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The map label for this gene is fadB1 [H]

Identifier: 73539106

GI number: 73539106

Start: 2043481

End: 2044272

Strand: Reverse

Name: fadB1 [H]

Synonym: Reut_B5283

Alternate gene names: 73539106

Gene position: 2044272-2043481 (Counterclockwise)

Preceding gene: 73539107

Following gene: 73539105

Centisome position: 74.99

GC content: 64.14

Gene sequence:

>792_bases
ATGAGTCAGGAAGTCGTGAGTTATGAACTCGATGGCGACGTTGCCATGATCGGTCTCAACCGCCCGGCCAAGCGTAATGC
CTTCAACGACGAACTGCATAAGCAGTTGCATGCGGCAGTGATGCGCGCGGGTGAAGAGGCCAGGTGCGGCGTGCTGTTCG
GTCATGGGGAGTGCTTCAGCGGTGGGCTGGATCTCGCCTACGCCGCGGCGATGTGGGAAAGCGGCAAGGAGCACAAGCTG
CCGTATCCCCGCAATTACGACACTGAGCTGATCGCTCGGGGCAGGATCCCGTTCGTCTCTGCCTTGCATGGCGCCACCAT
TGGTGGCGGCTTCGAGGCCGCGGCCAGCACCCATATTCGGGTCGCCGACGAAACGACGTTCTTCGCCCTGCCTGAGGGCC
AGCGTGGCATCTTCGTCGGCGGCGCCGGCTCGGTGCGGATCAGCCGGCTGATCGGCACCGCCCTCATGACGGACCTGATG
TTGACGGGACGCGTGCTGAACGCCGAGGAGGCGCTGCGCTTCAACGCGGTGCAGTATGTGGTGCCCAAGGGGCAAGCGCT
GGAGAAGGCCGTCGCATTGGCCCGGCGCATCTGCGCCAACGCGCCGCTGACCAATTTCGCCATCACCAATGCCTTGCCGC
GCATCGCGGATATGTCGTACGACGATGGCATCTTCGTCGAGCGGCTGGTCAGCGAATACACCCTCAGCCCCGAAACGACC
GCGCGTCTGGGCGAGTTCCTGAACAAGAAGGCGGCGCCCATCAAGGCGCCGGGAGGGGGAGAGACGCTGTGA

Upstream 100 bases:

>100_bases
GTTGCTCAAACGAAATTTGCTCGCCCACATCGATGCAGTGGCGCAGGGATGACCGGGCTGTTGCCGTCGTGAATTGAACG
AAACATCGAAGGAGAAAGAG

Downstream 100 bases:

>100_bases
AGTGCCTGCGCGAATCGGCGATCGTCGCTTATGCCGAAACCAAGGTCATGGAGAAAAGCGACCGCGACGTCTGGGAGCTT
GATGCCGAAGTCCTCGAAGC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MSQEVVSYELDGDVAMIGLNRPAKRNAFNDELHKQLHAAVMRAGEEARCGVLFGHGECFSGGLDLAYAAAMWESGKEHKL
PYPRNYDTELIARGRIPFVSALHGATIGGGFEAAASTHIRVADETTFFALPEGQRGIFVGGAGSVRISRLIGTALMTDLM
LTGRVLNAEEALRFNAVQYVVPKGQALEKAVALARRICANAPLTNFAITNALPRIADMSYDDGIFVERLVSEYTLSPETT
ARLGEFLNKKAAPIKAPGGGETL

Sequences:

>Translated_263_residues
MSQEVVSYELDGDVAMIGLNRPAKRNAFNDELHKQLHAAVMRAGEEARCGVLFGHGECFSGGLDLAYAAAMWESGKEHKL
PYPRNYDTELIARGRIPFVSALHGATIGGGFEAAASTHIRVADETTFFALPEGQRGIFVGGAGSVRISRLIGTALMTDLM
LTGRVLNAEEALRFNAVQYVVPKGQALEKAVALARRICANAPLTNFAITNALPRIADMSYDDGIFVERLVSEYTLSPETT
ARLGEFLNKKAAPIKAPGGGETL
>Mature_262_residues
SQEVVSYELDGDVAMIGLNRPAKRNAFNDELHKQLHAAVMRAGEEARCGVLFGHGECFSGGLDLAYAAAMWESGKEHKLP
YPRNYDTELIARGRIPFVSALHGATIGGGFEAAASTHIRVADETTFFALPEGQRGIFVGGAGSVRISRLIGTALMTDLML
TGRVLNAEEALRFNAVQYVVPKGQALEKAVALARRICANAPLTNFAITNALPRIADMSYDDGIFVERLVSEYTLSPETTA
RLGEFLNKKAAPIKAPGGGETL

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI20127408, Length=190, Percent_Identity=31.0526315789474, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI70995211, Length=204, Percent_Identity=29.9019607843137, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI68989263, Length=229, Percent_Identity=28.3842794759825, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI31542718, Length=201, Percent_Identity=25.8706467661692, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1787659, Length=265, Percent_Identity=31.3207547169811, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI221142681, Length=215, Percent_Identity=30.2325581395349, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788682, Length=205, Percent_Identity=32.6829268292683, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788597, Length=219, Percent_Identity=26.9406392694064, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560910, Length=208, Percent_Identity=28.3653846153846, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI25145438, Length=226, Percent_Identity=29.646017699115, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17536985, Length=256, Percent_Identity=25, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17540714, Length=196, Percent_Identity=27.5510204081633, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17554946, Length=220, Percent_Identity=26.8181818181818, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17558304, Length=179, Percent_Identity=27.9329608938547, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508951, Length=161, Percent_Identity=29.1925465838509, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25144276, Length=161, Percent_Identity=29.1925465838509, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508953, Length=161, Percent_Identity=29.1925465838509, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20129971, Length=240, Percent_Identity=27.9166666666667, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24653477, Length=240, Percent_Identity=27.9166666666667, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24653139, Length=244, Percent_Identity=29.5081967213115, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI21357171, Length=189, Percent_Identity=30.6878306878307, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24650670, Length=195, Percent_Identity=30.2564102564103, Blast_Score=78, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 28255; Mature: 28123

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQEVVSYELDGDVAMIGLNRPAKRNAFNDELHKQLHAAVMRAGEEARCGVLFGHGECFS
CCCCEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCC
GGLDLAYAAAMWESGKEHKLPYPRNYDTELIARGRIPFVSALHGATIGGGFEAAASTHIR
CCHHHHHHHHHHHCCCCCCCCCCCCCCHHEEECCCCCHHHHHCCCCCCCCCHHHCCCEEE
VADETTFFALPEGQRGIFVGGAGSVRISRLIGTALMTDLMLTGRVLNAEEALRFNAVQYV
EECCCEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEE
VPKGQALEKAVALARRICANAPLTNFAITNALPRIADMSYDDGIFVERLVSEYTLSPETT
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHH
ARLGEFLNKKAAPIKAPGGGETL
HHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SQEVVSYELDGDVAMIGLNRPAKRNAFNDELHKQLHAAVMRAGEEARCGVLFGHGECFS
CCCEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCC
GGLDLAYAAAMWESGKEHKLPYPRNYDTELIARGRIPFVSALHGATIGGGFEAAASTHIR
CCHHHHHHHHHHHCCCCCCCCCCCCCCHHEEECCCCCHHHHHCCCCCCCCCHHHCCCEEE
VADETTFFALPEGQRGIFVGGAGSVRISRLIGTALMTDLMLTGRVLNAEEALRFNAVQYV
EECCCEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEE
VPKGQALEKAVALARRICANAPLTNFAITNALPRIADMSYDDGIFVERLVSEYTLSPETT
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHH
ARLGEFLNKKAAPIKAPGGGETL
HHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7751302; 11481430 [H]