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The map label for this gene is cmpR [H]

Identifier: 73539103

GI number: 73539103

Start: 2040820

End: 2041776

Strand: Direct

Name: cmpR [H]

Synonym: Reut_B5280

Alternate gene names: 73539103

Gene position: 2040820-2041776 (Clockwise)

Preceding gene: 73539102

Following gene: 73539120

Centisome position: 74.86

GC content: 61.55

Gene sequence:

>957_bases
ATGGCAAGCCCAATCAACGAAAGCCGCATAGGCTATCTGTATGAAGCCGTACGAAGCGGCACGGTACGCGCGGCGGCCGA
TTATCTTGATGTGGCACCCTCGGCCGTCAGCAGGCAGATTGCGCTGCTGGAAGAGGAGCTCGCCATCGCTCTGGTGGAAC
GCAACAAGCGCGGCGTCCGGCCGACCGAAGCGGGTGCCCTGCTTATCGAGTACTTCCGGCAGCAACGTTCCCATCAGGGC
GACCTGGTTGCCAAGCTCCAGGAGATCCGGGGACTTCGCCGCGGCACGATCGTTGTCGTGATGGGCGAAGGCTTTGCCTC
CACCATGGTCGGCGGCCCTATCAAGCAGTTCTGCGAAGCGTACCCAGAGATTTCGATCACGATGGACCTTTGCAGCACCA
ACGAGGTCATGCGGAGGGTGTCGGAAGATGAAGCAGACATAGGCCTGGTCTTCAACCCGTCATCCGACAGCAAAATCGTG
AGCCGCGCGGGATCGCGCCAGCCGATGCATGCCATCGTCTCGCCGGCATTCCCGCTGGTTGGCAAGGTGAAATCGGTAAC
GCTTCAAGATCTTATGCCGTACCCGATGGCCCTGACACATCCCGAACACGGTACGCGGCGGCTGGTGGACGCTGCCATGC
TGCTCGACAAGGTCAGGCTCACCCCTGCCATCACGACCAATTCGGTAAATGTCCTGAAGCTCTTTGCAAAGAGCAACCTG
GGATTCACGCTGCTCGCGCCCATCGCGATTGCACCGGAACTGGCGGCAGGCGAGCTGGTGGCCCTTCCCGTGGACAATCG
CCTGCTCGAGAGTTCCGAGGCCCATCTCGTCACGCGTGCCGGCCGCCAGCTCTCTCCGGCGGCCAACCGGTTGCTGAATC
GACTGAAGGCGCAGATACACAAGTACGATGAGTACGGCGCGGAGTCCGGCGGGCAGGCTTCATTGGCGACGCAGTAG

Upstream 100 bases:

>100_bases
AACCGCCGTCCCGTCCCGGCATGCGATTGCGCTCTCGCGATCAGGAGTGCGAGAATCCGCTATTGGCCAGGGACGGCGCT
GCTCGTATCGGGAAAACGGA

Downstream 100 bases:

>100_bases
TGCGACTGTTCCCCGCGGTCACGGCGTACGGGCGAGCTTGCCCGCCACGTTGGAGGCATCGGCGGTCATCGCTGCTCTAC
CGCTCCGGTTCAAACATCAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MASPINESRIGYLYEAVRSGTVRAAADYLDVAPSAVSRQIALLEEELAIALVERNKRGVRPTEAGALLIEYFRQQRSHQG
DLVAKLQEIRGLRRGTIVVVMGEGFASTMVGGPIKQFCEAYPEISITMDLCSTNEVMRRVSEDEADIGLVFNPSSDSKIV
SRAGSRQPMHAIVSPAFPLVGKVKSVTLQDLMPYPMALTHPEHGTRRLVDAAMLLDKVRLTPAITTNSVNVLKLFAKSNL
GFTLLAPIAIAPELAAGELVALPVDNRLLESSEAHLVTRAGRQLSPAANRLLNRLKAQIHKYDEYGAESGGQASLATQ

Sequences:

>Translated_318_residues
MASPINESRIGYLYEAVRSGTVRAAADYLDVAPSAVSRQIALLEEELAIALVERNKRGVRPTEAGALLIEYFRQQRSHQG
DLVAKLQEIRGLRRGTIVVVMGEGFASTMVGGPIKQFCEAYPEISITMDLCSTNEVMRRVSEDEADIGLVFNPSSDSKIV
SRAGSRQPMHAIVSPAFPLVGKVKSVTLQDLMPYPMALTHPEHGTRRLVDAAMLLDKVRLTPAITTNSVNVLKLFAKSNL
GFTLLAPIAIAPELAAGELVALPVDNRLLESSEAHLVTRAGRQLSPAANRLLNRLKAQIHKYDEYGAESGGQASLATQ
>Mature_317_residues
ASPINESRIGYLYEAVRSGTVRAAADYLDVAPSAVSRQIALLEEELAIALVERNKRGVRPTEAGALLIEYFRQQRSHQGD
LVAKLQEIRGLRRGTIVVVMGEGFASTMVGGPIKQFCEAYPEISITMDLCSTNEVMRRVSEDEADIGLVFNPSSDSKIVS
RAGSRQPMHAIVSPAFPLVGKVKSVTLQDLMPYPMALTHPEHGTRRLVDAAMLLDKVRLTPAITTNSVNVLKLFAKSNLG
FTLLAPIAIAPELAAGELVALPVDNRLLESSEAHLVTRAGRQLSPAANRLLNRLKAQIHKYDEYGAESGGQASLATQ

Specific function: Activates transcription of the cmpABCD operon under carbon dioxide-limited conditions. Specifically binds to the cmpR- cmpA intergenic region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=248, Percent_Identity=27.8225806451613, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1788481, Length=284, Percent_Identity=26.056338028169, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI145693105, Length=274, Percent_Identity=23.3576642335766, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787530, Length=246, Percent_Identity=26.0162601626016, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786401, Length=257, Percent_Identity=28.7937743190661, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1789440, Length=252, Percent_Identity=23.8095238095238, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI87082132, Length=296, Percent_Identity=21.6216216216216, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787601, Length=305, Percent_Identity=22.6229508196721, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1788297, Length=162, Percent_Identity=28.3950617283951, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34467; Mature: 34336

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASPINESRIGYLYEAVRSGTVRAAADYLDVAPSAVSRQIALLEEELAIALVERNKRGVR
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PTEAGALLIEYFRQQRSHQGDLVAKLQEIRGLRRGTIVVVMGEGFASTMVGGPIKQFCEA
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEECCCHHHHHCCCHHHHHHHH
YPEISITMDLCSTNEVMRRVSEDEADIGLVFNPSSDSKIVSRAGSRQPMHAIVSPAFPLV
CCCEEEEEEHHCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHCCCCCCHHHHHCCCHHHH
GKVKSVTLQDLMPYPMALTHPEHGTRRLVDAAMLLDKVRLTPAITTNSVNVLKLFAKSNL
HHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCEEECCCHHHHEEEHHCCC
GFTLLAPIAIAPELAAGELVALPVDNRLLESSEAHLVTRAGRQLSPAANRLLNRLKAQIH
CEEEEHHHHHCCCCCCCCEEEECCCCHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHH
KYDEYGAESGGQASLATQ
HHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
ASPINESRIGYLYEAVRSGTVRAAADYLDVAPSAVSRQIALLEEELAIALVERNKRGVR
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PTEAGALLIEYFRQQRSHQGDLVAKLQEIRGLRRGTIVVVMGEGFASTMVGGPIKQFCEA
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEECCCHHHHHCCCHHHHHHHH
YPEISITMDLCSTNEVMRRVSEDEADIGLVFNPSSDSKIVSRAGSRQPMHAIVSPAFPLV
CCCEEEEEEHHCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHCCCCCCHHHHHCCCHHHH
GKVKSVTLQDLMPYPMALTHPEHGTRRLVDAAMLLDKVRLTPAITTNSVNVLKLFAKSNL
HHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCEEECCCHHHHEEEHHCCC
GFTLLAPIAIAPELAAGELVALPVDNRLLESSEAHLVTRAGRQLSPAANRLLNRLKAQIH
CEEEEHHHHHCCCCCCCCEEEECCCCHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHH
KYDEYGAESGGQASLATQ
HHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]