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The map label for this gene is ttuB [H]

Identifier: 73538947

GI number: 73538947

Start: 1863728

End: 1865014

Strand: Direct

Name: ttuB [H]

Synonym: Reut_B5122

Alternate gene names: 73538947

Gene position: 1863728-1865014 (Clockwise)

Preceding gene: 73538943

Following gene: 73538948

Centisome position: 68.36

GC content: 64.65

Gene sequence:

>1287_bases
ATGATCGCAGTTCCCACCACAAGCGCCGCTGACGACGCCTCCTCGCTTTACAGCAAGATCAACTGGCGATTGCTGCCCTT
CCTGCTGACCTGTTACCTGTTCGCGTACCTGGACCGGGTCAATGTCGGCTTTGCAAAGCTGCAGATGCAAGGCGATCTCG
GCTTCTCCGATGCCGCCTACGGCGTAGGCGCGGGCATTTTCTTCATCGGTTATGTGCTTTTCGAGATACCCAGCAACCTG
CTGCTGCCGCGTGTCGGCGCGCGCAAGACCTTCAGCCGCATCCTGGTGCTGTGGGGCATCACTTCCGCCTGCATGCTCTT
TGTACGCAATGTGCCAATGTTCTACGCCATGCGCTTCCTGCTGGGCGTGTTCGAGGCGGGCTTCGCTCCCGGCATGATCT
ATTACCTCTCGTGCTGGTACGGTCCGCAACGGATGGCGCGCGCCATTGCCATCGTCTTCCTGGCCGGTCCGATCGGCGGC
ATTGTCGGCGGCCCCGTGTCGGCCTGGCTGATGACCTCGCTTGCCGGCACCGCTGGCCTGACAGGCTGGCAGTGGATGTT
CCTGGTCGAGGGGCTGCCTTGCATCCTGCTGGGCATCCTGGCGCTGTCGTTCGTGCCGGACCGGCCCGCCGACGCAGCGT
GGCTGAACGCGGATGAACGGCGCCGGCTGGAAGCGGAACTCCATGTCCCCGGGGCGCACAAGCATTCGTTCATGGCCGTG
GCGAAGGACGCAAGGGTCTACGTGCTGGCGCTCGCCTACTTCTGCATCATCGCCGCGATCTATGCCATCAGCTTCTGGCT
GCCGACCTTCATCAAGGCACAGGGCGTGACCGATACCGTGCAACTCGGCTGGTACTCCGCCATCCCCTATGTGGCCGCCG
CGTTCGGCATGTATTTCATGGGCCGCAGGTCCGACCGCGTGGGCGAGCGGCGCTTCCACAGCGCGCTGCCCGCCCTCGCT
GCCGGGCTGTTGCTGGGTGCCTCGACACTGGCCGATGGCAATCTCGTCCTGACGCTGGCCCTGCTCACGCTTGCCACCAT
GGGCCTGTGGATGGCCTACACCGTGTTCTGGGCCATGCCCGCCGAGTACATCAAGGGCCCGGCGGCGGCCGGCGGCATTG
CGCTGATCAATACCATCGGGTTGTCGGGCGGCTTCTGGGGTCCCGCCATTATCGGGTGGGCCAAGACCGCGACGGGCACC
CTGCACCTCGGCATACTGGCCATGGCTTGCCTGCCTGTGGCCGCCGCCCTGATCATTCTCGCTAACAAGCTGCCCGCGAA
GCGGTAG

Upstream 100 bases:

>100_bases
ACGATGTGTGAGCACAGTTGCTCTTTGCCGGCTCCCGCTGCGCTGTCACCATCGGCTCTACTAGAAGCGCCGATTGCGCG
CAATACCACAGGAGACCGGC

Downstream 100 bases:

>100_bases
CCAATCTGGAAGCAGTGCGCCGCTGCCTGGCTCGTACTGCCTTGTCAAACAGGTCCGGTTTCCGGTGGGAACGGACAAAG
AAAGGAGTCATCATGCTTTT

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MIAVPTTSAADDASSLYSKINWRLLPFLLTCYLFAYLDRVNVGFAKLQMQGDLGFSDAAYGVGAGIFFIGYVLFEIPSNL
LLPRVGARKTFSRILVLWGITSACMLFVRNVPMFYAMRFLLGVFEAGFAPGMIYYLSCWYGPQRMARAIAIVFLAGPIGG
IVGGPVSAWLMTSLAGTAGLTGWQWMFLVEGLPCILLGILALSFVPDRPADAAWLNADERRRLEAELHVPGAHKHSFMAV
AKDARVYVLALAYFCIIAAIYAISFWLPTFIKAQGVTDTVQLGWYSAIPYVAAAFGMYFMGRRSDRVGERRFHSALPALA
AGLLLGASTLADGNLVLTLALLTLATMGLWMAYTVFWAMPAEYIKGPAAAGGIALINTIGLSGGFWGPAIIGWAKTATGT
LHLGILAMACLPVAAALIILANKLPAKR

Sequences:

>Translated_428_residues
MIAVPTTSAADDASSLYSKINWRLLPFLLTCYLFAYLDRVNVGFAKLQMQGDLGFSDAAYGVGAGIFFIGYVLFEIPSNL
LLPRVGARKTFSRILVLWGITSACMLFVRNVPMFYAMRFLLGVFEAGFAPGMIYYLSCWYGPQRMARAIAIVFLAGPIGG
IVGGPVSAWLMTSLAGTAGLTGWQWMFLVEGLPCILLGILALSFVPDRPADAAWLNADERRRLEAELHVPGAHKHSFMAV
AKDARVYVLALAYFCIIAAIYAISFWLPTFIKAQGVTDTVQLGWYSAIPYVAAAFGMYFMGRRSDRVGERRFHSALPALA
AGLLLGASTLADGNLVLTLALLTLATMGLWMAYTVFWAMPAEYIKGPAAAGGIALINTIGLSGGFWGPAIIGWAKTATGT
LHLGILAMACLPVAAALIILANKLPAKR
>Mature_428_residues
MIAVPTTSAADDASSLYSKINWRLLPFLLTCYLFAYLDRVNVGFAKLQMQGDLGFSDAAYGVGAGIFFIGYVLFEIPSNL
LLPRVGARKTFSRILVLWGITSACMLFVRNVPMFYAMRFLLGVFEAGFAPGMIYYLSCWYGPQRMARAIAIVFLAGPIGG
IVGGPVSAWLMTSLAGTAGLTGWQWMFLVEGLPCILLGILALSFVPDRPADAAWLNADERRRLEAELHVPGAHKHSFMAV
AKDARVYVLALAYFCIIAAIYAISFWLPTFIKAQGVTDTVQLGWYSAIPYVAAAFGMYFMGRRSDRVGERRFHSALPALA
AGLLLGASTLADGNLVLTLALLTLATMGLWMAYTVFWAMPAEYIKGPAAAGGIALINTIGLSGGFWGPAIIGWAKTATGT
LHLGILAMACLPVAAALIILANKLPAKR

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=413, Percent_Identity=36.5617433414044, Blast_Score=237, Evalue=1e-63,
Organism=Escherichia coli, GI1789152, Length=430, Percent_Identity=23.2558139534884, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI2367379, Length=414, Percent_Identity=22.7053140096618, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082320, Length=289, Percent_Identity=20.7612456747405, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319250, Length=238, Percent_Identity=25.6302521008403, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6321698, Length=302, Percent_Identity=26.4900662251656, Blast_Score=88, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6322025, Length=196, Percent_Identity=27.0408163265306, Blast_Score=87, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6319876, Length=214, Percent_Identity=28.5046728971963, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6321502, Length=166, Percent_Identity=28.9156626506024, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323032, Length=206, Percent_Identity=29.6116504854369, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322612, Length=249, Percent_Identity=21.6867469879518, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641682, Length=187, Percent_Identity=28.3422459893048, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24584153, Length=359, Percent_Identity=22.0055710306407, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46080; Mature: 46080

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAVPTTSAADDASSLYSKINWRLLPFLLTCYLFAYLDRVNVGFAKLQMQGDLGFSDAAY
CEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHH
GVGAGIFFIGYVLFEIPSNLLLPRVGARKTFSRILVLWGITSACMLFVRNVPMFYAMRFL
HHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
LGVFEAGFAPGMIYYLSCWYGPQRMARAIAIVFLAGPIGGIVGGPVSAWLMTSLAGTAGL
HHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCC
TGWQWMFLVEGLPCILLGILALSFVPDRPADAAWLNADERRRLEAELHVPGAHKHSFMAV
CHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHEEECCCCCCHHHHHH
AKDARVYVLALAYFCIIAAIYAISFWLPTFIKAQGVTDTVQLGWYSAIPYVAAAFGMYFM
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCHHHHHHHHHHHHHHHHH
GRRSDRVGERRFHSALPALAAGLLLGASTLADGNLVLTLALLTLATMGLWMAYTVFWAMP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
AEYIKGPAAAGGIALINTIGLSGGFWGPAIIGWAKTATGTLHLGILAMACLPVAAALIIL
HHHHCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
ANKLPAKR
HHCCCCCC
>Mature Secondary Structure
MIAVPTTSAADDASSLYSKINWRLLPFLLTCYLFAYLDRVNVGFAKLQMQGDLGFSDAAY
CEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHH
GVGAGIFFIGYVLFEIPSNLLLPRVGARKTFSRILVLWGITSACMLFVRNVPMFYAMRFL
HHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
LGVFEAGFAPGMIYYLSCWYGPQRMARAIAIVFLAGPIGGIVGGPVSAWLMTSLAGTAGL
HHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCC
TGWQWMFLVEGLPCILLGILALSFVPDRPADAAWLNADERRRLEAELHVPGAHKHSFMAV
CHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHEEECCCCCCHHHHHH
AKDARVYVLALAYFCIIAAIYAISFWLPTFIKAQGVTDTVQLGWYSAIPYVAAAFGMYFM
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCHHHHHHHHHHHHHHHHH
GRRSDRVGERRFHSALPALAAGLLLGASTLADGNLVLTLALLTLATMGLWMAYTVFWAMP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
AEYIKGPAAAGGIALINTIGLSGGFWGPAIIGWAKTATGTLHLGILAMACLPVAAALIIL
HHHHCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
ANKLPAKR
HHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]