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The map label for this gene is yhcS [C]

Identifier: 73539022

GI number: 73539022

Start: 1944569

End: 1945507

Strand: Direct

Name: yhcS [C]

Synonym: Reut_B5199

Alternate gene names: 73539022

Gene position: 1944569-1945507 (Clockwise)

Preceding gene: 73539021

Following gene: 73539023

Centisome position: 71.33

GC content: 67.09

Gene sequence:

>939_bases
ATGAAAACGATCGAATGGAAGGACTGGGAAATTTTCTGCCGCGTGGTGGAAGGCGGCGGCTTTACCCAGGGCGCCGAGCT
GGCTGAGGTGCCAAAGTCCTCGGCCAGCGCGGCGGTGGCCCGGCTGGAGAGCCAGCTTGGGGTGCGTCTGTTTGAACGCA
CCACGCGGCGCGTGCGCGTGACCGAGCGCGGCCAGCGGCTCTACGACCGCGTGGCGCCGCTGTTCGCCGAACTGCACGAG
ATCAACGCCGAGGCCGCCTCCGTCAGCGACGAGGTCAGCGGTGTGCTGCGTATCTCCACCCCCTATGAAGTCGGTTCGCA
GCACCTGTCCGACGGGCTCAGCCGCCTGATGCGCCTGCATCCGCGCCTGCGCGTGCACGTGGATGTCAGCTGGGACCAGC
CCGACCTGATCCGCCATGGCTATGACCTAGCTTTCGTCATGACGAACACGCGGCTTCAGGACACATCGTTCGCGAGCAAG
CGCGTCGTGCTGATCGAGCGCGGCTTCTATGCGGCGCCTGCGCTGATCCGCGACCGCGGCCTGCCGCGTACCCCGCAGGA
CCTGGCCGGCTGGCCCACGCTCGGCAACGCCGACGATCACTTCTGGGAATTCCTGCGCGACGACATCGAAACGGCGCGGC
TGGATGTCGAGCCCCGCATCTGCACGCATAACGCCGAACTGCGCCTGAAGGCCGCCATCGACGGCCTGGGTGTCGCCCGG
CTGTCGCCGCGCTTCGTGCAGGACCAAATCCAGCAAGGGCAGCTTGTACGCGTGCTGCCGGCCTACTCGTCGTCGCCGCT
CAAGGTCTATGTGCTGATGCCGGCGCGAAAGCTGATGCCAGCCAGCGTGCGCGTCTTCCTCGACGTGCTGGAACAGACAC
TGGGCGTGCCGGAGACCAGACGTCCGGCCGCGCGAAAGCGGGAGGCGGTGCAAGCCTGA

Upstream 100 bases:

>100_bases
TCGGCCCCAGCACCATTGTCCACACTGTGGGACAATCCAGCCGCAAGCGCACCCGCTCCCGGACCCATCCGCGAGCGCGC
CACTGACGCCGGGGCACTGC

Downstream 100 bases:

>100_bases
CGCACAACGCAGTCGGCCGCAGATCCGAGGCTATGCTTTTCACATCCAGCGGGAGAAGCGTATGCACAACAGAGCGCGCC
CGGCAGCCACGCAAGCGACG

Product: regulatory protein LysR

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MKTIEWKDWEIFCRVVEGGGFTQGAELAEVPKSSASAAVARLESQLGVRLFERTTRRVRVTERGQRLYDRVAPLFAELHE
INAEAASVSDEVSGVLRISTPYEVGSQHLSDGLSRLMRLHPRLRVHVDVSWDQPDLIRHGYDLAFVMTNTRLQDTSFASK
RVVLIERGFYAAPALIRDRGLPRTPQDLAGWPTLGNADDHFWEFLRDDIETARLDVEPRICTHNAELRLKAAIDGLGVAR
LSPRFVQDQIQQGQLVRVLPAYSSSPLKVYVLMPARKLMPASVRVFLDVLEQTLGVPETRRPAARKREAVQA

Sequences:

>Translated_312_residues
MKTIEWKDWEIFCRVVEGGGFTQGAELAEVPKSSASAAVARLESQLGVRLFERTTRRVRVTERGQRLYDRVAPLFAELHE
INAEAASVSDEVSGVLRISTPYEVGSQHLSDGLSRLMRLHPRLRVHVDVSWDQPDLIRHGYDLAFVMTNTRLQDTSFASK
RVVLIERGFYAAPALIRDRGLPRTPQDLAGWPTLGNADDHFWEFLRDDIETARLDVEPRICTHNAELRLKAAIDGLGVAR
LSPRFVQDQIQQGQLVRVLPAYSSSPLKVYVLMPARKLMPASVRVFLDVLEQTLGVPETRRPAARKREAVQA
>Mature_312_residues
MKTIEWKDWEIFCRVVEGGGFTQGAELAEVPKSSASAAVARLESQLGVRLFERTTRRVRVTERGQRLYDRVAPLFAELHE
INAEAASVSDEVSGVLRISTPYEVGSQHLSDGLSRLMRLHPRLRVHVDVSWDQPDLIRHGYDLAFVMTNTRLQDTSFASK
RVVLIERGFYAAPALIRDRGLPRTPQDLAGWPTLGNADDHFWEFLRDDIETARLDVEPRICTHNAELRLKAAIDGLGVAR
LSPRFVQDQIQQGQLVRVLPAYSSSPLKVYVLMPARKLMPASVRVFLDVLEQTLGVPETRRPAARKREAVQA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=286, Percent_Identity=27.972027972028, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI145693193, Length=286, Percent_Identity=27.972027972028, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI87081978, Length=296, Percent_Identity=29.0540540540541, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1787589, Length=301, Percent_Identity=27.5747508305648, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1789440, Length=300, Percent_Identity=24.3333333333333, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786401, Length=294, Percent_Identity=26.8707482993197, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787128, Length=298, Percent_Identity=24.496644295302, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788481, Length=269, Percent_Identity=28.6245353159851, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789173, Length=240, Percent_Identity=24.5833333333333, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35171; Mature: 35171

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIEWKDWEIFCRVVEGGGFTQGAELAEVPKSSASAAVARLESQLGVRLFERTTRRVRV
CCCCCCCCCEEEEEEECCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEH
TERGQRLYDRVAPLFAELHEINAEAASVSDEVSGVLRISTPYEVGSQHLSDGLSRLMRLH
HHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHCCEEEEECCCHHHHHHHHHHHHHHHHHHC
PRLRVHVDVSWDQPDLIRHGYDLAFVMTNTRLQDTSFASKRVVLIERGFYAAPALIRDRG
CCEEEEEEECCCCCHHHHCCCCEEEEEECCEECCCCCCCCEEEEEECCCCCCCHHHHCCC
LPRTPQDLAGWPTLGNADDHFWEFLRDDIETARLDVEPRICTHNAELRLKAAIDGLGVAR
CCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCEEEEEECCCCCHHH
LSPRFVQDQIQQGQLVRVLPAYSSSPLKVYVLMPARKLMPASVRVFLDVLEQTLGVPETR
CCHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCHHHCHHHHHHHHHHHHHHHCCCCCC
RPAARKREAVQA
CCHHHHHHHCCC
>Mature Secondary Structure
MKTIEWKDWEIFCRVVEGGGFTQGAELAEVPKSSASAAVARLESQLGVRLFERTTRRVRV
CCCCCCCCCEEEEEEECCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEH
TERGQRLYDRVAPLFAELHEINAEAASVSDEVSGVLRISTPYEVGSQHLSDGLSRLMRLH
HHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHCCEEEEECCCHHHHHHHHHHHHHHHHHHC
PRLRVHVDVSWDQPDLIRHGYDLAFVMTNTRLQDTSFASKRVVLIERGFYAAPALIRDRG
CCEEEEEEECCCCCHHHHCCCCEEEEEECCEECCCCCCCCEEEEEECCCCCCCHHHHCCC
LPRTPQDLAGWPTLGNADDHFWEFLRDDIETARLDVEPRICTHNAELRLKAAIDGLGVAR
CCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCEEEEEECCCCCHHH
LSPRFVQDQIQQGQLVRVLPAYSSSPLKVYVLMPARKLMPASVRVFLDVLEQTLGVPETR
CCHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCHHHCHHHHHHHHHHHHHHHCCCCCC
RPAARKREAVQA
CCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]