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The map label for this gene is uxaA [H]

Identifier: 73539121

GI number: 73539121

Start: 2058281

End: 2059435

Strand: Direct

Name: uxaA [H]

Synonym: Reut_B5298

Alternate gene names: 73539121

Gene position: 2058281-2059435 (Clockwise)

Preceding gene: 73539120

Following gene: 73539122

Centisome position: 75.5

GC content: 65.71

Gene sequence:

>1155_bases
ATGGCAACCACCTTTCTCGGATATCCGCGCGAAAACGGCGCGGTCGGCGTGCGCAACTGGGTCGCCGTCGTTTCGGTCAT
GGATAACTGCAACCCTGTGACGCGCACCATTGCGCGCACCGTGGGCGGCTGCATCCCGGTCACTACGCTGTTCGTGCGCG
GCCAGTTCGGCGCCGACCTGGATTTCGCCTTCGAGCAGCTGGCCGGGCTGGGCCGCAACCCCAATATCGCCTCGGTACTG
CTGGTTGGCCTGGAGCCCTCGTCCACGGAAGAAGTGGCGCGCCGCATCCAGGCTGCCGGCAAACCGGTCGAACGCGTGCA
CCTGCAGCCCAACGGCACTGTTGACTGCATCGCCGAAGGCACGCGCAAGGCGGCCCGCCTGTCGCTGGCCGCGTCGCGTG
CGCGCCGCGTGCCGTGCCCGGTATCGTCGCTGGTAATCGGTGTGGAATGCGGCGGATCGGATACCACCTCGGGCCTGAGC
TGCAATCCGGTCATCGGACGCATGGCGGATATGGTGATCGCCGAAGGCGGCACTGTCATCATCTCGGAGACCTCGGAATT
CATTGGCGCCGATCACCTGTTTGCCGAACGCGCCGCTGACGGCCGCGTGCGCGAGGCCTTCGTCACTGCGGTGCGCAATA
TGGAAAACCTCGCGATCTCGCGCGGCGTCGACATGCGCGAAGACCAGCCTTCGCCCGACAACAAGCGCGGCGGTCTGACC
ACCGTCGAGGAAAAAGCGCTGGGCGCCATGGCCAAGGCCGGCAGCACGCCACTGGTGGGCGTGCTGCGCTACGGCGAGGC
GCCGCGCAAGCCGGGGCTGCATTTCATGGACGCACCGGCCGCGGCAGTGGAAAATCTGACTGCGCTTGCCGCCGGCGGGT
GCCAGCTCACGTTTTTCGGCACGGGCGTGGGCAACCCGATCGGCAGCATGGTGGCACCGACCGTCAAGGTGTGCGGCAAC
GTCAATACGCTGCAGACCATGGCCGACAACATAGATTTCGACGTGAGCGGCGTCCTGCAGCACGGAGAGAAGATCTCCGA
CCTTGGCGAGCAGCTGTATGCCTATGCGATGGATATCGCATCGGGCACGCAGCTGACCAGCGAGGTGCTCGATGTCCGGG
AGACCGCGATCAGTCGATTCGCACTGAGCCTCTGA

Upstream 100 bases:

>100_bases
TCGGCCGCGCCAGCCATATGATCCGGGCCGGCGAACACATGCACGTTCACAACATCGAATCGGCGCGCGCGCGCGGCGAC
CTGCACAAGGGCTGACACAG

Downstream 100 bases:

>100_bases
GCAACCATGACCAAACTGAACAGCGTCTCCGACGCGATCATCCGCTCCATCGAATCCGGCGCCCTGCGCGAGGGCGACCG
CCTGCCGTCAGAGGCAGAGC

Product: Altronate dehydratase

Products: NA

Alternate protein names: Altronic acid hydratase [H]

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MATTFLGYPRENGAVGVRNWVAVVSVMDNCNPVTRTIARTVGGCIPVTTLFVRGQFGADLDFAFEQLAGLGRNPNIASVL
LVGLEPSSTEEVARRIQAAGKPVERVHLQPNGTVDCIAEGTRKAARLSLAASRARRVPCPVSSLVIGVECGGSDTTSGLS
CNPVIGRMADMVIAEGGTVIISETSEFIGADHLFAERAADGRVREAFVTAVRNMENLAISRGVDMREDQPSPDNKRGGLT
TVEEKALGAMAKAGSTPLVGVLRYGEAPRKPGLHFMDAPAAAVENLTALAAGGCQLTFFGTGVGNPIGSMVAPTVKVCGN
VNTLQTMADNIDFDVSGVLQHGEKISDLGEQLYAYAMDIASGTQLTSEVLDVRETAISRFALSL

Sequences:

>Translated_384_residues
MATTFLGYPRENGAVGVRNWVAVVSVMDNCNPVTRTIARTVGGCIPVTTLFVRGQFGADLDFAFEQLAGLGRNPNIASVL
LVGLEPSSTEEVARRIQAAGKPVERVHLQPNGTVDCIAEGTRKAARLSLAASRARRVPCPVSSLVIGVECGGSDTTSGLS
CNPVIGRMADMVIAEGGTVIISETSEFIGADHLFAERAADGRVREAFVTAVRNMENLAISRGVDMREDQPSPDNKRGGLT
TVEEKALGAMAKAGSTPLVGVLRYGEAPRKPGLHFMDAPAAAVENLTALAAGGCQLTFFGTGVGNPIGSMVAPTVKVCGN
VNTLQTMADNIDFDVSGVLQHGEKISDLGEQLYAYAMDIASGTQLTSEVLDVRETAISRFALSL
>Mature_383_residues
ATTFLGYPRENGAVGVRNWVAVVSVMDNCNPVTRTIARTVGGCIPVTTLFVRGQFGADLDFAFEQLAGLGRNPNIASVLL
VGLEPSSTEEVARRIQAAGKPVERVHLQPNGTVDCIAEGTRKAARLSLAASRARRVPCPVSSLVIGVECGGSDTTSGLSC
NPVIGRMADMVIAEGGTVIISETSEFIGADHLFAERAADGRVREAFVTAVRNMENLAISRGVDMREDQPSPDNKRGGLTT
VEEKALGAMAKAGSTPLVGVLRYGEAPRKPGLHFMDAPAAAVENLTALAAGGCQLTFFGTGVGNPIGSMVAPTVKVCGNV
NTLQTMADNIDFDVSGVLQHGEKISDLGEQLYAYAMDIASGTQLTSEVLDVRETAISRFALSL

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG2721

COG function: function code G; Altronate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uxaA family [H]

Homologues:

Organism=Escherichia coli, GI1789475, Length=388, Percent_Identity=35.3092783505155, Blast_Score=211, Evalue=5e-56,
Organism=Escherichia coli, GI1789516, Length=388, Percent_Identity=29.639175257732, Blast_Score=150, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007392
- InterPro:   IPR013974 [H]

Pfam domain/function: PF04295 GD_AH_C; PF08666 SAF [H]

EC number: =4.2.1.7 [H]

Molecular weight: Translated: 40237; Mature: 40106

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTFLGYPRENGAVGVRNWVAVVSVMDNCNPVTRTIARTVGGCIPVTTLFVRGQFGADL
CCCCEECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHEEECCCCCCH
DFAFEQLAGLGRNPNIASVLLVGLEPSSTEEVARRIQAAGKPVERVHLQPNGTVDCIAEG
HHHHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHH
TRKAARLSLAASRARRVPCPVSSLVIGVECGGSDTTSGLSCNPVIGRMADMVIAEGGTVI
HHHHHHHHHHHHHHCCCCCCHHHEEEEEEECCCCCCCCCCCCHHHHHHHHHHEECCCEEE
ISETSEFIGADHLFAERAADGRVREAFVTAVRNMENLAISRGVDMREDQPSPDNKRGGLT
EECCHHHHCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
TVEEKALGAMAKAGSTPLVGVLRYGEAPRKPGLHFMDAPAAAVENLTALAAGGCQLTFFG
HHHHHHHHHHHHCCCCCEEHHEECCCCCCCCCCEEECCCHHHHHHHHHHCCCCEEEEEEE
TGVGNPIGSMVAPTVKVCGNVNTLQTMADNIDFDVSGVLQHGEKISDLGEQLYAYAMDIA
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHC
SGTQLTSEVLDVRETAISRFALSL
CCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATTFLGYPRENGAVGVRNWVAVVSVMDNCNPVTRTIARTVGGCIPVTTLFVRGQFGADL
CCCEECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHEEECCCCCCH
DFAFEQLAGLGRNPNIASVLLVGLEPSSTEEVARRIQAAGKPVERVHLQPNGTVDCIAEG
HHHHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHH
TRKAARLSLAASRARRVPCPVSSLVIGVECGGSDTTSGLSCNPVIGRMADMVIAEGGTVI
HHHHHHHHHHHHHHCCCCCCHHHEEEEEEECCCCCCCCCCCCHHHHHHHHHHEECCCEEE
ISETSEFIGADHLFAERAADGRVREAFVTAVRNMENLAISRGVDMREDQPSPDNKRGGLT
EECCHHHHCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
TVEEKALGAMAKAGSTPLVGVLRYGEAPRKPGLHFMDAPAAAVENLTALAAGGCQLTFFG
HHHHHHHHHHHHCCCCCEEHHEECCCCCCCCCCEEECCCHHHHHHHHHHCCCCEEEEEEE
TGVGNPIGSMVAPTVKVCGNVNTLQTMADNIDFDVSGVLQHGEKISDLGEQLYAYAMDIA
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHC
SGTQLTSEVLDVRETAISRFALSL
CCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 3038546 [H]