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The map label for this gene is oxlT [H]

Identifier: 73538491

GI number: 73538491

Start: 1358334

End: 1359668

Strand: Reverse

Name: oxlT [H]

Synonym: Reut_B4665

Alternate gene names: 73538491

Gene position: 1359668-1358334 (Counterclockwise)

Preceding gene: 73538492

Following gene: 73538490

Centisome position: 49.87

GC content: 64.12

Gene sequence:

>1335_bases
ATGGCGCATCAAGAAGCGGGAGCCACGTCCGGCAATGGTCGTGGCCTGCAGAATCGTTGGTTTCAGCTGGCCGTAGGCGT
GGTTTGCATGGGGCTGGTAGCGAACCTGCAATATGGCTGGACTCTCTTTGTGTCACCGATGGACGCCAAGCATCACTGGG
GCACGTCCGCGATCCAGGTGGCATTTTCGATCTTCATCGTCACCGAGACCTGGCTGGTGCCGCTTGAGGGCTGGCTGGTG
GACAAGTTCGGCCCGCGGCCGGTGGTGGCGGGCGGTGCACTCTGCGCCGGCCTGGCGTGGGTGATGAACGCGTATGCGAC
GACGCTGCCGGAGCTGTACGCAGCGGCGGTGATCGCAGGCATCGGGGCCGGTGGCGTGTATGGCACGTGCGTGGGCAATG
CGCTGAAGTGGTTCCCGGACAAGCGCGGCCTGGCGGCCGGCCTGACGGCGGCGGGTTTTGGCACGGGCGCGGCGATCACG
GTGATTCCCATCGCGAACATGATCCACAGCGCCGGGTACGAAAGTGCGTTCCTGTTCTTCGGCATCCTGCAAGGCGTGGC
GATTTTCGCGCTGTCGCTGCTGCTGGTGAAACCGCGCGCGCCGAAGGGTGCCGTGGCGGCGAAGGCGGTGCTGACCAACA
AGGTGGAATTCTCTCCCGGCCAGATGGTGAAGACGCCGGTGTTCTGGGTGATCTACGCAAGCTTCGTGGCAGTCGCCGCG
GGCGGGATCATGGCAACGGCGCAGCTCGGCCCGATTGCAAAGGACTATGGCTTTGCCTCGATGCCGGTGACGCTGCTGGG
CATGACGCTGCCGCTGCTGACGATGACGCTGTCGATCGACAATCTGTGCAACGGCTTCACGCGTCCGCTGTGCGGCTTTC
TATCTGACCGCTTTGGCCGCGAGAACACGATGTTCGTGATCTTCATCGGCGAGGGGCTCGCGCTCTTGGGCCTGATGCAG
TTTGGCCGCGACCCCTATGCGTTCATCTTGTTCGCAGCGCTGACCTTCCTGTTCTGGGGCGAAATCTTTTCGATCTTCCC
GGCACTGTGCGCGGACACGTTCGGCAGCAAGTTTGCGGCGTCGAACGCAGGCACGCTATACACGGCGAAGGGCACGGCGG
CGATGCTGGTGCCGCTTGCATCGATCCTGTCGGCGAATGGTGGCTGGGACGCGGTGTTCACCGTCGCGGCGGTCGTCACC
ATTGCAGCGGGGATATCGGCCAAGCTGTTGCTGGCGCCGATGCGCAAGCGGTTCATCACGGGCCATTCGGAGACGCCCAT
GCCGGTATCGGACGGGGCCTTCTTTGCGAGTGCATCGGCCAGGCGCGGCGAATAG

Upstream 100 bases:

>100_bases
CGCAATGACAGGCGCCGATCCCGTTGTGAATAGGGATGCCGAAATAGAGCACCCCAAGCAGTCCCGGCGAGGACGCAGAA
AAGCACTAGGAGACAGGTAG

Downstream 100 bases:

>100_bases
GCAATAGGCAGAGAGCATTGCCATCGCCGTACTTGTAGCGATGCATTGAAAGATTGTAGAGGCCTGGCGCATGTCGCCAG
GCCATCAGGCGCAAGCGTCT

Product: major facilitator transporter

Products: NA

Alternate protein names: OFA; Oxalate:formate antiport protein; Oxalate:formate exchange protein [H]

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MAHQEAGATSGNGRGLQNRWFQLAVGVVCMGLVANLQYGWTLFVSPMDAKHHWGTSAIQVAFSIFIVTETWLVPLEGWLV
DKFGPRPVVAGGALCAGLAWVMNAYATTLPELYAAAVIAGIGAGGVYGTCVGNALKWFPDKRGLAAGLTAAGFGTGAAIT
VIPIANMIHSAGYESAFLFFGILQGVAIFALSLLLVKPRAPKGAVAAKAVLTNKVEFSPGQMVKTPVFWVIYASFVAVAA
GGIMATAQLGPIAKDYGFASMPVTLLGMTLPLLTMTLSIDNLCNGFTRPLCGFLSDRFGRENTMFVIFIGEGLALLGLMQ
FGRDPYAFILFAALTFLFWGEIFSIFPALCADTFGSKFAASNAGTLYTAKGTAAMLVPLASILSANGGWDAVFTVAAVVT
IAAGISAKLLLAPMRKRFITGHSETPMPVSDGAFFASASARRGE

Sequences:

>Translated_444_residues
MAHQEAGATSGNGRGLQNRWFQLAVGVVCMGLVANLQYGWTLFVSPMDAKHHWGTSAIQVAFSIFIVTETWLVPLEGWLV
DKFGPRPVVAGGALCAGLAWVMNAYATTLPELYAAAVIAGIGAGGVYGTCVGNALKWFPDKRGLAAGLTAAGFGTGAAIT
VIPIANMIHSAGYESAFLFFGILQGVAIFALSLLLVKPRAPKGAVAAKAVLTNKVEFSPGQMVKTPVFWVIYASFVAVAA
GGIMATAQLGPIAKDYGFASMPVTLLGMTLPLLTMTLSIDNLCNGFTRPLCGFLSDRFGRENTMFVIFIGEGLALLGLMQ
FGRDPYAFILFAALTFLFWGEIFSIFPALCADTFGSKFAASNAGTLYTAKGTAAMLVPLASILSANGGWDAVFTVAAVVT
IAAGISAKLLLAPMRKRFITGHSETPMPVSDGAFFASASARRGE
>Mature_443_residues
AHQEAGATSGNGRGLQNRWFQLAVGVVCMGLVANLQYGWTLFVSPMDAKHHWGTSAIQVAFSIFIVTETWLVPLEGWLVD
KFGPRPVVAGGALCAGLAWVMNAYATTLPELYAAAVIAGIGAGGVYGTCVGNALKWFPDKRGLAAGLTAAGFGTGAAITV
IPIANMIHSAGYESAFLFFGILQGVAIFALSLLLVKPRAPKGAVAAKAVLTNKVEFSPGQMVKTPVFWVIYASFVAVAAG
GIMATAQLGPIAKDYGFASMPVTLLGMTLPLLTMTLSIDNLCNGFTRPLCGFLSDRFGRENTMFVIFIGEGLALLGLMQF
GRDPYAFILFAALTFLFWGEIFSIFPALCADTFGSKFAASNAGTLYTAKGTAAMLVPLASILSANGGWDAVFTVAAVVTI
AAGISAKLLLAPMRKRFITGHSETPMPVSDGAFFASASARRGE

Specific function: Anion transporter that carries out the exchange of divalent oxalate with monovalent formate, the product of oxalate decarboxylation, at the plasma membrane, and in doing so catalyzes the vectorial portion of a proton-motive metabolic cycle that drives ATP

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. OFA (TC 2.A.1.11) family [H]

Homologues:

Organism=Escherichia coli, GI1789969, Length=412, Percent_Identity=23.7864077669903, Blast_Score=96, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004741 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46503; Mature: 46372

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHQEAGATSGNGRGLQNRWFQLAVGVVCMGLVANLQYGWTLFVSPMDAKHHWGTSAIQV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHH
AFSIFIVTETWLVPLEGWLVDKFGPRPVVAGGALCAGLAWVMNAYATTLPELYAAAVIAG
HHHHHEEEHHHEEECCCEEECCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGAGGVYGTCVGNALKWFPDKRGLAAGLTAAGFGTGAAITVIPIANMIHSAGYESAFLFF
CCCCCHHHHHHHHHHHHCCCCCCCHHCCHHCCCCCCCEEEEHHHHHHHHHCCCCHHHHHH
GILQGVAIFALSLLLVKPRAPKGAVAAKAVLTNKVEFSPGQMVKTPVFWVIYASFVAVAA
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHH
GGIMATAQLGPIAKDYGFASMPVTLLGMTLPLLTMTLSIDNLCNGFTRPLCGFLSDRFGR
CCHHEEHHCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ENTMFVIFIGEGLALLGLMQFGRDPYAFILFAALTFLFWGEIFSIFPALCADTFGSKFAA
CCCEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHC
SNAGTLYTAKGTAAMLVPLASILSANGGWDAVFTVAAVVTIAAGISAKLLLAPMRKRFIT
CCCCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
GHSETPMPVSDGAFFASASARRGE
CCCCCCCCCCCCCEEECCCCCCCC
>Mature Secondary Structure 
AHQEAGATSGNGRGLQNRWFQLAVGVVCMGLVANLQYGWTLFVSPMDAKHHWGTSAIQV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHH
AFSIFIVTETWLVPLEGWLVDKFGPRPVVAGGALCAGLAWVMNAYATTLPELYAAAVIAG
HHHHHEEEHHHEEECCCEEECCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGAGGVYGTCVGNALKWFPDKRGLAAGLTAAGFGTGAAITVIPIANMIHSAGYESAFLFF
CCCCCHHHHHHHHHHHHCCCCCCCHHCCHHCCCCCCCEEEEHHHHHHHHHCCCCHHHHHH
GILQGVAIFALSLLLVKPRAPKGAVAAKAVLTNKVEFSPGQMVKTPVFWVIYASFVAVAA
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHH
GGIMATAQLGPIAKDYGFASMPVTLLGMTLPLLTMTLSIDNLCNGFTRPLCGFLSDRFGR
CCHHEEHHCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ENTMFVIFIGEGLALLGLMQFGRDPYAFILFAALTFLFWGEIFSIFPALCADTFGSKFAA
CCCEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHC
SNAGTLYTAKGTAAMLVPLASILSANGGWDAVFTVAAVVTIAAGISAKLLLAPMRKRFIT
CCCCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
GHSETPMPVSDGAFFASASARRGE
CCCCCCCCCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8636101; 9651403; 11919184; 11113128; 11274108; 11500368 [H]