Click here to switch to the map view.

The map label for this gene is ycgM [C]

Identifier: 73538504

GI number: 73538504

Start: 1373785

End: 1374639

Strand: Direct

Name: ycgM [C]

Synonym: Reut_B4678

Alternate gene names: 73538504

Gene position: 1373785-1374639 (Clockwise)

Preceding gene: 73538503

Following gene: 73538505

Centisome position: 50.39

GC content: 64.68

Gene sequence:

>855_bases
ATGAAGTTGGCAACGTTTCTGCTGGATGGCCAGCAACGAGTGGGCCTGGTATCCGACGAAGGCGTCTTCGCCTTGCCGCC
GGTTGCGGGCAAGGACGTCGGCGCCCTTATCGACGCCGGATTCGGCCCGCAGCAGTGGCACAGCCTGGTGGCCCAGGCAG
TGCCACTGCGGGACACTGCCGCGCTGACCTGGCTGCCGCCGGTCATCAGCCCGCGCAAGATCCTCTGCGTCGGGCTGAAC
TATGCGGACCATACCAAGGAGTCTCCGTACGAACAGCCCGACTACCCCACGCTGTTCCTGCGCGTGCCGACCAGCATGGT
GGGACATGACTGCGCGATCGTGCGCCCGCTCGCCAGCGACACGTTGGACTACGAGGGTGAACTCGCGGTCGTGATTGGCA
AGGGTGGCAAGCATATCGCACGGGAAGACGCCCTCAGCCATGTGTTCGGCTACTCCGTCTTCAACGACGGCTCGGTACGC
GAGTACCAGTTCAAGTCCCCGCAATGGACGGTCGGCAAGAACTTCGACGCAACCGGCGGCTTTGGTCCCTATGTCGTGAC
GGCGGACGAACTGCCCCCGGGGGCCACCGGACTCCGGCTGGAAACGCGGCTCAACGGCCAGGTGGTCCAGTCCGCCAGCA
CGTCGGACATGCTGTACGACGTGGCTTCGCTGATTGCGATCATCAGCGAAGCCATCACGCTCGAACCCGGCGACGTGATC
GTGGCCGGCACGCCGTCCGGTATCGGCTGGGCGCGCGAGCCCAAGCTGCTGATGCGCCATGGCGACGTGTGCGAAGTCAG
CATTGAACGGATCGGCACGCTGTCCAATCCGATTGCCGACGAGCAGGCGCAATAA

Upstream 100 bases:

>100_bases
ACCGAGGCCTGAGCGGCACCGCCCGCAGCCCGCACCGCTACCGTACCTTTCAACAATTCCCGCCGCGCATGGCGGCATCA
ATTCCGACTGGAGCTGGAGA

Downstream 100 bases:

>100_bases
GGCGCCGCGCGCAACGCGAATCTGGAGGAGACATCCATGAAGACGATTGAAGTACCAGTTCTCGTGGTCGGCGCCGGGCC
GGCTGGCCTTACCGCGACGG

Product: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MKLATFLLDGQQRVGLVSDEGVFALPPVAGKDVGALIDAGFGPQQWHSLVAQAVPLRDTAALTWLPPVISPRKILCVGLN
YADHTKESPYEQPDYPTLFLRVPTSMVGHDCAIVRPLASDTLDYEGELAVVIGKGGKHIAREDALSHVFGYSVFNDGSVR
EYQFKSPQWTVGKNFDATGGFGPYVVTADELPPGATGLRLETRLNGQVVQSASTSDMLYDVASLIAIISEAITLEPGDVI
VAGTPSGIGWAREPKLLMRHGDVCEVSIERIGTLSNPIADEQAQ

Sequences:

>Translated_284_residues
MKLATFLLDGQQRVGLVSDEGVFALPPVAGKDVGALIDAGFGPQQWHSLVAQAVPLRDTAALTWLPPVISPRKILCVGLN
YADHTKESPYEQPDYPTLFLRVPTSMVGHDCAIVRPLASDTLDYEGELAVVIGKGGKHIAREDALSHVFGYSVFNDGSVR
EYQFKSPQWTVGKNFDATGGFGPYVVTADELPPGATGLRLETRLNGQVVQSASTSDMLYDVASLIAIISEAITLEPGDVI
VAGTPSGIGWAREPKLLMRHGDVCEVSIERIGTLSNPIADEQAQ
>Mature_284_residues
MKLATFLLDGQQRVGLVSDEGVFALPPVAGKDVGALIDAGFGPQQWHSLVAQAVPLRDTAALTWLPPVISPRKILCVGLN
YADHTKESPYEQPDYPTLFLRVPTSMVGHDCAIVRPLASDTLDYEGELAVVIGKGGKHIAREDALSHVFGYSVFNDGSVR
EYQFKSPQWTVGKNFDATGGFGPYVVTADELPPGATGLRLETRLNGQVVQSASTSDMLYDVASLIAIISEAITLEPGDVI
VAGTPSGIGWAREPKLLMRHGDVCEVSIERIGTLSNPIADEQAQ

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=231, Percent_Identity=40.6926406926407, Blast_Score=184, Evalue=6e-47,
Organism=Homo sapiens, GI40786394, Length=231, Percent_Identity=40.2597402597403, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI215422413, Length=186, Percent_Identity=33.8709677419355, Blast_Score=111, Evalue=6e-25,
Organism=Homo sapiens, GI66348062, Length=186, Percent_Identity=33.8709677419355, Blast_Score=111, Evalue=7e-25,
Organism=Homo sapiens, GI13654274, Length=186, Percent_Identity=33.8709677419355, Blast_Score=111, Evalue=8e-25,
Organism=Escherichia coli, GI1787428, Length=188, Percent_Identity=35.1063829787234, Blast_Score=98, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17557057, Length=180, Percent_Identity=33.3333333333333, Blast_Score=107, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6324161, Length=247, Percent_Identity=27.1255060728745, Blast_Score=85, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28572127, Length=287, Percent_Identity=33.7979094076655, Blast_Score=152, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24663695, Length=279, Percent_Identity=30.4659498207885, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28571789, Length=214, Percent_Identity=29.4392523364486, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 30425; Mature: 30425

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLATFLLDGQQRVGLVSDEGVFALPPVAGKDVGALIDAGFGPQQWHSLVAQAVPLRDTA
CCEEEEEECCCHHEEEECCCCEEEECCCCCCCHHHHEECCCCHHHHHHHHHHHCCCCCCC
ALTWLPPVISPRKILCVGLNYADHTKESPYEQPDYPTLFLRVPTSMVGHDCAIVRPLASD
EEEECCCCCCCCEEEEEECCCHHCCCCCCCCCCCCCEEEEECCHHHHCCCEEEEECHHHC
TLDYEGELAVVIGKGGKHIAREDALSHVFGYSVFNDGSVREYQFKSPQWTVGKNFDATGG
CCCCCCCEEEEECCCCCCHHHHHHHHHHHHHEEECCCCCEEEEECCCCEECCCCCCCCCC
FGPYVVTADELPPGATGLRLETRLNGQVVQSASTSDMLYDVASLIAIISEAITLEPGDVI
CCCEEEECCCCCCCCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHEECCCCEE
VAGTPSGIGWAREPKLLMRHGDVCEVSIERIGTLSNPIADEQAQ
EEECCCCCCCCCCCHHHHHCCCEEEEEHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKLATFLLDGQQRVGLVSDEGVFALPPVAGKDVGALIDAGFGPQQWHSLVAQAVPLRDTA
CCEEEEEECCCHHEEEECCCCEEEECCCCCCCHHHHEECCCCHHHHHHHHHHHCCCCCCC
ALTWLPPVISPRKILCVGLNYADHTKESPYEQPDYPTLFLRVPTSMVGHDCAIVRPLASD
EEEECCCCCCCCEEEEEECCCHHCCCCCCCCCCCCCEEEEECCHHHHCCCEEEEECHHHC
TLDYEGELAVVIGKGGKHIAREDALSHVFGYSVFNDGSVREYQFKSPQWTVGKNFDATGG
CCCCCCCEEEEECCCCCCHHHHHHHHHHHHHEEECCCCCEEEEECCCCEECCCCCCCCCC
FGPYVVTADELPPGATGLRLETRLNGQVVQSASTSDMLYDVASLIAIISEAITLEPGDVI
CCCEEEECCCCCCCCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHEECCCCEE
VAGTPSGIGWAREPKLLMRHGDVCEVSIERIGTLSNPIADEQAQ
EEECCCCCCCCCCCHHHHHCCCEEEEEHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]