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The map label for this gene is tauD [H]

Identifier: 73538879

GI number: 73538879

Start: 1792194

End: 1793036

Strand: Direct

Name: tauD [H]

Synonym: Reut_B5054

Alternate gene names: 73538879

Gene position: 1792194-1793036 (Clockwise)

Preceding gene: 73538878

Following gene: 73538882

Centisome position: 65.74

GC content: 62.63

Gene sequence:

>843_bases
ATGCAAGTCAATCCACTTACCTGTTCGATCGGCGCCGAGCTGACCGGCGTGCAGCTTGGCAATGTCGCGCGCGACGATTC
GCTGCATGCGGAGATCAAAGCGCTGCTGCTCAAGCACCGCGTACTGTTCTTCCGCGACCAGGAGATGACGCGCGACGACC
ACGTCGCGTTCGCGAAGCGCTTCGGCGACCTGGAAGACCACCCCGTCGCCAATACGGTTCCTGGCTATCCGGGTCTCATC
GAGATCGTCAAGAGCGAGAAGCGGGACCATTTCGAGAACACCTACCACAGCGATGCCTCGTGGCGCGCGAATCCTCCCAG
GGGTGCGGTGTTGCGTTGCATCTCCTGCCCGGAGGTTGGCGGCGACACGATCTGGGTGAACATGGTCGACGCCTACAAGA
ACCTGCCCGAAGAGATCAAGCAGAAGATCGAAGGGCTGCGCGCCAAGCATGGCATCGAGCATTCGTTTGGCGCGATCATG
TCGACCGAGGAGCGCGAGGAACTGGTGCGCAAGCACCCGCTGGTCGATCATCCCGTGGTCCGGACGCATCCGGACACCGG
CGAGAAGATCTTGTACGTGACGCCGTTCTCCACGCACTTCATCAACTACCACACGCCCGAGAACGTGCGCTTCGGACAGG
ACAAGACGCCCGGCGCGAGCCTGCTGCTGAACTACCTGCTGAGCCAGGCCGCGATTCCGGAGTACCAGGTGCGTTTCCGC
TGGCGGCCGAACAGCGTGGCGATCTGGGACAACATGGCCACGCAGCATTATGCGGTCAGCGACTATTGGCCGGCCCCGCG
CAGGATGGAGCGCGCCACCATCATGGGGGATCGGCCGTTCTGA

Upstream 100 bases:

>100_bases
ACGCCTACATCGCGAGCAGCCAGCACATGGGCAAGATCGTGCTCACGGCTGACTGACCCTGACCGACTGCTGACATCCAG
ACCTTCAAGGAGTAGCCACC

Downstream 100 bases:

>100_bases
CTGCGGAACAGTTGGTGGGTTGCTCCCCTCTCGCGCGAATTGGGAGAGGGGAGCCCTGGTGTCAGCGCCTGGCCGGCTCC
AGTCCCACCGGCTTCGCATC

Product: taurine dioxygenase

Products: NA

Alternate protein names: 2-aminoethanesulfonate dioxygenase; Sulfate starvation-induced protein 3; SSI3 [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MQVNPLTCSIGAELTGVQLGNVARDDSLHAEIKALLLKHRVLFFRDQEMTRDDHVAFAKRFGDLEDHPVANTVPGYPGLI
EIVKSEKRDHFENTYHSDASWRANPPRGAVLRCISCPEVGGDTIWVNMVDAYKNLPEEIKQKIEGLRAKHGIEHSFGAIM
STEEREELVRKHPLVDHPVVRTHPDTGEKILYVTPFSTHFINYHTPENVRFGQDKTPGASLLLNYLLSQAAIPEYQVRFR
WRPNSVAIWDNMATQHYAVSDYWPAPRRMERATIMGDRPF

Sequences:

>Translated_280_residues
MQVNPLTCSIGAELTGVQLGNVARDDSLHAEIKALLLKHRVLFFRDQEMTRDDHVAFAKRFGDLEDHPVANTVPGYPGLI
EIVKSEKRDHFENTYHSDASWRANPPRGAVLRCISCPEVGGDTIWVNMVDAYKNLPEEIKQKIEGLRAKHGIEHSFGAIM
STEEREELVRKHPLVDHPVVRTHPDTGEKILYVTPFSTHFINYHTPENVRFGQDKTPGASLLLNYLLSQAAIPEYQVRFR
WRPNSVAIWDNMATQHYAVSDYWPAPRRMERATIMGDRPF
>Mature_280_residues
MQVNPLTCSIGAELTGVQLGNVARDDSLHAEIKALLLKHRVLFFRDQEMTRDDHVAFAKRFGDLEDHPVANTVPGYPGLI
EIVKSEKRDHFENTYHSDASWRANPPRGAVLRCISCPEVGGDTIWVNMVDAYKNLPEEIKQKIEGLRAKHGIEHSFGAIM
STEEREELVRKHPLVDHPVVRTHPDTGEKILYVTPFSTHFINYHTPENVRFGQDKTPGASLLLNYLLSQAAIPEYQVRFR
WRPNSVAIWDNMATQHYAVSDYWPAPRRMERATIMGDRPF

Specific function: Catalyzes the conversion of taurine and alpha ketoglutarate to sulfite, aminoacetaldehyde and succinate. Required for the utilization of taurine (2-aminoethanesulfonic acid) as an alternative sulfur source. Pentane-sulfonic acid, 3- (N-morpholino)propanes

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=287, Percent_Identity=37.2822299651568, Blast_Score=190, Evalue=7e-50,
Organism=Saccharomyces cerevisiae, GI6322971, Length=296, Percent_Identity=27.027027027027, Blast_Score=101, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: =1.14.11.17 [H]

Molecular weight: Translated: 31991; Mature: 31991

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVNPLTCSIGAELTGVQLGNVARDDSLHAEIKALLLKHRVLFFRDQEMTRDDHVAFAKR
CCCCCEEEECCCEEECEEECCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHH
FGDLEDHPVANTVPGYPGLIEIVKSEKRDHFENTYHSDASWRANPPRGAVLRCISCPEVG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCC
GDTIWVNMVDAYKNLPEEIKQKIEGLRAKHGIEHSFGAIMSTEEREELVRKHPLVDHPVV
CCEEEEEEHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHCCCCCCCCE
RTHPDTGEKILYVTPFSTHFINYHTPENVRFGQDKTPGASLLLNYLLSQAAIPEYQVRFR
EECCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEE
WRPNSVAIWDNMATQHYAVSDYWPAPRRMERATIMGDRPF
ECCCCEEEECCCCCCEEEECCCCCCCHHHHHHHCCCCCCC
>Mature Secondary Structure
MQVNPLTCSIGAELTGVQLGNVARDDSLHAEIKALLLKHRVLFFRDQEMTRDDHVAFAKR
CCCCCEEEECCCEEECEEECCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHH
FGDLEDHPVANTVPGYPGLIEIVKSEKRDHFENTYHSDASWRANPPRGAVLRCISCPEVG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCC
GDTIWVNMVDAYKNLPEEIKQKIEGLRAKHGIEHSFGAIMSTEEREELVRKHPLVDHPVV
CCEEEEEEHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHCCCCCCCCE
RTHPDTGEKILYVTPFSTHFINYHTPENVRFGQDKTPGASLLLNYLLSQAAIPEYQVRFR
EECCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEE
WRPNSVAIWDNMATQHYAVSDYWPAPRRMERATIMGDRPF
ECCCCEEEECCCCCCEEEECCCCCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8808933; 9278503; 2656410; 8774726; 7984428; 9287300; 11955067 [H]