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The map label for this gene is apbE [H]

Identifier: 73539035

GI number: 73539035

Start: 1959564

End: 1960571

Strand: Reverse

Name: apbE [H]

Synonym: Reut_B5212

Alternate gene names: 73539035

Gene position: 1960571-1959564 (Counterclockwise)

Preceding gene: 73539036

Following gene: 73539034

Centisome position: 71.92

GC content: 69.25

Gene sequence:

>1008_bases
GTGAACCGCGTCCTGATCCCGCCCACCCTGTCCGCGCCGCCGGTTCCGCCCGGCGCGCAGACTCGCGCGCAGCGCTGGAG
TGGCGAGACCATGGGCACGACGTGGTCGGTCGTGGCCATGCTGGTGCAGGAGGCCGATGCCGACGCGCTGGAGCAGGGCA
TCTGCGCCGTGCTCGACAGCGTGATCGCGCAGATGAGCAATTGGGAGGCCGATTCGGACGTCAGCCGATTCAACCGCGCC
CCCGCGGACACGTGGGTCGCGCTGCCGGCCGACTGCGTGCGCGTGCTTGCGTGCGCGCTGCAGGTCGCGCGCGACAGCGG
TGGCGCCTATGACCCCAGCGCCGGGCCACTGGTCGACCTGTGGGGCTTCGGCCCTGCGCCGCGACGCTGCGCGACGCCGG
CTCCGGACCAGGTCGCTCAGGTCCGGCAGCAATGCGGCTGGGATCGTATCGAACTCGATATCGACGGAGGCTGCGCGCTG
CAGCCGGGTGGCGTATCGCTCGACTTCTGCGCGATTGCCAAGGGCTTTGCGGTAGATGCCGTCGCGCAATACCTCGAGTC
CGAAGGCGTGGCACACCACCTGACCGAAATCGGCGGCGAACTGCGCGGCCACGGCGTCAAGCCGGACGGCTTGCCATGGT
GGGTCCAGCTGGAAACGCCGCCTGATTGTGCAGTCACGGCGCAGGAGCAGACGCTGGTCGCCATGTACGGCCTGTCCGTG
GCAACGTCGGGCGACTACCGGCGCTTCTTCGACAGCGAAGGCCGCCGCTATGCCCACACCATCGACCCGCGCACCGGTTA
TCCAGCCAGCCACGCGCTCGCTTCGGTGACCGTCCTGCACACCGAATGCATGATGGCCGATGCGCTTTCCACTGCCCTGA
CCGTGCTCGGCCCACAGGCCGGCATGGAGCACGCGCGCCGGCATGGCATTGCCGCGCGCTTTCTCGTGCGTACGCCGGGC
GGCTTTGACGAACATCTTTCCCCGGCCTTTGCCGCGATGCTGGCGTGA

Upstream 100 bases:

>100_bases
GACGAGAAGACCTCGGTCAAGGCTGCCAAGACCCGCCGCGCGACCTACGCGGTGACGGTCGAAGTATTGCCGCAATAAGG
CGTCTGAAGGTACCTTCCGC

Downstream 100 bases:

>100_bases
ACCTATTCACCGCATGCTGGCTGGCCGCTGTGGCAGGTGTCTGCGTGGCAATGCTGAGCCCGTCGCGCGCCGGCATGGCA
GCCGGCGTGTTGCTGGCCTA

Product: ApbE-like lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MNRVLIPPTLSAPPVPPGAQTRAQRWSGETMGTTWSVVAMLVQEADADALEQGICAVLDSVIAQMSNWEADSDVSRFNRA
PADTWVALPADCVRVLACALQVARDSGGAYDPSAGPLVDLWGFGPAPRRCATPAPDQVAQVRQQCGWDRIELDIDGGCAL
QPGGVSLDFCAIAKGFAVDAVAQYLESEGVAHHLTEIGGELRGHGVKPDGLPWWVQLETPPDCAVTAQEQTLVAMYGLSV
ATSGDYRRFFDSEGRRYAHTIDPRTGYPASHALASVTVLHTECMMADALSTALTVLGPQAGMEHARRHGIAARFLVRTPG
GFDEHLSPAFAAMLA

Sequences:

>Translated_335_residues
MNRVLIPPTLSAPPVPPGAQTRAQRWSGETMGTTWSVVAMLVQEADADALEQGICAVLDSVIAQMSNWEADSDVSRFNRA
PADTWVALPADCVRVLACALQVARDSGGAYDPSAGPLVDLWGFGPAPRRCATPAPDQVAQVRQQCGWDRIELDIDGGCAL
QPGGVSLDFCAIAKGFAVDAVAQYLESEGVAHHLTEIGGELRGHGVKPDGLPWWVQLETPPDCAVTAQEQTLVAMYGLSV
ATSGDYRRFFDSEGRRYAHTIDPRTGYPASHALASVTVLHTECMMADALSTALTVLGPQAGMEHARRHGIAARFLVRTPG
GFDEHLSPAFAAMLA
>Mature_335_residues
MNRVLIPPTLSAPPVPPGAQTRAQRWSGETMGTTWSVVAMLVQEADADALEQGICAVLDSVIAQMSNWEADSDVSRFNRA
PADTWVALPADCVRVLACALQVARDSGGAYDPSAGPLVDLWGFGPAPRRCATPAPDQVAQVRQQCGWDRIELDIDGGCAL
QPGGVSLDFCAIAKGFAVDAVAQYLESEGVAHHLTEIGGELRGHGVKPDGLPWWVQLETPPDCAVTAQEQTLVAMYGLSV
ATSGDYRRFFDSEGRRYAHTIDPRTGYPASHALASVTVLHTECMMADALSTALTVLGPQAGMEHARRHGIAARFLVRTPG
GFDEHLSPAFAAMLA

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=310, Percent_Identity=31.2903225806452, Blast_Score=180, Evalue=9e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 35644; Mature: 35644

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRVLIPPTLSAPPVPPGAQTRAQRWSGETMGTTWSVVAMLVQEADADALEQGICAVLDS
CCCEECCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHH
VIAQMSNWEADSDVSRFNRAPADTWVALPADCVRVLACALQVARDSGGAYDPSAGPLVDL
HHHHHHCCCCCHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEE
WGFGPAPRRCATPAPDQVAQVRQQCGWDRIELDIDGGCALQPGGVSLDFCAIAKGFAVDA
CCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCEECCCCCCCHHHHHHCCHHHHH
VAQYLESEGVAHHLTEIGGELRGHGVKPDGLPWWVQLETPPDCAVTAQEQTLVAMYGLSV
HHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCEEECCCCEEEEECCCCE
ATSGDYRRFFDSEGRRYAHTIDPRTGYPASHALASVTVLHTECMMADALSTALTVLGPQA
ECCCCHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
GMEHARRHGIAARFLVRTPGGFDEHLSPAFAAMLA
HHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNRVLIPPTLSAPPVPPGAQTRAQRWSGETMGTTWSVVAMLVQEADADALEQGICAVLDS
CCCEECCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHH
VIAQMSNWEADSDVSRFNRAPADTWVALPADCVRVLACALQVARDSGGAYDPSAGPLVDL
HHHHHHCCCCCHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEE
WGFGPAPRRCATPAPDQVAQVRQQCGWDRIELDIDGGCALQPGGVSLDFCAIAKGFAVDA
CCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCEECCCCCCCHHHHHHCCHHHHH
VAQYLESEGVAHHLTEIGGELRGHGVKPDGLPWWVQLETPPDCAVTAQEQTLVAMYGLSV
HHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCEEECCCCEEEEECCCCE
ATSGDYRRFFDSEGRRYAHTIDPRTGYPASHALASVTVLHTECMMADALSTALTVLGPQA
ECCCCHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
GMEHARRHGIAARFLVRTPGGFDEHLSPAFAAMLA
HHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]