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The map label for this gene is epsA [H]

Identifier: 73539192

GI number: 73539192

Start: 2149622

End: 2150797

Strand: Reverse

Name: epsA [H]

Synonym: Reut_B5370

Alternate gene names: 73539192

Gene position: 2150797-2149622 (Counterclockwise)

Preceding gene: 73539194

Following gene: 73539191

Centisome position: 78.89

GC content: 59.69

Gene sequence:

>1176_bases
ATGAGACCGATCCCTGAAGGAAAGGAATCAGGCGGGCTGGGCCTGGTGAGGCACTGCCATGCCACCGCGTCGAAGTTAGC
CGCGATTGTCGTGGTCATGTTGTTGGGTGCATGCGCGGCGTCACCCGGCATGTACTTTGATTCCAAGGCGAAAGTTTCAG
CGATCGGGCCCGACGCCGTGCCGAACGTGACTCCGATCACGCTGGATTTGGTGCGCGAACTGAAGACCAAGCCAAAGGTG
GTGAATGAAAACGTGGAGCAATTGTTCGCAAAGCCCGAGCCCTATCGGATCGGCGCTGGCGACATCCTTTCGGTGGTGGT
GTGGGACCACCCCGAAATGGTCTTTCCTACGCAAACGTACAGCATTGCCGCAGCGTTCGAGGTCCCGCAATCCAGCGGTG
GGTCCAATATGCCTGGGTACGTTGTCAGCGCACAAGGTGACATCCAGTTTCCCTACGCTGGCGTGATGCATGTGGCAGGC
CTGACAGCAGGTGAAGTCAGAGACCGTATGGCTCGCGTTCTCTCGCGCGTAGTGAGGGATCCCCAGATGACCGTCCGGGT
GCTGGGATTTCGCAGCCAGCGTGTGTATGTCGACGGCGAGGTAAAGACTCCCGGCATGCAGGCTATCGACGATGCGCCCA
TGACACTGGTCGAGGCACTCAACCGCGCCGGGGGCGTACTGAACCAAACCGGTGATAACAGCCGTGTGCGTGTTACCCGC
GGGGAGCAAAGCTGGTTTGTCAACATCCCGGCACTGCTGGCCAAGGGCGTTGATCCCGCGCACATCCTCCTTCGGTCCGG
CGACATTGTTCGCGTAGAACAACGGGAAGACAACAAGATCTTCGTCACCGGGGAAGTGGTGCGCCCTACCTCGCTGCTGA
TGCGAAATGGCCGTATGACCCTGAACGAGGCATTGGGGGACGCTGGCGGTGTCAACCCCGGCTCTGCCAACGCTGAGCAG
ATTTTTGTGATCCGCAAGATGGCCGACGGGGAACCAAAGGTGTACCACCTTGACGGAAACTCGCCGGTTGCGCTTGCTAT
CGCCGAAGGCTTTGAGCTCGAGCCCAAGGATGTCGTCTATGTCGACGCGCGTGACCTTGTGCGGTGGAGCCGGGTGATCA
ATCTGCTTCTTCCCATCACGCAGCCAGTGGTCGGCGCAGCCAGCGTTGTCAAATAG

Upstream 100 bases:

>100_bases
TGTGCGAGAACGCACCGAAGCATGGTCGAAGCCTTCCTACGATGCAAAGGCGGGCATGCACTGGGCGCGATGCCCGGCCG
TACTCAAGAAGGAGACTGCT

Downstream 100 bases:

>100_bases
CCAAGTGCATCGCCATGATCCGGTCAATCCTTATCATCTGCACCGGCAATGTCTGTCGTAGCCCCATGGCCGCATGCCTG
TTCAGGCGCGCCCTGCCCGA

Product: polysaccharide export protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MRPIPEGKESGGLGLVRHCHATASKLAAIVVVMLLGACAASPGMYFDSKAKVSAIGPDAVPNVTPITLDLVRELKTKPKV
VNENVEQLFAKPEPYRIGAGDILSVVVWDHPEMVFPTQTYSIAAAFEVPQSSGGSNMPGYVVSAQGDIQFPYAGVMHVAG
LTAGEVRDRMARVLSRVVRDPQMTVRVLGFRSQRVYVDGEVKTPGMQAIDDAPMTLVEALNRAGGVLNQTGDNSRVRVTR
GEQSWFVNIPALLAKGVDPAHILLRSGDIVRVEQREDNKIFVTGEVVRPTSLLMRNGRMTLNEALGDAGGVNPGSANAEQ
IFVIRKMADGEPKVYHLDGNSPVALAIAEGFELEPKDVVYVDARDLVRWSRVINLLLPITQPVVGAASVVK

Sequences:

>Translated_391_residues
MRPIPEGKESGGLGLVRHCHATASKLAAIVVVMLLGACAASPGMYFDSKAKVSAIGPDAVPNVTPITLDLVRELKTKPKV
VNENVEQLFAKPEPYRIGAGDILSVVVWDHPEMVFPTQTYSIAAAFEVPQSSGGSNMPGYVVSAQGDIQFPYAGVMHVAG
LTAGEVRDRMARVLSRVVRDPQMTVRVLGFRSQRVYVDGEVKTPGMQAIDDAPMTLVEALNRAGGVLNQTGDNSRVRVTR
GEQSWFVNIPALLAKGVDPAHILLRSGDIVRVEQREDNKIFVTGEVVRPTSLLMRNGRMTLNEALGDAGGVNPGSANAEQ
IFVIRKMADGEPKVYHLDGNSPVALAIAEGFELEPKDVVYVDARDLVRWSRVINLLLPITQPVVGAASVVK
>Mature_391_residues
MRPIPEGKESGGLGLVRHCHATASKLAAIVVVMLLGACAASPGMYFDSKAKVSAIGPDAVPNVTPITLDLVRELKTKPKV
VNENVEQLFAKPEPYRIGAGDILSVVVWDHPEMVFPTQTYSIAAAFEVPQSSGGSNMPGYVVSAQGDIQFPYAGVMHVAG
LTAGEVRDRMARVLSRVVRDPQMTVRVLGFRSQRVYVDGEVKTPGMQAIDDAPMTLVEALNRAGGVLNQTGDNSRVRVTR
GEQSWFVNIPALLAKGVDPAHILLRSGDIVRVEQREDNKIFVTGEVVRPTSLLMRNGRMTLNEALGDAGGVNPGSANAEQ
IFVIRKMADGEPKVYHLDGNSPVALAIAEGFELEPKDVVYVDARDLVRWSRVINLLLPITQPVVGAASVVK

Specific function: Probably involved in polymerization and/or export of exopolysaccharide EPS I which functions as a virulence factor [H]

COG id: COG1596

COG function: function code M; Periplasmic protein involved in polysaccharide export

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BexD/CtrA/VexA family [H]

Homologues:

Organism=Escherichia coli, GI1787218, Length=361, Percent_Identity=37.9501385041551, Blast_Score=215, Evalue=3e-57,
Organism=Escherichia coli, GI1788376, Length=365, Percent_Identity=36.1643835616438, Blast_Score=211, Evalue=5e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003715
- InterPro:   IPR019554 [H]

Pfam domain/function: PF02563 Poly_export; PF10531 SLBB [H]

EC number: NA

Molecular weight: Translated: 42046; Mature: 42046

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPIPEGKESGGLGLVRHCHATASKLAAIVVVMLLGACAASPGMYFDSKAKVSAIGPDAV
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEEEECCCCC
PNVTPITLDLVRELKTKPKVVNENVEQLFAKPEPYRIGAGDILSVVVWDHPEMVFPTQTY
CCCCCHHHHHHHHHHCCCCHHHCCHHHHHCCCCCEEECCCCEEEEEEECCCCEEECCCCE
SIAAAFEVPQSSGGSNMPGYVVSAQGDIQFPYAGVMHVAGLTAGEVRDRMARVLSRVVRD
EEEEEEECCCCCCCCCCCCEEEECCCCEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
PQMTVRVLGFRSQRVYVDGEVKTPGMQAIDDAPMTLVEALNRAGGVLNQTGDNSRVRVTR
CCCEEEEEEECCCEEEECCCCCCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEE
GEQSWFVNIPALLAKGVDPAHILLRSGDIVRVEQREDNKIFVTGEVVRPTSLLMRNGRMT
CCCCEEEECHHHHHCCCCHHEEEEECCCEEEEEECCCCEEEEEECCCCCHHHHHHCCCEE
LNEALGDAGGVNPGSANAEQIFVIRKMADGEPKVYHLDGNSPVALAIAEGFELEPKDVVY
HHHHCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEEECCCCCEEEEEECCCCCCCCCEEE
VDARDLVRWSRVINLLLPITQPVVGAASVVK
ECHHHHHHHHHHHHHHHHHHCCHHCHHHHCC
>Mature Secondary Structure
MRPIPEGKESGGLGLVRHCHATASKLAAIVVVMLLGACAASPGMYFDSKAKVSAIGPDAV
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEEEECCCCC
PNVTPITLDLVRELKTKPKVVNENVEQLFAKPEPYRIGAGDILSVVVWDHPEMVFPTQTY
CCCCCHHHHHHHHHHCCCCHHHCCHHHHHCCCCCEEECCCCEEEEEEECCCCEEECCCCE
SIAAAFEVPQSSGGSNMPGYVVSAQGDIQFPYAGVMHVAGLTAGEVRDRMARVLSRVVRD
EEEEEEECCCCCCCCCCCCEEEECCCCEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
PQMTVRVLGFRSQRVYVDGEVKTPGMQAIDDAPMTLVEALNRAGGVLNQTGDNSRVRVTR
CCCEEEEEEECCCEEEECCCCCCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEE
GEQSWFVNIPALLAKGVDPAHILLRSGDIVRVEQREDNKIFVTGEVVRPTSLLMRNGRMT
CCCCEEEECHHHHHCCCCHHEEEEECCCEEEEEECCCCEEEEEECCCCCHHHHHHCCCEE
LNEALGDAGGVNPGSANAEQIFVIRKMADGEPKVYHLDGNSPVALAIAEGFELEPKDVVY
HHHHCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEEECCCCCEEEEEECCCCCCCCCEEE
VDARDLVRWSRVINLLLPITQPVVGAASVVK
ECHHHHHHHHHHHHHHHHHHCCHHCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]