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The map label for this gene is mhpA [H]

Identifier: 73539144

GI number: 73539144

Start: 2086980

End: 2088665

Strand: Direct

Name: mhpA [H]

Synonym: Reut_B5321

Alternate gene names: 73539144

Gene position: 2086980-2088665 (Clockwise)

Preceding gene: 73539140

Following gene: 73539145

Centisome position: 76.55

GC content: 67.32

Gene sequence:

>1686_bases
ATGACAGATCGTTCCGCCCCCGCCCCCGCCCCCGCCTCCGCTGCGCCACCCGTGCCGCCCGTCGCCGACGCGCGGCCATG
GCCGTCCGAGGTTCCTGTGCTGATCGCCGGTGGTGGCCCGGTCGGCCTGGCGCTGAGCGCCCTGCTCGCGCGCCAGGGCA
TCGCCTCGCTCGTGATCGAAGCTGATGGCGGGTACTGCGCGGGCAGCCGTGCGATCTGCATGTCGCGCCGATCGCTGGAG
ATCCTCGGCTGGGTTGGCGCGGACCAGGCCACGGTCGACAAGGGCCTGCCGTGGGTCGGCGGGCGCAGCTACTACCGCGA
TGCCGAAGTGCTGCATTTCCGCATGCCGAGCGAACCCGGGGAGCGCTTCGCGCCGATGGTCAATATCCAGCAGTACTACC
TGGAAGCGTTCGCGCATGAGGCTGCGCTTGCCTGCGGGACACTTGCCGATGTGCGCTTCAACGCGCGTGTCATCACCGTG
CGGCAAGATGCGGATAGCGTCAGCGTGAACATCGAAAGCGCAGAAGGCACACAAGAAGTCCGCGCCCAGTGGCTCATCGC
CTGCGACGGCGGCCGCAGCACCGTGCGCGAGCAGCTCGGACTGCGCATGGAAGGCACGCAATACGAAGGCCGCTATGTGA
TCGTCGATATCGTGCAAAAGACAAAGCGCGACGTGGAGCGGCTGGCGTGGTTCGATCCGCCGTCAAACCCCGGCTCGACC
ATCCTGATGCATCGCCAGCCCGACGACGTCTGGCGCATCGACTACCAGATCCGCGACGACGAGGACCCCATCGAGGCCGT
CAAGCCCGAGAACGTGCTGCCGCGCGTGCAGAGCCATCTCGACATGATCGGCGAGACCGAACCGTGGGAGCCGCTGTGGA
TCTCCATTTACAACGCCAAGTGCCTGACGCTGGATGCGTACCGGCACGGGCGAGTGCTGTTCGCGGGCGACGCGGCGCAC
CTGGTGCCGATCTTCGGCGTGCGCGGGCTCAACTCCGGACTCGATGATGCGGGCAATCTGGCGTGGAAGCTCGCGTGGGT
CATCCAGGGCCGTGCCGGTGCAAGCCTGCTCGACAGCTATTCCACCGAGCGCGTGCATGCCACGCGGCAGAACATCGCCC
ACGGCGCCAAGAGCACGGAGTTCATGGCGCCGCCGAACTTCGCCTTCGAATTGATGCGGCAGGCCACGCTGCGTCTGGCG
CTCGATGAACCGGGCGTACGCTCGCTGATCAATCCGCGTCAGTCGGCGCCGATCGCGTATGCGGACTCGGCGCTGAATGG
TCCGTCCGACTTCGGCGGCGAGTGCGCCGCTGCGGCGCCGGGCATGCCCGCGCCGGAAGCCCGCGTGGACCGCGGACACC
TGACCGCCAGCTTCGGCCATCGCTTCACGCTGCTGTGGTTTGGCGATAGCGTACCGGGAGACATCGCCGCCATGGCGCAG
GCGCATGCCGCTGGCGTGCAGTTGCTCGCCATAAATCCCGCTGGCAGTACGGCTCGGGAAGGGATGCTGGTCGATGTCGA
CGGGCAGGCCTTTCAGCGCTATGGCGCACAGCCTGGCACGTTGTACGTGATTCGTCCGGACGGCTATGTCCTGGCGCGCT
GGCGCACGCCGCAACCGGATCAGATCCGCACCGTCCTCGCCCCTTTCCTGCAAACCCCTTCTGACGGAGCCCGCCATGCA
AGCTGA

Upstream 100 bases:

>100_bases
AGCATAGGCGAGAGTATCGAACGCCGGGGTTTACGCTAGTTTCGTGCGCAACTATTATGTCGATATAGTTGCGCACACAA
CTACATTGCCGAGGTTGTCC

Downstream 100 bases:

>100_bases
CGAACTCGATCTCGCCTACACCCGCCTGTGCGAAACCATGGCCCGGGTCGGCCGGGACAAGACGCCGCTGCTGCTGGCCA
TGGTGTGCCTCGGCCTGATG

Product: FAD-dependent oxidoreductase

Products: NA

Alternate protein names: 3-HCI hydroxylase; 3-HPP hydroxylase; Flavin-type monooxygenase [H]

Number of amino acids: Translated: 561; Mature: 560

Protein sequence:

>561_residues
MTDRSAPAPAPASAAPPVPPVADARPWPSEVPVLIAGGGPVGLALSALLARQGIASLVIEADGGYCAGSRAICMSRRSLE
ILGWVGADQATVDKGLPWVGGRSYYRDAEVLHFRMPSEPGERFAPMVNIQQYYLEAFAHEAALACGTLADVRFNARVITV
RQDADSVSVNIESAEGTQEVRAQWLIACDGGRSTVREQLGLRMEGTQYEGRYVIVDIVQKTKRDVERLAWFDPPSNPGST
ILMHRQPDDVWRIDYQIRDDEDPIEAVKPENVLPRVQSHLDMIGETEPWEPLWISIYNAKCLTLDAYRHGRVLFAGDAAH
LVPIFGVRGLNSGLDDAGNLAWKLAWVIQGRAGASLLDSYSTERVHATRQNIAHGAKSTEFMAPPNFAFELMRQATLRLA
LDEPGVRSLINPRQSAPIAYADSALNGPSDFGGECAAAAPGMPAPEARVDRGHLTASFGHRFTLLWFGDSVPGDIAAMAQ
AHAAGVQLLAINPAGSTAREGMLVDVDGQAFQRYGAQPGTLYVIRPDGYVLARWRTPQPDQIRTVLAPFLQTPSDGARHA
S

Sequences:

>Translated_561_residues
MTDRSAPAPAPASAAPPVPPVADARPWPSEVPVLIAGGGPVGLALSALLARQGIASLVIEADGGYCAGSRAICMSRRSLE
ILGWVGADQATVDKGLPWVGGRSYYRDAEVLHFRMPSEPGERFAPMVNIQQYYLEAFAHEAALACGTLADVRFNARVITV
RQDADSVSVNIESAEGTQEVRAQWLIACDGGRSTVREQLGLRMEGTQYEGRYVIVDIVQKTKRDVERLAWFDPPSNPGST
ILMHRQPDDVWRIDYQIRDDEDPIEAVKPENVLPRVQSHLDMIGETEPWEPLWISIYNAKCLTLDAYRHGRVLFAGDAAH
LVPIFGVRGLNSGLDDAGNLAWKLAWVIQGRAGASLLDSYSTERVHATRQNIAHGAKSTEFMAPPNFAFELMRQATLRLA
LDEPGVRSLINPRQSAPIAYADSALNGPSDFGGECAAAAPGMPAPEARVDRGHLTASFGHRFTLLWFGDSVPGDIAAMAQ
AHAAGVQLLAINPAGSTAREGMLVDVDGQAFQRYGAQPGTLYVIRPDGYVLARWRTPQPDQIRTVLAPFLQTPSDGARHA
S
>Mature_560_residues
TDRSAPAPAPASAAPPVPPVADARPWPSEVPVLIAGGGPVGLALSALLARQGIASLVIEADGGYCAGSRAICMSRRSLEI
LGWVGADQATVDKGLPWVGGRSYYRDAEVLHFRMPSEPGERFAPMVNIQQYYLEAFAHEAALACGTLADVRFNARVITVR
QDADSVSVNIESAEGTQEVRAQWLIACDGGRSTVREQLGLRMEGTQYEGRYVIVDIVQKTKRDVERLAWFDPPSNPGSTI
LMHRQPDDVWRIDYQIRDDEDPIEAVKPENVLPRVQSHLDMIGETEPWEPLWISIYNAKCLTLDAYRHGRVLFAGDAAHL
VPIFGVRGLNSGLDDAGNLAWKLAWVIQGRAGASLLDSYSTERVHATRQNIAHGAKSTEFMAPPNFAFELMRQATLRLAL
DEPGVRSLINPRQSAPIAYADSALNGPSDFGGECAAAAPGMPAPEARVDRGHLTASFGHRFTLLWFGDSVPGDIAAMAQA
HAAGVQLLAINPAGSTAREGMLVDVDGQAFQRYGAQPGTLYVIRPDGYVLARWRTPQPDQIRTVLAPFLQTPSDGARHAS

Specific function: Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3- hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI) [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pheA/tfdB FAD monooxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786543, Length=532, Percent_Identity=28.0075187969925, Blast_Score=144, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 60735; Mature: 60604

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRSAPAPAPASAAPPVPPVADARPWPSEVPVLIAGGGPVGLALSALLARQGIASLVIE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCEEEEEE
ADGGYCAGSRAICMSRRSLEILGWVGADQATVDKGLPWVGGRSYYRDAEVLHFRMPSEPG
CCCCEECCCCCEEECCCCEEEEEEECCCHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCC
ERFAPMVNIQQYYLEAFAHEAALACGTLADVRFNARVITVRQDADSVSVNIESAEGTQEV
CHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECEEEEEEECCCCEEEEEEECCCCCHHH
RAQWLIACDGGRSTVREQLGLRMEGTQYEGRYVIVDIVQKTKRDVERLAWFDPPSNPGST
CEEEEEEECCCHHHHHHHHCCEECCCEECCCEEEEEHHHHHHHHHHHHCCCCCCCCCCCE
ILMHRQPDDVWRIDYQIRDDEDPIEAVKPENVLPRVQSHLDMIGETEPWEPLWISIYNAK
EEEECCCCCEEEEEEEEECCCCCHHHCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCE
CLTLDAYRHGRVLFAGDAAHLVPIFGVRGLNSGLDDAGNLAWKLAWVIQGRAGASLLDSY
EEEEECCCCCEEEEECCCCCEEEEHCCCCCCCCCCCCCCEEEEEEEEEECCCCHHHHHHC
STERVHATRQNIAHGAKSTEFMAPPNFAFELMRQATLRLALDEPGVRSLINPRQSAPIAY
CHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHEEEECCCCHHHHCCCCCCCCEEE
ADSALNGPSDFGGECAAAAPGMPAPEARVDRGHLTASFGHRFTLLWFGDSVPGDIAAMAQ
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEEEECCCCCCHHHHHHH
AHAAGVQLLAINPAGSTAREGMLVDVDGQAFQRYGAQPGTLYVIRPDGYVLARWRTPQPD
HHHCCEEEEEECCCCCHHHCCEEEEECHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCH
QIRTVLAPFLQTPSDGARHAS
HHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TDRSAPAPAPASAAPPVPPVADARPWPSEVPVLIAGGGPVGLALSALLARQGIASLVIE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCEEEEEE
ADGGYCAGSRAICMSRRSLEILGWVGADQATVDKGLPWVGGRSYYRDAEVLHFRMPSEPG
CCCCEECCCCCEEECCCCEEEEEEECCCHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCC
ERFAPMVNIQQYYLEAFAHEAALACGTLADVRFNARVITVRQDADSVSVNIESAEGTQEV
CHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECEEEEEEECCCCEEEEEEECCCCCHHH
RAQWLIACDGGRSTVREQLGLRMEGTQYEGRYVIVDIVQKTKRDVERLAWFDPPSNPGST
CEEEEEEECCCHHHHHHHHCCEECCCEECCCEEEEEHHHHHHHHHHHHCCCCCCCCCCCE
ILMHRQPDDVWRIDYQIRDDEDPIEAVKPENVLPRVQSHLDMIGETEPWEPLWISIYNAK
EEEECCCCCEEEEEEEEECCCCCHHHCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCE
CLTLDAYRHGRVLFAGDAAHLVPIFGVRGLNSGLDDAGNLAWKLAWVIQGRAGASLLDSY
EEEEECCCCCEEEEECCCCCEEEEHCCCCCCCCCCCCCCEEEEEEEEEECCCCHHHHHHC
STERVHATRQNIAHGAKSTEFMAPPNFAFELMRQATLRLALDEPGVRSLINPRQSAPIAY
CHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHEEEECCCCHHHHCCCCCCCCEEE
ADSALNGPSDFGGECAAAAPGMPAPEARVDRGHLTASFGHRFTLLWFGDSVPGDIAAMAQ
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEEEECCCCCCHHHHHHH
AHAAGVQLLAINPAGSTAREGMLVDVDGQAFQRYGAQPGTLYVIRPDGYVLARWRTPQPD
HHHCCEEEEEECCCCCHHHCCEEEEECHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCH
QIRTVLAPFLQTPSDGARHAS
HHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA