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The map label for this gene is yajO [H]

Identifier: 73539056

GI number: 73539056

Start: 1981946

End: 1982995

Strand: Reverse

Name: yajO [H]

Synonym: Reut_B5233

Alternate gene names: 73539056

Gene position: 1982995-1981946 (Counterclockwise)

Preceding gene: 73539061

Following gene: 73539055

Centisome position: 72.74

GC content: 66.29

Gene sequence:

>1050_bases
ATGCCTGACATCGCCACGCACGCCGTGCCATATCGACGCCTTGGTACCAGCAACCTGAAGGTCTCCGCGCTGTGCCTCGG
GACCATGATGTTCGCCGACCAGACCGACGAAGCCGAAGCGGCACGCATCGTCGCCAGCGCGCGCGAGCACGGCGTGAACT
TCATCGATACCGCAGACGTCTACAGCAAGGGCGCGTCCGAACAGATGGTCGGTCGCCTGCTAACGGGCGATCGGCACGAC
TGGGTGCTCGCGACCAAGCTCGGCAACCCCATGCAGGCGGGACCAAACCATTCGCACTATTCGCGCGTCTGGATCCTGCA
CGAAACCGAGGAGAGCCTGCGCCGCCTGGCCACCGACTACATCGACATCCTGTATCTGCACCGCGACTACGCGGGCGAGA
ATCTCGAGGAAGCCGTACGCGCGATGGGCGATCTCGTGCGCGCGGGCAAGATCCGCTACTGGGCAGTCTCGAACTTCCGC
GGCTGGCGCATTGCCGAGATTGCGCGGCTGTGCGACCAGCTCGGCGTGCCGCGCCCCGTGGCCTGCCAGCCGTACTACAA
CCTGCTCAACCGCATGCCGGAAGTCGAGATCCTGCCTGCCTGCGAACACTATGGCCTGGGCGTCGTGCCGTACAGCCCGA
TCGCGCGCGGCGTACTGACGGGCAAGTATCAGCCGGGCCAGGCGCCGGCCAGCGGCACGCGCGCCGGCCGCGCCGACCGC
CGCATGATGCAGACCGAGTTCCGCGAGGAATCGCTCATCATCGCGCAACAGCTCAAGGTGCATGCCGAGGCGCGCGGGCT
CACGCCGGGCCAGTTCGCGACCGCCTGGGTGCTGGCCAATCCGATCATCACGTCGGTGATTGCAGGCCCGCGTACGCTGT
CGCAGTTTGAAGACTACTTCGGCGCGATGAACGTTGTCATTTCGCCGGAAGAGGAAGCCATGGTCGATGCGCTCGTCACG
CCGGGCCATGCGTCGACGCATGGCTATAACGATCCGAACTACCCGTTTGGCGGCCGTCCGGTACGCGTGGCGGCACCGCC
GGCGGCCTGA

Upstream 100 bases:

>100_bases
CTCTGCGCGATTCGCGCATTCGCGGCAAAATGCAGATCGGCCGCGCTGCCGGCAATATGAACATTACGGACATTGATTCT
TGCAAAACAGGAAAACCGCC

Downstream 100 bases:

>100_bases
GGCGCCGGCAAGTGGACAATGCGTGGCTCTTGCCGCCGATGTTTTGTGGCAACAACCGCGTAAGCCCTCAAGCTGTCCCT
GCGCGTCGCGCGCGTTCCTA

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MPDIATHAVPYRRLGTSNLKVSALCLGTMMFADQTDEAEAARIVASAREHGVNFIDTADVYSKGASEQMVGRLLTGDRHD
WVLATKLGNPMQAGPNHSHYSRVWILHETEESLRRLATDYIDILYLHRDYAGENLEEAVRAMGDLVRAGKIRYWAVSNFR
GWRIAEIARLCDQLGVPRPVACQPYYNLLNRMPEVEILPACEHYGLGVVPYSPIARGVLTGKYQPGQAPASGTRAGRADR
RMMQTEFREESLIIAQQLKVHAEARGLTPGQFATAWVLANPIITSVIAGPRTLSQFEDYFGAMNVVISPEEEAMVDALVT
PGHASTHGYNDPNYPFGGRPVRVAAPPAA

Sequences:

>Translated_349_residues
MPDIATHAVPYRRLGTSNLKVSALCLGTMMFADQTDEAEAARIVASAREHGVNFIDTADVYSKGASEQMVGRLLTGDRHD
WVLATKLGNPMQAGPNHSHYSRVWILHETEESLRRLATDYIDILYLHRDYAGENLEEAVRAMGDLVRAGKIRYWAVSNFR
GWRIAEIARLCDQLGVPRPVACQPYYNLLNRMPEVEILPACEHYGLGVVPYSPIARGVLTGKYQPGQAPASGTRAGRADR
RMMQTEFREESLIIAQQLKVHAEARGLTPGQFATAWVLANPIITSVIAGPRTLSQFEDYFGAMNVVISPEEEAMVDALVT
PGHASTHGYNDPNYPFGGRPVRVAAPPAA
>Mature_348_residues
PDIATHAVPYRRLGTSNLKVSALCLGTMMFADQTDEAEAARIVASAREHGVNFIDTADVYSKGASEQMVGRLLTGDRHDW
VLATKLGNPMQAGPNHSHYSRVWILHETEESLRRLATDYIDILYLHRDYAGENLEEAVRAMGDLVRAGKIRYWAVSNFRG
WRIAEIARLCDQLGVPRPVACQPYYNLLNRMPEVEILPACEHYGLGVVPYSPIARGVLTGKYQPGQAPASGTRAGRADRR
MMQTEFREESLIIAQQLKVHAEARGLTPGQFATAWVLANPIITSVIAGPRTLSQFEDYFGAMNVVISPEEEAMVDALVTP
GHASTHGYNDPNYPFGGRPVRVAAPPAA

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436966, Length=313, Percent_Identity=33.2268370607029, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI27436962, Length=311, Percent_Identity=33.4405144694534, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI27436964, Length=308, Percent_Identity=33.4415584415584, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI27436971, Length=324, Percent_Identity=32.0987654320988, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI27436969, Length=308, Percent_Identity=31.4935064935065, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI4504825, Length=308, Percent_Identity=31.4935064935065, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI223718702, Length=332, Percent_Identity=29.5180722891566, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI41152114, Length=342, Percent_Identity=29.2397660818713, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI41327764, Length=338, Percent_Identity=30.7692307692308, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI223718708, Length=178, Percent_Identity=30.8988764044944, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI87081735, Length=321, Percent_Identity=36.7601246105919, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI1789375, Length=324, Percent_Identity=31.4814814814815, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1789199, Length=339, Percent_Identity=30.6784660766962, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1788081, Length=271, Percent_Identity=30.6273062730627, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788070, Length=326, Percent_Identity=27.6073619631902, Blast_Score=91, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6325169, Length=329, Percent_Identity=27.355623100304, Blast_Score=128, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6323998, Length=330, Percent_Identity=26.0606060606061, Blast_Score=93, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6319958, Length=300, Percent_Identity=25.6666666666667, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319951, Length=327, Percent_Identity=26.2996941896024, Blast_Score=86, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6322615, Length=212, Percent_Identity=26.8867924528302, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24646159, Length=223, Percent_Identity=28.2511210762332, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI45549126, Length=324, Percent_Identity=22.5308641975309, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24640980, Length=334, Percent_Identity=22.1556886227545, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24646155, Length=318, Percent_Identity=24.8427672955975, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 38440; Mature: 38309

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDIATHAVPYRRLGTSNLKVSALCLGTMMFADQTDEAEAARIVASAREHGVNFIDTADV
CCCCCCCCCCHHHCCCCCCEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEECHHH
YSKGASEQMVGRLLTGDRHDWVLATKLGNPMQAGPNHSHYSRVWILHETEESLRRLATDY
HHCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHH
IDILYLHRDYAGENLEEAVRAMGDLVRAGKIRYWAVSNFRGWRIAEIARLCDQLGVPRPV
HHHHHHECCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCC
ACQPYYNLLNRMPEVEILPACEHYGLGVVPYSPIARGVLTGKYQPGQAPASGTRAGRADR
CCCHHHHHHHCCCCCEEECCHHHCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHH
RMMQTEFREESLIIAQQLKVHAEARGLTPGQFATAWVLANPIITSVIAGPRTLSQFEDYF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
GAMNVVISPEEEAMVDALVTPGHASTHGYNDPNYPFGGRPVRVAAPPAA
CCEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
PDIATHAVPYRRLGTSNLKVSALCLGTMMFADQTDEAEAARIVASAREHGVNFIDTADV
CCCCCCCCCHHHCCCCCCEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEECHHH
YSKGASEQMVGRLLTGDRHDWVLATKLGNPMQAGPNHSHYSRVWILHETEESLRRLATDY
HHCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHH
IDILYLHRDYAGENLEEAVRAMGDLVRAGKIRYWAVSNFRGWRIAEIARLCDQLGVPRPV
HHHHHHECCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCC
ACQPYYNLLNRMPEVEILPACEHYGLGVVPYSPIARGVLTGKYQPGQAPASGTRAGRADR
CCCHHHHHHHCCCCCEEECCHHHCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHH
RMMQTEFREESLIIAQQLKVHAEARGLTPGQFATAWVLANPIITSVIAGPRTLSQFEDYF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
GAMNVVISPEEEAMVDALVTPGHASTHGYNDPNYPFGGRPVRVAAPPAA
CCEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]