCGGCGTAGCGCGCTCGATGATTGCGCTGACG
TCGGCGGAATCGGGGTCGGC

Product: major facilitator transporter

Products: Proton [Cytoplasm]; Cyanate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MAVGAHEADRAPARWLVLAAVVAIGLNLRPFLTAVGPLAATIRAGTGLDYEGMAWLTLLPMLLMGVGAFAAPAIRQRLGA
RRAVLGALAMLGAGSALRALATDGALLVATAAVCGLGVAVVQAACPGLIKQEFPRRVAPVMGLYSAALMGGGALGAQIAP
VIANLSGSWQQGLAWWALPVMAALGLAWRALPAPAGPAPATRATHRPARQLLRRRRTWMLMVCFGVMNGGYASLVAWLAP
FYQQHGWSVARSGSLVAVMAIAQAAAALLLPTLAAARQDRRAWMAAALVMQAAGFAGLALWPEWSPYAWAAIGGAGLGGC
FALYLVVALDHLPDPESAGALGALMQGGGFLLASLAPWITAALHSRTGDFMAGWWFHLGCVAFVAALTLRLNPARYAVSM
TGAPSMAR

Sequences:

>Translated_408_residues
MAVGAHEADRAPARWLVLAAVVAIGLNLRPFLTAVGPLAATIRAGTGLDYEGMAWLTLLPMLLMGVGAFAAPAIRQRLGA
RRAVLGALAMLGAGSALRALATDGALLVATAAVCGLGVAVVQAACPGLIKQEFPRRVAPVMGLYSAALMGGGALGAQIAP
VIANLSGSWQQGLAWWALPVMAALGLAWRALPAPAGPAPATRATHRPARQLLRRRRTWMLMVCFGVMNGGYASLVAWLAP
FYQQHGWSVARSGSLVAVMAIAQAAAALLLPTLAAARQDRRAWMAAALVMQAAGFAGLALWPEWSPYAWAAIGGAGLGGC
FALYLVVALDHLPDPESAGALGALMQGGGFLLASLAPWITAALHSRTGDFMAGWWFHLGCVAFVAALTLRLNPARYAVSM
TGAPSMAR
>Mature_407_residues
AVGAHEADRAPARWLVLAAVVAIGLNLRPFLTAVGPLAATIRAGTGLDYEGMAWLTLLPMLLMGVGAFAAPAIRQRLGAR
RAVLGALAMLGAGSALRALATDGALLVATAAVCGLGVAVVQAACPGLIKQEFPRRVAPVMGLYSAALMGGGALGAQIAPV
IANLSGSWQQGLAWWALPVMAALGLAWRALPAPAGPAPATRATHRPARQLLRRRRTWMLMVCFGVMNGGYASLVAWLAPF
YQQHGWSVARSGSLVAVMAIAQAAAALLLPTLAAARQDRRAWMAAALVMQAAGFAGLALWPEWSPYAWAAIGGAGLGGCF
ALYLVVALDHLPDPESAGALGALMQGGGFLLASLAPWITAALHSRTGDFMAGWWFHLGCVAFVAALTLRLNPARYAVSMT
GAPSMAR

Specific function: This protein is part of an active transport system that transports exogenous cyanate into E.coli cells [H]

COG id: COG2807

COG function: function code P; Cyanate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Cyanate porter (TC 2.A.1.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786536, Length=380, Percent_Identity=44.4736842105263, Blast_Score=245, Evalue=3e-66,
Organism=Escherichia coli, GI1788092, Length=361, Percent_Identity=30.7479224376731, Blast_Score=109, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004747
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42119; Mature: 41988

Theoretical pI: Translated: 11.50; Mature: 11.50

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVGAHEADRAPARWLVLAAVVAIGLNLRPFLTAVGPLAATIRAGTGLDYEGMAWLTLLP
CCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
MLLMGVGAFAAPAIRQRLGARRAVLGALAMLGAGSALRALATDGALLVATAAVCGLGVAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHH
VQAACPGLIKQEFPRRVAPVMGLYSAALMGGGALGAQIAPVIANLSGSWQQGLAWWALPV
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
MAALGLAWRALPAPAGPAPATRATHRPARQLLRRRRTWMLMVCFGVMNGGYASLVAWLAP
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FYQQHGWSVARSGSLVAVMAIAQAAAALLLPTLAAARQDRRAWMAAALVMQAAGFAGLAL
HHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
WPEWSPYAWAAIGGAGLGGCFALYLVVALDHLPDPESAGALGALMQGGGFLLASLAPWIT
CCCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHHH
AALHSRTGDFMAGWWFHLGCVAFVAALTLRLNPARYAVSMTGAPSMAR
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEECCCCCCCC
>Mature Secondary Structure 
AVGAHEADRAPARWLVLAAVVAIGLNLRPFLTAVGPLAATIRAGTGLDYEGMAWLTLLP
CCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
MLLMGVGAFAAPAIRQRLGARRAVLGALAMLGAGSALRALATDGALLVATAAVCGLGVAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHH
VQAACPGLIKQEFPRRVAPVMGLYSAALMGGGALGAQIAPVIANLSGSWQQGLAWWALPV
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
MAALGLAWRALPAPAGPAPATRATHRPARQLLRRRRTWMLMVCFGVMNGGYASLVAWLAP
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FYQQHGWSVARSGSLVAVMAIAQAAAALLLPTLAAARQDRRAWMAAALVMQAAGFAGLAL
HHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
WPEWSPYAWAAIGGAGLGGCFALYLVVALDHLPDPESAGALGALMQGGGFLLASLAPWIT
CCCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHHH
AALHSRTGDFMAGWWFHLGCVAFVAALTLRLNPARYAVSMTGAPSMAR
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; Cyanate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + Cyanate [Periplasm] = Proton [Cytoplasm] + Cyanate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3049588; 9278503 [H]