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The map label for this gene is 73538651

Identifier: 73538651

GI number: 73538651

Start: 1530125

End: 1530571

Strand: Reverse

Name: 73538651

Synonym: Reut_B4826

Alternate gene names: NA

Gene position: 1530571-1530125 (Counterclockwise)

Preceding gene: 73538652

Following gene: 73538650

Centisome position: 56.14

GC content: 66.67

Gene sequence:

>447_bases
ATGAAGCTCGTCGATCACGCGTTCAGCGGCCCGCTCGCCGCGTTGGAAGCGTCGTTGCTGCCGTCCAGGGGATGGAGCGT
GTTCATTGACGCGTTGGCGGTGCCGGTGCGAATCGGCATCCATCCACACGAGCATGAGGCACCACAGCCCATTGTCATTG
ATGCGCGCCTCGGCTATCGCTGCGAGCCGCGCGAGGAGGGCGAGTGGATCGACTACGAAGGCTATTGCGCGCGCGTCGCC
GCTTTCCTCGCGCACAGGCCGCATACGCGCCTGCTCGAGACGCTCGTGGCCGATATCGCGGAGTTGTCGTTCCGCGAATG
GCCAGCGCTCGACACGCTGACGCTCGCCGTGCACAAGCCGAAGATCCGGCCTGGCACGAAGCGGGTCGGCGTGGCACTCG
AGTGGACACGCGCCGATTACCTGCGGCGCAGCGCGAAGGCGGGCTGA

Upstream 100 bases:

>100_bases
TCGTGCCGACTGGGAATGACCGCTTCGAGATCGTGGTGCGCCGCAGCTTTGCCGATTACTTCAGCCGCATCATGCTTGAC
GCAGCGGAGCCGCTGACATC

Downstream 100 bases:

>100_bases
GCATTGCGGTGGCCGTGTCGGCATGGTTCAAACGCGTGTCGGTATTGGACATAGGTTTCGCGGTTCCTGCCACTACTCTC
GTAGACGCTGCCGCGTATGC

Product: dihydroneopterin aldolase

Products: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine; glycolaldehyde

Alternate protein names: Dihydroneopterin Aldolase Protein

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MKLVDHAFSGPLAALEASLLPSRGWSVFIDALAVPVRIGIHPHEHEAPQPIVIDARLGYRCEPREEGEWIDYEGYCARVA
AFLAHRPHTRLLETLVADIAELSFREWPALDTLTLAVHKPKIRPGTKRVGVALEWTRADYLRRSAKAG

Sequences:

>Translated_148_residues
MKLVDHAFSGPLAALEASLLPSRGWSVFIDALAVPVRIGIHPHEHEAPQPIVIDARLGYRCEPREEGEWIDYEGYCARVA
AFLAHRPHTRLLETLVADIAELSFREWPALDTLTLAVHKPKIRPGTKRVGVALEWTRADYLRRSAKAG
>Mature_148_residues
MKLVDHAFSGPLAALEASLLPSRGWSVFIDALAVPVRIGIHPHEHEAPQPIVIDARLGYRCEPREEGEWIDYEGYCARVA
AFLAHRPHTRLLETLVADIAELSFREWPALDTLTLAVHKPKIRPGTKRVGVALEWTRADYLRRSAKAG

Specific function: Unknown

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.1.2.25

Molecular weight: Translated: 16565; Mature: 16565

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLVDHAFSGPLAALEASLLPSRGWSVFIDALAVPVRIGIHPHEHEAPQPIVIDARLGYR
CCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHEEECCCCCCCCCCCCEEEECCCCCC
CEPREEGEWIDYEGYCARVAAFLAHRPHTRLLETLVADIAELSFREWPALDTLTLAVHKP
CCCCCCCCEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECC
KIRPGTKRVGVALEWTRADYLRRSAKAG
CCCCCCCEEEEEEEEHHHHHHHHHCCCC
>Mature Secondary Structure
MKLVDHAFSGPLAALEASLLPSRGWSVFIDALAVPVRIGIHPHEHEAPQPIVIDARLGYR
CCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHEEECCCCCCCCCCCCEEEECCCCCC
CEPREEGEWIDYEGYCARVAAFLAHRPHTRLLETLVADIAELSFREWPALDTLTLAVHKP
CCCCCCCCEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECC
KIRPGTKRVGVALEWTRADYLRRSAKAG
CCCCCCCEEEEEEEEHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-; $dihydropteridine

Specific reaction: 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8- $dihydropteridine = 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + glycolaldehyde

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA