Click here to switch to the map view.

The map label for this gene is cfxR [H]

Identifier: 73538661

GI number: 73538661

Start: 1544259

End: 1545245

Strand: Reverse

Name: cfxR [H]

Synonym: Reut_B4836

Alternate gene names: 73538661

Gene position: 1545245-1544259 (Counterclockwise)

Preceding gene: 73538664

Following gene: 73538660

Centisome position: 56.68

GC content: 65.45

Gene sequence:

>987_bases
ATGCATAAGACCACCACCTTCCGGCAGCTCAATGCGATCGACGCGGTCGCGCGCCTGGGCGGCGTATCGCGGGCAGCCGA
GGAGTTACACCTGACCCAGCCGACGGTTTCGCTGCAATTGCGGCTGCTTGAAGAGGCCACAGGCACGCCGCTGGTGCAGC
GTTCCGGGCGCGGCTTGCTGATGACGCCCGCGGGCGAAGTGATGGCAGGCTACGCGAGCCAGATCCTCAAGCTATGGCGC
GACGCGGTGGAAGAGGTAGCTGCCTTGCGCGGTGGGATCGCGGGGACCCTTCGCGTCGGCGCGATCACCACCGCCGAGTA
TTTGCTCCCGCAGATGCTGGTCGCGTTCACCCAATGCCATCCGGATGTGAAGATCGTGCTTCGGGTCGGCAACCGCGAAG
AGATCGTGCGCATGCTGGGGATGCACGAAATCGATCTCGCCATCATCGGGCGGCCGCCGTCCGAGCTCAGGACGAATGCG
GTGACCTTTGCCAAGCATCCGATGGCCTTCATTGCCGCACCCGATCATCCATTGATGGCCCGGCGGCACATCACGATGCA
AGACCTGCTTGCGGAAAACCTGCTGGTCCGCGAGCGGGGCTCTGGTACGCGCGATACCGTCGAACGCCTGTTCCGCGAGG
CGGGGCTGCGCTTGCCACACGGGTCCGAACTGTCCAGCAATGCGGCGATCAAGCGCATGGTCTCGGCCGGGCTGGGCATC
GCGTTCCTGTCGTTGCATGCCTGCACGCTGGAGTTCGAAGCGGGCTTGATCGATGTGCTGCCGCTCGCAGGCAACCCGGT
GGAGCGCGACTGGTACGTGGCGCACCTGCCGGCGGTCCGGTTGCCGCCGGTCGCGTCGGCATTCCGCGCGTTCCTGGTCG
AAAACGGGCCAGAAGAGATCCACCGGCAACTGGAATCGTTCGACGGTATTCTCAAGCGGCTGCACCAGTCCGAACGCCGG
CGGTCAAAGCGTGCGCGTGCGGGCTGA

Upstream 100 bases:

>100_bases
CGCGGAGGGGCGGCGCGATCAGGTCTTGACGTTTGCACTGTACGCGGGAAAACTCATATTGAATAATTGAGAAACAAATC
CGACCGATAGGTTTTCTTCT

Downstream 100 bases:

>100_bases
ATCATTCCCACGGGTCGGGACGCCTGCAGACGATCTTCCCTGGCGCGATTGTCCTAATGGAACGACGGACTGGTTCTATC
TCTCGCCTGCAGGATCTGAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: RuBisCO operon transcriptional regulator [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MHKTTTFRQLNAIDAVARLGGVSRAAEELHLTQPTVSLQLRLLEEATGTPLVQRSGRGLLMTPAGEVMAGYASQILKLWR
DAVEEVAALRGGIAGTLRVGAITTAEYLLPQMLVAFTQCHPDVKIVLRVGNREEIVRMLGMHEIDLAIIGRPPSELRTNA
VTFAKHPMAFIAAPDHPLMARRHITMQDLLAENLLVRERGSGTRDTVERLFREAGLRLPHGSELSSNAAIKRMVSAGLGI
AFLSLHACTLEFEAGLIDVLPLAGNPVERDWYVAHLPAVRLPPVASAFRAFLVENGPEEIHRQLESFDGILKRLHQSERR
RSKRARAG

Sequences:

>Translated_328_residues
MHKTTTFRQLNAIDAVARLGGVSRAAEELHLTQPTVSLQLRLLEEATGTPLVQRSGRGLLMTPAGEVMAGYASQILKLWR
DAVEEVAALRGGIAGTLRVGAITTAEYLLPQMLVAFTQCHPDVKIVLRVGNREEIVRMLGMHEIDLAIIGRPPSELRTNA
VTFAKHPMAFIAAPDHPLMARRHITMQDLLAENLLVRERGSGTRDTVERLFREAGLRLPHGSELSSNAAIKRMVSAGLGI
AFLSLHACTLEFEAGLIDVLPLAGNPVERDWYVAHLPAVRLPPVASAFRAFLVENGPEEIHRQLESFDGILKRLHQSERR
RSKRARAG
>Mature_328_residues
MHKTTTFRQLNAIDAVARLGGVSRAAEELHLTQPTVSLQLRLLEEATGTPLVQRSGRGLLMTPAGEVMAGYASQILKLWR
DAVEEVAALRGGIAGTLRVGAITTAEYLLPQMLVAFTQCHPDVKIVLRVGNREEIVRMLGMHEIDLAIIGRPPSELRTNA
VTFAKHPMAFIAAPDHPLMARRHITMQDLLAENLLVRERGSGTRDTVERLFREAGLRLPHGSELSSNAAIKRMVSAGLGI
AFLSLHACTLEFEAGLIDVLPLAGNPVERDWYVAHLPAVRLPPVASAFRAFLVENGPEEIHRQLESFDGILKRLHQSERR
RSKRARAG

Specific function: Trans-acting transcriptional regulator of RuBisCO genes (cfxLS) expression [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=213, Percent_Identity=32.3943661971831, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1788481, Length=299, Percent_Identity=29.4314381270903, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790399, Length=240, Percent_Identity=30, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787879, Length=241, Percent_Identity=28.6307053941909, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788748, Length=241, Percent_Identity=24.896265560166, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87081904, Length=244, Percent_Identity=27.8688524590164, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787530, Length=236, Percent_Identity=27.9661016949153, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788887, Length=269, Percent_Identity=28.6245353159851, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787601, Length=179, Percent_Identity=29.0502793296089, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082132, Length=287, Percent_Identity=24.390243902439, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1790262, Length=286, Percent_Identity=27.6223776223776, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI145693105, Length=287, Percent_Identity=22.6480836236934, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1790208, Length=241, Percent_Identity=26.9709543568465, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788296, Length=243, Percent_Identity=26.3374485596708, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788626, Length=227, Percent_Identity=27.7533039647577, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789204, Length=246, Percent_Identity=26.0162601626016, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786713, Length=299, Percent_Identity=27.7591973244147, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788297, Length=240, Percent_Identity=24.1666666666667, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI48994962, Length=142, Percent_Identity=31.6901408450704, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI2367136, Length=244, Percent_Identity=25, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36072; Mature: 36072

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKTTTFRQLNAIDAVARLGGVSRAAEELHLTQPTVSLQLRLLEEATGTPLVQRSGRGLL
CCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHCCCEEE
MTPAGEVMAGYASQILKLWRDAVEEVAALRGGIAGTLRVGAITTAEYLLPQMLVAFTQCH
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHCC
PDVKIVLRVGNREEIVRMLGMHEIDLAIIGRPPSELRTNAVTFAKHPMAFIAAPDHPLMA
CCEEEEEEECCHHHHHHHHCCCCCCEEEECCCHHHHHHCCHHHHCCCEEEEECCCCCHHH
RRHITMQDLLAENLLVRERGSGTRDTVERLFREAGLRLPHGSELSSNAAIKRMVSAGLGI
HHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHH
AFLSLHACTLEFEAGLIDVLPLAGNPVERDWYVAHLPAVRLPPVASAFRAFLVENGPEEI
HHHHHHHHEEEECCCCEEEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHH
HRQLESFDGILKRLHQSERRRSKRARAG
HHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHKTTTFRQLNAIDAVARLGGVSRAAEELHLTQPTVSLQLRLLEEATGTPLVQRSGRGLL
CCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHCCCEEE
MTPAGEVMAGYASQILKLWRDAVEEVAALRGGIAGTLRVGAITTAEYLLPQMLVAFTQCH
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHCC
PDVKIVLRVGNREEIVRMLGMHEIDLAIIGRPPSELRTNAVTFAKHPMAFIAAPDHPLMA
CCEEEEEEECCHHHHHHHHCCCCCCEEEECCCHHHHHHCCHHHHCCCEEEEECCCCCHHH
RRHITMQDLLAENLLVRERGSGTRDTVERLFREAGLRLPHGSELSSNAAIKRMVSAGLGI
HHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHH
AFLSLHACTLEFEAGLIDVLPLAGNPVERDWYVAHLPAVRLPPVASAFRAFLVENGPEEI
HHHHHHHHEEEECCCCEEEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHH
HRQLESFDGILKRLHQSERRRSKRARAG
HHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1779759 [H]